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  1. Article ; Online: Are Electronic Health Records Sufficiently Accurate to Phenotype Rheumatology Patients With Chronic Pain?

    Clarke, Hance / Fitzcharles, Mary-Ann

    The Journal of rheumatology

    2024  Volume 51, Issue 3, Page(s) 218–220

    MeSH term(s) Humans ; Chronic Pain/diagnosis ; Electronic Health Records ; Rheumatology
    Language English
    Publishing date 2024-03-01
    Publishing country Canada
    Document type Editorial
    ZDB-ID 194928-7
    ISSN 1499-2752 ; 0315-162X
    ISSN (online) 1499-2752
    ISSN 0315-162X
    DOI 10.3899/jrheum.2023-1227
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1168: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 135: Show issues

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  2. Article ; Online: Correction: The role of anesthesiologists in reducing opioid harm.

    Sutherland, Ainsley M / Clarke, Hance A

    Canadian journal of anaesthesia = Journal canadien d'anesthesie

    2022  Volume 70, Issue 2, Page(s) 288

    Title translation Le rôle des anesthésiologistes dans la réduction des préjudices liés aux opioïdes.
    Language English
    Publishing date 2022-09-30
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 91002-8
    ISSN 1496-8975 ; 0832-610X
    ISSN (online) 1496-8975
    ISSN 0832-610X
    DOI 10.1007/s12630-022-02330-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 109: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: The role of anesthesiologists in reducing opioid harm.

    Sutherland, Ainsley M / Clarke, Hance A

    Canadian journal of anaesthesia = Journal canadien d'anesthesie

    2022  Volume 69, Issue 8, Page(s) 917–922

    Title translation Le rôle des anesthésiologistes dans la réduction des préjudices liés aux opioïdes.
    MeSH term(s) Analgesics, Opioid/adverse effects ; Anesthesiologists ; Anesthesiology ; Humans ; Opioid-Related Disorders/epidemiology ; Opioid-Related Disorders/prevention & control
    Chemical Substances Analgesics, Opioid
    Language English
    Publishing date 2022-07-01
    Publishing country United States
    Document type Editorial
    ZDB-ID 91002-8
    ISSN 1496-8975 ; 0832-610X
    ISSN (online) 1496-8975
    ISSN 0832-610X
    DOI 10.1007/s12630-022-02274-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 109: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Cannabinoids dosing for osteoarthritis.

    Miles, Sarah J / Peer, Miki / Ladha, Karim S / Clarke, Hance

    The Lancet regional health. Europe

    2024  Volume 38, Page(s) 100850

    Language English
    Publishing date 2024-01-30
    Publishing country England
    Document type Journal Article
    ISSN 2666-7762
    ISSN (online) 2666-7762
    DOI 10.1016/j.lanepe.2024.100850
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Post-Viral Pain, Fatigue, and Sleep Disturbance Syndromes: Current Knowledge and Future Directions.

    Tackey, Caleb / Slepian, P Maxwell / Clarke, Hance / Mittal, Nimish

    Canadian journal of pain = Revue canadienne de la douleur

    2024  Volume 7, Issue 2, Page(s) 2272999

    Abstract: Background: Post-viral pain syndrome, also known as post-viral syndrome, is a complex condition characterized by persistent pain, fatigue, musculoskeletal pain, neuropathic pain, neurocognitive difficulties, and sleep disturbances that can occur after ... ...

    Abstract Background: Post-viral pain syndrome, also known as post-viral syndrome, is a complex condition characterized by persistent pain, fatigue, musculoskeletal pain, neuropathic pain, neurocognitive difficulties, and sleep disturbances that can occur after an individual has recovered from a viral infection.
    Aims: This narrative review provides a summary of the sequelae of post-viral syndromes, viral agents that cause it, and the pathophysiology, treatment, and future considerations for research and targeted therapies.
    Methods: Medline, PubMed, and Embase databases were used to search for studies on viruses associated with post-viral syndrome.
    Conclusion: Much remains unknown regarding the pathophysiology of post-viral syndromes, and few studies have provided a comprehensive summary of the condition, agents that cause it, and successful treatment modalities. With the COVID-19 pandemic continuing to affect millions of people worldwide, the need for an understanding of the etiology of post-viral illness and how to help individuals cope with the sequalae is paramount.
    Language English
    Publishing date 2024-01-09
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2474-0527
    ISSN (online) 2474-0527
    DOI 10.1080/24740527.2023.2272999
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Important considerations with respect to reducing the transition from acute to persistent postoperative pain.

