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  1. Book: Oxford textbook of heart failure

    Clark, Andrew L. / Gardner, Roy S. / McDonagh, Theresa A.

    (Oxford textbooks in cardiology)

    2022  

    Title variant Textbook of heart failure ; Heart failure
    Author's details edited by Andrew Clark, Roy Gardner, Theresa McDonagh
    Series title Oxford textbooks in cardiology
    Keywords Heart failure ; Akutes Herzversagen
    Subject code 616.129
    Language English
    Size xv, 873 Seiten, Illustrationen, 28 cm
    Edition Second edition
    Publisher Oxford University Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT021370118
    ISBN 978-0-19-876622-3 ; 0-19-876622-X
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2022 A 641 available for loan (reading room) Lesesaal EG

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  2. Article ; Online: Diuretic Treatment in Patients with Heart Failure: Current Evidence and Future Directions - Part I: Loop Diuretics.

    Cuthbert, Joseph James / Clark, Andrew L

    Current heart failure reports

    2024  Volume 21, Issue 2, Page(s) 101–114

    Abstract: Purpose of review: Fluid retention or congestion is a major cause of symptoms, poor quality of life, and adverse outcome in patients with heart failure (HF). Despite advances in disease-modifying therapy, the mainstay of treatment for congestion-loop ... ...

    Abstract Purpose of review: Fluid retention or congestion is a major cause of symptoms, poor quality of life, and adverse outcome in patients with heart failure (HF). Despite advances in disease-modifying therapy, the mainstay of treatment for congestion-loop diuretics-has remained largely unchanged for 50 years. In these two articles (part I: loop diuretics and part II: combination therapy), we will review the history of diuretic treatment and the current trial evidence for different diuretic strategies and explore potential future directions of research.
    Recent findings: We will assess recent trials including DOSE, TRANSFORM, ADVOR, CLOROTIC, OSPREY-AHF, and PUSH-AHF amongst others, and assess how these may influence current practice and future research. There are few data on which to base diuretic therapy in clinical practice. The most robust evidence is for high dose loop diuretic treatment over low-dose treatment for patients admitted to hospital with HF, yet this is not reflected in guidelines. There is an urgent need for more and better research on different diuretic strategies in patients with HF.
    MeSH term(s) Humans ; Heart Failure/drug therapy ; Sodium Potassium Chloride Symporter Inhibitors/therapeutic use ; Quality of Life ; Diuretics/therapeutic use ; Hospitalization
    Chemical Substances Sodium Potassium Chloride Symporter Inhibitors ; Diuretics
    Language English
    Publishing date 2024-01-19
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2151202-4
    ISSN 1546-9549 ; 1546-9530
    ISSN (online) 1546-9549
    ISSN 1546-9530
    DOI 10.1007/s11897-024-00643-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5936: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  3. Book: Heart failure

    Clark, Andrew L.

    diagnosis and management

    2001  

    Author's details ed. by Andrew L. Clark
    Keywords Akutes Herzversagen
    Language English
    Size X, 214 S. : Ill., graph. Darst.
    Publisher Dunitz
    Publishing place London u.a.
    Publishing country Great Britain
    Document type Book
    HBZ-ID HT012960538
    ISBN 1-85317-717-2 ; 978-1-85317-717-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2001 A 1667 order for loan Magazin

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  4. Article: Optimal Management of Heart Failure and Chronic Obstructive Pulmonary Disease: Clinical Challenges.

    Cuthbert, Joseph J / Pellicori, Pierpaolo / Clark, Andrew L

    International journal of general medicine

    2022  Volume 15, Page(s) 7961–7975

    Abstract: Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are common causes of breathlessness which frequently co-exist; one potentially exacerbating the other. Distinguishing between the two can be challenging due to their similar ... ...

