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  1. Article: Ammonia emissions to the atmosphere from leaves of wild plants and Hordeum vulgare treated with methionine sulphoximine

    Pearson, J / Clough, E.C.M / Woodall, J / Havill, D.C / Zhang, X.H

    New phytologist. Jan 1998. v. 138 (1)

    1998  

    Keywords Mercurialis perennis ; Rubus plicatus ; Primulaceae ; Hordeum vulgare ; ammonia ; gases ; leaves ; glutamate-ammonia ligase ; cell walls ; enzyme inhibitors ; pH ; stomata ; stems ; roots ; amino acid metabolism ; enzyme activity ; emissions ; chemical constituents of plants ; ammonium compounds ; species differences ; England ; Scotland
    Language English
    Dates of publication 1998-01
    Size p. 37-48.
    Document type Article
    ZDB-ID 208885-x
    ISSN 1469-8137 ; 0028-646X
    ISSN (online) 1469-8137
    ISSN 0028-646X
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection

    Nepogodiev D. / Bhangu A. / Glasbey J.C. / Li E. / Omar O.M. / Simoes J.F. / Abbott T.E. / Alser O. / Arnaud A.P. / Bankhead-Kendall B.K. / Breen K.A. / Cunha M.F. / Davidson G.H. / Di Saverio S. / Gallo G. / Griffiths E.A. / Gujjuri R.R. / Hutchinson P.J. / Kaafarani H.M. /
    Lederhuber H. / Loffler M.W. / Mashbari H.N. / Minaya-Bravo A. / Morton D.G. / Moszkowicz D. / Pata F. / Tsoulfas G. / Venn M.L. / Cox D. / Roslani A.C. / Alakaloko F. / de Vries J.-P.P. / Aaraj M.A. / Abbott S.J. / Abdalla M.O. / Abdelaal A.S. / Ademuyiwa A.O. / Aherne T.M. / Ali O.M. / Alkadeeki G.Z. / Almeida A.C. / Alrahawy M.M. / Ambler G.K. / Alameer E. / Andreani S.M. / De Andres-Asenjo B. / Antonanzas L.L. / Aoun S.G. / Ashoush F.M. / Augestad K.M. / Avellana R.B. / Ayeni F.A. / Ayorinde J.O. / Babu B.H. / Baig M.M. / Bajomo O.M. / Baker O.J. / Baker M.P. / Baldwin A.J. / Ban V.S. / Baron R.D. / Barranquero A.G. / Barry C.P. / DI Bartolomeo A. / Bass G.A. / Bath M.F. / Batjer H.H. / Beamish A.J. / Belgaumkar A.P. / Bence M.N. / Benson R.A. / Bernal-Sprekelsen J.C. / Bhama A.R. / Bhavaraju A.V. / Biffl W.L. / Blundell C.M. / Boddy A.P. / Borgstein A.B. / Bosanquet D.C. / Bosch K.D. / Bouhuwaish A.E. / Bozkurt M.A. / Brathwaite C.E. / Brown B.C. / Brown O.D. / Brown A.K. / Buarque I.L. / Bueno-Canones A.D. / Bulugma M.R. / Burke J.R. / Byrne M.H. / Cagigal-Ortega E.P. / Callcut R.A. / DI Candido F. / Canova M.E. / Carlos W.J. / Caruana E.J. / Cato L.D. / Catton A.B. / Ceretti A.P. / Chase T.J. / Chiara F.D. / Chowdhury A.H. / Chung E.A. / Cicerchia P.M. / Clough E.C. / Coleman N.L. / Collins C.G. / Collins M.L. / Colonna E.T. / Comini L.V. / Coughlin P.A. / Cruzado L.F.-G. / Davidson B.R. / Davies R.J. / Davies E.J. / Davis N.F. / Dawson B.E. / Dean B.J. / Delgado M.G.