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  1. AU="Clark, Nicole F"
  2. AU="Schlemmer, Heinz-Peter"

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  1. Article: Could chlorophyllins improve the safety profile of beta-d-N4-hydroxycytidine versus N-hydroxycytidine, the active ingredient of the SARS-CoV-2 antiviral molnupiravir?

    Clark, Nicole F / Taylor-Robinson, Andrew W / Heimann, Kirsten

    Therapeutic advances in drug safety

    2022  Volume 13, Page(s) 20420986221107753

    Abstract: Could natural plant pigment (chlorophyll) derivatives (chlorophyllins) improve the safety of the antiviral Molnupiravir, used to treat COVID-19 disease? ...

    Abstract Could natural plant pigment (chlorophyll) derivatives (chlorophyllins) improve the safety of the antiviral Molnupiravir, used to treat COVID-19 disease?
    Language English
    Publishing date 2022-07-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2583589-0
    ISSN 2042-0994 ; 2042-0986
    ISSN (online) 2042-0994
    ISSN 2042-0986
    DOI 10.1177/20420986221107753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: An Ecologically Framed Comparison of The Potential for Zoonotic Transmission of Non-Human and Human-Infecting Species of Malaria Parasite.

    Clark, Nicole F / Taylor-Robinson, Andrew W

    The Yale journal of biology and medicine

    2021  Volume 94, Issue 2, Page(s) 361–373

    Abstract: The threats, both real and perceived, surrounding the development of new and emerging infectious diseases of humans are of critical concern to public health and well-being. Among these risks is the potential for zoonotic transmission to humans of species ...

    Abstract The threats, both real and perceived, surrounding the development of new and emerging infectious diseases of humans are of critical concern to public health and well-being. Among these risks is the potential for zoonotic transmission to humans of species of the malaria parasite,
    MeSH term(s) Animals ; Host-Parasite Interactions ; Humans ; Malaria ; Mosquito Vectors ; Parasites ; Plasmodium
    Language English
    Publishing date 2021-06-30
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 200515-3
    ISSN 1551-4056 ; 0044-0086
    ISSN (online) 1551-4056
    ISSN 0044-0086
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: COVID-19 Therapy: Could a Copper Derivative of Chlorophyll

    Clark, Nicole F / Taylor-Robinson, Andrew W

    Frontiers in medicine

    2021  Volume 8, Page(s) 620175

    Language English
    Publishing date 2021-03-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2021.620175
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: COVID-19 Therapy: Could a Chlorophyll Derivative Promote Cellular Accumulation of Zn

    Clark, Nicole F / Taylor-Robinson, Andrew W

    Frontiers in plant science

    2020  Volume 11, Page(s) 1270

    Keywords covid19
    Language English
    Publishing date 2020-08-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2711035-7
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2020.01270
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: COVID-19 Therapy

    Clark, Nicole F. / Taylor-Robinson, Andrew W.

    Frontiers in Plant Science

    Could a Chlorophyll Derivative Promote Cellular Accumulation of Zn2+ Ions to Inhibit SARS-CoV-2 RNA Synthesis?

    2020  Volume 11

    Keywords Plant Science ; covid19
    Publisher Frontiers Media SA
    Publishing country ch
    Document type Article ; Online
    ZDB-ID 2711035-7
    ISSN 1664-462X
    ISSN 1664-462X
    DOI 10.3389/fpls.2020.01270
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: COVID-19 Therapy: Could a Chlorophyll Derivative Promote Cellular Accumulation of Zn 2+Ions to Inhibit SARS-CoV-2 RNA Synthesis?

    Clark, Nicole F. / Taylor-Robinson, Andrew W.

    Front. Plant Sci.

