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Article: Nutrition modeling in the Lives Saved Tool (LiST)

Clermont, Adrienne

The journal of nutrition volume 147, number 11S (November 2017), Seite 2129-2203

2017

Author's details	supplement coordinator: Adrienne Clermont
Collection	The journal of nutrition
Language	English
Publishing place	Rockville, Md., [2017]
Publishing country	United States
Document type	Article
HBZ-ID	HT019534713
Database	Catalogue ZB MED Nutrition, Environment, Agriculture

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Article ; Online: The impact of eliminating within-country inequality in health coverage on maternal and child mortality: a Lives Saved Tool analysis.

Clermont, Adrienne

BMC public health

2017 Volume 17, Issue Suppl 4, Page(s) 734

Abstract: Background: Inequality in healthcare across population groups in low-income countries is a growing topic of interest in global health. The Lives Saved Tool (LiST), which uses health intervention coverage to model maternal, neonatal, and child health ... ...

Abstract	Background: Inequality in healthcare across population groups in low-income countries is a growing topic of interest in global health. The Lives Saved Tool (LiST), which uses health intervention coverage to model maternal, neonatal, and child health outcomes such as mortality rates, can be used to analyze the impact of within-country inequality. Methods: Data from nationally representative household surveys (98 surveys conducted between 1998 and 2014), disaggregated by wealth quintile, were used to create a LiST analysis that models the impact of scaling up health intervention coverage for the entire country from the national average to the rate of the top wealth quintile (richest 20% of the population). Interventions for which household survey data are available were used as proxies for other interventions that are not measured in surveys, based on co-delivery of intervention packages. Results: For the 98 countries included in the analysis, 24-32% of child deaths (including 34-47% of neonatal deaths and 16-19% of post-neonatal deaths) could be prevented by scaling up national coverage of key health interventions to the level of the top wealth quintile. On average, the interventions with most unequal coverage rates across wealth quintiles were those related to childbirth in health facilities and to water and sanitation infrastructure; the most equally distributed were those delivered through community-based mass campaigns, such as vaccines, vitamin A supplementation, and bednet distribution. Conclusions: LiST is a powerful tool for exploring the policy and programmatic implications of within-country inequality in low-income, high-mortality-burden countries. An "Equity Tool" app has been developed within the software to make this type of analysis easily accessible to users.
Language	English
Publishing date	2017-11-07
Publishing country	England
Document type	Journal Article
ISSN	1471-2458
ISSN (online)	1471-2458
DOI	10.1186/s12889-017-4737-2
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Nutrition Interventions in the Lives Saved Tool (LiST).

Clermont, Adrienne / Walker, Neff

The Journal of nutrition

2017 Volume 147, Issue 11, Page(s) 2132S–2140S

Abstract: The Lives Saved Tool (LiST) was initially developed in 2003 to estimate the impact of increasing coverage of efficacious interventions on under-5 mortality. Over time, the model has been expanded to include more outcomes (neonatal mortality, maternal ... ...

Abstract	The Lives Saved Tool (LiST) was initially developed in 2003 to estimate the impact of increasing coverage of efficacious interventions on under-5 mortality. Over time, the model has been expanded to include more outcomes (neonatal mortality, maternal mortality, stillbirths) and interventions. The model has also added risk factors, such as stunting and wasting, and over time has attempted to capture a full range of nutrition and nutrition-related interventions (e.g., antenatal supplementation, breastfeeding promotion, child supplemental feeding, acute malnutrition treatment), practices (e.g., age-appropriate breastfeeding), and outcomes (e.g., stunting, wasting, birth outcomes, maternal anemia). This article reviews the overall nutrition-related structure, assumptions, and outputs that are currently available in LiST. This review focuses on the new assumptions and structure that have been added to the model as part of the current effort to expand and improve the nutrition modeling capability of LiST. It presents the full set of linkages in the model that relate to nutrition outcomes, as well as the research literature used to support those linkages.
MeSH term(s)	Anemia, Iron-Deficiency/diet therapy ; Anemia, Iron-Deficiency/prevention & control ; Breast Feeding ; Child ; Child Mortality ; Family Planning Services ; Female ; Growth Disorders/diet therapy ; Growth Disorders/prevention & control ; Humans ; Infant ; Infant Mortality ; Maternal Mortality ; Meta-Analysis as Topic ; Models, Theoretical ; Mothers ; Nutrition Therapy/methods ; Nutritional Physiological Phenomena ; Nutritional Status ; Stillbirth ; Wasting Syndrome/diet therapy ; Wasting Syndrome/prevention & control
Language	English
Publishing date	2017-09-13
Publishing country	United States
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	218373-0
ISSN	1541-6100 ; 0022-3166
ISSN (online)	1541-6100
ISSN	0022-3166
DOI	10.3945/jn.116.243766
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Electroconvulsive therapy in an adolescent patient with catatonia: a case report.

