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  1. Article ; Online: Long-term Airway Outcomes and Interventions in Children With Oesophageal Atresia With Tracheoesophageal Fistula: A 20-year Single Centre Observational Study.

    Davis, Sandra E / Davis, Carl / Patel, Neil / Kubba, Haytham / Clement, W Andrew

    Journal of pediatric surgery

    2024  

    Abstract: Background: Airway anomalies, symptoms and interventions are commonly reported in children with oesophageal atresia with tracheoesophageal fistula (OA/TOF). The purpose of this study was to assess the incidence of these airway pathologies and those ... ...

    Abstract Background: Airway anomalies, symptoms and interventions are commonly reported in children with oesophageal atresia with tracheoesophageal fistula (OA/TOF). The purpose of this study was to assess the incidence of these airway pathologies and those requiring interventions in the long-term.
    Methods: A retrospective case note review of all patients admitted to the Neonatal Unit at the Royal Hospital for Children, Glasgow between January 2000 and December 2015 diagnosed with OA/TOF. Included patients had a minimum of 5 years follow-up.
    Results: 121 patients were identified. 118 proceeded to OA/TOF repair. 115 patients had long-term follow-up data. Ninety-five (83%) children had one or more airway symptom recorded. Thirty-six (31%) neonates underwent airway endoscopy at the time of their initial OA/TOF repair. Forty-six (40%) children underwent airway endoscopy at a later date due to airway symptoms. Airway pathologies identified included airway malacia, thirty-two (28%), subglottic stenosis, eleven (10%), tracheal pouch, twenty-five (22%), laryngeal cleft, seven (6%) and recurrent fistula, five (4%). Airway interventions included endoscopic division of tracheal pouch, ten (9%), tracheostomy, seven (6%), aortopexy, six (5%), repair of recurrent fistula, five (4%), endoscopic repair of laryngeal cleft, three (3%) and four (3%) required open airway reconstruction for subglottic stenosis. One child (1%) remains tracheostomy dependent.
    Conclusions: Long-term airway pathologies are common in children with OA/TOF. Many of these are remediable with surgical intervention. Clinicians should be cognisant of this and refer to Airway Services appropriately.
    Language English
    Publishing date 2024-02-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80165-3
    ISSN 1531-5037 ; 0022-3468
    ISSN (online) 1531-5037
    ISSN 0022-3468
    DOI 10.1016/j.jpedsurg.2024.02.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Tracheostomy decannulation at the Royal Hospital for Sick Children in Glasgow: Predictors of success and failure.

    Beaton, Fiona / Baird, Tracy-Anne / Clement, W Andrew / Kubba, Haytham

    International journal of pediatric otorhinolaryngology

    2016  Volume 90, Page(s) 204–209

    Abstract: Background: Tracheostomy techniques, indications and care are extensively covered in the literature. However, little is written about the process of removing the tracheostomy tube. At the Royal Hospital for Sick Children in Glasgow we use a stepwise ... ...

    Abstract Background: Tracheostomy techniques, indications and care are extensively covered in the literature. However, little is written about the process of removing the tracheostomy tube. At the Royal Hospital for Sick Children in Glasgow we use a stepwise ward-based protocol for safe tracheostomy decannulation. Our aim therefore was to review all the paediatric tracheostomy decannulations that we attempted over the last 3 years to evaluate our protocol, to determine our success rate and to see whether any modifications to the protocol are required.
    Method: We reviewed all patients who had undergone ward decannulation between January 2012 and May 2015. We extracted data from clinical records including patient characteristics, indications for tracheostomy, timing of decannulation and success or failure of the process.
    Results: The 45 children in the study underwent 57 attempts at decannulation during the study period. 25 were male (56%) and 20 were female (44%), and they were aged between 1 day and 16 years 6 months at the time of the original tracheostomy operation. 33 attempts were successful (58%). 10 children had more than one attempt at decannulation. Children were found to fail at every stage of the protocol, with the commonest point of failure being day 2 when the tracheostomy tube was capped.
    Discussion: We have demonstrated that our current protocol for ward decannulation is effective and safe, and that all five days of the protocol are required.
    MeSH term(s) Adolescent ; Child ; Child, Preschool ; Clinical Protocols ; Device Removal/methods ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Retrospective Studies ; Scotland ; Tracheostomy
    Language English
    Publishing date 2016-11
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 754501-0
    ISSN 1872-8464 ; 0165-5876
    ISSN (online) 1872-8464
    ISSN 0165-5876
    DOI 10.1016/j.ijporl.2016.07.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Management of congenital cartilaginous sleeve trachea in children.

