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  1. Article: Focus on the cetirizine use in clinical practice: a reappraisal 30 years later

    Ciprandi, Giorgio

    Multidisciplinary respiratory medicine, 14:40

    2019  

    Abstract: Antihistamines are currently one of the most commonly administered categories of drugs. They are used to treat symptoms that are secondary to histamine release, which is typical of certain allergic conditions, including rhinitis, conjunctivitis, asthma, ... ...

    Abstract Antihistamines are currently one of the most commonly administered categories of drugs. They are used to treat symptoms that are secondary to histamine release, which is typical of certain allergic conditions, including rhinitis, conjunctivitis, asthma, urticaria, and anaphylaxis. Cetirizine belongs to the second-generation family, so, it is very selective for peripheral H1 receptors, is potent and quickly relieves symptoms, exerts additional anti-allergic/anti-inflammatory effects, and is usually well-tolerated. It has been marketed 30 years ago. In these years, a remarkable body of evidence has been built. The current review provides a practical update on the use of cetirizine in clinical practice.
    Keywords Cetirizine ; Clinical practice ; Antihistamines ; H1 receptors ; Histamine
    Language English
    Document type Article
    Database Repository for Life Sciences

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  2. Article ; Online: Budenoside aqueous nasal spray: an updated reappraisal in rhinitis management.

    Ciprandi, Giorgio

    Minerva medica

    2024  

    Abstract: Allergic rhinitis (AR) and nonallergic rhinitis are prevalent diseases. In western countries, type 2 inflammation usually characterizes these medical conditions and mainly sustains nasal obstruction. Budesonide aqueous nasal spray (BANS) is an intranasal ...

    Abstract Allergic rhinitis (AR) and nonallergic rhinitis are prevalent diseases. In western countries, type 2 inflammation usually characterizes these medical conditions and mainly sustains nasal obstruction. Budesonide aqueous nasal spray (BANS) is an intranasal corticosteroid (INCS) that has been available since the early 1980s. BANS is indicated for treating allergic rhinitis, nonallergic rhinitis, and nasal polyps (both as treatment and prevention after surgery). Consolidated evidence confirms its efficacy in treating seasonal and perennial AR, and nonallergic rhinitis. In addition, BANS is safe with negligible local and systemic side effects. Recent guidelines for patients with AR recommend using INCS as the first line in many situations. In particular, patients may assess the perception of symptoms' severity using the Visual Analog Scale. A score ≥5/10 means uncontrolled symptoms and requires adequate treatment. BANS could appropriately be used in patients with uncontrolled symptoms and/or moderate/severe nasal obstruction. In conclusion, BANS represents a valuable option in managing patients with type 2 inflammation of the nose.
    Language English
    Publishing date 2024-02-28
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 123586-2
    ISSN 1827-1669 ; 0026-4806
    ISSN (online) 1827-1669
    ISSN 0026-4806
    DOI 10.23736/S0026-4806.24.09214-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  3. Article ; Online: The updated role of budesonide in managing children and adolescents with allergic rhinitis.

    Ciprandi, Giorgio

    Minerva pediatrics

    2024  

    Abstract: Allergic rhinitis (AR) is a prevalent disease in childhood and adolescence. A type 2 inflammation characterizes AR and, mainly, sustains nasal obstruction. Budesonide aqueous nasal spray (BANS) is an intranasal corticosteroid (INCS) available since the ... ...

    Abstract Allergic rhinitis (AR) is a prevalent disease in childhood and adolescence. A type 2 inflammation characterizes AR and, mainly, sustains nasal obstruction. Budesonide aqueous nasal spray (BANS) is an intranasal corticosteroid (INCS) available since the early 1980s. BANS is indicated for treating allergic rhinitis. There is evidence about its efficacy in treating children and adolescents with seasonal and perennial AR. In addition, BANS is safe with negligible local and systemic side effects. Recent guidelines for patients with AR recommend the use of INCS as first line in many situations. In particular, AR patients (and their parents) may assess the perception of symptoms' severity using the Visual Analog Scale (VAS). A score ≥5/10 means uncontrolled symptoms and requires adequate treatment. BANS could appropriately be used in patients with uncontrolled symptoms and/or moderate/severe nasal obstruction. In conclusion, BANS represents a valuable option in managing children and adolescents with AR.
    Language English
    Publishing date 2024-02-26
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3062664-X
    ISSN 2724-5780
    ISSN (online) 2724-5780
    DOI 10.23736/S2724-5276.24.07538-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Self-Management in Allergic Rhinitis: Strategies, Outcomes and Integration into Clinical Care.

    Ciprandi, Giorgio

    Journal of asthma and allergy

    2023  Volume 16, Page(s) 1087–1095

    Abstract: Allergic rhinitis (AR) is a common disease, characterized by typical symptoms and type 2 inflammation. Standard treatment is usually effective and safe, and most medications are available as over-the-counter (OTC). Therefore, AR patients, mostly at the ... ...

    Abstract Allergic rhinitis (AR) is a common disease, characterized by typical symptoms and type 2 inflammation. Standard treatment is usually effective and safe, and most medications are available as over-the-counter (OTC). Therefore, AR patients, mostly at the AR onset or if symptoms are mild, prefer to manage symptoms themselves. However, self-management could be associated with problems, including inadequate control or medication abuse. Therefore, this paper aimed at presenting and discussing this issue. Ideally, self-management should be conducted under medical supervision. In this regard, telemedicine could represent a valuable tool for implementing self-management. Visual analog scale (VAS) is a perfect parameter to measure symptom severity, medications use, and AR control. In addition, VAS is easily monitored over time. Presently, a mobile application allows to AR patients of self-managing themselves. Therefore, mobile healthcare may supply fundamental support in communication and decision-making. In this regard, VAS represents the best tool to monitor symptoms' severity and control over time. Finally, pharmacological and non-pharmacological remedies are numerous and effective but should be used wisely.
    Language English
    Publishing date 2023-10-05
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2494877-9
    ISSN 1178-6965
    ISSN 1178-6965
    DOI 10.2147/JAA.S273478
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Pediatric Asthma: A Daily Challenge.