Clermont, Adrienne / Loubriel, Daphne / Li, Erin / Mitera, Darlene / Samuels, Susan

Neurocase

2020 Volume 27, Issue 1, Page(s) 18–21

Abstract: Catatonia is characterized by motor and behavioral symptoms and can arise in a wide variety of medical and psychiatric conditions. We describe the case of a 16-year-old female with a history of anxiety and depression who presented with prominent symptoms ...

Abstract	Catatonia is characterized by motor and behavioral symptoms and can arise in a wide variety of medical and psychiatric conditions. We describe the case of a 16-year-old female with a history of anxiety and depression who presented with prominent symptoms of negativism, initially diagnosed as conversion disorder. She failed to respond to increasing doses of benzodiazepines; after over six weeks of hospitalization, she received electroconvulsive therapy (ECT), resulting in significant remission of symptoms. This case demonstrates the importance of prompt diagnosis and treatment of catatonia in adolescent patients, as well as the safety and efficacy of ECT in this population.
MeSH term(s)	Adolescent ; Benzodiazepines/therapeutic use ; Bipolar Disorder/complications ; Bipolar Disorder/therapy ; Catatonia/complications ; Catatonia/therapy ; Child ; Electroconvulsive Therapy ; Female ; Humans
Chemical Substances	Benzodiazepines (12794-10-4)
Language	English
Publishing date	2020-12-09
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	1302651-3
ISSN	1465-3656 ; 1355-4794
ISSN (online)	1465-3656
ISSN	1355-4794
DOI	10.1080/13554794.2020.1859545
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Effects of deworming on child and maternal health: a literature review and meta-analysis.

Thayer, Winter Maxwell / Clermont, Adrienne / Walker, Neff

BMC public health

2017 Volume 17, Issue Suppl 4, Page(s) 830

Abstract: Background: Soil-transmitted helminth infections are widespread. Many studies have been published on the topic of deworming. The Lives Saved Tool (LiST) is a software package that uses a deterministic mathematical model to estimate the effect of scaling ...

Abstract	Background: Soil-transmitted helminth infections are widespread. Many studies have been published on the topic of deworming. The Lives Saved Tool (LiST) is a software package that uses a deterministic mathematical model to estimate the effect of scaling up interventions on maternal and child health outcomes. This review investigates the scope of available evidence for benefits of deworming treatments in order to inform a decision about possible inclusion of deworming as an intervention in LiST. Methods: We searched PubMed, the Cochrane Library, and Google Scholar. We included studies that reported pre/post data in children younger than 5 years or pregnant women for outcomes related to mortality and growth. We excluded studies that compared different anthelminthic treatments but did not include a placebo or non-treatment group, and those that did not report post-intervention outcomes. We categorized articles by treated population (children younger than 5 years and pregnant women), experimental versus observational, mass drug administration (MDA) versus treatment, and reported outcome. Results: We identified 58 relevant trials; 27 investigated children younger than 5 years and 11 investigated pregnant women; one reported on both children younger than 5 years and pregnant women. We conducted meta-analyses of relevant outcomes in children younger than 5 years. Conclusions: Deworming did not show consistent benefits for indicators of mortality, anemia, or growth in children younger than five or women of reproductive age. We do not recommend including the effect of deworming in the LiST model.
MeSH term(s)	Anthelmintics/therapeutic use ; Child Health/statistics & numerical data ; Child, Preschool ; Female ; Humans ; Infant ; Infant, Newborn ; Maternal Health/statistics & numerical data ; Pregnancy ; Randomized Controlled Trials as Topic
Chemical Substances	Anthelmintics
Language	English
Publishing date	2017-11-07
Publishing country	England
Document type	Journal Article ; Meta-Analysis ; Review
ISSN	1471-2458
ISSN (online)	1471-2458
DOI	10.1186/s12889-017-4747-0
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: New Option in the Lives Saved Tool (LiST) Allows for the Conversion of Prevalence of Small-for-Gestational-Age and Preterm Births to Prevalence of Low Birth Weight.