-C. / Diaz J.J. / Dickson K.E. / Diez-Alonso M.M. / Dixon J.R. / Doe M.J. / Drake T.D. / Drake F.T. / Duffy J.P. / Dunne D.F. / Dunne N.J. / Duran-Munoz-Cruzado V.M. / Durst A.Z. / Eardley N.J. / Edwards J.G. / Elfallal A.H. / Elfiky M.M. / Elliott J.A. / Emile S.H. / Emslie K.M. / Endorf F.W. / Engel J.L. / Enjuto D.T. / Etchill E.W. / Evans J.P. / Fahey B.A. / Faria C.S. / Feo C.V. / Ferguson H.J. / Fernandez B.D. / Fernandez A.G. / Fernandez A.J. / Fernandez-Pacheco B.C. / Fitzgerald J.E. / Fonsi G.B. / Font R.F. / Fowler A.L. / Fretwell K.R. / Fructuoso L.S. / Fusai G.K. / Garcia M.H. / Garcia-Urena M.A. / Gill C.K. / Gisbertz S.S. / Del Giudice R. / Giuffrida M.C. / Di Giuseppe M. / Gomez M.F. / Guariglia C.A. / Hainsworth A.J. / Hall B.J. / Hall J.R. / Hammond J.S. / Haqqani M.H. / Harrison E.M. / Hazelton J.P. / van Heinsbergen M. / Hill A.D. / Hing C.B. / Hirji S.A. / Ho M.W. / Holbrook C.M. / Holme T.J. / Hopkins J.C. / Hopkinson D.N. / Hossain F.S. / Hudson V.E. / Hughes J.L. / Hwang E.S. / Ibrahim M.A. / Isolani S.M. / Jenkinson M.D. / Jenny H.E. / Jeyaretna D.S. / Jones R.P. / Jones A.P. / Jonker P.K. / Jonsson M.L. / Joyce D.P. / Kalkwarf K.J. / Kamarajah S.K. / El Kassas M. / Kavanagh D.O. / Keatley J.M. / Khalefa M.A. / Khan J.S. / Kirmani B.H. / Kisiel A.P. / Kouris S.M. / Kowal M.R. / Labib P.L. / Larkin J.O. / Lauscher J.C. / Leclercq W.K. / Ledesma F.S. / Leite-Moreira A.M. / Leung E.Y. / Lewis S.E. / Lima M.J. / Lin D.J. / Liu H.H. / Lowery A.J. / Lozano S.M. / Luney C.R. / Maia M.M. / Mariani N.M. / Marino M.V. / Marra A.A. / Marsh C.L. / Martin R.C. / McCluney S.J. / McIntyre R.C. / Mckay S.C. / McKevitt K.L. / Meagher A.D. / Mehdi M.Q. / Mehigan B.J. / Gonzalez-De Miguel M. / De Miguel-Ardevines M.-C. / Mills S.J. / Mohan H.M. / Moir J.A. / Monson J.R. / Monteiro J.M. / Montella M.T. / Montesinos C.S. / Morgom M.M. / Moura F.S. / Muguerza J.M. / Murphy S.H. / De Nardi P. / Naumann D.N. / Neary P.C. / Neely D.T. / Ng-Kamstra J.S. / Ngu A.W. / Nguyen T.A. / Nita G.E. / Nunes Q.M. / Nygaard R.M. / O'Meara L.B. / O'Neill J.R. / Okafor B.U. / Olson S.A. / Oo A.Y. / Ormazabal P.C. / Osorio A.L. / Pachl M.J. / Parry J.T. / Patel P.K. / Perez-Sanchez L.E. / Pevidal A.N. / Pezzuto A.P. / Philp M.M. / Pinkney T.D. / Pollok J.M. / Povey M.G. / Poza A.A. / Rajgor A.D. / Rao J.N. / Raptis D.A. / Rice H.E. / Ridgway P.F. / Rivas A.M. / Rodriguez-Sanjuan J.C. / Rogers L.J. / Da Roit A. / Rollett R.A. / Romera J.L. / Rooney S.M. / Roxo V.I. / Le Roy B. / Rubio E.E. / Ruiz C.C. / Ruiz M.L. / Ryan E.J. / Saad A.R. / Saeed S.A. / Salama H.A. / Salamah A.A. / Sampietro G.M. / Sarma D.R. / Schaffer K.B. / Schnitzbauer A.A. / Scurrah R.J. / Serevina O.L. / Serralheiro P.A. / Sewards J.M. / Shackcloth M.J. / Shaw A.V. / Sheel A.R. / Sica G.S. / De Simone V. / Singh A.A. / Singh R.P. / Skelly B.L. / Smith H.G. / Sohail A.H. / Spalding D.R. / Springford L.R. / Ssentongo A.E. / Steinkamp P.J. / Stevens K.A. / Stewart G.D. / Stylianides N.A. / Sullivan T.B. / Taher A.S. / Tamimy M.S. / Tang A.M. / Tebala G.D. / Tejero-Pintor F.J. / Thaha M.A. / Thomas A.J. / De Toma G. / La Torre F. / Torres A.J. / Townshend D.N. / Trout I.M. / Tucker S.C. / Ubhi H.K. / Vega V.A. / Velmahos G.C. / Velopulos C.G. / Viswanath Y.K. / Vivas A.A. / Wade R.G. / Wadley M.S. / Wall J.J. / Walters A.M. / Warren O.J. / Weerasinghe C.K. / Wilkin R.J. / Williams