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  1. Book ; Conference proceedings: Recurrence of the disease in the renal graft

    Cochat, Pierre

    ([Transplantation and clinical immunology ; 33] ; Symposia Fondation Mérieux)

    2001  

    Institution International Conference on Transplantation and Clinical Immunology
    Author's details 33rd International Conference on Transplantation and Clinical Immunology, CITIC 2001, 29, 30 November 2001 [Lyon]. Ed. by Pierre Cochat
    Series title [Transplantation and clinical immunology ; 33]
    Symposia Fondation Mérieux
    Transplantation and clinical immunology
    Collection Transplantation and clinical immunology
    Keywords Transplantation Immunology
    Language English
    Size XII, 129 S. : Ill., graph. Darst.
    Publisher Libbey
    Publishing place Montrouge
    Publishing country France
    Document type Book ; Conference proceedings
    HBZ-ID HT013756620
    ISBN 2-7420-0414-9 ; 978-2-7420-0414-0
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2004 A 3712 order for loan Magazin

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  2. Article ; Online: Hyperoxaluries primitives et secondaires - Les concepts bougent !

    Bacchetta, Justine / Cochat, Pierre

    Medecine sciences : M/S

    2023  Volume 39, Issue 3, Page(s) 262–264

    Title translation Revolution in the field of primary and secondary hyperoxalurias: Stay tuned!
    MeSH term(s) Humans ; Hyperoxaluria ; Mutation
    Language French
    Publishing date 2023-03-21
    Publishing country France
    Document type Journal Article
    ZDB-ID 632733-3
    ISSN 1958-5381 ; 0767-0974
    ISSN (online) 1958-5381
    ISSN 0767-0974
    DOI 10.1051/medsci/2023024
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2872: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Book ; Conference proceedings: Transplantation and changing management of organ failure

    Cochat, Pierre

    proceedings of the 32nd International Conference on Transplantation and Changing Management of Organ Failure [32nd International Conference on Transplantation and Clinical Immunology], 25-26 May, 2000, [Lyon, France]

    (Transplantation and clinical immunology ; 32)

    2000  

    Institution International Conference on Transplantation and Clinical Immunology
    Author's details ed. by Pierre Cochat
    Series title Transplantation and clinical immunology ; 32
    Collection
    Keywords Transplantation ; Organversagen
    Subject Verpflanzung ; Organtransplantation ; Organ ; Organverpflanzung
    Language English
    Size IX, 247 S. : Ill., graph. Darst.
    Publisher Kluwer Acad
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    Note Includes bibliographical references and index
    HBZ-ID HT012771069
    ISBN 0-7923-6420-1 ; 978-0-7923-6420-7
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    2000 A 2962 order for loan Magazin

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  4. Book ; Conference proceedings: Immunosuppression under trial

    Cochat, Pierre

    proceedings of the 31st Conference on Transplantation and Clinical Immunology, 3 - 4 June, 1999

    (Transplantation and clinical immunology ; 31)

    1999  

    Event/congress Conference on Transplantation and Clinical Immunology (31, 1999)
    Author's details ed. by P. Cochat
    Series title Transplantation and clinical immunology ; 31
    Collection
    Keywords Immunsuppression ; Transplantation
    Subject Immundepression ; Immunsystem ; Verpflanzung ; Organtransplantation ; Organ ; Organverpflanzung
    Language English
    Size IX, 178 S. : Ill., graph. Darst.
    Publisher Kluwer Acad
    Publishing place Dordrecht u.a.
    Publishing country Netherlands
    Document type Book ; Conference proceedings
    Note Includes bibliographical references and index
    HBZ-ID HT010830684
    ISBN 0-7923-5804-X ; 978-0-7923-5804-6
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2000 A 4160 order for loan Magazin

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  5. Article ; Online: Jean-Pierre Guignard.