    Hamilton, Jane / Clement, W Andrew / Kubba, Haytham

    International journal of pediatric otorhinolaryngology

    2014  Volume 78, Issue 11, Page(s) 2011–2014

    Abstract: Aims: Children with congenital tracheal cartilaginous sleeve may present to otolaryngology services with airway problems. We wish to describe our overall management in a series of four children with this very rare anomaly.: Methods: Retrospective ... ...

    Abstract Aims: Children with congenital tracheal cartilaginous sleeve may present to otolaryngology services with airway problems. We wish to describe our overall management in a series of four children with this very rare anomaly.
    Methods: Retrospective case note review of children diagnosed with congenital tracheal cartilaginous sleeve presenting to our department between 2006 and 2014.
    Results: Four patients were seen. One had Opitz G syndrome, two had Pfeiffers syndrome and one had no associated anomalies. Two children were successfully managed with laryngeal reconstruction using an anterior costal cartilage graft, while the third and fourth required a short period of tracheostomy only. All four are well and currently asymptomatic from an airway point of view.
    Conclusion: Congenital tracheal cartilaginous sleeve is a very rare and potentially challenging problem. Otolaryngologists should be aware that it can occur in children with syndromes other than craniosynostosis (and indeed, those with no syndrome) and that it can be successfully treated using established airway management techniques.
    Ethical approval: Registered with Clinical Governance Committee.
    MeSH term(s) Acrocephalosyndactylia/diagnosis ; Cartilage/abnormalities ; Cartilage/surgery ; Child ; Esophagus/abnormalities ; Female ; Humans ; Hypertelorism/diagnosis ; Hypospadias/diagnosis ; Infant ; Laryngoplasty ; Male ; Retrospective Studies ; Trachea/abnormalities ; Trachea/surgery ; Tracheostomy
    Language English
    Publishing date 2014-11
    Publishing country Ireland
    Document type Case Reports ; Journal Article
    ZDB-ID 754501-0
    ISSN 1872-8464 ; 0165-5876
    ISSN (online) 1872-8464
    ISSN 0165-5876
    DOI 10.1016/j.ijporl.2014.08.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Otolaryngological presentations of Cornelia de Lange syndrome.

    Hamilton, Jane / Clement, W Andrew / Kubba, Haytham

    International journal of pediatric otorhinolaryngology

    2014  Volume 78, Issue 9, Page(s) 1548–1550

    Abstract: Aim: Children with Cornelia de Lange syndrome frequently present to otolaryngology services with hearing problems. Airway problems have not previously been reported. We wish to describe our experience of the overall management in a series of children ... ...