K.J. / Winter S.C. / Wormald J.C. / Wright F.L. / Xyda S.E. / Young A.L. / Youssef M.M. / Yousuf F.B. / El Youzouri H. / Zappa M.A. / Abate E. / Abdalaziz H. / Abdelkarim M. / Abdou H. / Aboelkassem-Ibrahim A. / Abuown A. / Acebes-Garcia F. / Acharya M. / Adamina M. / Addae-Boateng E. / Aftab R. / Agarwal A. / Aguilar J. / Ahmed Y. / Aitken E. / Al-Azzawi M. / Al-Embideen S. / Al-Masri M. / Al-Najjar H. / Al-Sukaini A. / Alam R. / Alderson D. / Aliyeva Z. / Aljanadi F. / Almasri M. / Alonso-Ortuno P. / Altintoprak F. / Amira G. / Amjad R. / Anania G. / Andabaka T. / Angelou D. / Annamalai S. / Annessi V. / Anthoney J. / Anwar S. / Anwer M. / Aragon-Chamizo J. / Ardito A. / Arigoni M. / Armao T. / Arminio A. / Armstrong L. / Arnaud A. / Asaad P. / Ashcroft J. / Ashmore C. / Asqalan A. / Asti E. / Aubry E. / Aytac E. / Ayuso-Herrera E. / Baeza M. / Bailon-Cuadrado M. / Bakmaz B. / Baldi C. / Baldini E. / Baldo S. / Ballabio M. / Baloyiannis I. / Baltazar G. / Bambina F. / Bandiera A. / Barlow E. / Barmasse R. / Barmpagianni C. / Baronio G. / Barra F. / Bartsch A.-M. / Basgaran A. / Basha A. / Bashkirova V. / Bastazza M. / Baumber R. / Belcher E. / Belvedere A. / Benitez-Linero I. / Bergeat D. / Bernasconi M. / Bhalla A. / Bhutiani N. / Bianco F. / Bisagni P. / Blake I. / Blanco-Colino R. / Blazquez-Martin A. / Boal M. / Bonavina L. / Bonavina G. / Bond-Smith G. / Booth K. / Borges F. / Borghi F. / Bouchagier K. / Bourke G. / Boyle E. / Brachini G. / Brain J. / Brar A. / Breckles L. / Bretagnol F. / Brixton G. / Bruzzaniti P. / Bueser T. / Burnside N. / Caballero A. / Calcerrada-Alises E. / Callahan M. / Camarero E. / Campagnaro T. / Campanelli M. / Candiani M. / Cantalejo-Diaz M. / Cao H. / Capelli P. / Capizzi V. / Carcano G. / Carissimi F. / Carlini M. / Carlucci M. / Carmichael H. / Carrasco M. / Carrillo M. / Carvello M. / Casati M. / Castoro C. / Catalan V. / Cavaleiro S. / Cellerino P. / Centinaio G. / Cernei C. / Cerro C. / Cervellera M. / Chakrabortee S. / Chamberlain S. / Chan J. / Chang G. / Chaudhry D. / Chebaro A. / Chen D. / Chetty G. / Chia Z. / Chiappini A. / Chiarugi M. / Chidambaram S. / Chiozza M. / Cholewa H. / Chong C. / Choolani-Bhojwani E. / Christoforidis D. / Chui K. / Chung C. / Cirillo B. / Citterio D. / Clermidi P. / Coccolini F. / Colletti G. / Compagnoni B. / Concepcion-Martin V. / Confalonieri M. / Connolly H. / Conso C. / Conti L. / Cooper Z. / Cordera F. / Corral J. / Costa M. / Costanzi A. / Cotsoglou C. / Cozza V. / Cuming T. / Curtis M. / Cuschieri J. / D'Agruma M. / D'Andrea G. / Daliya P. / Dare O. / Darko E. / Day A. / Dehal A. / Dehart D. / Delgado-Oliver E. / Denning M. / Desai A. / Desender L. / Dester S. / Diaz-Garcia A. / Diaz-Pena P. / Dousset B. / Doussot A. / Duchateau N. / Duff S. / Dunning J. / Duque-Mallen V. / Dziakova J. / Egan B. / Egan R. / El-Ali A. / Elfeki H. / Elhadi M. / Eljareh M. / Elkady R. / Elkhafeefi F. / Elmore U. / Elmoslemany T. / Emmerson O. / Enemosah I. / English C. / English W. / Escartin J. / Estaire-Gomez M. / Evans L. / Evans