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  1. Article ; Online: Technological Solutions for Diagnosis, Management and Treatment of Alzheimer's Disease-Related Symptoms: A Structured Review of the Recent Scientific Literature.

    Cammisuli, Davide Maria / Cipriani, Gabriele / Castelnuovo, Gianluca

    International journal of environmental research and public health

    2022  Volume 19, Issue 5

    Abstract: In people with Alzheimer's disease (PwAD), there is a need for specific tools for the timely diagnosis, management, and treatment of symptoms. New technological solutions, including digital devices, application programs (apps), sensors and virtual ... ...

    Abstract In people with Alzheimer's disease (PwAD), there is a need for specific tools for the timely diagnosis, management, and treatment of symptoms. New technological solutions, including digital devices, application programs (apps), sensors and virtual reality, represent promising possibilities for objective and reliable assessment, monitoring and intervention strategies in this field. Our structured review presents an up-to-date summary of the technological solutions for the (i) diagnosis, (ii) management and (iii) treatment of AD-related symptoms. To this end, we searched electronic databases (i.e., PubMed, Web of Science, and Cochrane Library) for studies published over the last 10 years. Two authors of the review extracted data of interest. A total of eight manuscripts were included. In the last decade, a series of technological solutions across AD stages have been proposed. These include: (i) innovative strategies for the early detection of deficits in finger dexterity, visuo-spatial abilities (including spatial navigation), divided attention and instrumental autonomy; (ii) tools to activate the patient's responsiveness in terms of alertness and mood improvement; and (iii) useful interventions for retrieving memories, increasing body movements and improving spatial cognition. Methodological limitations, mainly pertaining to the paucity of randomized controlled trials and comprehensive assessments, were observed. Advances in technology currently provide the potential for designing innovative methods for evaluating, controlling and handling AD-related symptoms. The co-creation of technological solutions with all stakeholders represents the best way to design effective strategies for PwAD.
    MeSH term(s) Alzheimer Disease/diagnosis ; Alzheimer Disease/physiopathology ; Alzheimer Disease/therapy ; Cognition ; Humans ; Motor Skills
    Language English
    Publishing date 2022-03-07
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph19053122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Access to Care for Dementia Patients Suffering From COVID-19.

    Cipriani, Gabriele / Fiorino, Mario Di

    The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry

    2020  Volume 28, Issue 7, Page(s) 796–797

    MeSH term(s) Aged ; Aged, 80 and over ; Betacoronavirus ; COVID-19 ; Comorbidity ; Coronavirus Infections/mortality ; Coronavirus Infections/psychology ; Coronavirus Infections/therapy ; Dementia/epidemiology ; Dementia/therapy ; Health Services Accessibility/ethics ; Health Services Accessibility/standards ; Health Services Accessibility/trends ; Health Services Needs and Demand ; Homes for the Aged/ethics ; Homes for the Aged/trends ; Humans ; Infection Control/organization & administration ; Italy/epidemiology ; Mortality ; Nursing Homes/ethics ; Nursing Homes/trends ; Pandemics ; Patient Selection/ethics ; Pneumonia, Viral/mortality ; Pneumonia, Viral/psychology ; Pneumonia, Viral/therapy ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-04-17
    Publishing country England
    Document type Letter
    ZDB-ID 1278145-9
    ISSN 1545-7214 ; 1064-7481
    ISSN (online) 1545-7214
    ISSN 1064-7481
    DOI 10.1016/j.jagp.2020.04.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Effects of Reminiscence Therapy on Cognition, Depression and Quality of Life in Elderly People with Alzheimer's Disease: A Systematic Review of Randomized Controlled Trials.

    Cammisuli, Davide Maria / Cipriani, Gabriele / Giusti, Emanuele Maria / Castelnuovo, Gianluca

    Journal of clinical medicine

    2022  Volume 11, Issue 19

    Abstract: Background: Patients with Alzheimer's disease (AD) present with cognitive function deterioration, neuropsychiatric symptoms (NPS)-especially depression-and low quality of life (QoL). Management of AD remains difficult, especially in the elderly. ... ...