    Abstract Aim: Children with Cornelia de Lange syndrome frequently present to otolaryngology services with hearing problems. Airway problems have not previously been reported. We wish to describe our experience of the overall management in a series of children with Cornelia de Lange syndrome.
    Methods: Retrospective case note review of children diagnosed with Cornelia de Lange syndrome presenting to our department between 2005 and 2014.
    Results: Six patients were seen. Airway problems consisted of laryngeal overspill with severe gastroesophageal dysmotility and reflux despite structurally normal airway (1 case), laryngomalacia requiring supraglottoplasty (2 cases), reflux laryngitis with secondary laryngomalacia and coincidental tracheal diverticulum (1 case) choanal atresia requiring stents (1 case) and obstructive sleep apnoea (1 case). Supraglottoplasty produced a dramatic improvement in feeding and breathing in both children who underwent the procedure. Two children had palatal anomalies and one underwent cochlear implantation for a profound sensorineural hearing loss.
    Conclusion: Children with Cornelia de Lange syndrome have multifaceted ENT problems. Airway pathology has not previously been described in Cornelia de Lange syndrome but has been common in our experience. We wish to highlight that laryngomalacia in Cornelia de Lange syndrome responds well to supraglottoplasty.
    MeSH term(s) Child, Preschool ; De Lange Syndrome/diagnosis ; De Lange Syndrome/surgery ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Otolaryngology ; Retrospective Studies ; Young Adult
    Language English
    Publishing date 2014-09
    Publishing country Ireland
    Document type Case Reports ; Journal Article
    ZDB-ID 754501-0
    ISSN 1872-8464 ; 0165-5876
    ISSN (online) 1872-8464
    ISSN 0165-5876
    DOI 10.1016/j.ijporl.2014.05.032
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The management of laryngeal clefts.

    Thiel, Gundula / Clement, W Andrew / Kubba, Haytham

    International journal of pediatric otorhinolaryngology

    2011  Volume 75, Issue 12, Page(s) 1525–1528

    Abstract: Objective: To review the clinical presentation and management of all infants and children presenting with laryngeal clefts to a tertiary pediatric ENT centre and to identify changes in practice over time.: Patients and methods: A retrospective case ... ...

    Abstract Objective: To review the clinical presentation and management of all infants and children presenting with laryngeal clefts to a tertiary pediatric ENT centre and to identify changes in practice over time.
    Patients and methods: A retrospective case note review of the management of all infants and children with a diagnosis of a laryngeal cleft identified in our Department between 01/11/2003 and 31/12/2010.
    Results: Twelve children with laryngeal clefts were identified. Six clefts were grade 1, five grade 2 and one grade 3b. All grade 1 clefts were managed conservatively. Of the grade 2 clefts, four required surgery with one being managed conservatively. Two were repaired using an open technique and two using an endoscopic technique. The grade 3b cleft was repaired endoscopically. Two cleft repairs broke down post-operatively requiring further surgery.
    Conclusions: Conservative management remains the management of choice for lower grade clefts. Where a laryngeal cleft requires repair there has been a trend towards the endoscopic over open technique, even of more extensive clefts.
    MeSH term(s) Child ; Child, Preschool ; Congenital Abnormalities/surgery ; Congenital Abnormalities/therapy ; Female ; Humans ; Infant ; Infant, Newborn ; Laryngoscopy ; Larynx/abnormalities ; Larynx/surgery ; Male ; Reoperation ; Retrospective Studies
    Language English
    Publishing date 2011-12
    Publishing country Ireland
    Document type Journal Article
    ZDB-ID 754501-0
    ISSN 1872-8464 ; 0165-5876
    ISSN (online) 1872-8464
    ISSN 0165-5876
    DOI 10.1016/j.ijporl.2011.08.020
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Laser division of congenital complete tracheal rings.

    Blackmore, Kate / Kubba, Haytham / Clement, W Andrew

    International journal of pediatric otorhinolaryngology

    2010  Volume 74, Issue 11, Page(s) 1327–1330

    Abstract: Congenital complete tracheal rings are a rare and life threatening problem in young children and they are often challenging to manage. Whilst historically associated with high mortality rates increasing experience with this tracheal pathology has led to ... ...

