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  1. Article ; Online: How Refined Surgical Technical Solutions Can Make Bentall Operation a Low-Risk Procedure

    Giovanni Ruvolo / Claudia Altieri / Carlo Bassano / Dario Buioni / Paolo Nardi / Calogera Pisano

    Journal of Clinical Medicine, Vol 12, Iss 23, p

    20-Year Personal Experience at the “Root” of the Aortic Diseases—It Is Time to Change Surgical Guidelines

    2023  Volume 7330

    Abstract: 1) Objective: Twenty years’ experience of Bentall–De Bono operations by one surgeon. (2) Methods: From January 2003 to September 2023, four-hundred-and-two patients aged 65.9 ± 15 years underwent a Bentall operation. The EuroScore-2 was 5.0% ± 3.8%. ... ...

    Abstract (1) Objective: Twenty years’ experience of Bentall–De Bono operations by one surgeon. (2) Methods: From January 2003 to September 2023, four-hundred-and-two patients aged 65.9 ± 15 years underwent a Bentall operation. The EuroScore-2 was 5.0% ± 3.8%. Associated procedures were performed on 113 patients (28.1%). Results: Operative mortality was 1.2% ( n = 5), in particular 0.69% ( n = 2/289) for isolated Bentall operation, 2.65% ( n = 3/113) for combined procedures ( p < 0.05). Postoperative acute heart failure occurred in 38 patients (9.45%). Preoperative pulmonary hypertension (44 ± 14 vs. 33 ± 7 mmHg), cardiopulmonary bypass time (169 ± 61 min. vs. 124 ± 42 min.) and aortic cross-clamp time (133 ± 45 min. vs. 107 ± 34 min.) have been recognized as independent predictors of mortality and cardiac complications ( p < 0.05). Conclusions: In our experience, the Bentall operation was associated with low operative mortality and low rate of complications. For this reason, in agreement with the patients, we have modified surgical indication for ascending aortic aneurysms and now we think that it is time to change surgical guidelines.
    Keywords ascending aorta aneurysm ; Bentall–De Bono operation ; button technique ; surgical guidelines ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2023-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: A rare localization of papillary fibroelastoma

    Daniele Trombetti / Paolo Nardi / Laura Asta / Calogera Pisano / Claudia Altieri / Giovanni Ruvolo

    Polish Journal of Thoracic and Cardiovascular Surgery, Vol 19, Iss 2, Pp 103-

    2022  Volume 104

    Keywords Surgery ; RD1-811 ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2022-06-01T00:00:00Z
    Publisher Termedia Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Cardiac angiosarcoma

    Daniele Trombetti / Calogera Pisano / Maria Ferrante / Laura Asta / Claudia Altieri / Paolo Nardi / Dario Buioni / Giovanni Ruvolo

    Polish Journal of Thoracic and Cardiovascular Surgery, Vol 20, Iss 1, Pp 53-

    a formidable challenge

    2023  Volume 56

    Keywords Surgery ; RD1-811 ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher Termedia Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  4. Article ; Online: Treating Mitroflow dysfunction by means of an open valve-in-valve Perceval implantation

    Daniele Trombetti / Calogera Pisano / Claudia Altieri / Paolo Nardi / Sabrina Maria Ferrante / Laura Asta / Dario Buioni / Giovanni Ruvolo

    Polish Journal of Thoracic and Cardiovascular Surgery, Vol 20, Iss 1, Pp 65-

    2023  Volume 66

    Keywords Surgery ; RD1-811 ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2023-04-01T00:00:00Z
    Publisher Termedia Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Long-Term Follow-Up of Device-Assisted Clampless Off-Pump Coronary Artery Bypass Grafting Compared with Conventional On-Pump Technique

    Carlo Bassano / Paolo Nardi / Dario Buioni / Laura Asta / Calogera Pisano / Fabio Bertoldo / Claudia Altieri / Giovanni Ruvolo

    International Journal of Environmental Research and Public Health, Vol 19, Iss 275, p

    2022  Volume 275

    Abstract: Study objective: To evaluate the long-term outcomes of clampless off-pump coronary artery bypass grafting (C-OPCAB) compared with conventional on-pump double clamping coronary artery bypass grafting (C-CABG). Methods: From October 2006 to December 2011, ... ...

