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  1. Book ; Online ; E-Book: Seizures in critical care

    Varelas, Panayiotis / Claassen, Jan

    a guide to diagnosis and therapeutics

    (Current clinical neurology)

    2017  

    Author's details Panayiotis Varelas, Jan Claasen editors
    Series title Current clinical neurology
    Keywords critical care ; emergency medicine ; neurology ; neurosurgery ; seizures
    Subject code 610
    Language English
    Size 1 Online-Ressource (xii, 377 Seiten), Illustrationen
    Edition Third edition
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Note Lizenzpflichtig
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019408737
    ISBN 978-3-319-49557-6 ; 9783319495552 ; 3-319-49557-7 ; 3319495550
    DOI 10.1007/978-3-319-49557-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Beyond crystal balls: multimodal prediction of early recovery of consciousness.

    Claassen, Jan

    Brain : a journal of neurology

    2022  Volume 146, Issue 1, Page(s) 6–7

    MeSH term(s) Humans ; Consciousness ; Intensive Care Units
    Language English
    Publishing date 2022-12-16
    Publishing country England
    Document type Editorial ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 80072-7
    ISSN 1460-2156 ; 0006-8950
    ISSN (online) 1460-2156
    ISSN 0006-8950
    DOI 10.1093/brain/awac434
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Book: Plum and Posner's diagnosis and treatment of stupor and coma

    Posner, Jerome B. / Saper, Clifford B. / Schiff, Nicholas D. / Claassen, Jan

    (Contemporary neurology series ; 93)

    2019  

    Title variant Diagnosis and treatment of stupor and coma
    Author's details [edited by] Jerome B. Posner, Clifford B. Saper, Nicholas D. Schiff, Jan Claassen
    Series title Contemporary neurology series ; 93
    Collection
    Keywords Coma / diagnosis ; Stupor / diagnosis ; Brain Diseases / diagnosis ; Brain Injuries / diagnosis
    Language English
    Size xi, 502 Seiten, Illustrationen
    Edition Fifth edition
    Publisher Oxford University Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT020354291
    ISBN 978-0-19-020887-5 ; 9780190208882 ; 9780190208899 ; 9780190208905 ; 0-19-020887-2 ; 0190208880 ; 0190208899 ; 0190208902
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    2020 A 200 available for loan (reading room) Lesesaal EG
    2020 A 295 available for loan (reading room) Lesesaal EG

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  4. Article ; Online: Convexity subarachnoid haemorrhage - Authors' reply.

    Claassen, Jan / Park, Soojin

    Lancet (London, England)

    2023  Volume 401, Issue 10372, Page(s) 194

    MeSH term(s) Humans ; Subarachnoid Hemorrhage/diagnostic imaging ; Subarachnoid Hemorrhage/etiology
    Language English
    Publishing date 2023-01-20
    Publishing country England
    Document type Letter ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(23)00007-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Coma science: intensive care as the new frontier.

    Claassen, Jan

    Intensive care medicine

    2019  Volume 46, Issue 1, Page(s) 97–101

    MeSH term(s) Coma/physiopathology ; Coma/therapy ; Humans ; Intensive Care Units/organization & administration ; Intensive Care Units/trends
    Language English
    Publishing date 2019-11-20
    Publishing country United States
    Document type Editorial
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-019-05820-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Brain Oxygen Monitoring and the Potential for Precision Medicine for Acutely Brain-Injured Patients.

    Claassen, Jan

    Neurocritical care

    2019  Volume 31, Issue 2, Page(s) 247–248

    MeSH term(s) Brain ; Brain Injuries ; Humans ; Oxygen ; Precision Medicine ; Subarachnoid Hemorrhage
    Chemical Substances Oxygen (S88TT14065)
    Language English
    Publishing date 2019-06-13
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2381896-7
    ISSN 1556-0961 ; 1541-6933
    ISSN (online) 1556-0961
    ISSN 1541-6933
    DOI 10.1007/s12028-019-00757-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Common data elements for disorders of consciousness.

    Edlow, Brian L / Claassen, Jan / Suarez, Jose I

    Neurocritical care

    2024  Volume 40, Issue 2, Page(s) 715–717

    MeSH term(s) Humans ; Common Data Elements ; Consciousness Disorders/diagnosis ; Consciousness Disorders/etiology ; Consciousness
    Language English
    Publishing date 2024-01-31
    Publishing country United States
    Document type Editorial
    ZDB-ID 2381896-7
    ISSN 1556-0961 ; 1541-6933
    ISSN (online) 1556-0961
    ISSN 1541-6933
    DOI 10.1007/s12028-023-01931-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Spontaneous subarachnoid haemorrhage.

    Claassen, Jan / Park, Soojin

    Lancet (London, England)

    2022  Volume 400, Issue 10355, Page(s) 846–862

    Abstract: Subarachnoid haemorrhage (SAH) is the third most common subtype of stroke. Incidence has decreased over past decades, possibly in part related to lifestyle changes such as smoking cessation and management of hypertension. Approximately a quarter of ... ...

