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  1. Article ; Online: Clinical diagnosis in paediatric patients at urban primary health care facilities in southern Malawi

    Mtisunge Joshua Gondwe / Marc Y. R. Henrion / Thomasena O’Byrne / Clemens Masesa / Norman Lufesi / Queen Dube / Maureen D. Majamanda / Martha Makwero / David G. Lalloo / Nicola Desmond

    BMC Health Services Research, Vol 21, Iss 1, Pp 1-

    a longitudinal observational study

    2021  Volume 10

    Abstract: Abstract Background Despite health centres being the first point of contact of care, there are challenges faced in providing care to patients at this level. In Malawi, service provision barriers reported at this level included long waiting times, high ... ...

    Abstract Abstract Background Despite health centres being the first point of contact of care, there are challenges faced in providing care to patients at this level. In Malawi, service provision barriers reported at this level included long waiting times, high numbers of patients and erratic consultation systems which lead to mis-diagnosis and delayed referrals. Proper case management at this level of care is critical to prevent severe disease and deaths in children. We aimed to adopt Emergency, Triage, Assessment and Treatment algorithm (ETAT) to improve ability to identify severe illness in children at primary health centre (PHC) through comparison with secondary level diagnoses. Methods We implemented ETAT mobile Health (mHealth) at eight urban PHCs in Blantyre, Malawi between April 2017 and September 2018. Health workers and support staff were trained in mHealth ETAT. Stabilisation rooms were established and equipped with emergency equipment. All PHCs used an electronic tracking system to triage and track sick children on referral to secondary care, facilitated by a unique barcode. Support staff at PHC triaged sick children using ETAT Emergency (E), Priority (P) and Queue (Q) symptoms and clinician gave clinical diagnosis. The secondary level diagnosis was considered as a gold standard. We used statistical computing software R (v3.5.1) and used exact 95% binomial confidence intervals when estimating diagnosis agreement proportions. Results Eight-five percentage of all cases where assigned to E (9.0%) and P (75.5%) groups. Pneumonia was the most common PHC level diagnosis across all three triage groups (E, P, Q). The PHC level diagnosis of trauma was the most commonly confirmed diagnosis at secondary level facility (85.0%), while a PHC diagnosis of pneumonia was least likely to be confirmed at secondary level (39.6%). The secondary level diagnosis least likely to have been identified at PHC level was bronchiolitis 3 (5.2%). The majority of bronchiolitis cases (n = 50; (86.2%) were classified as pneumonia at the PHC ...
    Keywords ETAT ; Triage ; Primary health Centre ; Paediatrics ; Diagnosis ; Stabilisation ; Public aspects of medicine ; RA1-1270
    Subject code 360
    Language English
    Publishing date 2021-02-01T00:00:00Z
    Publisher BMC
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: Informing prevention of stillbirth and preterm birth in Malawi

    Rachael Wood / Jane E Norman / Hilary Pinnock / Harry Campbell / Rebecca M Reynolds / Beatrix von Wissmann / Elizabeth Wastnedge / Donald Waters / Luis A Gadama / Clemens Masesa / Elizabeth Chodzaza / Sarah Jane Stock / Enita Makwakwa / Catherine Bamuya / Esmie Banda / James Boardman / Effie Chipeta / Mia Crampin / Sarah Cunningham Burley /
    Jean Desire Kabamba / Elizabeth Grant / Caroline Hollins Martin / Aisha Holloway / Khondwhani Kawaza / Doris Kayambo / Corrine Love / Brian Magowan / Monica Malata / Martha Masamba / Fadhila Mazanderani / Gladys Membe- Gadama / Catherine Mkandawire / Patricia Munthali / Peter Mwaba / Shakira Namisengo / Everist Njelesani / Linda Nyondo-Mipando / Muriel Syacumpi / Frank Taulo / Alexandra Viner

    BMJ Open, Vol 10, Iss

    development of a minimum dataset for health facilities participating in the DIPLOMATIC collaboration

    2020  Volume 11

    Abstract: Objective The global research group, DIPLOMATIC (Using eviDence, Implementation science, and a clinical trial PLatform to Optimise MATernal and newborn health in low Income Countries), aims to reduce stillbirths and preterm births and optimise outcomes ... ...

