Article ; Online: Season, weather and predictors of healthcare-associated Gram-negative bloodstream infections: a case-only study.
The Journal of hospital infection
2018 Volume 101, Issue 2, Page(s) 134–141
Abstract: Background: Recent studies reported seasonality in healthcare-associated infections (HCAI). The association of this phenomenon with other risk factors for HCAI is not clear.: Aim: To analyse the interplay of season, weather and usual predictors of ... ...
| Abstract | Background: Recent studies reported seasonality in healthcare-associated infections (HCAI). The association of this phenomenon with other risk factors for HCAI is not clear. Aim: To analyse the interplay of season, weather and usual predictors of healthcare-associated bloodstream infections caused by Gram-negative bacilli (GNB-BSI). Methods: A case-only study was conducted in a teaching hospital in Brazil. The study enrolled 446 subjects with GNB-BSI diagnosed from July 2012 to June 2016. Demographic data, comorbidities, invasive procedures and use of antimicrobials were reviewed in medical charts. The season in which GNB-BSI occurred, and weather parameters on the day of diagnosis were recorded. Factors associated with occurrence of GNB-BSI in different seasons (reference category: winter) and caused by different GNB (reference category: Escherichia coli) were analysed. Uni- and multi-variable models of multi-nomial logistic regression were used for analysis. Findings: GNB-BSI diagnosed in summer was more likely to be caused by Klebsiella spp. [odds ratio (OR) 5.33; 95% confidence interval (CI) 2.04-13.96] or Acinetobacter baumannii (OR 2.69; 95% CI 1.04-6.96), and there was an association between Klebsiella spp. and spring (OR 2.86; 95% CI 1.14-7.18). Average temperature on the day of diagnosis was associated with Klebsiella spp. (OR 1.19; 95% CI 1.07-1.33) and A. baumannii (OR 1.20; 95% CI 1.07-1.34). Conclusion: Warm seasons and daily temperature impact on the aetiology of GNB-BSI, even in models adjusted for usual risk factors. One possible explanation for these findings is that seasonality of healthcare-associated pathogens is intrinsic to micro-organisms, and not associated with comorbidities, procedures or use of antimicrobials. |
|||||
|---|---|---|---|---|---|---|
| MeSH term(s) | Adolescent ; Adult ; Aged ; Aged, 80 and over ; Bacteremia/epidemiology ; Brazil/epidemiology ; Cross Infection/epidemiology ; Female ; Gram-Negative Bacterial Infections/epidemiology ; Hospitals, Teaching ; Humans ; Male ; Middle Aged ; Models, Statistical ; Risk Factors ; Seasons ; Weather ; Young Adult | |||||
| Language | English | |||||
| Publishing date | 2018-06-22 | |||||
| Publishing country | England | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 779366-2 | |||||
| ISSN | 1532-2939 ; 0195-6701 | |||||
| ISSN (online) | 1532-2939 | |||||
| ISSN | 0195-6701 | |||||
| DOI | 10.1016/j.jhin.2018.06.015 | |||||
| Shelf mark |
|
|||||
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
In stock of ZB MED Cologne/Königswinter
| Zs.A 1586: Show issues | Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG) |
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.