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  1. Book: Interventional cardiology

    Cleman, Michael W.

    (Cardiology clinics ; 6,3)

    1988  

    Author's details Michael W. Cleman ..., guest ed
    Series title Cardiology clinics ; 6,3
    Collection
    Keywords Cardiovascular Diseases / therapy ; Angioplasty, Balloon ; Catheterization ; Heart-Assist Devices
    Size VI S., S. 321 - 463 : zahlr. Ill., graph. Darst.
    Publisher Saunders
    Publishing place Philadelphia u.a.
    Publishing country United States
    Document type Book
    HBZ-ID HT003279681
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: SGLT-2i and Cardiovascular Prognosis.

    Siasos, Gerasimos / Stampouloglou, Panagiota K / Bletsa, Evanthia / Paschou, Stavroula A / Oikonomou, Evangelos / Giannopoulos, Georgios / Deftereos, Spyridon / Cleman, Michael W / Tousoulis, Dimitrios

    Current pharmaceutical design

    2020  Volume 26, Issue 32, Page(s) 3905–3907

    MeSH term(s) Cardiovascular Diseases/drug therapy ; Diabetes Mellitus, Type 2 ; Humans ; Hypoglycemic Agents ; Prognosis ; Sodium-Glucose Transporter 2 Inhibitors
    Chemical Substances Hypoglycemic Agents ; Sodium-Glucose Transporter 2 Inhibitors
    Language English
    Publishing date 2020-09-30
    Publishing country United Arab Emirates
    Document type Journal Article
    ZDB-ID 1304236-1
    ISSN 1873-4286 ; 1381-6128
    ISSN (online) 1873-4286
    ISSN 1381-6128
    DOI 10.2174/138161282632200811172751
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Antioxidant treatment in peripheral artery disease: the rationale is there, but what about clinical results?

    Giannopoulos, Georgios / Angelidis, Christos / Vogiatzi, Georgia / Cleman, Michael W / Deftereos, Spyridon

    Current opinion in pharmacology

    2018  Volume 39, Page(s) 53–59

    Abstract: Peripheral arterial disease is a major cause of morbidity and disability and has been consistently associated with an adverse overall prognosis. Oxidative stress has been linked to vascular disease, with several suggested pathogenetic mechanisms, leading ...

    Abstract Peripheral arterial disease is a major cause of morbidity and disability and has been consistently associated with an adverse overall prognosis. Oxidative stress has been linked to vascular disease, with several suggested pathogenetic mechanisms, leading to various insults of the arterial wall and, ultimately, to atherothrombotic disease. Considering that the pathophysiological background is quite compelling, attenuation of oxidative processes by means of various substances with antioxidant properties has been conceived as a promising therapeutic target. However, clinical results have been mostly disappointing and 'antioxidant' therapies are still far from being integrated into treatment algorithms for vascular disease.
    MeSH term(s) Antioxidants/therapeutic use ; Humans ; Oxidative Stress ; Peripheral Arterial Disease/drug therapy
    Chemical Substances Antioxidants
    Language English
    Publishing date 2018-02-24
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2037057-X
    ISSN 1471-4973 ; 1471-4892
    ISSN (online) 1471-4973
    ISSN 1471-4892
    DOI 10.1016/j.coph.2018.01.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Inflammation fueling atrial fibrillation substrate: seeking ways to "cool" the heart.

    Giannopoulos, Georgios / Cleman, Michael W / Deftereos, Spyridon

    Medicinal chemistry (Shariqah (United Arab Emirates))

    2014  Volume 10, Issue 7, Page(s) 663–671

    Abstract: Atrial fibrillation (AF) is the most common chronic arrhythmia and a source of significant morbidity and mortality. Previous studies have identified numerous risk factors for the development of AF, including hypertension, diabetes mellitus and heart ... ...

