LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 352

Search options

  1. Article: Local Physicians, PSRO's and HSA's.

    Clark, A G

    The Western journal of medicine

    2008  Volume 128, Issue 6, Page(s) 548

    Language English
    Publishing date 2008-08-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 189235-6
    ISSN 1476-2978 ; 0093-0415 ; 0008-1264
    ISSN (online) 1476-2978
    ISSN 0093-0415 ; 0008-1264
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 168: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Non-conflict theories for the evolution of genomic imprinting.

    Spencer, H G / Clark, A G

    Heredity

    2014  Volume 113, Issue 2, Page(s) 112–118

    Abstract: Theories focused on kinship and the genetic conflict it induces are widely considered to be the primary explanations for the evolution of genomic imprinting. However, there have appeared many competing ideas that do not involve kinship/conflict. These ... ...

    Abstract Theories focused on kinship and the genetic conflict it induces are widely considered to be the primary explanations for the evolution of genomic imprinting. However, there have appeared many competing ideas that do not involve kinship/conflict. These ideas are often overlooked because kinship/conflict is entrenched in the literature, especially outside evolutionary biology. Here we provide a critical overview of these non-conflict theories, providing an accessible perspective into this literature. We suggest that some of these alternative hypotheses may, in fact, provide tenable explanations of the evolution of imprinting for at least some loci.
    MeSH term(s) Adaptation, Biological ; Animals ; Biological Evolution ; Female ; Genomic Imprinting ; Humans ; Male ; Models, Genetic ; Selection, Genetic
    Language English
    Publishing date 2014-01-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2423-5
    ISSN 1365-2540 ; 0018-067X
    ISSN (online) 1365-2540
    ISSN 0018-067X
    DOI 10.1038/hdy.2013.129
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ub I Zs.154: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Sex-ratio meiotic drive and interspecific competition.

    Unckless, R L / Clark, A G

    Journal of evolutionary biology

    2014  Volume 27, Issue 8, Page(s) 1513–1521

    Abstract: It has long been known that processes occurring within a species may impact the interactions between species. For example, as competitive ability is sensitive to parameters including reproductive rate, carrying capacity and competition efficiency, the ... ...

    Abstract It has long been known that processes occurring within a species may impact the interactions between species. For example, as competitive ability is sensitive to parameters including reproductive rate, carrying capacity and competition efficiency, the outcome of interspecific competition may be influenced by any process that alters these attributes. Although several such scenarios have been discussed, the influence of selfish genetic elements within one species on competition between species has not received theoretical treatment. We show that, with strong competition, sex-ratio meiotic drive systems can result in a significant shift in community composition because the effective birth rate in the population may be increased by a female-biased sex ratio. Using empirical data, we attempt to estimate the magnitude of this effect in several Drosophila species. We infer that meiotic drive elements, selfish genetic elements within species, can provide a substantial competitive advantage to that species within a community.
    MeSH term(s) Animals ; Biota/physiology ; Competitive Behavior/physiology ; Computer Simulation ; Drosophila/physiology ; Female ; Inheritance Patterns/physiology ; Male ; Meiosis/physiology ; Models, Biological ; Repetitive Sequences, Nucleic Acid/genetics ; Sex Ratio ; Species Specificity
    Language English
    Publishing date 2014-05-19
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 1465318-7
    ISSN 1420-9101 ; 1010-061X
    ISSN (online) 1420-9101
    ISSN 1010-061X
    DOI 10.1111/jeb.12411
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: Using next-generation RNA sequencing to identify imprinted genes.

    Wang, X / Clark, A G

    Heredity

    2014  Volume 113, Issue 2, Page(s) 156–166

    Abstract: Genomic imprinting is manifested as differential allelic expression (DAE) depending on the parent-of-origin. The most direct way to identify imprinted genes is to directly score the DAE in a context where one can identify which parent transmitted each ... ...

