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  1. Article ; Online: Biothérapies dans l’asthme sévère de l’enfant.

    Bouderbala, Yanis / Clark, Évangéline / Tabardel, Marion / Demoly, Pascal / Caimmi, Davide

    La Revue du praticien

    2023  Volume 73, Issue 7, Page(s) 703–707

    Abstract: BIOTHERAPIES IN SEVERE CHILDHOOD ASTHMA. Asthma is a chronic inflammatory disease of the lower airways and is one of the most common chronic conditions during childhood. The management of severe asthmatic patients must be multidisciplinary, personalized, ...

    Title translation Biotherapies in severe childhood asthma.
    Abstract BIOTHERAPIES IN SEVERE CHILDHOOD ASTHMA. Asthma is a chronic inflammatory disease of the lower airways and is one of the most common chronic conditions during childhood. The management of severe asthmatic patients must be multidisciplinary, personalized, and holistic, especially in pediatrics. The therapeutic approach to asthmatic patients has evolved over the last years, targeting inflammatory cells and molecules. Such treatments mainly include biotherapies, and, in children, four monoclonal antibodies are presently available to treat severe asthma: omalizumab, mepolizumab, dupilumab and tezepelumab. These biotherapies have demonstrated short- and medium-term efficacy and safety in both adults and children.
    MeSH term(s) Adult ; Humans ; Child ; Asthma/drug therapy ; Biological Therapy ; Antibodies, Monoclonal/therapeutic use
    Chemical Substances Antibodies, Monoclonal
    Language French
    Publishing date 2023-10-05
    Publishing country France
    Document type English Abstract ; Journal Article
    ZDB-ID 205365-2
    ISSN 2101-017X ; 0035-2640
    ISSN (online) 2101-017X
    ISSN 0035-2640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Editorial comment on "Sensitisation to peach allergen Pru p 7 is associated with severe clinical symptoms in a Spanish population".

    Clark, Evangéline / Giovannini, Mattia / Leung, Agnes Sze Yin / Caimmi, Davide

    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

    2023  Volume 34, Issue 12, Page(s) e14059

    MeSH term(s) Humans ; Prunus persica ; Allergens ; Antigens, Plant ; Plant Proteins ; Food Hypersensitivity/diagnosis
    Chemical Substances Allergens ; Antigens, Plant ; Plant Proteins
    Language English
    Publishing date 2023-12-26
    Publishing country England
    Document type Editorial
    ZDB-ID 1057059-7
    ISSN 1399-3038 ; 0905-6157 ; 0906-5784
    ISSN (online) 1399-3038
    ISSN 0905-6157 ; 0906-5784
    DOI 10.1111/pai.14059
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    Zs.A 3096: Show issues Location:
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  3. Article: Anaphylaxis management in a French pediatric emergency department: Lessons from the ANA-PED study.

    Clark, Evangéline / Kase Tanno, Luciana / Vo, Tram / Blanc, Brigitte / Demoly, Pascal / Caimmi, Davide

    Clinical and translational allergy

    2023  Volume 13, Issue 8, Page(s) e12289

    Abstract: Background: Anaphylaxis is a serious systemic hypersensitivity reaction that requires immediate recognition and prompt administration of epinephrine/adrenaline. The present study aimed to assess the appropriateness of epinephrine/adrenaline use in ... ...