    Abstract Atrial fibrillation (AF) is the most common chronic arrhythmia and a source of significant morbidity and mortality. Previous studies have identified numerous risk factors for the development of AF, including hypertension, diabetes mellitus and heart failure, which have known pathophysiologic links with inflammatory processes. The importance of inflammation in inducing and perpetuating AF has been highlighted not only by experimental, epidemiological and cohort observational studies, but also by clinical trials providing evidence that inflammatory pathways are involved in AF pathogenesis. Local and systemic measurements of biomarkers and inflammatory mediators, as well as atrial biopsy studies have also given insight as to the purported relationship between this arrhythmia and inflammation. However, the link between inflammation and AF is still poorly defined and several issues remain unresolved. The present review offers an overview of existing evidence supporting the "inflammatory" hypothesis for AF pathophysiology and potential therapeutic means for counteracting this "foul interplay" between arrhythmia and inflammation.
    MeSH term(s) Atrial Fibrillation/complications ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/metabolism ; Atrial Fibrillation/physiopathology ; Humans ; Inflammation/complications ; Inflammation/drug therapy ; Inflammation/metabolism ; Inflammation/physiopathology
    Language English
    Publishing date 2014-03-01
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 1875-6638
    ISSN (online) 1875-6638
    DOI 10.2174/1573406410666140318110100
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A balloon-expandable sheath facilitates transfemoral TAVR in patients with peripheral vascular disease and tortuosity.

    Goldsweig, Andrew M / Faheem, Osman / Cleman, Michael W / Forrest, John K

    Therapeutic advances in cardiovascular disease

    2015  Volume 9, Issue 3, Page(s) 95–102

    Abstract: Objectives: We sought to perform transcatheter aortic valve replacement (TAVR) via the transfemoral approach in patients with peripheral arterial disease (PAD), small caliber ileofemoral vessels and vascular tortuosity.: Background: For patients with ...

    Abstract Objectives: We sought to perform transcatheter aortic valve replacement (TAVR) via the transfemoral approach in patients with peripheral arterial disease (PAD), small caliber ileofemoral vessels and vascular tortuosity.
    Background: For patients with increased surgical risk, TAVR is associated with a higher 1-year survival rate than surgical aortic valve replacement (SAVR). Transfemoral vascular access for TAVR results in superior outcomes versus procedures performed via other routes in terms of mortality, morbidity and healthcare economics. In many patients, the ability to safely perform the procedure via the transfemoral approach is limited by narrow, diseased and tortuous ileofemoral vasculature.
    Methods: We employed the SoloPath Balloon Expandable TransFemoral Access System (Terumo Med. Corp., Tokyo, Japan) to perform transfemoral TAVR in five patients with PAD, small caliber ileofemoral vessels and vascular tortuosity.
    Results: We report our experience using this balloon-expandable sheath during 5 cases of transfemoral TAVR in patients with inhospitable ileofemoral vasculature of mean diameter ⩽ 5.8 mm. The unexpanded sheath's malleable structure and hydrophilic coating permitted deployment despite severe stenoses and tortuosity. Subsequent inflation to 18 Fr facilitated successful TAVR. Postprocedural angiography demonstrated no significant vascular access complications. In one case, the entire procedure was performed percutaneously, without common femoral artery surgical cutdown.
    Conclusions: The SoloPath sheath system permits transfemoral TAVR in patients with PAD small caliber ileofemoral vessels and vascular tortuosity. The transfemoral balloon-expandable sheath allowed these patients to avoid the increased morbidity and mortality risks associated with direct aortic or transapical access.
    MeSH term(s) Aortic Valve/physiopathology ; Aortic Valve/transplantation ; Arteries/abnormalities ; Arteries/surgery ; Heart Valve Prosthesis ; Heart Valve Prosthesis Implantation/methods ; Humans ; Joint Instability/surgery ; Peripheral Arterial Disease/surgery ; Skin Diseases, Genetic/surgery ; Survival Rate ; Treatment Outcome ; Vascular Malformations/surgery
    Language English
    Publishing date 2015-06
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2485062-7
    ISSN 1753-9455 ; 1753-9447
    ISSN (online) 1753-9455
    ISSN 1753-9447
    DOI 10.1177/1753944715575970
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Remote Ischemic Conditioning and Renal Protection.

    Giannopoulos, Georgios / Vrachatis, Dimitrios A / Panagopoulou, Vasiliki / Vavuranakis, Manolis / Cleman, Michael W / Deftereos, Spyridon

    Journal of cardiovascular pharmacology and therapeutics

    2017  Volume 22, Issue 4, Page(s) 321–329

    Abstract: Over the course of the last 2 decades, the concept of remote ischemic conditioning (RIC) has attracted considerable research interest, because RIC, in most of its embodiments offers an inexpensive way of protecting tissues against ischemic damage ... ...