    Abstract Objective The global research group, DIPLOMATIC (Using eviDence, Implementation science, and a clinical trial PLatform to Optimise MATernal and newborn health in low Income Countries), aims to reduce stillbirths and preterm births and optimise outcomes for babies born preterm. Minimum datasets for routine data collection in healthcare facilities participating in DIPLOMATIC (initially in Malawi) were designed to assist understanding of baseline maternal and neonatal care processes and outcomes, and facilitate evaluation of improvement interventions and pragmatic clinical trials.Design Published and grey literature was reviewed alongside extensive in-country consultation to define relevant clinical best practice guidance, and the existing local data and reporting infrastructure, to identify requirements for the minimum datasets. Data elements were subjected to iterative rounds of consultation with topic experts in Malawi and Scotland, the relevant Malawian professional bodies and the Ministry of Health in Malawi to ensure relevance, validity and feasibility.Setting Antenatal, maternity and specialist neonatal care in Malawi.Results The resulting three minimum datasets cover the maternal and neonatal healthcare journey for antenatal, maternity and specialist neonatal care, with provision for effective linkage of records for mother/baby pairs. They can facilitate consistent, precise recording of relevant outcomes (stillbirths, preterm births, neonatal deaths), risk factors and key care processes.Conclusions Poor quality routine data on care processes and outcomes constrain healthcare system improvement. The datasets developed for implementation in DIPLOMATIC partner facilities reflect, and hence support delivery of, internationally agreed best practice for maternal and newborn care in low-income settings. Informed by extensive consultation, they are designed to integrate with existing local data infrastructure and reporting as well as meeting research data needs. This work provides a transferable example of strengthening data infrastructure to underpin a learning healthcare system approach in low-income settings.DIPLOMATIC is funded by the UK National Institute for Health Research.
    Keywords Medicine ; R
    Subject code 360
    Language English
    Publishing date 2020-11-01T00:00:00Z
    Publisher BMJ Publishing Group
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Long-term biological and behavioural impact of an adolescent sexual health intervention in Tanzania

    Aoife M Doyle / David A Ross / Kaballa Maganja / Kathy Baisley / Clemens Masesa / Aura Andreasen / Mary L Plummer / Angela I N Obasi / Helen A Weiss / Saidi Kapiga / Deborah Watson-Jones / John Changalucha / Richard J Hayes / MEMA kwa Vijana Trial Study Group

    PLoS Medicine, Vol 7, Iss 6, p e

    follow-up survey of the community-based MEMA kwa Vijana Trial.

    2010  Volume 1000287

    Abstract: Background The ability of specific behaviour-change interventions to reduce HIV infection in young people remains questionable. Since January 1999, an adolescent sexual and reproductive health (SRH) intervention has been implemented in ten randomly ... ...

    Abstract Background The ability of specific behaviour-change interventions to reduce HIV infection in young people remains questionable. Since January 1999, an adolescent sexual and reproductive health (SRH) intervention has been implemented in ten randomly chosen intervention communities in rural Tanzania, within a community randomised trial (see below; NCT00248469). The intervention consisted of teacher-led, peer-assisted in-school education, youth-friendly health services, community activities, and youth condom promotion and distribution. Process evaluation in 1999-2002 showed high intervention quality and coverage. A 2001/2 intervention impact evaluation showed no impact on the primary outcomes of HIV seroincidence and herpes simplex virus type 2 (HSV-2) seroprevalence but found substantial improvements in SRH knowledge, reported attitudes, and some reported sexual behaviours. It was postulated that the impact on "upstream" knowledge, attitude, and reported behaviour outcomes seen at the 3-year follow-up would, in the longer term, lead to a reduction in HIV and HSV-2 infection rates and other biological outcomes. A further impact evaluation survey in 2007/8 ( approximately 9 years post-intervention) tested this hypothesis. Methods and findings This is a cross-sectional survey (June 2007 through July 2008) of 13,814 young people aged 15-30 y who had attended trial schools during the first phase of the MEMA kwa Vijana intervention trial (1999-2002). Prevalences of the primary outcomes HIV and HSV-2 were 1.8% and 25.9% in males and 4.0% and 41.4% in females, respectively. The intervention did not significantly reduce risk of HIV (males adjusted prevalence ratio [aPR] 0.91, 95%CI 0.50-1.65; females aPR 1.07, 95%CI 0.68-1.67) or HSV-2 (males aPR 0.94, 95%CI 0.77-1.15; females aPR 0.96, 95%CI 0.87-1.06). The intervention was associated with a reduction in the proportion of males reporting more than four sexual partners in their lifetime (aPR 0.87, 95%CI 0.78-0.97) and an increase in reported condom use at last sex with a ...
    Keywords Medicine ; R
    Subject code 360 ; 306
    Language English
    Publishing date 2010-06-01T00:00:00Z
    Publisher Public Library of Science (PLoS)
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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