J. / Exley R. / Fabbri N. / Falco G. / Familiari P. / Fancellu A. / Farik S. / Farrell T. / Fehervari M. / Fell A. / Fernandez-Camunas A. / Fernandez-Marin R. / Fernandez-Martinez M. / Ferrara F. / Ferrari G. / Ferrero S. / Findlay L. / Fiore M. / Fiori E. / Flatman M. / Flindall I. / Flor B. / Fontana T. / Ford S. / Ford D. / Forlani S. / Francone E. / Frattaruolo C. / Frio F. / Gagliano A. / Gagliardi F. / Gahunia S. / Gaino F. / Gala T. / Galfrascoli E. / Galimberti L. / Gallagher P. / Galleano R. / Galvan-Perez A. / Gammeri E. / Ganau M. / Garces-Garcia R. / Garulli G. / Gascon-Ferrer I. / Gattolin A. / Gaujoux S. / Gentilli S. / Georgiades F. / Ghanbari A. / Ghosh D. / Giacometti M. / Giblin A.-V. / Gilbert C. / Gimenez C. / Giorgakis E. / Gipponi M. / Glen P. / Goatly G. / Gobatti D. / Godbole C. / Gohil K. / Gomez M. / Gomez-Rosado J.-C. / Gonullu E. / Gonzalez-Gonzalez E. / Gordini L. / Gracia I. / Gracia-Roche C. / Granieri S. / Green S. / Grivon M. / Grove T. / Guaglio M. / Guaitoli E. / Guglielmi A. / Guha S. / Gustavino C. / Habeeb A. / Hagger R. / Hakmi H. / Halkias C. / Hall C. / Hampton M. / Handa S. / Hansen L. / Haq I. / Harky A. / Harries R. / Harrison J. / Hasan R. / Hawari M. / Hawkin P. / Hebblethwaite B. / Henriques S. / Heritage E. / Hernandez-Juara P. / Herrero-Lopez M. / Hervieux E. / Heyd B. / Higgs S. / Hitchman L. / Ho B. / Hogan A. / Holzle F. / Hossain T. / Hurt L. / Hutchinson P. / Iacob G. / Iannone I. / Ibrahim S. / Iovino D. / Isik A. / Jafarova S. / Jamil T. / Jayaraju U. / Jenner E. / Jimenez-Higuera E. / Jimeno J. / Jones M. / Judkins N. / Kalavrezos N. / Kalidindi V. / Kalkat M. / Kamal M. / Kamphues C. / Kang C. / Kara Y. / Karam E. / Karim A. / Kashora F. / Kearney D. / Khajuria A. / Khan U. / Khan A. / Khatri C. / Kinnaman G. / Kinross J. / Kler A. / Klimopoulos S. / Kocatas A. / Kolias A. / Konigsrainer A. / Konsten J. / Kontovounisios C. / Kourdouli A. / Krishnan E. / Kristinsson S. / Kruijff S. / Kudsk-Iversen S. / Kufeji D. / Kugler N. / Kulkarni R. / Kurihara H. / Laface L. / Lakkis Z. / Lami M. / Landaluce-Olavarria A. / Lapolla P. / Lawani I. / Lawday S. / Lazaro A. / Lecolle K. / Leventoglu S. / Li Z. / Liew I. / Lisi G. / Lizzi V. / Lo T. / Lomiento D. / Longhi M. / Lostis E. / Lostoridis E. / Loubani M. / Lowy-Benoliel A. / Lucianetti A. / Luke L. / Lunevicius R. / Luraghi M. / Lye G. / Mabrouk I. / Macchi A. / MacDonald L. / Machairas N. / Madonini M. / Magowan D. / Maisonneuve E. / Majkowska A. / Majkowski L. / Mak J. / Malabarba S. / Malerba M. / Mannan S. / Manson J. / Mansuri A. / Mantoglu B. / Manu N. / Maqsood A. / Marano A. / Marchbank A. / Marcos-Santos P. / Marrano E. / Martin J. / Martin E. / Martin G. / Martin-Albo L. / Martin-Roman L. / Martinelli F. / Martinez-dePaz F. / Martinez-German A. / Martinez-Pinedo C. / Martins R. / Marwan H. / Marzi F. / Mathieu P. / Matute-Najarro M.