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Article: First histological findings in rabbit model of peritoneal dialysis

Stojimirović, B., Clinical Center of Serbia, Belgrade (Serbia) / Jovanović, N., Clinical Center of Serbia, Belgrade (Serbia) / Laušević, Z., Clinical Center of Serbia, Belgrade (Serbia) / Krstić, S., Clinical Center of Serbia, Belgrade (Serbia) / Obradović, M., University of Belgrade, Belgrade (Serbia). School of Medicine / Žunić-Božinovski, S., University of Belgrade, Belgrade (Serbia). School of Medicine

Acta Veterinaria (Serbia)

(2010) Volume v. 60, Issue (5-6), Page(s) p. 625–632

Abstract: Investigating peritoneal membrane alterations caused by peritoneal dialysis fluid during peritoneal dialysis in humans is still intriguing. That is why the study was aimed to provide rabbit peritoneal tissue samples suitable for histological analyses ... ...

Abstract	Investigating peritoneal membrane alterations caused by peritoneal dialysis fluid during peritoneal dialysis in humans is still intriguing. That is why the study was aimed to provide rabbit peritoneal tissue samples suitable for histological analyses using a modified non-uremic infusion model of peritoneal dialysis on rabbit. A double-lumen central venous catheter, surgically placed in the peritoneal cavity of adult Chincilla rabbit, was used for daily instillations of peritoneal dialysate. Peritoneal tissue samples were obtained during the catheter placement and removal and analysed by light and transmission electron microscopy. The results of histological examinations showed that this modified non-uremic rabbit model of peritoneal dialysis is suitable for obtaining peritoneal tissue samples for light and transmission electron microscopy examination, and can be used to analyse the effects of different dialysis solutions on rabbit peritoneal membrane.
Keywords	RABBITS ; PERITONEUM ; MEMBRANES ; DIALYSIS ; LAPIN (ORYCTOLAGUS) ; PERITOINE ; MEMBRANE ; DIALYSE ; CONEJO (ORYCTOLAGUS) ; PERITONEO ; MEMBRANA ; DIALISIS ; http://www.fao.org/aos/agrovoc#c_6414 ; http://www.fao.org/aos/agrovoc#c_5712 ; http://www.fao.org/aos/agrovoc#c_28457 ; http://www.fao.org/aos/agrovoc#c_2240
Language	English
Document type	Article
ISSN	0567-8315
Database	AGRIS - International Information System for the Agricultural Sciences and Technology

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Article: Effect of acute experimental aluminum poisoning on hematologic parameters

Milovanović, J., Faculty of Medicine, Belgrade (Serbia) / Milovanović, A., Faculty of Medicine, Belgrade (Serbia) / Milovanović, A., Clinical Center of Serbia, Belgrade (Serbia). Clinic for Rehabilitation / Ješić, S., Faculty of Medicine, Belgrade (Serbia) / Jotić, A., Clinical Center of Serbia, Belgrade (Serbia). Otorhinolaryngology and Maxillofacial Surgery Clinic / Čemerikić, D., Faculty of Medicine, Belgrade (Serbia) / Artiko, V., Faculty of Medicine, Belgrade (Serbia) / Petrović, M., Faculty of Medicine, Belgrade (Serbia) / Pavlović, B., Clinical Center of Serbia, Belgrade (Serbia). Otorhinolaryngology and Maxillofacial Surgery Clinic / Folić, M., Clinical Center of Serbia, Belgrade (Serbia). Otorhinolaryngology and Maxillofacial Surgery Clinic

Acta Veterinaria (Serbia)

(2012) Volume v. 62, Issue (2-3), Page(s) p. 183–192

Abstract: Having in mind the presence of aluminum in industry, as well as in households, we wanted to define changes in the number of erythrocytes and aluminum content in the plasma and erythrocytes following acute aluminum poisoning under experimental conditions. ...