Kozuki, Naoko / Katz, Joanne / Clermont, Adrienne / Walker, Neff

The Journal of nutrition

2017 Volume 147, Issue 11, Page(s) 2141S–2146S

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Africa South of the Sahara/epidemiology ; Asia/epidemiology ; Birth Weight ; Child Development ; Child Health ; Developing Countries ; Humans ; Infant ; Infant Mortality ; Infant, Low Birth Weight ; Infant, Small for Gestational Age ; Latin America/epidemiology ; Models, Theoretical ; Premature Birth/epidemiology ; Premature Birth/prevention & control ; Prevalence ; Software
Language	English
Publishing date	2017-09-13
Publishing country	United States
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	218373-0
ISSN	1541-6100 ; 0022-3166
ISSN (online)	1541-6100
ISSN	0022-3166
DOI	10.3945/jn.117.247767
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: The Lives Saved Tool (LiST) as a Model for Prevention of Anemia in Women of Reproductive Age.

Heidkamp, Rebecca / Guida, Renee / Phillips, Erica / Clermont, Adrienne

The Journal of nutrition

2017 Volume 147, Issue 11, Page(s) 2156S–2162S

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Adolescent ; Adult ; Anemia, Iron-Deficiency/epidemiology ; Anemia, Iron-Deficiency/prevention & control ; Dietary Supplements ; Female ; Food, Fortified ; Humans ; Micronutrients/administration & dosage ; Micronutrients/blood ; Micronutrients/deficiency ; Middle Aged ; Models, Theoretical ; Pregnancy ; Pregnancy Complications, Hematologic/epidemiology ; Pregnancy Complications, Hematologic/prevention & control ; Prevalence ; Randomized Controlled Trials as Topic ; Young Adult
Chemical Substances	Micronutrients
Language	English
Publishing date	2017-09-13
Publishing country	United States
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	218373-0
ISSN	1541-6100 ; 0022-3166
ISSN (online)	1541-6100
ISSN	0022-3166
DOI	10.3945/jn.117.252429
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Article ; Online: Modeling the Impact of Nutrition Interventions on Birth Outcomes in the Lives Saved Tool (LiST).

Heidkamp, Rebecca / Clermont, Adrienne / Phillips, Erica

The Journal of nutrition

2017 Volume 147, Issue 11, Page(s) 2188S–2193S

Abstract: Background: ...

Abstract	Background:
MeSH term(s)	Anemia, Iron-Deficiency/diet therapy ; Anemia, Iron-Deficiency/prevention & control ; Dietary Supplements ; Evidence-Based Medicine ; Female ; Humans ; Infant ; Infant, Newborn ; Infant, Small for Gestational Age ; Micronutrients/administration & dosage ; Models, Theoretical ; Nutrition Therapy ; Pregnancy ; Premature Birth/diet therapy ; Premature Birth/prevention & control ; Randomized Controlled Trials as Topic ; Risk Factors
Chemical Substances	Micronutrients
Language	English
Publishing date	2017-09-13
Publishing country	United States
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	218373-0
ISSN	1541-6100 ; 0022-3166
ISSN (online)	1541-6100
ISSN	0022-3166
DOI	10.3945/jn.116.243667
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Prevalence and Severity of Chronic Kidney Disease in Haiti.

Roberts, Nicholas L S / Pierre, Jean L / Rouzier, Vanessa / Sufra, Rodney / St-Preux, Stefano / Yan, Lily D / Metz, Miranda / Clermont, Adrienne / Apollon, Alexandra / Sabwa, Shalom / Deschamps, Marie M / Kingery, Justin R / Peck, Robert / Fitzgerald, Daniel / Pape, Jean W / Tummalapalli, Sri Lekha / McNairy, Margaret L

Clinical journal of the American Society of Nephrology : CJASN

2023 Volume 18, Issue 6, Page(s) 739–747

Abstract: Background: CKD is a major cause of morbidity and mortality in lower-income countries. However, population-based studies characterizing the epidemiology of CKD in these settings are lacking. The study objective was to describe the epidemiology of CKD in ...