    Ghuysen, Marie-Sophie / Cochat, Pierre

    Pediatric nephrology (Berlin, Germany)

    2022  Volume 37, Issue 8, Page(s) 1939–1940

    Language English
    Publishing date 2022-05-19
    Publishing country Germany
    Document type Editorial
    ZDB-ID 631932-4
    ISSN 1432-198X ; 0931-041X
    ISSN (online) 1432-198X
    ISSN 0931-041X
    DOI 10.1007/s00467-022-05593-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2196: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Book ; Conference proceedings: Primary hyperoxaluria

    Cochat, Pierre

    proceedings of the third workshop, Lyon, October 21 - 22, 1994

    (Nephrology, dialysis, transplantation ; 10, Suppl. 8)

    1995  

    Event/congress Workshop on Primary Hyperoxaluria (3, 1994, Lyon)
    Author's details [Third Workshop on Primary Hyperoxaluria]. Ed. Pierre Cochat
    Series title Nephrology, dialysis, transplantation ; 10, Suppl. 8
    Collection
    Keywords Hyperoxaluria, Primary / congresses ; Hyperoxalurie
    Subject Oxalurie
    Language English
    Size 67 S. : Ill., graph. Darst.
    Publisher Oxford Univ. Press
    Publishing place Oxford
    Publishing country Great Britain
    Document type Book ; Conference proceedings
    HBZ-ID HT006786330
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

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    Zs A 2198 -10,Suppl.8- not available for loan Zeitschriften-Lesesaal

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  7. Article ; Online: Composite event-free-survival as an endpoint in oncology drug evaluation: Review and guidance perspectives from the Haute Autorité de Santé (HAS).

    Lengliné, Etienne / Baba, Joachim / de Boissieu, Paul / Beaufils, Alexandre / Desbiolles, Alice / Diatta, Thierno / Cochat, Pierre / Chevret, Sylvie

    European journal of cancer (Oxford, England : 1990)

    2024  Volume 204, Page(s) 114047

    Abstract: Background: The use of right-censored composite endpoints, such as progression-free survival, has been questioned in haemato-oncology trials due to potential bias in estimated treatment effect. This may impact the accuracy of health technology ... ...

    Abstract Background: The use of right-censored composite endpoints, such as progression-free survival, has been questioned in haemato-oncology trials due to potential bias in estimated treatment effect. This may impact the accuracy of health technology evaluations. We hypothesized that there is heterogeneity and potential sources of bias in the reporting of composite endpoints to health technology assessment (HTA) bodies.
    Methods: We reviewed the submissions for reimbursement of oncology drugs in 2021 and 2022 that used a composite endpoint in the pivotal trial, after appraisal by the French HTA body. The retrieved information included the clinical study report, protocol, and statistical analysis plan submitted by the industry. All events of the composite endpoint and all causes of censored observations were measured. The design characteristics and treatment effect estimates were recorded.
    Findings: Seventy-six submissions were selected, including seven without a right-censored endpoint and four evaluating associations, resulting in 65 analysed records: 17 for haematological and 48 for solid tumours. Out these 65 submissions, 47 (72·3%) used a randomized controlled design, and 18 (27·7%) a non-comparative design. The most frequently used composite endpoint was progression-free survival, used in 54 (83·1%) of the submissions. Censoring was possibly informative in 51 (92·7%) cases, mostly due to the onset of new treatment (44/51, 86·3%) and/or discontinuation of follow-up (33/51, 64·7%). In contrast, 38 (58·5%) trials reported a quantification of censored observations, with only 12/51 (23·5%) quantifying the informative ones. The estimated treatment effect on the composite outcome increased with the amount of censoring, suggesting a higher benefit of the drug, but remained below that on survival with poor evidence of surrogacy (R-squared=0·23).
    Interpretation: Clinical study reports should be improved in terms of reporting censoring, while stakeholders should be aware of this potential source of bias. At a minimum, sensitivity analysis that ignores intercurrent events should be requested.
    Language English
    Publishing date 2024-04-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 82061-1
    ISSN 1879-0852 ; 0277-5379 ; 0959-8049 ; 0964-1947
    ISSN (online) 1879-0852
    ISSN 0277-5379 ; 0959-8049 ; 0964-1947
    DOI 10.1016/j.ejca.2024.114047
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 456: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Zs.MO 583: Show issues

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  8. Article ; Online: Transplantation for Primary Hyperoxaluria Type 1: Designing New Strategies in the Era of Promising Therapeutic Perspectives.