Abstract	Having in mind the presence of aluminum in industry, as well as in households, we wanted to define changes in the number of erythrocytes and aluminum content in the plasma and erythrocytes following acute aluminum poisoning under experimental conditions. The experiment involved gerbils which received intraperitoneally aluminum chloride solution at a dose of 3.7g per kg of body mass. The experimental group was sacrificed after 24, 48, 72 and 96 hours from the beginning of the experiment by cardiac punction or by abdominal artery punction. The control group was treated with saline, only. The number of erythrocytes and hemoglobin concentration were considerably reduced with respect to the control group, most likely as the result of cell membrane changes and reduced life cycle of erythrocytes. During the experiment, aluminum content in the plasma was increased in the first and second day of the experiment, it started to decline on the third day, while on the fourth day it returned to its original value, which proves again the existence of a special mechanism of clearance of aluminum in plasma.
Keywords	MICE ; ALUMINIUM ; POISONING ; ERYTHROCYTES ; BLOOD PLASMA ; BLOOD ; SOURIS ; ALUMINIUM ; INTOXICATION ; ERYTHROCYTE ; PLASMA SANGUIN ; SANG ; RATAN ; ALUMINIO ; ENVENENAMIENTO ; ERITROCITOS ; PLASMA SANGUANEO ; SANGRE ; http://www.fao.org/aos/agrovoc#c_4795 ; http://www.fao.org/aos/agrovoc#c_317 ; http://www.fao.org/aos/agrovoc#c_6051 ; http://www.fao.org/aos/agrovoc#c_2659 ; http://www.fao.org/aos/agrovoc#c_9320 ; http://www.fao.org/aos/agrovoc#c_959
Language	English
Document type	Article
ISSN	0567-8315
Database	AGRIS - International Information System for the Agricultural Sciences and Technology

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Article: Effects of acute cadmium toxicity on oxidative damage in nervous tissue

Milovanovic, A. / Milovanovic, J., Clinical Center of Serbia, Belgrade (Serbia) / Cemerikic, D., Medical Faculty, Belgrade (Serbia). Institute for Pathophysiology / Novakovic, M., Medical Faculty, Foca (Bosnia and Herzegovina) / Petrovic, M., Clinical Center of Serbia, Belgrade (Serbia) / Jovanovic, A., Medical Faculty, Belgrade (Serbia) / Petronic, I., Clinical Center of Serbia, Belgrade (Serbia)

Acta Veterinaria (Serbia)

(2009) Volume v. 59, Issue (5-6), Page(s) p. 633–640

Abstract: We tested the hypothesis that acute cadmium exposure would lead to increased oxidative damage in various brain regions. Adult male rats were treated either with a single dose of 50 ppm of CdCl2 (LD50), or a single dose of 100 ppm CdCl2 (LD50), against ... ...

Abstract	We tested the hypothesis that acute cadmium exposure would lead to increased oxidative damage in various brain regions. Adult male rats were treated either with a single dose of 50 ppm of CdCl2 (LD50), or a single dose of 100 ppm CdCl2 (LD50), against control group not exposed to Cd. The enzymatic activity of total and mitochondrial SOD, as well as GR was significantly and dose-depending decreased, but MDA content was shown only a moderate increase. Results demonstrated the harmful effects of acute Cd exposure, in the nervous tissue, through mechanisms of oxidative damage.
Keywords	RATS ; MALES ; BRAIN ; CADMIUM ; TOXICITY ; OXIDATIVE STRESS ; FREE RADICALS ; RAT ; MALE ; ENCEPHALE ; CADMIUM ; TOXICITE ; STRESS OXYDATIF ; RADICAL LIBRE ; RATA ; MACHO ; CEREBRO ; CADMIO ; TOXICIDAD ; ESTRES OXIDATIVO ; RADICALES LIBRES ; http://www.fao.org/aos/agrovoc#c_6464 ; http://www.fao.org/aos/agrovoc#c_15995 ; http://www.fao.org/aos/agrovoc#c_1053 ; http://www.fao.org/aos/agrovoc#c_1178 ; http://www.fao.org/aos/agrovoc#c_7826 ; http://www.fao.org/aos/agrovoc#c_37481 ; http://www.fao.org/aos/agrovoc#c_33488
Language	English
Document type	Article
ISSN	0567-8315
Database	AGRIS - International Information System for the Agricultural Sciences and Technology

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Article: Rat skeletal muscle contractility: The role of beta-adrenoceptors and nitric oxide system