    Abstract Background: Patients with Alzheimer's disease (AD) present with cognitive function deterioration, neuropsychiatric symptoms (NPS)-especially depression-and low quality of life (QoL). Management of AD remains difficult, especially in the elderly. Reminiscence therapy (RT) is a well-known cognitive rehabilitation intervention that can be adopted in nursing and residential care homes to restore autobiographical memory, ameliorate NPS, and improve the QoL of people with dementia. However, the evidence-based efficacy of RT for elderly patients with AD remains to be determined.
    Methods: Here, we synthesized findings of randomized controlled trials (RCTs) exploring the effects of RT on cognition, depression, and QoL in elderly people with AD, according to the most recent PRISMA statement. We searched for RCTs in PubMed, Web of Science, and Cochrane Central Register of Controlled Trials, and in trial registries (i.e., clinicaltrials.gov and International Clinical Trials Registry Platform of the World Health Organization). Two review authors extracted data of interest, with cognition, depression, and QoL measures as outcomes.
    Results: A total of five articles were included in the final analysis. Findings globally showed that RT, both administered in individual or group sessions at least once a week for 30-35 min over a period of 12 weeks, is effective in supporting global cognition, ameliorating depression, and improving specific aspects of the QoL in elderly people with AD.
    Conclusions: RT has the potential to be a routine non-pharmacological therapy for elderly people with AD, thanks to its wider effects on the individual in terms of cognitive vitality and emotional status promotion, with positive implications for patient's daily life. Despite such evidences, caution should be used in findings' generalizability in relation to the paucity of existing RCTs with long-term follow-up.
    Language English
    Publishing date 2022-09-28
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11195752
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Dementia in the era of COVID-19. Some considerations and ethical issues.

    Cipriani, Gabriele / Di Fiorino, Mario / Cammisuli, Davide M

    Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society

    2021  Volume 22, Issue 1, Page(s) 132–136

    Abstract: Living with dementia at any time brings everyday challenges for the patient and those around him/her. The Covid-19 pandemic is making daily life harder. We aim to describe the problems of people with dementia during the time of such a pandemic and ... ...

    Abstract Living with dementia at any time brings everyday challenges for the patient and those around him/her. The Covid-19 pandemic is making daily life harder. We aim to describe the problems of people with dementia during the time of such a pandemic and address the issue of their access to intensive care units. A systematic literature search (Cochrane Library (advanced search), and PubMed) was performed (for items up to 19 August 2020) using the following terms: 'COVID-19', 'dementia', and 'intensive care unit'. Studies were independently evaluated and selected for potential analysis. Five of 35 articles initially selected met the inclusion criteria. An additional Google Scholar search identified some striking statements from relevant authorities or scientists about the difficulty of living with dementia in the era of COVID-19, and were also reported. To summarize, dementia-related behaviours, increased age, and comorbid health conditions may increase the risk of contracting the virus. People with dementia in their own homes may already feel isolated, and additional rules for self-isolation may make this worse. As COVID-19 is spreading worldwide, governments and health authorities should devise better criteria for accessing intensive care units and allocating ventilators. If someone is given preference for medical care, it should be because that person has a better short-term prognosis, not simply because that person is younger than someone else.
    MeSH term(s) COVID-19 ; Dementia/epidemiology ; Female ; Humans ; Male ; Pandemics ; SARS-CoV-2
    Language English
    Publishing date 2021-11-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2213105-X
    ISSN 1479-8301 ; 1346-3500
    ISSN (online) 1479-8301
    ISSN 1346-3500
    DOI 10.1111/psyg.12773
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Euthanasia and other end of life in patients suffering from dementia.

    Cipriani, Gabriele / Di Fiorino, Mario

    Legal medicine (Tokyo, Japan)

    2019  Volume 40, Page(s) 54–59

    Abstract: Medicine aims to relieve patient suffering and cure illness. To relieve suffering is the heart of what doctors do. However, respect for individual autonomy and self-determination are fundamental principles in Western medical ethics and decision-making, ... ...

    Abstract Medicine aims to relieve patient suffering and cure illness. To relieve suffering is the heart of what doctors do. However, respect for individual autonomy and self-determination are fundamental principles in Western medical ethics and decision-making, often expressed as a desire for control over the timing and manner of death. Patients who become demented often formulate advance euthanasia and assisted suicide directives. Dealing with such request is quite complex because of the specific medical and conflicting ethical questions they raise. Some specific medical and ethical issues arise regarding these substantive requirements when evaluating the euthanasia request of a person suffering from dementia. In jurisdictions that allow euthanasia, the most fundamental prerequisite for a person to make autonomous decisions is capacity. Whether anyone with moderate or severe dementia, and even some with mild dementia, could be deemed to be competent by these criteria is debatable, but during the course of their disease people with dementia sooner or later lose their capacity to make self-determined decisions.
    MeSH term(s) Advance Directives ; Cultural Characteristics ; Decision Making ; Dementia ; Humans ; Mental Competency ; Stress, Psychological ; Suicide, Assisted/ethics
    Language English
    Publishing date 2019-07-22
    Publishing country Ireland
    Document type Journal Article ; Review
    ZDB-ID 2019555-2
    ISSN 1873-4162 ; 1344-6223
    ISSN (online) 1873-4162
    ISSN 1344-6223
    DOI 10.1016/j.legalmed.2019.07.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Access to Care for Dementia Patients Suffering From COVID-19