    Abstract Genomic imprinting is manifested as differential allelic expression (DAE) depending on the parent-of-origin. The most direct way to identify imprinted genes is to directly score the DAE in a context where one can identify which parent transmitted each allele. Because many genes display DAE, simply scoring DAE in an individual is not sufficient to identify imprinted genes. In this paper, we outline many technical aspects of a scheme for identification of imprinted genes that makes use of RNA sequencing (RNA-seq) from tissues isolated from F1 offspring derived from the pair of reciprocal crosses. Ideally, the parental lines are from two inbred strains that are not closely related to each other. Aspects of tissue purity, RNA extraction, library preparation and bioinformatic inference of imprinting are all covered. These methods have already been applied in a number of organisms, and one of the most striking results is the evolutionary fluidity with which novel imprinted genes are gained and lost within genomes. The general methodology is also applicable to a wide range of other biological problems that require quantification of allele-specific expression using RNA-seq, such as cis-regulation of gene expression, X chromosome inactivation and random monoallelic expression.
    MeSH term(s) Alleles ; Animals ; Animals, Inbred Strains ; Computational Biology/methods ; Crosses, Genetic ; Female ; Gene Expression Profiling ; Gene Expression Regulation ; Gene Library ; Genomic Imprinting ; Genomics/methods ; High-Throughput Nucleotide Sequencing ; Humans ; Male ; Polymorphism, Single Nucleotide ; Sequence Analysis, RNA
    Language English
    Publishing date 2014-03-12
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 2423-5
    ISSN 1365-2540 ; 0018-067X
    ISSN (online) 1365-2540
    ISSN 0018-067X
    DOI 10.1038/hdy.2014.18
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ub I Zs.154: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: Estimation of linkage in the presence of multiplicative viability effects.

    Clark, A G

    Genetics

    2007  Volume 99, Issue 1, Page(s) 157–168

    Abstract: Log-linear analysis of contingency tables is applied to trihybrid backcross data to estimate linkage and viability. Whereas nonadditive viability differences perturb recombination estimates in the classical analysis, this statistical procedure yields ... ...

    Abstract Log-linear analysis of contingency tables is applied to trihybrid backcross data to estimate linkage and viability. Whereas nonadditive viability differences perturb recombination estimates in the classical analysis, this statistical procedure yields maximum likelihood crossover frequency estimates in the presence of multiplicative viability effects. Other advantages of this method include: (1) estimation of viability effects of gene substitution at each locus, (2) estimation of asymptotic confidence intervals on recombination frequencies and viabilities, and (3) it tests the null hypothesis of no interference and no viability interactions. Extensions to cover more loci and to allow certain kinds of epistasis are easily made. Relative merits of the proposed and classical methods are discussed.
    Language English
    Publishing date 2007-01-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2167-2
    ISSN 1943-2631 ; 0016-6731
    ISSN (online) 1943-2631
    ISSN 0016-6731
    DOI 10.1093/genetics/99.1.157
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 767: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article: A comparison of methods of treatment of extensive burns at the San Francisco General Hospital.

    CLARK, A G

    American journal of surgery

    2003  Volume 102, Page(s) 231–239

    MeSH term(s) Burns/therapy ; Hospitals, General ; Humans ; San Francisco
    Language English
    Publishing date 2003-04-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2953-1
    ISSN 1879-1883 ; 0002-9610
    ISSN (online) 1879-1883
    ISSN 0002-9610
    DOI 10.1016/0002-9610(61)90389-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.42: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article: Sex‐ratio meiotic drive and interspecific competition

    Unckless, R. L / Clark, A. G

    Journal of evolutionary biology. 2014 Aug., v. 27, no. 8

    2014  

    Abstract: It has long been known that processes occurring within a species may impact the interactions between species. For example, as competitive ability is sensitive to parameters including reproductive rate, carrying capacity and competition efficiency, the ... ...

    Abstract It has long been known that processes occurring within a species may impact the interactions between species. For example, as competitive ability is sensitive to parameters including reproductive rate, carrying capacity and competition efficiency, the outcome of interspecific competition may be influenced by any process that alters these attributes. Although several such scenarios have been discussed, the influence of selfish genetic elements within one species on competition between species has not received theoretical treatment. We show that, with strong competition, sex‐ratio meiotic drive systems can result in a significant shift in community composition because the effective birth rate in the population may be increased by a female‐biased sex ratio. Using empirical data, we attempt to estimate the magnitude of this effect in several Drosophila species. We infer that meiotic drive elements, selfish genetic elements within species, can provide a substantial competitive advantage to that species within a community.
    Keywords Drosophila ; birth rate ; carrying capacity ; community structure ; interspecific competition ; meiotic drive ; sex ratio
    Language English
    Dates of publication 2014-08
    Size p. 1513-1521.
    Publishing place Blackwell Science
    Document type Article
    ZDB-ID 1465318-7
    ISSN 1420-9101 ; 1010-061X
    ISSN (online) 1420-9101
    ISSN 1010-061X
    DOI 10.1111/jeb.12411
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article: Sperm competition and the maintenance of polymorphism.