    Abstract Congenital complete tracheal rings are a rare and life threatening problem in young children and they are often challenging to manage. Whilst historically associated with high mortality rates increasing experience with this tracheal pathology has led to much improved survival rates and slide tracheoplasty has become the treatment of choice. We present 3 cases in which an open procedure was not deemed possible and they underwent laser division (CO2, KTP) of their complete rings. Two patients subsequently required stent insertion. All patients are alive and well at a mean follow up of 3 years and 5 months. Whilst laser division of complete tracheal rings has only been described in a small number of cases it may provide an alternative approach in patients who are not able to undergo an open procedure or in an emergency situation.
    MeSH term(s) Bronchoscopy ; Humans ; Infant ; Laryngoscopy ; Laser Therapy ; Lasers, Gas ; Lasers, Solid-State ; Male ; Stents ; Trachea/abnormalities ; Tracheal Stenosis/congenital ; Tracheal Stenosis/diagnosis ; Tracheal Stenosis/surgery
    Language English
    Publishing date 2010-11
    Publishing country Ireland
    Document type Case Reports ; Journal Article
    ZDB-ID 754501-0
    ISSN 1872-8464 ; 0165-5876
    ISSN (online) 1872-8464
    ISSN 0165-5876
    DOI 10.1016/j.ijporl.2010.07.019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Implementation by Scottish otolaryngologists of the Scottish Intercollegiate Guidelines Network document Management of Sore Throats and the Indications for Tonsillectomy: four years on.

    Clement, W Andrew / Dempster, John H

    The Journal of laryngology and otology

    2004  Volume 118, Issue 5, Page(s) 357–361

    Abstract: A postal survey was undertaken to assess otolaryngologists' awareness, implementation and perceived weaknesses of the Scottish Intercollegiate Guidelines Network (SIGN) clinical guideline for the Management of Sore Throat and Indications for ... ...

    Abstract A postal survey was undertaken to assess otolaryngologists' awareness, implementation and perceived weaknesses of the Scottish Intercollegiate Guidelines Network (SIGN) clinical guideline for the Management of Sore Throat and Indications for Tonsillectomy. The reply rate was 77 per cent. There was high awareness of the guideline and while 84 per cent of the correspondents felt that they followed the guideline, or a guideline based on it, only 35 per cent were able to accurately recall the four main criteria recommended for listing for tonsillectomy. Twenty-five per cent of the surgeons were in departments that had ongoing implementation programmes for these guidelines but only 10 per cent of surgeons were in departments that had audited their compliance. The most common criticism of the guideline (22 per cent) was that it failed to consider the impact of the disease process on the patient's quality of life. Suggestions made to improve the guideline are included.
    MeSH term(s) Guideline Adherence/statistics & numerical data ; Humans ; Medical Audit/methods ; Otolaryngology ; Patient Selection ; Practice Guidelines as Topic ; Scotland ; Surveys and Questionnaires ; Tonsillectomy
    Language English
    Publishing date 2004-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 218299-3
    ISSN 1748-5460 ; 0022-2151
    ISSN (online) 1748-5460
    ISSN 0022-2151
    DOI 10.1258/002221504323086543
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Liquid detergent capsule ingestion in children: an increasing trend.

    Fraser, Lyndsay / Wynne, David / Clement, W Andrew / Davidson, Mark / Kubba, Haytham

    Archives of disease in childhood

    2012  Volume 97, Issue 11, Page(s) 1007

    MeSH term(s) Capsules ; Caustics/poisoning ; Child, Preschool ; Detergents/poisoning ; Endoscopes, Gastrointestinal ; Humans ; Infant ; Larynx/injuries ; Pharynx/injuries
    Chemical Substances Capsules ; Caustics ; Detergents
    Language English
    Publishing date 2012-11
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 524-1
    ISSN 1468-2044 ; 0003-9888 ; 1359-2998
    ISSN (online) 1468-2044
    ISSN 0003-9888 ; 1359-2998
    DOI 10.1136/archdischild-2012-302662
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Endoscopic carbon dioxide laser division of congenital complete tracheal rings: a new operative technique.

    Clement, W Andrew / Geddes, Neil K / Best, Crispin

    The Annals of thoracic surgery

    2005  Volume 79, Issue 2, Page(s) 687–689

    Abstract: A carbon dioxide laser was used through a bronchoscope to split the posterior aspect of complete tracheal rings in the distal trachea of a 16-month-old boy previously palliated for cyanotic congenital heart disease. After laser division of the complete ... ...