    Devresse, Arnaud / Cochat, Pierre / Godefroid, Nathalie / Kanaan, Nada

    Kidney international reports

    2020  Volume 5, Issue 12, Page(s) 2136–2145

    Abstract: Primary hyperoxaluria type 1 (PH1) is an autosomal recessive disease caused by the functional defect of alanine-glyoxylate aminotransferase that results in the overproduction of oxalate. It can be devastating especially for kidneys, leading to end-stage ... ...

    Abstract Primary hyperoxaluria type 1 (PH1) is an autosomal recessive disease caused by the functional defect of alanine-glyoxylate aminotransferase that results in the overproduction of oxalate. It can be devastating especially for kidneys, leading to end-stage renal disease (ESRD) during the first 2 to 3 decades of life in most patients. Consequently, many PH1 patients need kidney transplantation. However, because PH1 is caused by a liver enzyme deficiency, the only cure of the metabolic defect is liver transplantation. Thus, current transplant strategies to treat PH1 patients with ESRD include dual liver-kidney transplantation. However, the morbidity and mortality associated with liver transplantation make these strategies far from optimal. Fortunately, a therapeutic revolution is looming. Indeed, innovative drugs are being currently tested in clinical trials, and preliminary data show impressive efficacy to reduce the hepatic overproduction of oxalate. Hopefully, with these therapies, liver transplantation will no longer be necessary. However, some patients with progressing renal disease or those who will be diagnosed with PH1 at an advanced stage of chronic kidney disease will ultimately need kidney transplantation. Here we review the current knowledge on this subject and discuss the future of kidney transplant management in PH1 patients in the era of novel therapies.
    Language English
    Publishing date 2020-09-24
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2468-0249
    ISSN (online) 2468-0249
    DOI 10.1016/j.ekir.2020.09.022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Living well with kidney disease.

    McCarthy, Florencio / Cochat, Pierre / Alhasan, Khalid / Bonilla-Felix, Melvin

    Pediatric nephrology (Berlin, Germany)

    2021  Volume 36, Issue 5, Page(s) 1035–1036

    MeSH term(s) Humans ; Kidney Diseases/diagnosis ; Kidney Diseases/therapy ; Quality of Life
    Language English
    Publishing date 2021-03-01
    Publishing country Germany
    Document type Editorial
    ZDB-ID 631932-4
    ISSN 1432-198X ; 0931-041X
    ISSN (online) 1432-198X
    ISSN 0931-041X
    DOI 10.1007/s00467-021-05011-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2196: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
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  10. Article ; Online: IPNA-ESPN Junior Master Class-a decade of successful continuing education and training in pediatric nephrology.

    Teixeira, Ana / Topaloglu, Rezan / Cochat, Pierre / Coppo, Rosanna / Levtchenko, Elena / Haffner, Dieter / Mahan, John D / Oh, Jun

    Pediatric nephrology (Berlin, Germany)

    2023  Volume 38, Issue 10, Page(s) 3201–3205

    MeSH term(s) Child ; Humans ; Nephrology ; Education, Continuing ; Societies, Medical
    Language English
    Publishing date 2023-04-04
    Publishing country Germany
    Document type Editorial
    ZDB-ID 631932-4
    ISSN 1432-198X ; 0931-041X
    ISSN (online) 1432-198X
    ISSN 0931-041X
    DOI 10.1007/s00467-023-05940-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2196: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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