    Abstract Over the course of the last 2 decades, the concept of remote ischemic conditioning (RIC) has attracted considerable research interest, because RIC, in most of its embodiments offers an inexpensive way of protecting tissues against ischemic damage inflicted by a number of medical conditions or procedures. Acute kidney injury (AKI) is a common side effect in the context of various medical procedures, and RIC has been suggested as a means of reducing its incidence. Outcomes regarding kidney function have been reported in numerous studies that evaluated the effects of RIC in a variety of settings (eg, cardiac surgery, interventions requiring intravenous administration of contrast media). Although several individual studies have implied a beneficial effect of RIC in preserving kidney function, 3 recently published randomized controlled trials evaluating more than 1000 patients each (Effect of Remote Ischemic Preconditioning in the Cardiac Surgery, Remote Ischaemic Preconditioning for Heart Surgery, and ERICCA) were negative. However, AKI or any other index of renal function was not a stand-alone primary end point in any of these trials. On the other hand, a range of meta-analyses (each including thousands of participants) have reported mixed results, with the most recent among them showing benefit from RIC, pinpointing at the same time a number of shortcomings in published studies, adversely affecting the quality of available data. The present review provides a critical appraisal of the current state of this field of research. It is the opinion of the authors of this review that there is a clear need for a common clinical trial framework for ischemic conditioning studies. If the current babel of definitions, procedures, outcomes, and goals persists, it is most likely that soon ischemic conditioning will be "yesterday's news" with no definitive conclusions having been reached in terms of its real clinical utility.
    Language English
    Publishing date 2017-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1329372-2
    ISSN 1940-4034 ; 1074-2484
    ISSN (online) 1940-4034
    ISSN 1074-2484
    DOI 10.1177/1074248417702480
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Trends in volume and risk profiles of patients undergoing isolated surgical and transcatheter aortic valve replacement.

    Mori, Makoto / Bin Mahmood, Syed Usman / Geirsson, Arnar / Yun, James J / Cleman, Michael W / Forrest, John K / Mangi, Abeel A

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2018  Volume 93, Issue 6, Page(s) E337–E342

    Abstract: Background: Recent reports describe increases in the case volume of surgical aortic valve replacement (SAVR) after centers establish a transcatheter aortic valve replacement (TAVR) program. We investigate contemporary temporal trends in SAVR and TAVR ... ...

    Abstract Background: Recent reports describe increases in the case volume of surgical aortic valve replacement (SAVR) after centers establish a transcatheter aortic valve replacement (TAVR) program. We investigate contemporary temporal trends in SAVR and TAVR case volumes and risk profiles at a high volume academic medical center.
    Methods: We conducted a retrospective, descriptive evaluation of consecutive patients who underwent TAVR (n = 538) or SAVR (n = 657) in 2011-2016. The STS predicted risk of mortality (PROM) for isolated SAVR was used to calculate PROM for both SAVR and TAVR patients. Patients were stratified based on STS PROM as follows: low risk (<4%), intermediate risk (4-8%), and high risk (≥8%). Temporal changes in patient risk-profile were characterized descriptively.
    Results: Median STS PROM for the study period was 6.3% and 2.0% for TAVR and SAVR cohorts, respectively (P < 0.001). Since 2011, TAVR volume consistently increased, while SAVR volume increased initially, peaking in 2013 and steadily declined. The STS PROM for SAVR remained stable during the entire study period, while that for TAVR showed a steady decline. The proportions of intermediate and low STS PROM patients undergoing TAVR increased. Proportions of each risk category in SAVR cohort remained stable over time.
    Conclusions: SAVR volume increased initially but declined eventually following the implementation of TAVR program. The distribution of the STS PROM in TAVR cohort changed dramatically with increasing proportion of patients in lower risk categories. These findings suggest the converging patient populations in TAVR and SAVR, which may be associated with the decline in the overall SAVR volume.
    MeSH term(s) Academic Medical Centers/trends ; Aged ; Aged, 80 and over ; Aortic Valve/surgery ; Female ; Heart Valve Prosthesis Implantation/adverse effects ; Heart Valve Prosthesis Implantation/mortality ; Heart Valve Prosthesis Implantation/trends ; Hospitals, High-Volume/trends ; Humans ; Male ; Patient Reported Outcome Measures ; Practice Patterns, Physicians'/trends ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Time Factors ; Transcatheter Aortic Valve Replacement/adverse effects ; Transcatheter Aortic Valve Replacement/mortality ; Transcatheter Aortic Valve Replacement/trends ; Treatment Outcome
    Language English
    Publishing date 2018-09-30
    Publishing country United States
    Document type Comparative Study ; Journal Article ; Observational Study
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.27855
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Percutaneous right ventricular support during catheter ablation of intra-atrial reentrant tachycardia in an adult with a mustard baffle--a novel use of the Impella device.