Prostran, M., Faculty of Medicine, Belgrade (Serbia) / Stojanović, R., Faculty of Medicine, Belgrade (Serbia) / Todorović Z., Faculty of Medicine, Belgrade (Serbia) / Vučković, S., Faculty of Medicine, Belgrade (Serbia) / Savić-Vujović, K., Faculty of Medicine, Belgrade (Serbia) / Medić, B., Faculty of Medicine, Belgrade (Serbia) / Grajić, M., Clinical Center of Serbia, Belgrade (Serbia). Clinic for Physical and Rehabilitation Medicine / Kadija, M., Clinical Center of Serbia, Belgrade (Serbia). Institute for Orthopaedic Surgery and Traumatology

Acta Veterinaria (Serbia)

(2011) Volume v. 61, Issue (4), Page(s) p. 339–348

Abstract: Both beta-adrenoceptors and the nitric oxide system play a significant role in the modulation of skeletal muscle contractility. Skeletal muscle adrenoceptors mainly belong to beta2 subtype, while all three types of nitric oxide synthase may influence ... ...

Abstract	Both beta-adrenoceptors and the nitric oxide system play a significant role in the modulation of skeletal muscle contractility. Skeletal muscle adrenoceptors mainly belong to beta2 subtype, while all three types of nitric oxide synthase may influence muscle contractility. The aim of our study was to investigate the possible interplay between beta-adrenoceptor agonists and nitric oxide system in the modulation of contractility of isolated rat hemidiaphragm. Adrenaline (0.05-1.5 micromol/L) and noradrenaline (1-5 micromol/L) given in a cumulative manner produced a concentration-related increase in Td. L-NAME (1, 3 and 10 mmol/L; 30 min of incubation) produced a significant, dose-dependent increase in Td of the muscle pretreated with cumulative concentrations of adrenaline (deltaTd up to 16%). When hemidiaphragm was pretreated with noradrenaline instead of adrenaline, L-NAME (3 mmol/L) it produced a similar potentiation of Td. In conclusion, nitric oxide seems to oppose beta-adrenoceptor potentiation of diaphragm contractility, and such an interaction depends on previous adrenoceptor stimulation. Nitric oxide probably decreases beta-adrenoceptor response via cGMP-induced stimulation of phosphodiesterase 2. The interaction between substances which modulate NO system activity and cAMP levels in the skeletal muscle may be of a great clinical importance for the treatment of certain respiratory and neurological diseases.
Keywords	RATS ; MUSCLES ; EPINEPHRINE ; HORMONE RECEPTORS ; RAT ; MUSCLE ; ADRANALINE ; RACEPTEUR D'HORMONE ; RATA ; MASCULOS ; EPINEFRINA ; RECEPTORES DE HORMONAS ; http://www.fao.org/aos/agrovoc#c_6464 ; http://www.fao.org/aos/agrovoc#c_5003 ; http://www.fao.org/aos/agrovoc#c_2620 ; http://www.fao.org/aos/agrovoc#c_26875
Language	English
Document type	Article
ISSN	0567-8315
Database	AGRIS - International Information System for the Agricultural Sciences and Technology

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Article: Characteristics of the antivasoconstrictor effect of pinacidil on isolated radial artery

Gojkovic-Bukarica, Lj., University of Belgrade, Belgrade (Serbia). Faculty of Medicine / Stojnic, N., University of Belgrade, Belgrade (Serbia). Faculty of Medicine / Peric, M., Institute for Cardiovascular Diseases Dedinje, Belgrade (Serbia) / Cvejic, J., University of Novi Sad, Novi Sad (Serbia). Faculty of Medicine / Bumbasirevic, M., Clinical Center of Serbia, Belgrade (Serbia). Institute of Orthopedics and Traumatology / Lesic, A., Clinical Center of Serbia, Belgrade (Serbia). Institute of Orthopedics and Traumatology / Cupic, V., University of Belgrade, Belgrade (Serbia). Faculty of Veterinary Medicine / Milosevic, I., Clinical Center of Serbia, Belgrade (Serbia). Institute of Orthopedics and Traumatology / Kanjuh, V., Serbian Academy of Sciences and Arts, Belgrade (Serbia)

Acta Veterinaria (Serbia)

(2010) Volume v. 60, Issue (2-3), Page(s) p. 145–154

Abstract: Pinacidil, a previously studied potassium channel opener (PCO), is a potent antihypertensive agent in animals and humans. Its mechanism of action is not completly defined. The aim of our study was to investigate the antivasoconstricting effect of ... ...