    Abstract Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are common causes of breathlessness which frequently co-exist; one potentially exacerbating the other. Distinguishing between the two can be challenging due to their similar symptomatology and overlapping risk factors, but a timely and correct diagnosis is potentially lifesaving. Modern treatment for HF can substantially improve symptoms and prognosis for many patients and may have beneficial effects for patients with COPD. Conversely, while many inhaled treatments for COPD can improve symptoms and reduce exacerbations, there is conflicting evidence regarding the safety of some inhaled treatments for COPD in patients with HF. Here we explore the overlap between HF and COPD, examine the effect of one condition on the other, and address the challenges of managing patients with both conditions.
    Language English
    Publishing date 2022-10-25
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2452220-X
    ISSN 1178-7074
    ISSN 1178-7074
    DOI 10.2147/IJGM.S295467
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Chronic Obstructive Pulmonary Disease and Heart Failure: A Breathless Conspiracy.

    Pellicori, Pierpaolo / Cleland, John G F / Clark, Andrew L

    Cardiology clinics

    2022  Volume 40, Issue 2, Page(s) 171–182

    Abstract: Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are both common causes of breathlessness and often conspire to confound accurate diagnosis and optimal therapy. Risk factors (such as aging, smoking, and obesity) and clinical ... ...

    Abstract Heart failure (HF) and chronic obstructive pulmonary disease (COPD) are both common causes of breathlessness and often conspire to confound accurate diagnosis and optimal therapy. Risk factors (such as aging, smoking, and obesity) and clinical presentation (eg, cough and breathlessness on exertion) can be very similar, but the treatment and prognostic implications are very different. This review discusses the diagnostic challenges in individuals with exertional dyspnea. We also highlight the prevalence, clinical relevance and therapeutic implications of a concurrent diagnosis of COPD and HF.
    MeSH term(s) Dyspnea/etiology ; Heart Failure/complications ; Heart Failure/diagnosis ; Heart Failure/epidemiology ; Humans ; Prevalence ; Pulmonary Disease, Chronic Obstructive/complications ; Pulmonary Disease, Chronic Obstructive/diagnosis ; Pulmonary Disease, Chronic Obstructive/epidemiology ; Risk Factors
    Language English
    Publishing date 2022-03-31
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1196385-2
    ISSN 1558-2264 ; 0733-8651
    ISSN (online) 1558-2264
    ISSN 0733-8651
    DOI 10.1016/j.ccl.2021.12.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Se 853: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Treating sarcopenia: the LACE trial.

    Clark, Andrew L / Abel, Alexandra A I

    Journal of cachexia, sarcopenia and muscle

    2022  Volume 13, Issue 3, Page(s) 1437–1439

    MeSH term(s) Clinical Trials as Topic ; Humans ; Sarcopenia/therapy
    Language English
    Publishing date 2022-04-19
    Publishing country Germany
    Document type Editorial
    ZDB-ID 2586864-0
    ISSN 2190-6009 ; 2190-5991
    ISSN (online) 2190-6009
    ISSN 2190-5991
    DOI 10.1002/jcsm.13004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Long-Term Pharmacological Management of Reduced Ejection Fraction Following Acute Myocardial Infarction: Current Status and Future Prospects.

    Abel, Alexandra A I / Clark, Andrew L

    International journal of general medicine

    2021  Volume 14, Page(s) 7797–7805

    Abstract: Heart failure (HF) with reduced ejection fraction is common following acute myocardial infarction (MI), and active medical management can have a profound impact on prognosis. Reviewing relevant clinical trials, we focus on the pharmacological management ... ...

    Abstract Heart failure (HF) with reduced ejection fraction is common following acute myocardial infarction (MI), and active medical management can have a profound impact on prognosis. Reviewing relevant clinical trials, we focus on the pharmacological management of left ventricular systolic dysfunction (LVSD) following an acute MI, although there is overlap with the pharmacological management of chronic HF due to reduced ejection fraction. Angiotensin converting enzyme (ACE) inhibitors, beta-blockers, and mineralocorticoid receptor antagonists are the mainstay of medical management in patients with LVSD post MI; there may also be a role for anticoagulation. Sacubitril-valsartan (angiotensin receptor neprilysin inhibitor) has not yet been shown to be superior to an ACE inhibitor in reducing cardiovascular mortality and HF events in patients with LVSD post MI. Large randomised trials evaluating sodium glucose transporter 2 (SGLT-2) inhibitors in LVSD post MI are ongoing.
    Language English
    Publishing date 2021-11-08
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2452220-X
    ISSN 1178-7074
    ISSN 1178-7074
    DOI 10.2147/IJGM.S294896
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Impact of Malnutrition Using Geriatric Nutritional Risk Index in Heart Failure With Preserved Ejection Fraction.