-S. / Maw A. / Mazingi D. / Mazzaferro V. / McCanny A. / McKenzie K. / McLarty N. / McPherson I. / Medina E. / Mediratta S. / Medone M. / Mehra G. / Mele S. / Melero-Cortes L. / Mendoza-Moreno F. / Meneghini S. / Mercante G. / Merdrignac A. / Merola S. / Metallidis S. / Michel M. / Migliore M. / Mihanovic J. / Miller D. / Mingoli A. / Minto G. / Mirabella A. / Misra N. / Mitrasinovic S. / Miu V. / Moawad N. / Mochet S. / Modabber A. / Mohammad A. / Mohan M. / Moliner-Sanchez C. / Mongelli F. / Monteleone M. / Montuori M. / Moore R. / Mora-Guzman I. / Morales X. / Morales D. / Morelli L. / Morgan R. / Morris C. / Mortini P. / Mosca A. / Motter D. / Moug S. / Mukherjee S. / Najdy M. / Nakas A. / Namazov I. / Naredla P. / Nasef E. / Nassa H. / Nath R. / Navarro-Sanchez A. / Nazarian S. / Negri G. / Nehra D. / Neil-Dwyer J. / Neri J. / Newton K. / Nikaj H. / Niquen M. / Nobile S. / Nogueiro J. / Ntirenganya F. / Nugent M. / Nunez J. / Ocana J. / Okechukwu V. / Oliva-Mompean F. / Oliveira A. / Ollat D. / Onos L. / Osagie-Clouard L. / Osman K. / Ottolina J. / Ourieff J. / Outani O. / Oyewole B. / Ozben V. / Pacheco-Sanchez D. / Padilla-Valverde D. / Pai M. / Paiella S. / Paisley S. / Palini G. / Palmeri M. / Panahi P. / Parente A. / Parlanti D. / Parmar C. / Pascual A. / Patel M. / Pathak A. / Patil S. / Pattyn P. / Peckham-Cooper A. / Pedrazzani C. / Pellino G. / Peluso C. / Pereira A. / Pereira-Neves A. / Perez-Diaz M.D. / Perez-Gonzalez M. / Perez-Saborido B. / Perivoliotis K. / Perkins C. / Peros G. / Perotto O. / Perra T. / Petrone P. / Phenix G. / Picazo S. / Picon-Rodriguez R. / Piloni M. / Pingarron-Martin L. / Pinotti E. / Pisanu A. / Pizzini P. / Pockney P. / Podda M. / Podolsky D. / Poggioli G. / Pompili C. / Pontari M. / Porcu A. / Potter R. / Price C. / Pruvot F.-R. / Pujol-Muncunill R. / Puppo A. / Quante M. / Quintana-Villamandos B. / Qureshi A. / Radenkovic D. / Rakvin I. / Ramallo-Solis I. / Ramcharan S. / Ramos D. / Ramos-Bonilla A. / Ramzi J. / Rathinam S. / Rausa E. / Ravaioli M. / Ravindran S. / Raymond T. / Razik A. / Redfern J. / Reguera-Rosal J. / Rela M. / Rey-Biel J. / Rey-Valcarcel C. / Ribolla M. / Richards T. / Richmond M. / Righini E. / Rio-Gomez J. / Riyat H. / Rizvi S. / Roberts K. / Roberts M. / Robertson S. / Robertson R. / Robin-Valle A. / Rochon M. / Rojo M. / Rolli L. / Romano S. / Ross E. / Ross H. / Rossborough C. / Rottoli M. / Ruiz-Grande F. / Ruiz-Martin I. / Ruiz-Soriano M. / Ruzzenente A. / Ryska O. / Saez C. / Sagnotta A. / Sahnan K. / Sahni A. / Salim A. / Sallam I. / Salvia R. / Samadov E. / Sammarco G. / Sampaio-Alves M. / Sanchez-Arteaga A. / Sanchez-Fuentes M.-N. / Sanchez-Pelaez D. / Sanchez-Perez C. / Sanchez-Rubio M. / Sancho-Muriel J. / Sanders J. / Santero-Ramirez M.