    Cipriani, Gabriele / Fiorino, Mario Di

    The American Journal of Geriatric Psychiatry

    2020  Volume 28, Issue 7, Page(s) 796–797

    Keywords Geriatrics and Gerontology ; Psychiatry and Mental health ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ZDB-ID 1278145-9
    ISSN 1545-7214 ; 1064-7481
    ISSN (online) 1545-7214
    ISSN 1064-7481
    DOI 10.1016/j.jagp.2020.04.009
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Book ; Online: Financing the EU Budget

    Cipriani, Gabriele

    Moving Forward or Backwards?

    2014  

    Abstract: ... Gabriele Cipriani presents a historical overview of the EU revenue system, the context for revenue-raising arrangements and the concept of the EU's 'own resources'. He assesses the current system against issues of simplicity, transparency, ... ...

    Abstract Gabriele Cipriani presents a historical overview of the EU revenue system, the context for revenue-raising arrangements and the concept of the EU's 'own resources'. He assesses the current system against issues of simplicity, transparency, equity and democratic accountability. He outlines two possible options for reforming the EU revenue system.
    Language English
    Size Online-Ressource (113 p)
    Publisher Rowman & Littlefield International
    Publishing place London
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9781783483303 ; 178348330X
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  8. Article: The EU budget

    Cipriani, Gabriele

    The aftermath of the global crisis in the European Union , p. 56-82

    a "Trojan Horse" for better national spending?

    2013  , Page(s) 56–82

    Author's details Gabriele Cipriani
    Language Undetermined
    Publisher Cambridge Scholars Publ.
    Publishing place Newcastle upon Tyne
    Document type Article
    ISBN 1-4438-4620-1 ; 978-1-4438-4620-2
    Database ECONomics Information System

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  9. Article ; Online: Danger in the Air: Air Pollution and Cognitive Dysfunction.

    Cipriani, Gabriele / Danti, Sabrina / Carlesi, Cecilia / Borin, Gemma

    American journal of Alzheimer's disease and other dementias

    2018  Volume 33, Issue 6, Page(s) 333–341

    Abstract: Background: Clean air is considered to be a basic requirement for human health and well-being.: Objective: To examine the relationship between cognitive performance and ambient pollution exposure.: Methods: Studies were identified through a ... ...

    Abstract Background: Clean air is considered to be a basic requirement for human health and well-being.
    Objective: To examine the relationship between cognitive performance and ambient pollution exposure.
    Methods: Studies were identified through a systematic search of online scientific databases, in addition to a manual search of the reference lists from the identified papers.
    Results: Air pollution is a multifaceted toxic chemical mixture capable of assaulting the central nervous system. Despite being a relatively new area of investigation, overall, there is mounting evidence implicating adverse effects of air pollution on cognitive function in both adults and children.
    Conclusions: Consistent evidence showed that exposure to air pollution, specifically exposure to particulate matter, caused poor age-related cognitive performance. Living in areas with high levels of air pollution has been linked to markers of neuroinflammation and neuropathology that are associated with neurodegenerative conditions such as Alzheimer's disease-like brain pathologies.
    MeSH term(s) Age Factors ; Air Pollution/adverse effects ; Cognitive Dysfunction/etiology ; Cognitive Dysfunction/physiopathology ; Dementia/chemically induced ; Dementia/complications ; Humans ; Particulate Matter/adverse effects
    Chemical Substances Particulate Matter
    Language English
    Publishing date 2018-06-06
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 1283069-0
    ISSN 1938-2731 ; 0895-5336 ; 1082-5207 ; 1533-3175
    ISSN (online) 1938-2731
    ISSN 0895-5336 ; 1082-5207 ; 1533-3175
    DOI 10.1177/1533317518777859
    Database MEDical Literature Analysis and Retrieval System OnLINE

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