    Kojic, Katarina / Clarke, Hance

    Expert opinion on pharmacotherapy

    2021  Volume 22, Issue 7, Page(s) 779–782

    MeSH term(s) Acute Pain/drug therapy ; Chronic Pain/drug therapy ; Humans ; Pain, Postoperative/drug therapy
    Language English
    Publishing date 2021-02-26
    Publishing country England
    Document type Editorial
    ZDB-ID 2001535-5
    ISSN 1744-7666 ; 1465-6566
    ISSN (online) 1744-7666
    ISSN 1465-6566
    DOI 10.1080/14656566.2021.1892073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 5130: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Transitional Pain Medicine: novel pharmacological treatments for the management of moderate to severe postsurgical pain.

    Clarke, Hance

    Expert review of clinical pharmacology

    2016  Volume 9, Issue 3, Page(s) 345–349

    MeSH term(s) Acute Pain/drug therapy ; Acute Pain/etiology ; Analgesics/pharmacology ; Drug Design ; Humans ; Pain, Postoperative/drug therapy ; Severity of Illness Index
    Chemical Substances Analgesics
    Language English
    Publishing date 2016
    Publishing country England
    Document type Editorial ; Research Support, Non-U.S. Gov't
    ISSN 1751-2441
    ISSN (online) 1751-2441
    DOI 10.1586/17512433.2016.1129896
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The Future Is Bright: Highlighting Trainee Contributions to the Canadian Journal of Pain.

    Clarke, Hance / Bueno, Mariana / Harding, Erika / Trang, Tuan / McDougall, Jason J

    Canadian journal of pain = Revue canadienne de la douleur

    2024  Volume 7, Issue 2, Page(s) 2287032

    Language English
    Publishing date 2024-01-17
    Publishing country United States
    Document type Editorial
    ISSN 2474-0527
    ISSN (online) 2474-0527
    DOI 10.1080/24740527.2023.2287032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Automated, Vision-Based Goniometry and Range of Motion Calculation in Individuals With Suspected Ehlers-Danlos Syndromes/Generalized Hypermobility Spectrum Disorders: A Comparison of Pose-Estimation Libraries to Goniometric Measurements.

    Sabo, Andrea / Mittal, Nimish / Deshpande, Amol / Clarke, Hance / Taati, Babak

    IEEE journal of translational engineering in health and medicine

    2023  Volume 12, Page(s) 140–150

    Abstract: Generalized joint hypermobility (GJH) often leads clinicians to suspect a diagnosis of Ehlers Danlos Syndrome (EDS), but it can be difficult to objectively assess. Video-based goniometry has been proposed to objectively estimate joint range of motion in ... ...