    Abstract Study objective: To evaluate the long-term outcomes of clampless off-pump coronary artery bypass grafting (C-OPCAB) compared with conventional on-pump double clamping coronary artery bypass grafting (C-CABG). Methods: From October 2006 to December 2011, 366 patients underwent isolated coronary artery bypass grafting. After propensity score matching of preoperative variables, 143 pairs were selected who received C-OPCAB with the use of device-assisted PAS-Port proximal venous graft anastomoses or C-CABG, performed by the same surgeon experienced in both techniques. Data of the two groups of patients were retrospectively analyzed up to 14 years of follow-up. Results: As compared with C-OPCAB, in the C-CABG patients, the performed number of grafts per patient was higher (2.9 ± 0.5 vs. 2.6 ± 0.6, p -value 0.0001). At 14 years, overall survival, including in-hospital death, was 64 ± 4.7% for the C-OPCAB vs. 55 ± 5.5% for the C-CABG, freedom from overall MACCEs 51 ± 6.2% vs. 41 ± 7.7%, and from late cardiac death 94 ± 2.4% vs. 96 ± 2.2% ( p -value not significant, for all comparisons). No significant statistical differences were observed in the actual rates of adverse events during follow-up. Independent predictors of survival were advanced age at operation ( p -value 0.001) and a lower mean value of preoperative left ventricular ejection fraction ( p -value 0.015). Conclusions: Our single-center study analysis suggests that clampless OPCAB using device-assisted proximal anastomoses proved to be not inferior to double-clamping CABG in the long-term follow-up, provided that involved surgeons are familiar with both techniques. These conclusions are supported by a large and long-term follow-up period, eliminating potential bias, i.e., by means of the propensity score matching and analyzing single-surgeon experience.
    Keywords coronary artery bypass grafting ; off-pump CABG ; device-assisted proximal venous graft anastomoses ; Medicine ; R
    Subject code 610
    Language English
    Publishing date 2022-12-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article ; Online: Stem cells and new intervention measures as emerging therapy in cardiac surgery

    Calogera Pisano / Paolo Nardi / Carmela Balistreri / Claudia Altieri / Fabio Bertoldo / Giovanni Ruvolo

    Polish Journal of Thoracic and Cardiovascular Surgery, Vol 17, Iss 1, Pp 1-

    2020  Volume 7

    Abstract: Cardiovascular disease (CVD) presents a great burden for elderly patients, their caregivers, and health systems. Structural and functional alterations of vessels accumulate throughout life, culminating in increased risk of developing CVD. Several ... ...

    Abstract Cardiovascular disease (CVD) presents a great burden for elderly patients, their caregivers, and health systems. Structural and functional alterations of vessels accumulate throughout life, culminating in increased risk of developing CVD. Several inflammatory pathway are involved in vascular ageing. The growing elderly population worldwide highlights the need to understand how aging promotes CVD in order to develop new strategies to confront this challenge. In this review we analyzed the role of stem cells and new intervention measures as emerging drugs for vascular aging.
    Keywords stem cell ; inflammation ; aging ; cardiovascular diseases ; Surgery ; RD1-811 ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2020-04-01T00:00:00Z
    Publisher Termedia Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: The effects of DeBakey type acute aortic dissection and preoperative peripheral and cardiac malperfusion on the outcomes after surgical repair

    Paolo Nardi / Carlo Bassano / Calogera Pisano / Claudia Altieri / Maria Ferrante / Monica Greci / Dario Buioni / Fabio Bertoldo / Andrea Farinaccio / Giovanni Ruvolo

    Polish Journal of Thoracic and Cardiovascular Surgery, Vol 18, Iss 1, Pp 1-

    2021  Volume 7

    Keywords type i ; ii aortic dissection ; malperfusion ; Surgery ; RD1-811 ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2021-05-01T00:00:00Z
    Publisher Termedia Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Circulating Levels of Ferritin, RDW, PTLs as Predictive Biomarkers of Postoperative Atrial Fibrillation Risk after Cardiac Surgery in Extracorporeal Circulation