Abstract	Pinacidil, a previously studied potassium channel opener (PCO), is a potent antihypertensive agent in animals and humans. Its mechanism of action is not completly defined. The aim of our study was to investigate the antivasoconstricting effect of pinacidil on the isolated RA and to study whether this effect is endothelium-dependent. Contractions of isolated RA rings intact endothelium were provoked by electrical field stimulation (EFS, 20Hz) or exogenously applied noradrenaline (NA, 10 microM). Pinacidil (10 nM-0.1 mM) produced a concentration-dependent inhibition of both EFS- and NA-evoked contractions (P is greater than 0.05). NO synthesis inhibitor, L-NAME (10 microM) and the guanylate cyclase inhibitor, methylene blue (10 microM) did partly antagonize NA-evoked contractions and were without effect on EFS-induced contractions. Thus, the antivasoconstrictor effect of pinacidil on RA is partly endothelium-dependent and probably mediated via cGMP-dependent NO-pathway.
Keywords	ANIMALS ; MANKIND ; ARTERIES ; CARDIOVASCULAR DISEASES ; CARDIOVASCULAR AGENTS ; ANIMAL ; GENRE HUMAIN ; ARTERE ; MALADIE CARDIOVASCULAIRE ; MODIFICATEUR CARDIOVASCULAIRE ; ANIMALES ; GENERO HUMANO ; ARTERIAS ; ENFERMEDADES CARDIOVASCULARES ; MEDICAMENTOS CARDIOVASCULARES ; http://www.fao.org/aos/agrovoc#c_444 ; http://www.fao.org/aos/agrovoc#c_4586 ; http://www.fao.org/aos/agrovoc#c_8948 ; http://www.fao.org/aos/agrovoc#c_34231 ; http://www.fao.org/aos/agrovoc#c_1316
Language	English
Document type	Article
ISSN	0567-8315
Database	AGRIS - International Information System for the Agricultural Sciences and Technology

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Article: Role of hepatic stellate cell (HSCs) in the development of hepatic fibrosis in cats with polycystic kidney disease (PKD)

Aleksić-Kovacević, S., Faculty of Veterinary Medicine, Belgrade (Serbia) / Kukolj, V., Faculty of Veterinary Medicine, Belgrade (Serbia) / Kureljušić, B., Institute of Veterinary Medicine of Serbia, Belgrade (Serbia) / Marinković, D., Faculty of Veterinary Medicine, Belgrade (Serbia) / Knežević, Đ., Clinical Center of Serbia, Belgrade (Serbia). Institute of Digestive Diseases / Ignjatović, I., Clinical Center of Serbia, Belgrade (Serbia). Institute of Digestive Diseases / Jovanović, M., Faculty of Veterinary Medicine, Belgrade (Serbia) / Knežević, M., Faculty of Veterinary Medicine, Belgrade (Serbia) / Gledić, D., Faculty of Veterinary Medicine, Belgrade (Serbia)

Acta Veterinaria (Serbia)

(2010) Volume v. 60, Issue (4), Page(s) p. 391–400

Abstract: Hepatic stellate cells (HSCs) play a significant role in hepatic fibrogenesis. In the following study we described the distribution of cells that express alpha-smooth muscle actin (alfa-SMA) and desmin in the cat liver with various degrees of fibrosis, ... ...