    Clark, A G

    Heredity

    2002  Volume 88, Issue 2, Page(s) 148–153

    Abstract: Sperm competition may occur whenever sperm from more than one male are present in the reproductive tract of the female. Studies of field-caught Drosophila reveal that a substantial fraction (80%) of females clearly have sperm from more than one male, and ...

    Abstract Sperm competition may occur whenever sperm from more than one male are present in the reproductive tract of the female. Studies of field-caught Drosophila reveal that a substantial fraction (80%) of females clearly have sperm from more than one male, and the figure is probably higher because only a small number of progeny are typically surveyed, so a strong skew in paternity can make multiply-mated females appear as singly mated unless appropriate models are applied. Examination of genetic variation in aspects of sperm competition has revealed some striking patterns, particularly in the implications for the maintenance of polymorphism. The magnitude of variation in sperm competitive ability is as great as that for other fitness components, and the males with the strongest displacement also appear to be the ones with the greatest positive effect on fertility. Why then does not the most competitive allele simply go to fixation? Such synergistic pleiotropy makes the polymorphism even more unexpected. Examination of patterns of competitive success of pairs of male genotypes, and of female-male interactions, demonstrate clearly that the outcome of sperm competition is not a simple property of each male. That is, sperm competitive ability of male genotypes cannot simply be ranked from best to worst. Rather, the outcome of each competitive bout depends on the particular pair of males. These results have intriguing implications for the molecular biology of genes involved in the determination of sperm competitive success, and on the opportunity for maintenance of polymorphism in those genes.
    MeSH term(s) Animals ; Drosophila/physiology ; Female ; Fertility/genetics ; Fertility/physiology ; Genetic Variation ; Male ; Sexual Behavior, Animal/physiology ; Spermatozoa/physiology
    Language English
    Publishing date 2002-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2423-5
    ISSN 1365-2540 ; 0018-067X
    ISSN (online) 1365-2540
    ISSN 0018-067X
    DOI 10.1038/sj.hdy.6800019
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ub I Zs.154: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article: The search for meaning in noncoding DNA.

    Clark, A G

    Genome research

    2001  Volume 11, Issue 8, Page(s) 1319–1320

    MeSH term(s) Animals ; Codon/genetics ; Conserved Sequence ; DNA/genetics ; DNA, Intergenic/genetics ; Drosophila/genetics ; Evolution, Molecular ; Introns/genetics ; Untranslated Regions/genetics
    Chemical Substances Codon ; DNA, Intergenic ; Untranslated Regions ; DNA (9007-49-2)
    Language English
    Publishing date 2001-08
    Publishing country United States
    Document type Comment ; Journal Article
    ZDB-ID 1284872-4
    ISSN 1549-5469 ; 1088-9051 ; 1054-9803
    ISSN (online) 1549-5469
    ISSN 1088-9051 ; 1054-9803
    DOI 10.1101/gr.201601
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 3729: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 8: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article ; Online: The influence of open-top chambers on the growth and development of field bean.

    Sanders, G E / Clark, A G / Colls, J J

    The New phytologist

    2013  Volume 117, Issue 3, Page(s) 439–447

    Abstract: In 1988, open-top chambers (OTCs) based on the Raleigh (USA) design were used to investigate the effect of ambient pollutants on field-sown Vicia faba cv, Ticol. This paper reports an aspect of this study in which the effect of the chamber itself on crop ...

    Abstract In 1988, open-top chambers (OTCs) based on the Raleigh (USA) design were used to investigate the effect of ambient pollutants on field-sown Vicia faba cv, Ticol. This paper reports an aspect of this study in which the effect of the chamber itself on crop growth and development was investigated. Non-filtered chamber (NF OTC) microclimates were typically 0.8°C warmer, with 20% less radiation and reduced wind speeds compared with open-field sub-plots (AA treatments). These differences are sufficient to induce alterations in the growth and development of V. faba. Plant development progressed more quickly inside the chambers in response to the faster accumulation of thermal time. Chamber-grown V. faba were up to 20 cm taller and had fewer branches (0.7 compared with 1.2 per plant) than plants grown in the AA treatments. Larger leaf areas developed on the NF plants, and there were fewer stomata per unit leaf area in this treatment (34 compared with 42 mm
    Language English
    Publishing date 2013-08-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 208885-x
    ISSN 1469-8137 ; 0028-646X
    ISSN (online) 1469-8137
    ISSN 0028-646X
    DOI 10.1111/j.1469-8137.1991.tb00008.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 868: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top