-P. / Santora T. / Santoro A. / Santos I. / Santos-Sousa H. / Sapienza P. / Sartarelli L. / Sarveswaran J. / Sasia D. / Saudemont A. / Saudi-Moro S. / Saxena S. / Saxena D. / Sayasneh A. / Scalabre A. / Schache A. / Schiavina R. / Schineis C. / Schreckenbach T. / Scorza A. / Scott L. / Seegert S. / Seguin-Givelet A. / Senent-Boza A. / Seymour K. / Shabana A. / 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Trompeter A. / Trotta F. / Truant S. / Trujillo-Diaz J. / Turco C. / Turrado-Rodriguez V. / Turri G. / Tustin H. / Tyler J. / Tzedakis S. / Tzovaras G. / Uittenbogaart M. / Ullah R. / Urban S. / Urbani A. / Usai A. / Vaccarella G. / Valdes-Hernandez J. / Valsecchi L. / Vashisht R. / Vazquez-Fernandez A. / Venn M. / Vera-Mansilla C. / Vergari R. / Vescio G. / Vidya R. / Vieira P. / Vijay V. / Vimalachandran D. / Violante T. / Volpe A. / Vovola F. / Vulliamy P. / Wall R. / Wallwork K. / Ward A. / Warwick D. / Waseem S. / Weaver H. / Wells F. / Wen J. / West R. / Whitehall E. / Wild L. / Wilkins A. / Williams G. / Williams M. / Winnand P. / Wong K. / Worku D. / Wright N. / Yalamanchili S. / Yershov D. / Yildiz A. / Young R. / Yurttas C. / Zadegan F. / Zafar N. / Zakaria R. / Zambon M. / Zanini N. / Zarate A. / Zerbib P. / Zizzo M. / Zmora O. / Zonta S. / van Berge Henegouwen M.I. / van der Plas W.Y. / Ali I.A.M. / Bakri N.A.C. / Bauset J.C.C. / Abou Chaar M.K. / Marino Cosentino L.M. / Gomez Diaz C.J. / Garcia Galocha J.L. / de Gheldere C.A. / Ataide Gomes G.M. / Beltran de Heredia J. / Blazer III D.G. / Nugent III W.C. / Ali karar A.A. / Borja De Lacy F. / Blas Laina J.L. / Shane Lester M.J. / Liyanage A.S.D. / Al Maadany F.S. / De Marchi J.A. / Ramos-De la Medina A. / Mithany R.H.M. / Sanchez del Pueblo C. / van Ramshorst G.H. / De Salas M.M. / De Souza A.C. / Dolores Del Toro M. / Archer J.E. / Odeh A. / Erridge S. / Salem H.K. / Jones G.P. / Gardner A. / Tripathi S.S. / Gregg A. / Jeganathan R. / Siddique M.H. / Lombardi C.P. / Martin B. / Leo C.A. / Dass D. / Di Franco G. / Jiao L.R. / Mari G.M. / Capitan-Morales L.-C. / Connelly T.M. / Alanbuki A. / De Virgilio A. / Schilling C. / San Miguel Mendez C. / Kulkarni G. / Nizami K. / Walsh S. / Dean H. / Ruiz-Marin M. / Houston R. / Trompetto M. / Chrastek D. / Kouritas V. / Cannoletta M. / Rosato F. / Kaushal M.V. / Costa P.M. / Elkadi H.H. / Johnstone J.R. / Irvine E. / Alvarez M.R. / Corbellini C. / Venkatesan G.S. / Mateo-Sierra O. / Martinez-Perez C. / Serrano Gonzalez J. / Hernandez Bartolome M.A. / Diaz Perez D. / Gutierrez Samaniego M. / Galindo Jara P. / Sharma N. / Smart N.J. / Keller D.S.

    an international cohort study

    2020  

    Abstract: Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and ... ...

    Abstract Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p<0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p<0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p<0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research.
    Keywords Adult ; Aged ; Betacoronavirus ; Coronavirus Infections ; Elective Surgical Procedures ; Emergency Medical Services ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia ; Viral ; Postoperative Complications ; Respiratory Tract Diseases ; Retrospective Studies ; Surgical Procedures ; Operative ; Young Adult ; covid19
    Subject code 610 ; 616
    Language English
    Publishing country it
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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