Abstract	Hepatic stellate cells (HSCs) play a significant role in hepatic fibrogenesis. In the following study we described the distribution of cells that express alpha-smooth muscle actin (alfa-SMA) and desmin in the cat liver with various degrees of fibrosis, as well as the significance of hepatic stellate cells and portal myofibroblasts in the genesis of fibrosis in cats with polycystic kideny disease. Liver samples from 15 necropsied Persian cats were examined. Liver fibrosis was confirmed in cats with terminal stage of chronic cholangiohepatitis and it was characterized by connective tissue septa which divide the liver parenchyma into irregular lobuli. Inflammation in the cat liver is connected with the activation of periductal myofibroblasts. The intensity of immunopositivity of perisinusoidal HSCs to alfa-SMA and desmin varied depending on the degree of fibrosis and was the strongest in livers of cats with cirrhosis.
Keywords	CATS ; LIVER ; LIVER DISEASES ; HISTOPATHOLOGY ; BIOCHEMISTRY ; IMMUNOLOGY ; CHAT ; FOIE ; MALADIE DU FOIE ; HISTOPATHOLOGIE ; BIOCHIMIE ; IMMUNOLOGIE ; GATO ; HIGADO ; ENFERMEDADES HEPATICAS ; HISTOPATOLOGIA ; BIOQUIMICA ; INMUNOLOGIA ; http://www.fao.org/aos/agrovoc#c_1390 ; http://www.fao.org/aos/agrovoc#c_4395 ; http://www.fao.org/aos/agrovoc#c_4396 ; http://www.fao.org/aos/agrovoc#c_34016 ; http://www.fao.org/aos/agrovoc#c_910 ; http://www.fao.org/aos/agrovoc#c_3808
Language	English
Document type	Article
ISSN	0567-8315
Database	AGRIS - International Information System for the Agricultural Sciences and Technology

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Article: Neurotoxicity evaluation of fentanyl analogs in rats

Vučković, S., Faculty of Medicine, Belgrade (Serbia) / Savić-Vujović K., Faculty of Medicine, Belgrade (Serbia) / Ivanović, M., Faculty of Chemistry, Belgrade (Serbia) / Došen-Mićović, Lj., Faculty of Chemistry, Belgrade (Serbia) / Todorović, Z., Faculty of Medicine, Belgrade (Serbia) / Vučetić, Č., Clinical Center of Serbia, Belgrade (Serbia). Institute for Orthopaedic Surgery and Traumatology / Prostran, M., Faculty of Medicine, Belgrade (Serbia)

Acta Veterinaria (Serbia)

(2012) Volume v. 62, Issue (1), Page(s) p. 3–15

Abstract: This study aimed at evaluating the neurotoxicity of fentanyl analogs: (+/-)-cis-3-carbomethoxy fentanyl (C) and (+/-)-trans-3- carbomethoxy fentanyl (T) in rats. C and T are less potent (2.4-3.1 and 8.4-12.3 times, respectively) than fentanyl (F) in ... ...

Abstract	This study aimed at evaluating the neurotoxicity of fentanyl analogs: (+/-)-cis-3-carbomethoxy fentanyl (C) and (+/-)-trans-3- carbomethoxy fentanyl (T) in rats. C and T are less potent (2.4-3.1 and 8.4-12.3 times, respectively) than fentanyl (F) in producing both antinociception and morphine-like neurotoxic effects: loss of pinna reflex, Straub tail, impairment of motor coordination, catalepsy, loss of corneal reflex and loss of righting reflex. All of the effects tested were dose-dependent and they were abolished by pretreatment with naloxone, nonselective antagonist of opioid receptors, indicating that they are mediated via opioid receptors. Further, F, C and T exhibited similar relative potencies in producing all tested effects, indicating that similar receptors are involved in producing antinociceptive and neurotoxic effects, most probably of mu type. By using equiantinociceptive doses, C and T produced significantly shorter duration of both antinociception and neurotoxicity than F. No significant differences between therapeutic indices for F, C and T were found, indicating that these compounds are equally safe and tolerable in respect to the neurotoxic effects tested. Neurotoxicity testing presented in this paper may be useful in studying the structure-activity relationship of opioid congeners.
Keywords	RATS ; NEUROTOXINS ; NEUROTOXICITY ; RAT ; NEUROTOXINE ; NEUROTOXICITA ; RATA ; NEUROTOXINAS ; NEUROTOXICIDAD ; http://www.fao.org/aos/agrovoc#c_6464 ; http://www.fao.org/aos/agrovoc#c_24556 ; http://www.fao.org/aos/agrovoc#c_34316
Language	English
Document type	Article
ISSN	0567-8315
Database	AGRIS - International Information System for the Agricultural Sciences and Technology

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Article: Apoptotic clearance in rabbits with experimental pulmonary emphysema

Žunić-Božinovski, S., University of Belgrade (Serbia). School of Medicine, Institute of Pathophysiology / Žunić, S., PET National Center, Belgrade (Serbia). Clinical Center of Serbia / Mladenović-Đorđević, A., Institute for Biological Research Siniša Stanković, Belgrade (Serbia) / Ruždijić, S., Institute for Biological Research Siniša Stanković, Belgrade (Serbia) / Kanazir, S., Institute for Biological Research Siniša Stanković, Belgrade (Serbia)

Acta Veterinaria (Serbia)

(2011) Volume v. 61, Issue (5-6), Page(s) p. 513–522

Abstract: In order to better understand pathogenesis of pulmonary emphysema, the model of experimentally induced pulmonary emphysema in Chinchilla rabbits was used for the estimation of apoptotic clearance of pulmonary tissue. Bronchoalveolar lavage was performed ... ...