    Abstract A carbon dioxide laser was used through a bronchoscope to split the posterior aspect of complete tracheal rings in the distal trachea of a 16-month-old boy previously palliated for cyanotic congenital heart disease. After laser division of the complete tracheal rings, the patient was successfully extubated. Subsequently, the boy had granulation tissue develop, which required bronchoscopic resection, and then severe posterior tracheal impingement developed from the esophageal herniation, which required placement of a distal tracheal stent. Although unsuccessful in this case, carbon dioxide laser division of complete tracheal rings may be a safe and effective method of treating congenital tracheal stenosis in selected cases.
    MeSH term(s) Abnormalities, Multiple/diagnosis ; Abnormalities, Multiple/surgery ; Bronchoscopy/methods ; Heart Septal Defects/diagnosis ; Heart Septal Defects/surgery ; Humans ; Infant ; Laser Therapy/methods ; Male ; Pulmonary Atresia/diagnosis ; Pulmonary Atresia/surgery ; Trachea/abnormalities ; Trachea/surgery
    Language English
    Publishing date 2005-02
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 211007-6
    ISSN 1552-6259 ; 0003-4975
    ISSN (online) 1552-6259
    ISSN 0003-4975
    DOI 10.1016/j.athoracsur.2003.09.105
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Laser epiglottopexy for laryngomalacia: 10 years' experience in the west of Scotland.

    Whymark, Andrew D / Clement, W Andrew / Kubba, Haytham / Geddes, Neil K

    Archives of otolaryngology--head & neck surgery

    2006  Volume 132, Issue 9, Page(s) 978–982

    Abstract: Objectives: To determine the results of laser epiglottopexy and to compare them with other surgical techniques for severe laryngomalacia.: Design: A retrospective 10-year case note review of laser epiglottopexy for severe laryngomalacia.: Setting: ...

    Abstract Objectives: To determine the results of laser epiglottopexy and to compare them with other surgical techniques for severe laryngomalacia.
    Design: A retrospective 10-year case note review of laser epiglottopexy for severe laryngomalacia.
    Setting: Royal Hospital for Sick Children, Glasgow, Scotland.
    Patients: The study population comprised 52 male and 24 female children who underwent surgery for laryngomalacia between January 1, 1993, and December 31, 2002. In all children except 2, the indication for surgery was stridor associated with poor feeding and failure to thrive. The age at presentation ranged from 5 days to 32 months (mean, 16 weeks). Three had neurological problems, in 3 a syndrome was diagnosed, and 2 were described as dysmorphic and no syndrome was diagnosed; 5 had a cardiac abnormality. Complete follow-up data were available for 59 children (78%). Intervention Laser epiglottopexy.
    Main outcome measure: Resolution of stridor and growth velocity.
    Results: Resolution of stridor was complete in 34 children, with mild residual stridor in 4 and persistent stridor but good weight gain in 5 (73% improved sufficiently with 1 procedure). Improvement was documented objectively by measuring growth velocity. Two children required a brief period of intubation postoperatively, and 4 had postoperative respiratory tract infections. Seven children (12%) required revision endoscopic laser surgery to control symptoms. There were no cases of supraglottic stenosis. One child died of cardiac abnormalities, and 8 (14%) required a tracheostomy, of whom 6 had neurological or syndromal abnormalities and 2 had associated tracheomalacia.
    Conclusions: We describe a technique of laser epiglottopexy for laryngomalacia and present objective evidence of its efficacy by means of growth velocity charts in a retrospective review of laryngomalacia surgery over a 10-year period. We believe this to be a safe method for treating a self-limiting condition. We have had comparable success to other surgical techniques without having the risks of permanent scarring to the supraglottis.
    MeSH term(s) Child, Preschool ; Epiglottis/surgery ; Female ; Humans ; Infant ; Infant, Newborn ; Laryngeal Diseases/surgery ; Laser Therapy ; Male
    Language English
    Publishing date 2006-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632721-7
    ISSN 1538-361X ; 0886-4470 ; 2168-6181
    ISSN (online) 1538-361X
    ISSN 0886-4470 ; 2168-6181
    DOI 10.1001/archotol.132.9.978
    Database MEDical Literature Analysis and Retrieval System OnLINE

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