    Fishberger, Steven B / Asnes, Jeremy D / Rollinson, Nancy L / Cleman, Michael W

    Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing

    2010  Volume 29, Issue 1, Page(s) 69–72

    Abstract: Late sequelea following a Mustard operation for transposition of the great arteries (TGA) include atrial arrhythmias and dysfunction of the systemic right ventricle. Catheter mapping and ablation of atrial tachycardia in the setting of significant right ... ...

    Abstract Late sequelea following a Mustard operation for transposition of the great arteries (TGA) include atrial arrhythmias and dysfunction of the systemic right ventricle. Catheter mapping and ablation of atrial tachycardia in the setting of significant right ventricular dysfunction may result in hemodynamic compromise. We report the novel use of the Impella percutaneous microaxial flow pump to support cardiac output in an adult patient with a Mustard operation for TGA who experienced a cardiac arrest during a prior ablation attempt. The Impella device was placed via a retrograde approach across the aortic valve into the right ventricle providing hemodynamic stability for successful mapping and ablation of intra-atrial reentrant tachycardia.
    MeSH term(s) Adult ; Body Surface Potential Mapping ; Cardiac Output/physiology ; Cardiac Pacing, Artificial/methods ; Cardiac Surgical Procedures/methods ; Catheter Ablation/methods ; Combined Modality Therapy ; Electrocardiography ; Follow-Up Studies ; Heart-Assist Devices ; Hemodynamics/physiology ; Humans ; Male ; Severity of Illness Index ; Tachycardia, Ectopic Atrial/diagnosis ; Tachycardia, Ectopic Atrial/surgery ; Tachycardia, Ectopic Atrial/therapy ; Transposition of Great Vessels/complications ; Transposition of Great Vessels/diagnosis ; Transposition of Great Vessels/surgery ; Treatment Outcome
    Language English
    Publishing date 2010-04-13
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 1329179-8
    ISSN 1572-8595 ; 1383-875X
    ISSN (online) 1572-8595
    ISSN 1383-875X
    DOI 10.1007/s10840-010-9478-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Ventricular septal rupture complicating acute myocardial infarction: Incidence, treatment, and outcomes among medicare beneficiaries 1999-2014.

    Goldsweig, Andrew M / Wang, Yun / Forrest, John K / Cleman, Michael W / Minges, Karl E / Mangi, Abeel A / Aronow, Herbert D / Krumholz, Harlan M / Curtis, Jeptha P

    Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions

    2018  Volume 92, Issue 6, Page(s) 1104–1115

    Abstract: Objectives: The present study was designed to assess whether the incidence and outcomes of VSR-AMI have changed in the era of timely primary PCI.: Background: Ventricular septal rupture (VSR) is a rare but frequently fatal complication of acute ... ...