    Abstract Generalized joint hypermobility (GJH) often leads clinicians to suspect a diagnosis of Ehlers Danlos Syndrome (EDS), but it can be difficult to objectively assess. Video-based goniometry has been proposed to objectively estimate joint range of motion in hyperextended joints. As part of an exam of joint hypermobility at a specialized EDS clinic, a mobile phone was used to record short videos of 97 adults (89 female, 35.0 ± 9.9 years old) undergoing assessment of the elbows, knees, shoulders, ankles, and fifth fingers. Five body keypoint pose-estimation libraries (AlphaPose, Detectron, MediaPipe-Body, MoveNet - Thunder, OpenPose) and two hand keypoint pose-estimation libraries (AlphaPose, MediaPipe-Hands) were used to geometrically calculate the maximum angle of hyperextension or hyperflexion of each joint. A custom domain-specific model with a MobileNet-v2 backbone finetuned on data collected as part of this study was also evaluated for the fifth finger movement. Spearman's correlation was used to analyze the angles calculated from the tracked joint positions, the angles calculated from manually annotated keypoints, and the angles measured using a goniometer. Moderate correlations between the angles estimated using pose-tracked keypoints and the goniometer measurements were identified for the elbow (rho =.722; Detectron), knee (rho =.608; MoveNet - Thunder), shoulder (rho =.632; MoveNet - Thunder), and fifth finger (rho =.786; custom model) movements. The angles estimated from keypoints predicted by open-source libraries at the ankles were not significantly correlated with the goniometer measurements. Manually annotated angles at the elbows, knees, shoulders, and fifth fingers were moderately to strongly correlated to goniometer measurements but were weakly correlated for the ankles. There was not one pose-estimation library which performed best across all joints, so the library of choice must be selected separately for each joint of interest. This work evaluates several pose-estimation models as part of a vision-based system for estimating joint angles in individuals with suspected joint hypermobility. Future applications of the proposed system could facilitate objective assessment and screening of individuals referred to specialized EDS clinics.
    MeSH term(s) Adult ; Humans ; Female ; Joint Instability/diagnosis ; Range of Motion, Articular ; Knee Joint ; Elbow Joint ; Ehlers-Danlos Syndrome/diagnosis
    Language English
    Publishing date 2023-11-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2696555-0
    ISSN 2168-2372 ; 2168-2372
    ISSN (online) 2168-2372
    ISSN 2168-2372
    DOI 10.1109/JTEHM.2023.3327691
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Feasibility of video-based joint hypermobility assessment in individuals with suspected Ehlers-Danlos syndromes/generalised hypermobility spectrum disorders: a single-site observational study protocol.

    Mittal, Nimish / Sabo, Andrea / Deshpande, Amol / Clarke, Hance / Taati, Babak

    BMJ open

    2022  Volume 12, Issue 12, Page(s) e068098

    Abstract: Introduction: Ehlers-Danlos syndromes (EDS)/generalised hypermobility spectrum disorders (G-HSD) affect the connective tissue of the body and present with a heterogeneous set of symptoms that pose a challenge for diagnosis. One of the main diagnostic ... ...

    Abstract Introduction: Ehlers-Danlos syndromes (EDS)/generalised hypermobility spectrum disorders (G-HSD) affect the connective tissue of the body and present with a heterogeneous set of symptoms that pose a challenge for diagnosis. One of the main diagnostic criteria of EDS/G-HSD is generalised joint hypermobility, which is currently assessed by clinicians during a physical exam. However, the practice for measuring joint hypermobility is inconsistent between clinicians, leading to high inter-rater variability. Often patients are misdiagnosed with EDS/G-HSD based on an incorrect hypermobility assessment, leading to increased referral rates and resource utilisation at specialised EDS clinics that results in unnecessary emotional distress for patients. An objective, validated and scalable method for assessing hypermobility might mitigate these issues and result in improved EDS/G-HSD patient care.
    Methods and analysis: This study will examine the use of videos obtained using a smartphone camera to assess the range of motion (ROM) and hypermobility of the joints assessed in Beighton score and more (spine, shoulders, elbows, knees, ankles, thumbs and fifth fingers) in individuals with suspected EDS/G-HSD. Short videos of participants will be captured as they undergo a formal assessment of joint hypermobility at the GoodHope EDS Clinic at Toronto General Hospital. Clinicians will measure the ROM at each joint using a clinical-grade goniometer to establish ground truth measurements. Open-source human pose-estimation libraries will be used to extract the locations of key joints from the videos. Deterministic and machine learning systems will be developed and evaluated for estimating the ROM at each joint. Results will be analysed separately for each joint and human pose-estimation library.
    Ethics and dissemination: This study was approved by the Research Ethics Board of the University Health Network in Toronto on 26 April 2022. Participants will provide written informed consent. Findings from this study will be published in peer-reviewed journals and presented at conferences.
    Trial registration number: NCT05366114.
    Language English
    Publishing date 2022-12-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2022-068098
    Database MEDical Literature Analysis and Retrieval System OnLINE

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