Abstract	In order to better understand pathogenesis of pulmonary emphysema, the model of experimentally induced pulmonary emphysema in Chinchilla rabbits was used for the estimation of apoptotic clearance of pulmonary tissue. Bronchoalveolar lavage was performed in three groups of animals: experimental group-E on hypercholesterolemic diet (4% edible oil solution of crystalline cholesterol), control group-C1 on standard diet for that animal species and animals on oily diet-C2. Apoptotic detection in cytocentrifuge preparations of lung washings was evaluated by in situ TUNEL. The property of alveolar macrophages to engulf apoptotic cells was estimated by light microscopy including 300 features (related subsequent steps: adsorption, internalization and intracellular processing of free apoptotic bodies) and was evaluated by scoring and indexing method. Internalization of apoptotic bodies by alveolar macrophages, as well as free apoptotic bodies were decreased in E compared to both C1 and C2 group (p is less than 0.01 and p is less than 0.05 respectively). Intracellular processing of apoptotic bodies by alveolar macrophages is significantly decreased in C2 in comparison with E (p is less than 0.05) and C1 group (p is less than 0.01). Apoptotic capacity of pulmonary tissue is significantly decreased in C2 in comparison with C1 group (p is less than 0.01). The results implicate that immuno-metabolic competence of pulmonary tissue might be essentially associated with tissue remodeling in pulmonary emphysema.
Keywords	RABBITS ; PULMONARY EMPHYSEMA ; APOPTOSIS ; MACROPHAGES ; LAPIN (ORYCTOLAGUS) ; EMPHYSAME PULMONAIRE ; APOPTOSE ; MACROPHAGE ; CONEJO (ORYCTOLAGUS) ; ENFISEMA PULMONAR ; APOPTOSIS ; MACROFAGOS ; http://www.fao.org/aos/agrovoc#c_6414 ; http://www.fao.org/aos/agrovoc#c_16806 ; http://www.fao.org/aos/agrovoc#c_36634 ; http://www.fao.org/aos/agrovoc#c_12316
Language	English
Document type	Article
ISSN	0567-8315
Database	AGRIS - International Information System for the Agricultural Sciences and Technology

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Article: First isolation of methicillin-resistant Staphylococcus aureus from pigs' clinical samples in Serbia

Zutic, M., Institute of Veterinary Medicine of Serbia, Belgrade (Serbia). Dept. of Microbiology / Cirkovic, I., University of Belgrade (Serbia). Inst. of Microbiology and Immunology / Pavlovic, L., Institute of Public Health of Serbia, Belgrade (Serbia). Center for Microbiology / Asanin, J., University of Belgrade (Serbia). Faculty of Technology and Metallurgy / Jovanovic, S., Clinical Center of Serbia, Belgrade (Serbia). Dept. of Microbiology / Zutic, J., Medicine of Serbia, Belgrade (Serbia). Dept. of Microbiology / Asanin, R., University of Belgrade (Serbia). Faculty of Veterinary Medicine

Acta Veterinaria (Czech Republic)

(Sep 2012) Volume v. 81, Issue (3), Page(s) p. 225–227

Abstract: Methicillin-resistant Staphylococcus aureus was isolated from a sow with endometritis and her five piglets with dermatitis originating from a Serbian farm. Identification of the strains was done by automated system and confirmed by polymerase chain ... ...