Abstract	Background: CKD is a major cause of morbidity and mortality in lower-income countries. However, population-based studies characterizing the epidemiology of CKD in these settings are lacking. The study objective was to describe the epidemiology of CKD in a population-based cohort in urban Haiti, including estimates of the prevalence by CKD stage, the magnitude of associated factors with CKD, and the proportion on guideline-recommended treatment. Methods: We assessed the prevalence of CKD and associated risk factors in the population-based Haiti Cardiovascular Disease Cohort. We analyzed cross-sectional data from 2424 adults who completed a clinical examination, risk factor surveys, and laboratory measurements for serum creatinine, urinary albumin, and urinary creatinine. We compared our results with US estimates from the National Health and Nutrition Examination Survey. CKD was defined as either a reduced eGFR <60 ml/min per 1.73 m 2 or urinary albumin-to-creatinine ratio ≥30 mg/g according to the Kidney Disease Improving Global Outcomes guidelines. Multivariable logistic regression identified associated factors with CKD. Results: The mean age was 42 years, 57% of participants were female, and 69% lived in extreme poverty on ≤1 US dollar per day. The age-standardized prevalence of CKD was 14% (95% confidence interval [CI], 12% to 15%). The age-standardized prevalence of reduced eGFR and elevated urinary albumin-to-creatinine ratio was 3% (95% CI, 2% to 4%) and 11% (95% CI, 10% to 13%), respectively. Diabetes (adjusted odds ratio, 4.1; 95% CI, 2.7 to 6.2) and hypertension (adjusted odds ratio, 2.9; 95% CI, 2.0 to 4.2) were significantly associated with CKD. Only 12% of participants with CKD and albuminuria were on guideline-recommended agents, such as angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers. Conclusions: In a large population-based cohort of Haitian adults, CKD was highly associated with both diabetes and hypertension. The proportion of participants with CKD on treatment was low, underscoring the need for strengthening clinical management and nephrology care health infrastructure in Haiti. Clinical trial registry name and registration number: A Longitudinal Cohort Study to Evaluate Cardiovascular Risk Factors and Disease in Haiti, NCT03892265 .
MeSH term(s)	Adult ; Humans ; Female ; Male ; Haiti/epidemiology ; Prevalence ; Creatinine ; Nutrition Surveys ; Longitudinal Studies ; Cross-Sectional Studies ; Glomerular Filtration Rate ; Renal Insufficiency, Chronic/diagnosis ; Renal Insufficiency, Chronic/epidemiology ; Renal Insufficiency, Chronic/complications ; Diabetes Mellitus/epidemiology ; Risk Factors ; Hypertension/epidemiology ; Hypertension/complications ; Albumins ; Albuminuria/urine
Chemical Substances	Creatinine (AYI8EX34EU) ; Albumins
Language	English
Publishing date	2023-04-18
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	2226665-3
ISSN	1555-905X ; 1555-9041
ISSN (online)	1555-905X
ISSN	1555-9041
DOI	10.2215/CJN.0000000000000175
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Article ; Online: Impacts of micronutrient intervention programs on effective coverage and lives saved: Modeled evidence from Cameroon.

Vosti, Stephen A / Adams, Katherine P / Michuda, Aleksandr / Ortiz-Becerra, Karen / Luo, Hanqi / Haile, Demewoz / Chou, Victoria B / Clermont, Adrienne / Teta, Ismael / Ndjebayi, Alex / Kagin, Justin / Guintang, Jules / Engle-Stone, Reina

Annals of the New York Academy of Sciences

2022 Volume 1519, Issue 1, Page(s) 199–210

Abstract: Policymakers are committed to improving nutritional status and to saving lives. Some micronutrient intervention programs (MIPs) can do both, but not to the same degrees. We apply the Micronutrient Intervention Modeling tool to compare sets of MIPs for (1) ...

Abstract	Policymakers are committed to improving nutritional status and to saving lives. Some micronutrient intervention programs (MIPs) can do both, but not to the same degrees. We apply the Micronutrient Intervention Modeling tool to compare sets of MIPs for (1) achieving dietary adequacy separately for zinc, vitamin A (VA), and folate for children and women of reproductive age (WRA), and (2) saving children's lives via combinations of MIPs. We used 24-h dietary recall data from Cameroon to estimate usual intake distributions of zinc and VA for children 6-59 months and of folate for WRA. We simulated the effects on dietary inadequacy and lives saved of four fortified foods and two VA supplementation (VAS) platforms. We estimated program costs over 10 years. To promote micronutrient-specific dietary adequacy, the economic optimization model (EOM) selected zinc- and folic acid-fortified wheat flour, VA-fortified edible oils, and bouillon cubes, and VAS via Child Health Days in the North macroregion. A different set of cost-effective MIPs emerged for reducing child mortality, shifting away from VA and toward more zinc for children and more folic acid for WRA. The EOM identified more efficient sets of MIPs than the business-as-usual MIPs, especially among programs aiming to save lives.
MeSH term(s)	Child ; Humans ; Female ; Micronutrients ; Flour ; Cameroon ; Triticum ; Diet ; Vitamin A ; Food, Fortified ; Folic Acid ; Zinc
Chemical Substances	Micronutrients ; Vitamin A (11103-57-4) ; Folic Acid (935E97BOY8) ; Zinc (J41CSQ7QDS)
Language	English
Publishing date	2022-12-05
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	211003-9
ISSN	1749-6632 ; 0077-8923
ISSN (online)	1749-6632
ISSN	0077-8923
DOI	10.1111/nyas.14937
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