    Claudia Altieri / Calogera Pisano / Labriola Vincenzo / Maria Sabrina Ferrante / Valentina Pellerito / Paolo Nardi / Carlo Bassano / Dario Buioni / Ernesto Greco / Giovanni Ruvolo / Carmela Rita Balistreri

    International Journal of Molecular Sciences, Vol 23, Iss 14800, p

    2022  Volume 14800

    Abstract: Postoperative atrial fibrillation (POAF) is the most common arrhythmia after cardiac surgery in conventional extracorporeal circulation (CECC), with an incidence of 15–50%. The POAF pathophysiology is not known, and no blood biomarkers exist. However, an ...

    Abstract Postoperative atrial fibrillation (POAF) is the most common arrhythmia after cardiac surgery in conventional extracorporeal circulation (CECC), with an incidence of 15–50%. The POAF pathophysiology is not known, and no blood biomarkers exist. However, an association between increased ferritin levels and increased AF risk, has been demonstrated. Based on such evidence, here, we evaluated the effectiveness of ferritin and other haematological parameters as POAF risk biomarkers in patients subjected to cardiac surgery. We enrolled 105 patients (mean age = 70.1 ± 7.1 years; 70 men and 35 females) with diverse heart pathologies and who were subjected to cardiothoracic surgery. Their blood samples were collected and used to determine hematological parameters. Electrocardiographic and echocardiographic parameters were also evaluated. The data obtained demonstrated significantly higher levels of serum ferritin, red cell distribution width (RDW), and platelets (PLTs) in POAF patients. However, the serum ferritin resulted to be the independent factor associated with the onset POAF risk. Thus, we detected the ferritin cut-off value, which, when ≥148.5 ng/mL, identifies the subjects at the highest POAF risk, and with abnormal ECG atrial parameters, such as PW indices, and altered structural heart disease variables. Serum ferritin, RDW, and PTLs represent predictive biomarkers of POAF after cardiothoracic surgery in CECC; particularly, serum ferritin combined with anormal PW indices and structural heart disease variables can represent an optimal tool for predicting not only POAF, but also the eventual stroke onset.
    Keywords postoperative atrial fibrillation ; cardiothoracic surgery ; conventional extracorporeal circulation ; serum ferritin levels ; PW indices ; POAF onset biomarkers ; Biology (General) ; QH301-705.5 ; Chemistry ; QD1-999
    Subject code 610
    Language English
    Publishing date 2022-11-01T00:00:00Z
    Publisher MDPI AG
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article ; Online: The impact of dual antiplatelet therapy administration on the risk of bleeding complications during coronary artery bypass surgery

    Paolo Nardi / Calogera Pisano / Maria Turturici / Fabio Bertoldo / Vito Renato Maggio / Carlo Bassano / Dario Buioni / Antonio Scafuri / Claudia Altieri / Giovanni Ruvolo

    Polish Journal of Thoracic and Cardiovascular Surgery, Vol 18, Iss 3, Pp 145-

    2021  Volume 151

    Keywords dual antiplatelet therapy ; coronary artery bypass grafting ; p2y12 inhibitors ; Surgery ; RD1-811 ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2021-10-01T00:00:00Z
    Publisher Termedia Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  10. Article ; Online: The benefit of a preoperative respiratory protocol and musculoskeletal exercise in patients undergoing cardiac surgery

    Paolo Nardi / Calogera Pisano / Claudia Altieri / Dario Buioni / Carlo Pedicelli / Silvia Saulle / Romana Dandi / Alessia Romano / Annamaria Servadio / Alessandra Gianlorenzi / Katia Emili / Giovanni Ruvolo

    Polish Journal of Thoracic and Cardiovascular Surgery, Vol 17, Iss 2, Pp 94-

    2020  Volume 100

    Keywords respiratory protocol ; cardiac surgery ; musculoskeletal exercise ; Surgery ; RD1-811 ; Internal medicine ; RC31-1245
    Language English
    Publishing date 2020-07-01T00:00:00Z
    Publisher Termedia Publishing House
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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