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #760879
    Database COVID19

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  7. Article ; Online: COVID-19 therapy

    Clark, Nicole F / Taylor-Robinson, Andrew W

    Clark, NF, Taylor-Robinson, AW, (2020). COVID-19 therapy: Could a chlorophyll derivative promote cellular accumulation of Zn2+ ions to inhibit SARS-CoV-2 RNA synthesis?. Frontiers in Plant Science, Vol. 11, p. 1-4 http://dx.doi.org/10.3389/fpls.2020.01270

    Could a chlorophyll derivative promote cellular accumulation of Zn2+ ions to inhibit SARS-CoV-2 RNA synthesis?

    2020  

    Abstract: Taylor-Robinson, AW orcid:0000-0001-7342-8348 ... While zinc is known as an antiviral, for which it is taken as a dietary supplement, the therapeutic potential of Zn2+ chlorophyll derivatives to treat viral infections such as SARSCoV-2 has not been ... ...

    Abstract Taylor-Robinson, AW orcid:0000-0001-7342-8348

    While zinc is known as an antiviral, for which it is taken as a dietary supplement, the therapeutic potential of Zn2+ chlorophyll derivatives to treat viral infections such as SARSCoV-2 has not been explored. The rapid uptake of zinc pheophorbide a, a breakdown product of chlorophyll, and consequent release of Zn2+ ions has been shown to have a beneficial therapeutic effect on human adenocarcinoma cell lines through inhibiting viral replication. We propose that a similar approach could be adopted to target SARS-CoV-2-infected lung epithelial cells in vitro. This would pave the way for future clinical therapy to be delivered deep inside human lungs, offering a potential treatment of symptomatic COVID-19 patients.
    Keywords COVID-19 ; SARS-CoV-2 ; RNA synthesis ; Therapy ; Chlorophyll ; Tetrapyrrole ; Zinc pheophorbide ; Cytotoxicity ; 110804 Medical Virology ; 111502 Clinical Pharmacology and Therapeutics ; 110309 Infectious Diseases ; covid19
    Subject code 610
    Publisher Frontiers Media SA
    Publishing country au
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article: Host species of mistletoes (Loranthaceae and Viscaceae) in Australia

    Clark, Nicole F / McComb, Jen A / Taylor-Robinson, Andrew W

    Australian journal of botany. 2020, v. 68, no. 1

    2020  

    Abstract: In order to study the relationships between mistletoes and their host species, comprehensive collections of both mistletoes and hosts are needed. The effect of sampling effort on the estimation of mistletoe host range was demonstrated in a comparison of ... ...

    Abstract In order to study the relationships between mistletoes and their host species, comprehensive collections of both mistletoes and hosts are needed. The effect of sampling effort on the estimation of mistletoe host range was demonstrated in a comparison of an inventory of host mistletoe interactions published by Downey in 1998 and a 2019 inventory presented here, which is based on data from collections in the Australian Virtual Herbarium and information in the literature. New hosts were recorded for 93% of the 90 Australian mistletoes. There were 338 previously known hosts recorded to be parasitised by additional mistletoe species, and 317 new host species that were not previously known as mistletoe hosts (25 being alien species). These were from 78 new host genera and 13 new host families. The total number of host species was 1186 within 327 genera from 92 host families. A total of 63% of all Australian mistletoes parasitise species of either Eucalyptus or Acacia or both these genera. The large rise in host species recorded in less than two decades between inventories suggests that current knowledge of hosts is still incomplete, such that further new hosts will be discovered in future. Some mistletoe species show a strong preference to one host family or genus but due to insufficient collecting it is premature to conclude that any of the three species known from a single host are host specific.
    Keywords Acacia ; Eucalyptus ; Loranthaceae ; Santalaceae ; herbaria ; host range ; hosts ; introduced species ; inventories ; Australia
    Language English
    Size p. 1-13.
    Publishing place CSIRO Publishing
    Document type Article
    Note NAL-AP-2-clean
    ISSN 0067-1924
    DOI 10.1071/BT19137
    Database NAL-Catalogue (AGRICOLA)

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