    Clark, Andrew L / Sze, Shirley

    JACC. Heart failure

    2019  Volume 7, Issue 8, Page(s) 676–677

    MeSH term(s) Aged ; Heart Failure ; Humans ; Malnutrition ; Nutrition Assessment ; Stroke Volume ; Ventricular Function, Left
    Language English
    Publishing date 2019-07-10
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2705621-1
    ISSN 2213-1787 ; 2213-1779
    ISSN (online) 2213-1787
    ISSN 2213-1779
    DOI 10.1016/j.jchf.2019.06.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Outcomes in patients treated with loop diuretics without a diagnosis of heart failure: a retrospective cohort study.

    Cuthbert, Joseph James / Soyiri, Ireneous / Lomax, Stephanie Jayne / Turgoose, John / Fuat, Ahmet / Cohen, Judith / Clark, Andrew L

    Heart (British Cardiac Society)

    2024  

    Abstract: Background: Loop diuretics are commonly prescribed in the community, not always to patients with a recorded diagnosis of heart failure (HF). The rate of HF events in patients prescribed loop diuretics without a diagnosis of HF is unknown.: Methods: ... ...

    Abstract Background: Loop diuretics are commonly prescribed in the community, not always to patients with a recorded diagnosis of heart failure (HF). The rate of HF events in patients prescribed loop diuretics without a diagnosis of HF is unknown.
    Methods: This was a propensity-matched cohort study using data from the Clinical Practice Research Datalink, Hospital Episode Statistics and Office of National Statistics in the UK. Patients prescribed a loop diuretic without a diagnosis of HF (loop diuretic group) between 1 January 2010 and 31 December 2015 were compared with patients with HF (HF group)-analysis A, and patients with risk factors for HF (either ischaemic heart disease, or diabetes
    Results: From a total population of 180 384 patients (78 968 in the loop diuretic group, 28 177 in the HF group and 73 239 in the at-risk group), there were 59 694 patients, 22 352 patients and 57 219 patients in the loop diuretic, HF and at-risk groups, respectively, after exclusion criteria were applied. After propensity matching for age, sex and comorbidities, patients in the loop diuretic group had a similar rate of HF events as those in the HF group (71.9% vs 72.1%; HR=0.92 (95% CI 0.90 to 0.94); p<0.001), and twice as those in the at-risk group (59.2% vs 35.7%; HR=2.04 (95% CI 2.00 to 2.08); p<0.001).
    Conclusions: Patients prescribed a loop diuretic without a recorded diagnosis of HF experience HF events at a rate comparable with that of patients
    Language English
    Publishing date 2024-04-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 1303417-0
    ISSN 1468-201X ; 1355-6037
    ISSN (online) 1468-201X
    ISSN 1355-6037
    DOI 10.1136/heartjnl-2023-323577
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui IV Zs.40: Show issues Location:
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    Zs.MO 112: Show issues

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  10. Article ; Online: Almanac 2013: heart failure.

    Clark, Andrew L

    Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology

    2014  Volume 14, Issue 3, Page(s) 313–318

    MeSH term(s) Databases, Factual ; England ; Heart Failure/therapy ; Humans ; Medical Audit ; Practice Guidelines as Topic ; Wales
    Language English
    Publishing date 2014-05
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 2278670-3
    ISSN 1308-0032 ; 1302-8723
    ISSN (online) 1308-0032
    ISSN 1302-8723
    DOI 10.5152/akd.2014.119612014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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