    Abstract Background: Anaphylaxis is a serious systemic hypersensitivity reaction that requires immediate recognition and prompt administration of epinephrine/adrenaline. The present study aimed to assess the appropriateness of epinephrine/adrenaline use in children identified as allergic by physicians in the emergency department (ED) at the time of the reaction, and to identify factors that are possibly associated with epinephrine/adrenaline administration, auto-injector prescription, and further referral to an allergist.
    Methods: We performed a retrospective cross-sectional study at the pediatric ED of the University Hospital of Montpellier, France. We included all consecutive children who attended the ED between 2016 and 2020 with an allergy-related diagnosis at discharge.
    Results: We included 1056 allergy-related visits, including 224 (21.2%) with a diagnosis of anaphylaxis at discharge; only 17.0% of them received an epinephrine/adrenaline injection, and 57.1% consulted an allergist after the acute episode. An auto-injector was prescribed to 63 (28.1%) patients at discharge from the ED. Besides the severity of the clinical presentation, factors associated with a guidelines-based management of the anaphylactic reaction and with an increased administration rate of epinephrine/adrenaline included presence of asthma symptoms and presence of extended skin reactions.
    Conclusions: Our study underlines persistent gaps in the management of pediatric anaphylaxis in ED, focusing on hereby identified levers. By disseminating current knowledge and guidelines on anaphylaxis and allergies, specialists could work together with emergency physicians to establish effective management algorithms and improve anaphylaxis management and care pathways for children experiencing allergic reactions, especially anaphylaxis.
    Trail registration: Clinical Trials, number NCT05112367.
    Language English
    Publishing date 2023-08-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2630865-4
    ISSN 2045-7022
    ISSN 2045-7022
    DOI 10.1002/clt2.12289
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  4. Article ; Online: Allergic contact dermatitis from Cannabis sativa (hemp) seed oil.

    Clark, Evangéline / Nilsson, Ulrika / Samaran, Quentin / Raison-Peyron, Nadia

    Contact dermatitis

    2022  Volume 87, Issue 3, Page(s) 292–293

    MeSH term(s) Cannabis/adverse effects ; Dermatitis, Allergic Contact/diagnosis ; Dermatitis, Allergic Contact/etiology ; Humans ; Plant Oils/adverse effects ; Seeds/adverse effects
    Chemical Substances Plant Oils
    Language English
    Publishing date 2022-05-18
    Publishing country England
    Document type Case Reports
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.14142
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1116: Show issues Location:
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  5. Article ; Online: Efficacy of a Non-Pharmacological Intervention in Seasonal Allergic Rhinitis Symptoms.

    Caimmi, Davide / Clark, Evangéline / Fogel, Paul / Heddebaut, Nicolas / Aubier, Michel / Demoly, Pascal

    International archives of allergy and immunology

    2023  Volume 185, Issue 2, Page(s) 111–115

    Abstract: Background: Patients suffering from allergic rhinitis seek for several therapeutic symptomatic options, including nonconventional treatments, to control their symptoms.: Objectives: Through the present proof-of-concept study, we prospectively ... ...

    Abstract Background: Patients suffering from allergic rhinitis seek for several therapeutic symptomatic options, including nonconventional treatments, to control their symptoms.
    Objectives: Through the present proof-of-concept study, we prospectively investigated the potential role of Puressentiel® nasal protection spray (SNPA) in patients suffering from cypress pollen allergic rhinitis.
    Methods: In 15 adults, we performed two nasal provocation tests, with a cypress pollen extract, with a 15-day interval, with and without previous randomized administration of SNPA, and evaluated a nasal symptom score, the nasal inspiratory peak flow, and the concentration of inflammatory cytokines in the nasal lavage after the procedures.
    Results: Comparing results in patients challenged with and without the SNPA spray before the nasal challenge, we found a 57% mean decrease in symptoms, and a 62% average difference in inspiratory peak flow, after the use of the spray.
    Conclusions: Puressentiel® SNPA is effective in reducing nasal symptoms, as assessed by nasal symptoms score and nasal inspiratory peak flow, and could be a valid natural non-pharmacological option in patients suffering from allergic rhinitis.
    MeSH term(s) Adult ; Humans ; Rhinitis, Allergic, Seasonal/therapy ; Rhinitis, Allergic, Seasonal/drug therapy ; Pollen ; Nose ; Nasal Sprays ; Cytokines ; Administration, Intranasal ; Double-Blind Method
    Chemical Substances Nasal Sprays ; Cytokines
    Language English
    Publishing date 2023-11-03
    Publishing country Switzerland
    Document type News
    ZDB-ID 1108932-5
    ISSN 1423-0097 ; 1018-2438
    ISSN (online) 1423-0097
    ISSN 1018-2438
    DOI 10.1159/000533271
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  6. Article ; Online: PEG-45/dodecyl glycol co-polymer and bis-diglyceryl polyacyladipate-2: Two culprits responsible of an allergic contact dermatitis to a lip balm.