    Ciprandi, Giorgio

    Children (Basel, Switzerland)

    2022  Volume 9, Issue 4

    Abstract: Asthma is a prevalent disease in children and adolescents, as the prevalence concerns about 10% of the general pediatric population [ ... ]. ...

    Abstract Asthma is a prevalent disease in children and adolescents, as the prevalence concerns about 10% of the general pediatric population [...].
    Language English
    Publishing date 2022-04-18
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2732685-8
    ISSN 2227-9067
    ISSN 2227-9067
    DOI 10.3390/children9040576
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Tablet allergen immunotherapy (TAIT) requires tight management.

    Ciprandi, Giorgio

    Allergo journal international

    2021  Volume 30, Issue 2, Page(s) 76–77

    Language English
    Publishing date 2021-01-11
    Publishing country Germany
    Document type Journal Article
    ISSN 2197-0378
    ISSN 2197-0378
    DOI 10.1007/s40629-020-00159-x
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  7. Article ; Online: Role of FEF25-75 in characterizing outpatients with asthma in clinical practice.

    Ciprandi, Giorgio / Schiavetti, Irene

    Allergologie select

    2024  Volume 8, Page(s) 12–17

    Abstract: Background: Asthma is characterized by variable airflow limitation. FEF: Objectives: To investigate the role of FEF: Materials and methods: The cross-sectional study included 439 (181 females and 255 males; mean age 39 years) outpatients with ... ...

    Abstract Background: Asthma is characterized by variable airflow limitation. FEF
    Objectives: To investigate the role of FEF
    Materials and methods: The cross-sectional study included 439 (181 females and 255 males; mean age 39 years) outpatients with asthma who consecutively visited an allergy clinic for a routine assessment. History, physical examination, asthma control, and spirometry were evaluated.
    Results: FEF
    Conclusion: FEF
    Language English
    Publishing date 2024-01-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2893503-2
    ISSN 2512-8957 ; 2512-8957
    ISSN (online) 2512-8957
    ISSN 2512-8957
    DOI 10.5414/ALX02453E
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  8. Book ; Conference proceedings: Rhinitis may not just be allergic

    Ciprandi, Giorgio

    proceedings of the VIATRIS satellite symposium, EAACI 2002, Naples

    (Allergy : Supplement ; 76)

    2004  

    Institution VIATRIS GmbH & Co. KG
    Author's details guest ed.: G. Ciprandi
    Series title Allergy : Supplement ; 76
    Allergy
    Allergy ; Supplement
    Collection Allergy
    Allergy ; Supplement
    Language English
    Size 23 S. : Ill.
    Publisher Munksgaard
    Publishing place Copenhagen
    Publishing country Denmark
    Document type Book ; Conference proceedings
    HBZ-ID HT013914798
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    Uh III Zs 150 -Suppl.76- verfügbar in Königswinter Königswinter

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  9. Article: Sobrerol: New Perspectives to Manage Patients with Frequent Respiratory Infections.

    Ciprandi, Giorgio / Varriccchio, Attilio

    Children (Basel, Switzerland)

    2023  Volume 10, Issue 7

    Abstract: Respiratory tract infections (RTIs) are usually characterized by mucus hypersecretion. This condition may worsen and prolong symptoms and signs. For this reason, reducing mucus production and improving mucus removal represent relevant aspects of managing ...

    Abstract Respiratory tract infections (RTIs) are usually characterized by mucus hypersecretion. This condition may worsen and prolong symptoms and signs. For this reason, reducing mucus production and improving mucus removal represent relevant aspects of managing patients with RTIs. In this regard, mucoactive drugs may be effective. Mucoactive agents constitute a large class of compounds characterized by different mechanisms of action. Sobrerol is a monoterpene able to fluidify mucus, increase mucociliary clearance, and exert antioxidant activity. Sobrerol is available in various formulations (granules, syrup, nebulized, and suppository). Sobrerol has been on the market for over 50 years. Therefore, the present article revised the evidence concerning this compound and proposed new possible strategies. The literature analysis showed that several studies investigated the efficacy and safety of sobrerol in acute and chronic RTIs characterized by mucus hyperproduction. Seven pediatric studies have been conducted with favorable outcomes. However, the regulatory agencies recently reduced the treatment duration to three days. Therefore, a future study will test the hypothesis that a combination of oral and topical sobrerol could benefit children and adults with frequent respiratory tract infections. The rationale of this new approach is based on the concept that mucus accumulation could be a risk factor for increased susceptibility to infections.
    Language English
    Publishing date 2023-07-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2732685-8
    ISSN 2227-9067
    ISSN 2227-9067
    DOI 10.3390/children10071210
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  10. Article ; Online: Eye involvement in patient with gastric reflux: an intriguing contingency.

    Damiani, Valerio / Ciprandi, Giorgio

    Minerva gastroenterology

    2023  

    Language English
    Publishing date 2023-08-03
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 3062713-8
    ISSN 2724-5365
    ISSN (online) 2724-5365
    DOI 10.23736/S2724-5985.23.03509-X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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