Abstract	Methicillin-resistant Staphylococcus aureus was isolated from a sow with endometritis and her five piglets with dermatitis originating from a Serbian farm. Identification of the strains was done by automated system and confirmed by polymerase chain reaction for mecA and nuc genes. Detection of Staphylococcal Cassette Chromosome mec type was performed by multiplex polymerase chain reaction. Antimicrobial susceptibility testing on erythromycin, clindamycin, gentamicin, kanamycin, tobramycin, ciprofloxacin, tetracycline, trimethoprim/sulfamethoxazole and vancomycin was done by disc diffusion method. Six isolated strains from the infected sow and her piglets showed resistance only to tetracycline beside resistance to all beta-lactam antibiotics. In the tested methicillin-resistant Staphylococcus aureus isolates, Staphylococcal Cassette Chromosome mec type V was present. To our knowledge, this finding is the first documented detection of methicillin-resistant Staphylococcus aureus from pigs' clinical samples in Serbia. The results of our study indicate the emergence of methicillin-resistant Staphylococcus aureus in a pig farm in Serbia highlighting the threat of this antibiotic-resistant microorganism as a pathogen causing both animal and human infections.
Keywords	SOWS ; PIGLETS ; SWINE ; STAPHYLOCOCCUS AUREUS ; PATHOGENS ; PATHOTYPES ; ENDOMETRITIS ; DERMATITIS ; INFECTIOUS DISEASES ; ZOONOSES ; ISOLATION ; ERYTHROMYCIN ; GENTAMYCIN ; KANAMYCIN ; TETRACYCLINES ; ANTIBIOTICS ; BACTERICIDES ; ANTIMICROBIALS ; DRUG RESISTANCE ; RESISTANCE TO CHEMICALS ; MICROBIAL PROPERTIES ; CHROMOSOMES ; GENES ; PCR ; TESTING ; METHODS ; SERBIA AND MONTENEGRO ; TRUIE ; PORCELET ; PORCIN ; STAPHYLOCOCCUS AUREUS ; AGENT PATHOGENE ; PATHOTYPE ; ENDOMETRITE ; DERMATITE ; MALADIE INFECTIEUSE ; ZOONOSE ; ISOLEMENT ; ERYTHROMYCINE ; GENTAMYCINE ; KANAMYCINE ; TETRACYCLINE ; ANTIBIOTIQUE ; BACTERICIDE ; ANTIMICROBIEN ; RESISTANCE AUX MEDICAMENTS ; RESISTANCE AUX PRODUITS CHIMIQUES ; PROPRIETE DES MICRO-ORGANISMES ; CHROMOSOME ; GENE ; PCR ; TESTAGE ; METHODE ; SERBIE-MONTENEGRO ; CERDAS ; LECHON ; CERDO ; STAPHYLOCOCCUS AUREAS ; ORGANISMOS PATOGENOS ; PATOTIPOS ; ENDOMETRITIS ; DERMATITIS ; ENFERMEDADES INFECCIOSAS ; ZOONOSIS ; AISLAMIENTO ; ERITROMICINA ; GENTAMICINA ; KANAMICINA ; TETRACICLINA ; ANTIBIOTICOS ; BACTERICIDAS ; ANTIMICROBIANOS ; RESISTENCIA A MEDICAMENTOS ; RESISTENCIA A PRODUCTOS QUIMICOS ; PODER MICROBIANO ; CROMOSOMAS ; GENES ; PCR ; ENSAYO ; METODOS ; SERBIA Y MONTENEGRO ; http://www.fao.org/aos/agrovoc#c_7271 ; http://www.fao.org/aos/agrovoc#c_5872 ; http://www.fao.org/aos/agrovoc#c_7555 ; http://www.fao.org/aos/agrovoc#c_16429 ; http://www.fao.org/aos/agrovoc#c_5630 ; http://www.fao.org/aos/agrovoc#c_24059 ; http://www.fao.org/aos/agrovoc#c_10600 ; http://www.fao.org/aos/agrovoc#c_10341 ; http://www.fao.org/aos/agrovoc#c_34024 ; http://www.fao.org/aos/agrovoc#c_8530 ; http://www.fao.org/aos/agrovoc#c_37744 ; http://www.fao.org/aos/agrovoc#c_10665 ; http://www.fao.org/aos/agrovoc#c_11123 ; http://www.fao.org/aos/agrovoc#c_11937 ; http://www.fao.org/aos/agrovoc#c_7687 ; http://www.fao.org/aos/agrovoc#c_492 ; http://www.fao.org/aos/agrovoc#c_9048 ; http://www.fao.org/aos/agrovoc#c_509 ; http://www.fao.org/aos/agrovoc#c_10471 ; http://www.fao.org/aos/agrovoc#c_5736 ; http://www.fao.org/aos/agrovoc#c_4798 ; http://www.fao.org/aos/agrovoc#c_1598 ; http://www.fao.org/aos/agrovoc#c_3214 ; http://www.fao.org/aos/agrovoc#c_34079 ; http://www.fao.org/aos/agrovoc#c_7683 ; http://www.fao.org/aos/agrovoc#c_4788 ; http://www.fao.org/aos/agrovoc#c_37896
Language	English
Document type	Article
ISSN	0001-7213
Database	AGRIS - International Information System for the Agricultural Sciences and Technology