    Abstract Objectives: The present study was designed to assess whether the incidence and outcomes of VSR-AMI have changed in the era of timely primary PCI.
    Background: Ventricular septal rupture (VSR) is a rare but frequently fatal complication of acute myocardial infarction (AMI).
    Methods: We conducted a retrospective cohort study of all Medicare fee-for-service beneficiaries from 1999 to 2014 to examine trends in the incidence, surgical and percutaneous repair, and 30-day and 1-year mortality of VSR-AMI.
    Results: The annual incidence of VSR-AMI hospitalization declined by 41.6% from 197 patients per 100,000 AMIs in 1999 to 115 patients per 100,000 AMIs in 2014 (P < 0.001). The 30-day VSR-AMI repair rate decreased from 49.9% in 1999 to 33.3% in 2014 (P < 0.001). In 2014, 82.9% of repairs were performed surgically and 17.1% percutaneously. VSR-AMI mortality rates were high (60.2% at 30 days; 68.5% at 1 year) and changed minimally over the study period with adjusted 30-day mortality per year Odds Ratio (OR) 0.99 (95% confidence interval [CI] 0.98-1.01) and adjusted 1-year mortality per year OR 0.98 (95% CI 0.97-1.00). Across the 16 years of data, unadjusted mortality rates were lower in patients undergoing repair than in unrepaired patients at 30 days (mean 51.7% and 65.7%, P ≤ 0.01) and 1 year (mean 62.0% and 72.8%, P < 0.01).
    Conclusions: In the era of increased timely primary PCI, the incidence of VSR-AMI hospitalization declined but its associated mortality rate remained high. Rates of VSR repair decreased from 1999 to 2014 despite increased use of percutaneous repair.
    MeSH term(s) Aged ; Cardiac Catheterization/adverse effects ; Cardiac Catheterization/mortality ; Cardiac Catheterization/trends ; Cardiac Surgical Procedures/adverse effects ; Cardiac Surgical Procedures/mortality ; Cardiac Surgical Procedures/trends ; Female ; Humans ; Incidence ; Male ; Medicare ; Myocardial Infarction/diagnostic imaging ; Myocardial Infarction/epidemiology ; Myocardial Infarction/mortality ; Myocardial Infarction/therapy ; Percutaneous Coronary Intervention/adverse effects ; Percutaneous Coronary Intervention/mortality ; Percutaneous Coronary Intervention/trends ; Prevalence ; Retrospective Studies ; Risk Assessment ; Risk Factors ; Time Factors ; Treatment Outcome ; United States/epidemiology ; Ventricular Septal Rupture/diagnostic imaging ; Ventricular Septal Rupture/epidemiology ; Ventricular Septal Rupture/mortality ; Ventricular Septal Rupture/therapy
    Language English
    Publishing date 2018-03-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1459995-8
    ISSN 1522-726X ; 1522-1946
    ISSN (online) 1522-726X
    ISSN 1522-1946
    DOI 10.1002/ccd.27576
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Intra--and Intercellular Calcium Handling in Pulmonary Arterial Hypertension.

    Mouratoglou, Sophia-Anastasia / Giannakoulas, George / Deftereos, Spyridon / Giannopoulos, Georgios / Angelidis, Christos / Cleman, Michael W / Vassilikos, Vassilios P

    Medicinal chemistry (Shariqah (United Arab Emirates))

    2015  Volume 12, Issue 2, Page(s) 162–169

    Abstract: Pulmonary arterial hypertension (PAH) is a serious life threatening disease that leads to right heart failure and death. Elevated pulmonary vascular resistance (PVR) is the main pathophysiological component that leads to elevated pulmonary arterial ... ...

    Abstract Pulmonary arterial hypertension (PAH) is a serious life threatening disease that leads to right heart failure and death. Elevated pulmonary vascular resistance (PVR) is the main pathophysiological component that leads to elevated pulmonary arterial pressures and increased right ventricular afterload. Increased PVR is related to different mechanisms that include vasoconstriction, proliferative and obstructive remodeling of the pulmonary vessel wall and in situ thrombosis. Numerous molecular, genetic and humoral abnormalities have been proposed to play an important role in pulmonary vasoconstriction and remodeling. Of those, calcium (Ca(+2)) is a well recognized parameter involved in the pathogenetic mechanisms of PAH, because of its twofold role in both vasoconstriction and pulmonary artery smooth muscle cell (PASMC) proliferation. The aim of this review is to focus on Ca(+2) handling and dysregulation in PASMC of PAH patients.
    MeSH term(s) Animals ; Calcium/metabolism ; Calcium Channels/physiology ; Cardiovascular Agents/pharmacology ; Cardiovascular Agents/therapeutic use ; Endoplasmic Reticulum/physiology ; Extracellular Space/metabolism ; Humans ; Hypertension, Pulmonary/drug therapy ; Hypertension, Pulmonary/metabolism ; Hypertension, Pulmonary/physiopathology ; Intracellular Space/metabolism ; Pulmonary Artery/physiopathology ; Sarcoplasmic Reticulum/physiology ; Vascular Remodeling/physiology ; Vasoconstriction/physiology
    Chemical Substances Calcium Channels ; Cardiovascular Agents ; Calcium (SY7Q814VUP)
    Language English
    Publishing date 2015-09-18
    Publishing country Netherlands
    Document type Journal Article ; Review
    ISSN 1875-6638
    ISSN (online) 1875-6638
    DOI 10.2174/157340641202160209095051
    Database MEDical Literature Analysis and Retrieval System OnLINE

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