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  1. Article ; Online: Anatomical study about the variations in renal vasculature.

    García-Barrios, Alberto / Cisneros-Gimeno, Ana I / Celma-Pitarch, Andrea / Whyte-Orozco, Jaime

    Folia morphologica

    2023  

    Abstract: Renal vascularization is classically described as a renal artery and vein. However, this vascular pattern presents numerous anatomical variations in terms of their number, origin and course due to ontogenetic alterations. The aim was to carry out a ... ...

    Abstract Renal vascularization is classically described as a renal artery and vein. However, this vascular pattern presents numerous anatomical variations in terms of their number, origin and course due to ontogenetic alterations. The aim was to carry out a descriptive study of the renal vascular pattern observed during the dissection of cadavers intended for teaching purposes. A descriptive and observational study of renal vascular anatomy was carried out by dissecting 16 renal blocks from 8 cadavers donated to science and used for teaching at the Faculty of Medicine of the University of Zaragoza. The prevalence of arterial variations was 75% (56.3% for polar renal arteries, 12.5% for pre-hilar branching and 6.25% for double communicating arterial arch) and venous was 62.5% (12.5% for polar renal veins, 25% for late venous confluence, 6.25% for triple renal vein and 18.75% for double circumaortic renal vein). We conclude that the renal vascular anomalies occur with high frequency; for this reason, knowledge of these anomalies is extremely important for the correct planning of numerous medical-surgical activities.
    Language English
    Publishing date 2023-06-07
    Publishing country Poland
    Document type Journal Article
    ZDB-ID 419361-1
    ISSN 1644-3284 ; 0015-5659
    ISSN (online) 1644-3284
    ISSN 0015-5659
    DOI 10.5603/FM.a2023.0039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Are Comorbidities Associated With Overall Survival in Patients With Oral Squamous Cell Carcinoma?

    Jariod-Ferrer, Úrsula M / Arbones-Mainar, Jose M / Gavin-Clavero, Marina A / Simón-Sanz, M Victoria / Moral-Saez, Ignacio / Cisneros-Gimeno, Ana I / Martinez-Trufero, Javier

    Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons

    2019  Volume 77, Issue 9, Page(s) 1906–1914

    Abstract: Purpose: Oral squamous cell carcinoma (OSCC) is a highly prevalent type of immunogenic cancer with a low survival rate in patients with comorbidities owing to toxic habits.: Materials and methods: A retrospective cohort study was conducted of ... ...

    Abstract Purpose: Oral squamous cell carcinoma (OSCC) is a highly prevalent type of immunogenic cancer with a low survival rate in patients with comorbidities owing to toxic habits.
    Materials and methods: A retrospective cohort study was conducted of patients with resectable OSCC at a tertiary Spanish hospital from 2011 to 2014. The primary predictor variables were comorbidity and immune biomarkers. Comorbidity was assessed using the Adult Comorbidity Evaluation-27 (ACE-27) and scored from 1 to 3 (mild to severe decompensation, respectively). The immune biomarkers were neutrophil-to-lymphocyte ratio (NLR), derived NLR (dNLR), platelet-to-lymphocyte ratio (PLR), and lymphocyte-to-monocyte ratio (LMR). The primary outcome variable was 5-year overall survival (OS). Other study variables were stage, margin, and neck management. Receiver operating characteristic curves were built for each ratio. For the survey of immune biomarkers, area under the curve was computed to determine cutoff points and investigate their association with OS. Kaplan-Meier estimates of survival and Cox proportional hazards models were used for longitudinal analysis.
    Results: Overall 215 patients were identified (median age, 67 yr; range, 32 to 96 yr; median follow-up, 31 months; range, 7 to 78 months); 159 patients had at least 1 comorbid condition. Results showed that a severe comorbidity (according to the ACE-27) increased the risk of death by 4 times in patients with OSCC regardless of stage. NLR, dNLR, LMR, and PLR were associated with OS in the univariate study. Cutoff points to predict increased mortality were 3, 1.9, 2.6, and 66 for NLR, dNLR, LMR, and PLR, respectively. Age, comorbidity, stage, margins, and management of the neck were important independent predictors of decreased OS in OSCC. PLR was marginally associated with OS in the multivariate model.
    Conclusion: These results suggest that comorbidity and NLR, dNLR, LMR, and PLR are associated with 5-year OS in patients with resectable OSCC.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Carcinoma, Squamous Cell/mortality ; Carcinoma, Squamous Cell/surgery ; Comorbidity ; Humans ; Middle Aged ; Mouth Neoplasms/mortality ; Mouth Neoplasms/surgery ; Neutrophils ; Prognosis ; Retrospective Studies
    Language English
    Publishing date 2019-03-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 392404-x
    ISSN 1531-5053 ; 0278-2391
    ISSN (online) 1531-5053
    ISSN 0278-2391
    DOI 10.1016/j.joms.2019.03.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Contribution to morphological knowledge of the development of the human incudo-mallear joint.

    Cisneros Gimeno, Ana I / Whyte Orozco, Jaime R / Obón Nogues, Jesús Angel / Yus Gotor, Carmen / Crovetto De La Torre, Miguel Angel / Whyte Orozco, Ana

    Acta oto-laryngologica

    2009  Volume 129, Issue 12, Page(s) 1380–1387

    Abstract: Conclusion: At the time of birth, the incudo-mallear joint is completely developed. OBJECTIVE. To study the development of the incudo-mallear joint in human embryos and fetuses. MATERIALS AND METHODS. In all, 46 temporal bones with ages between 9 mm and ...

    Abstract Conclusion: At the time of birth, the incudo-mallear joint is completely developed. OBJECTIVE. To study the development of the incudo-mallear joint in human embryos and fetuses. MATERIALS AND METHODS. In all, 46 temporal bones with ages between 9 mm and newborns were studied. The preparations were cut in a series and dyed using Martins' trichrome technique. RESULTS. The incudo-mallear joint acquires the characteristics of a saddle joint at 10 weeks of development. The cartilage that covers the articular surfaces is formed by different strata that develop successively: the superficial stratum at 14 weeks, the transitional between 15 and 19 weeks, and the radial from 20 weeks. The subchondral bone develops between weeks 25 and 28 by the mechanisms of apposition and extension of the periosteal and endosteal bones, but it is not until week 30 that it completely covers the articular surfaces, consisting of bone fascicles whereby the lines of force will be transmitted. The articular capsule is formed as from the inter-zone. The surface zone develops the capsular ligament, and the internal surface develops the synovial membrane. Even though it is not consistent, the primordium of the meniscus is seen at 18 weeks.
    MeSH term(s) Bone and Bones/embryology ; Cartilage, Articular/embryology ; Humans ; Incus/embryology ; Ligaments, Articular/embryology ; Malleus/embryology ; Synovial Membrane/embryology
    Language English
    Publishing date 2009-12
    Publishing country England
    Document type Journal Article
    ISSN 1651-2251
    ISSN (online) 1651-2251
    DOI 10.3109/00016480902849435
    Database MEDical Literature Analysis and Retrieval System OnLINE

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