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Article: Lyme neuroborreliosis

Milovanović, A., Shool of Medicine, Belgrade, Serbia / Milovanović, J., Shool of Medicine, Belgrade, Serbia / Obrenović, S., Faculty of Veterinary Medicine, Belgrade (Serbia) / Milovanović, A., Clinical Center of Serbia, Belgrade (Serbia) / Simonović, P., Ministry of Health, Belgrade (Serbia) / Čemerikić, D., Shool of Medicine, Belgrade, Serbia / Tačević, Z., Shool of Medicine, Belgrade, Serbia / Petronić, I., Shool of Medicine, Belgrade, Serbia / Grajić, M., Shool of Medicine, Belgrade, Serbia / Kekuš, D., High Medical Shool, Zemun (Serbia) / Popević, M., Shool of Medicine, Belgrade, Serbia

Acta Veterinaria (Serbia)

(2011) Volume v. 61, Issue (1), Page(s) p. 89–98

Abstract: Lyme borreliosis (LB) is a multisystemic zoonotic disease which in humans can involve the skin, joints, heart and/or nervous system. In this study a total of 11 patients with clinical manifestations have been assessed at the Institute for Occupational ... ...

Abstract	Lyme borreliosis (LB) is a multisystemic zoonotic disease which in humans can involve the skin, joints, heart and/or nervous system. In this study a total of 11 patients with clinical manifestations have been assessed at the Institute for Occupational Health. Evaluation of the patients was done in order to determine their working capability and further professional orientation. Patients were of different gender, age, education and profession. They fulfilled at least two of the three criteria: tick infestation data (epidemiological criteria), central and/or peripheral neurological symptoms (clinical criteria) and a positive serological finding. Diagnosis was done upon classical clinical criteria: electromyeloneurography (EMNG) analysis, neurological impairments, electroencephalography (EEG), computer tomography (CT) and/or magnetic resonance imaging (MRI). IgM and IgG antibodies against B. burgdorferi were determined by commercial ELISA kits. IgM antibodies were recorded in the serum of 4 (44.4%) and IgG in 6 (66.7%) patients. Electro-myeloneurography findings of the upper and lower limbs were positive in 5 (83.3%), electroencephalography in 4 (66.6%) of the 6 observed patients and CT was positive in 4 (36.4%) of the 5 observed patients. The study has established that in patients with neuroborreliosis (NB) the capability to carry out intellectual tasks, as well as responsible duties is impaired due to poor memory. Patients suffering from peripheral neuropathies are not fit to withstand longterm walks, weight lifting and carrying or any other form of physical stress.
Keywords	SERBIA ; MANKIND ; BORRELIOSIS ; BORRELIA BURGDORFERI ; OCCUPATIONAL HAZARDS ; SERBIE ; GENRE HUMAIN ; BORRALIOSE ; BORRELIA BURGDORFERI ; RISQUE PROFESSIONNEL ; SERBIA ; GANERO HUMANO ; BORRELIOSIS ; BORRELIA BURGDORFERI ; RIESGOS OCUPACIONALES ; http://www.fao.org/aos/agrovoc#c_49909 ; http://www.fao.org/aos/agrovoc#c_4586 ; http://www.fao.org/aos/agrovoc#c_34047 ; http://www.fao.org/aos/agrovoc#c_33630 ; http://www.fao.org/aos/agrovoc#c_24057
Language	English
Document type	Article
ISSN	0567-8315
Database	AGRIS - International Information System for the Agricultural Sciences and Technology

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