    Clark, Evangéline / Samaran, Quentin / Dereure, Olivier / Raison-Peyron, Nadia

    Contact dermatitis

    2021  Volume 85, Issue 1, Page(s) 117–119

    MeSH term(s) Cosmetics/adverse effects ; Dermatitis, Allergic Contact/etiology ; Humans ; Lip/pathology ; Polyethylene Glycols/adverse effects ; Stearic Acids/adverse effects
    Chemical Substances 12-hydroxy stearic acid ; Cosmetics ; Stearic Acids ; Polyethylene Glycols (3WJQ0SDW1A)
    Language English
    Publishing date 2021-03-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.13811
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  7. Article ; Online: Allergic contact dermatitis to Cupressus sempervirens resin and cross-reaction with colophonium.

    Samaran, Quentin / Clark, Evangeline / Dereure, Olivier / Raison-Peyron, Nadia

    Contact dermatitis

    2020  Volume 83, Issue 1, Page(s) 33–35

    MeSH term(s) Cross Reactions ; Cupressus/adverse effects ; Dermatitis, Allergic Contact/diagnostic imaging ; Dermatitis, Allergic Contact/etiology ; Female ; Humans ; Middle Aged ; Patch Tests ; Resins, Plant/adverse effects
    Chemical Substances Resins, Plant ; rosin (88S87KL877)
    Language English
    Publishing date 2020-04-27
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.13496
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  8. Article ; Online: A new case of spa dermatitis mimicking photo allergy.

    Clark, Evangeline / Samaran, Quentin / Dereure, Olivier / Bourrain, Jean-Luc

    Contact dermatitis

    2020  Volume 83, Issue 1, Page(s) 52–54

    MeSH term(s) Ammonium Sulfate/adverse effects ; Baths/adverse effects ; Dermatitis, Allergic Contact/etiology ; Diagnosis, Differential ; Disinfectants/adverse effects ; Humans ; Male ; Middle Aged ; Patch Tests/methods ; Photosensitivity Disorders/diagnosis
    Chemical Substances Disinfectants ; ammonium peroxydisulfate (22QF6L357F) ; Ammonium Sulfate (SU46BAM238)
    Language English
    Publishing date 2020-03-30
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.13514
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  9. Article ; Online: An immune reaction caused by silicone breast implants.

    Samaran, Quentin / Bekara, Farid / Aljaber, Faisal / Clark, Evangéline / Dereure, Olivier / Raison-Peyron, Nadia

    Contact dermatitis

    2021  Volume 85, Issue 6, Page(s) 703–705

    MeSH term(s) Breast Implants/adverse effects ; Dermatitis, Allergic Contact/diagnosis ; Dermatitis, Allergic Contact/etiology ; Female ; Humans ; Middle Aged ; Prosthesis Failure/adverse effects ; Silicones/adverse effects
    Chemical Substances Silicones
    Language English
    Publishing date 2021-07-23
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.13936
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  10. Article: Clinical review: The suggested management pathway for urticaria in primary care.

    Ryan, Dermot / Tanno, Luciana K / Angier, Elizabeth / Clark, Evangéline / Price, David / Zuberbier, Torsten / Maurer, Marcus

    Clinical and translational allergy

    2022  Volume 12, Issue 10, Page(s) e12195

    Abstract: Background: Urticaria is a common condition presenting both as acute and chronic disease within primary care. To those without specialist training it is poorly understood from the points of view of diagnosis and management. It causes a considerable ... ...

    Abstract Background: Urticaria is a common condition presenting both as acute and chronic disease within primary care. To those without specialist training it is poorly understood from the points of view of diagnosis and management. It causes a considerable disease burden to sufferers with marked impact on quality of life.
    Purpose of this review: The recent publication of the EAACI/GA²LEN/EuroGuiDerm/APAAACI Guideline for the Definition, Classification, Diagnosis and Management of Urticaria guideline prompted us to take this excellent resource and re-configure its findings and recommendations to a non-specialist audience with particular reference to the needs of the primary care team.
    Language English
    Publishing date 2022-10-05
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2630865-4
    ISSN 2045-7022
    ISSN 2045-7022
    DOI 10.1002/clt2.12195
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