    Abstract Subarachnoid haemorrhage (SAH) is the third most common subtype of stroke. Incidence has decreased over past decades, possibly in part related to lifestyle changes such as smoking cessation and management of hypertension. Approximately a quarter of patients with SAH die before hospital admission; overall outcomes are improved in those admitted to hospital, but with elevated risk of long-term neuropsychiatric sequelae such as depression. The disease continues to have a major public health impact as the mean age of onset is in the mid-fifties, leading to many years of reduced quality of life. The clinical presentation varies, but severe, sudden onset of headache is the most common symptom, variably associated with meningismus, transient or prolonged unconsciousness, and focal neurological deficits including cranial nerve palsies and paresis. Diagnosis is made by CT scan of the head possibly followed by lumbar puncture. Aneurysms are commonly the underlying vascular cause of spontaneous SAH and are diagnosed by angiography. Emergent therapeutic interventions are focused on decreasing the risk of rebleeding (ie, preventing hypertension and correcting coagulopathies) and, most crucially, early aneurysm treatment using coil embolisation or clipping. Management of the disease is best delivered in specialised intensive care units and high-volume centres by a multidisciplinary team. Increasingly, early brain injury presenting as global cerebral oedema is recognised as a potential treatment target but, currently, disease management is largely focused on addressing secondary complications such as hydrocephalus, delayed cerebral ischaemia related to microvascular dysfunction and large vessel vasospasm, and medical complications such as stunned myocardium and hospital acquired infections.
    MeSH term(s) Brain Ischemia/complications ; Humans ; Hypertension/complications ; Intracranial Aneurysm/complications ; Quality of Life ; Subarachnoid Hemorrhage/diagnosis ; Subarachnoid Hemorrhage/etiology ; Subarachnoid Hemorrhage/therapy
    Language English
    Publishing date 2022-08-16
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(22)00938-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Validation of prognostic stroke scores - comments on "Evaluation of FRESH scores in predicting outcome and quality of life after aneurysmal subarachnoid haemorrhage in a European patient cohort".

    Witsch, Jens / Sloane, Kelly L / Rothstein, Aaron / Claassen, Jan

    Acta neurochirurgica

    2024  Volume 166, Issue 1, Page(s) 156

    MeSH term(s) Humans ; Subarachnoid Hemorrhage/diagnosis ; Prognosis ; Quality of Life ; Stroke ; Glasgow Outcome Scale
    Language English
    Publishing date 2024-03-28
    Publishing country Austria
    Document type Letter ; Comment
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-024-06046-6
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  10. Article ; Online: The Electrographic Effects of Ketamine on Patients With Refractory Status Epilepticus After Cardiac Arrest: A Single-Center Retrospective Cohort.

    Qing, Kurt / Alkhachroum, Ayham / Claassen, Jan / Forgacs, Peter / Schiff, Nicholas

    Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society

    2024  

    Abstract: Purpose: To investigate the effects of ketamine on patients with refractory status epilepticus after cardiac arrest.: Methods: In this retrospective cohort, selected EEG segments from patients after cardiac arrest were classified into different EEG ... ...

    Abstract Purpose: To investigate the effects of ketamine on patients with refractory status epilepticus after cardiac arrest.
    Methods: In this retrospective cohort, selected EEG segments from patients after cardiac arrest were classified into different EEG patterns (based on background continuity and burden of epileptiform discharges) and spectral profiles (based on the presence of frequency components). For patients who received ketamine, EEG data were compared before, during, and after ketamine infusion; for the no-ketamine group, EEG data were compared at three separated time points during recording. Ketamine usage was determined by clinical providers. Electrographic improvement in epileptiform activity was scored, and the odds ratio was calculated using the Fisher exact test. Functional outcome measures at time of discharge were also examined.
    Results: Of a total of 38 patients with postcardiac arrest refractory status epilepticus, 13 received ketamine and 25 did not. All patients were on ≥2 antiseizure medications including at least one sedative infusion (midazolam). For the ketamine group, eight patients had electrographic improvement, compared with only two patients in the no-ketamine group, with an odds ratio of 7.19 (95% confidence interval 1.16-44.65, P value of 0.0341) for ketamine versus no ketamine. Most of the patients who received ketamine had myoclonic status epilepticus, and overall neurologic outcomes were poor with no patients having a favorable outcome.
    Conclusions: For postarrest refractory status epilepticus, ketamine use was associated with electrographic improvement, but with the available data, it is unclear whether ketamine use or EEG improvement can be linked to better functional recovery.
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605640-4
    ISSN 1537-1603 ; 0736-0258
    ISSN (online) 1537-1603
    ISSN 0736-0258
    DOI 10.1097/WNP.0000000000001065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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