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  1. Article ; Online: Oncological monitoring after transanal total mesorectal excision (TaTME) for rectal neoplasia.

    Sanchon, L / Bardaji, M / Labro, M / Curto, J / Soto, C / Puig, A / Pastor, J C / Gómez, C / Osorio, A / Guariglia, C / Pardo, S / Vidal, C / Collera, P

    Techniques in coloproctology

    2023  Volume 27, Issue 9, Page(s) 739–746

    Abstract: Background: The surgical treatment of choice for rectal neoplasia is total mesorectal excision (TME). The transanal approach enables a better approach in male and obese patients and/or those with a narrow pelvis and in patients with small tumors. Short- ... ...

    Abstract Background: The surgical treatment of choice for rectal neoplasia is total mesorectal excision (TME). The transanal approach enables a better approach in male and obese patients and/or those with a narrow pelvis and in patients with small tumors. Short-term results are comparable with those for laparoscopy or the open approach, but the medium- and long-term oncological data are sparse. The aim of the present study was to evaluate our early experience with transanal TME (TaTME).
    Methods: This was a retrospective study conducted on patients who underwent TaTME at our center between August 2013 and April 2017 with a follow-up ≥ 3 years. Histopathology, complications, mortality, neoplastic recurrence and disease-free survival were analyzed.
    Results: One hundred patients (68 men and 32 women,, median age 66.8 years [range 29.6-91.2 years]) were included. There were 67 T3 cases (67%) with 74 N0 cases (74%), the mesorectal quality was graded optimal for 87.6% and only 2 cases of radial margin involvement were detected (2%). The median follow-up period was 47.6 months (range 11.8-78.9 months). Eighteen cases of recurrence were diagnosed, of which 3 (3%) recurred locally with an average disease-free period of 43.1 months. Overall survival was 80% and mortality due to progression of disease was 13%.
    Conclusions: TaTME is a safe surgical procedure with surgical, anatomopathological and oncological results at 3 years (medium-term) comparable with those for the laparoscopic and open approaches. Better monitoring is required with studies of the long-term functional and quality of life outcomes, i.e., at 5 or 10 years.
    MeSH term(s) Humans ; Male ; Female ; Adult ; Middle Aged ; Aged ; Aged, 80 and over ; Rectum/surgery ; Rectum/pathology ; Retrospective Studies ; Quality of Life ; Postoperative Complications/surgery ; Transanal Endoscopic Surgery/methods ; Operative Time ; Rectal Neoplasms/pathology ; Laparoscopy/methods ; Treatment Outcome
    Language English
    Publishing date 2023-01-17
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 2083309-X
    ISSN 1128-045X ; 1123-6337
    ISSN (online) 1128-045X
    ISSN 1123-6337
    DOI 10.1007/s10151-023-02755-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: CCR-CARESS score for predicting operative mortality in patients with colorectal cancer.

    Baré, M / Mora, L / Torà, N / Gil, M J / Barrio, I / Collera, P / Suárez, D / Redondo, M / Escobar, A / Fernández de Larrea, N / Quintana, J M

    The British journal of surgery

    2018  Volume 105, Issue 13, Page(s) 1853–1861

    Abstract: Background: The aim of this study was to assess factors associated with outcomes after surgery for colorectal cancer and to design and internally validate a simple score for predicting perioperative mortality.: Methods: Patients undergoing surgery ... ...

    Abstract Background: The aim of this study was to assess factors associated with outcomes after surgery for colorectal cancer and to design and internally validate a simple score for predicting perioperative mortality.
    Methods: Patients undergoing surgery for primary invasive colorectal cancer in 22 centres in Spain between June 2010 and December 2012 were included. Clinical variables up to 30 days were collected prospectively. Multiple logistic regression techniques were applied and a risk score was developed. The Hosmer-Lemeshow test was applied and the area under the receiver operating characteristic (ROC) curve (AUC, with 95 per cent c.i.) was estimated.
    Results: A total of 2749 patients with a median age of 68·5 (range 24-97) years were included; the male : female ratio was approximately 2 : 1. Stage III tumours were diagnosed in 32·6 per cent and stage IV in 9·5 per cent. Open surgery was used in 39·3 per cent, and 3·6 per cent of interventions were urgent. Complications were most commonly infectious or surgical, and 25·5 per cent of patients had a transfusion during the hospital stay. The 30-day postoperative mortality rate was 1·9 (95 per cent c.i. 1·4 to 2·4) per cent. Predictive factors independently associated with mortality were: age 80 years or above (odds ratio (OR) 2·76), chronic obstructive pulmonary disease (COPD) (OR 3·62) and palliative surgery (OR 10·46). According to the categorical risk score, a patient aged 80 years or more, with COPD, and who underwent palliative surgery would have a 23·5 per cent risk of death within 30 days of the intervention.
    Conclusion: Elderly patients with co-morbidity and palliative intention of surgery have an unacceptably high risk of death.
    MeSH term(s) Adult ; Age Factors ; Aged ; Aged, 80 and over ; Colorectal Neoplasms/complications ; Colorectal Neoplasms/mortality ; Colorectal Neoplasms/surgery ; Comorbidity ; Epidemiologic Methods ; Female ; Humans ; Male ; Middle Aged ; Palliative Care/statistics & numerical data ; Pulmonary Disease, Chronic Obstructive/complications ; Pulmonary Disease, Chronic Obstructive/mortality ; Reoperation/statistics & numerical data ; Young Adult
    Language English
    Publishing date 2018-08-13
    Publishing country England
    Document type Journal Article ; Multicenter Study ; Validation Studies
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1002/bjs.10956
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Type and Consequences of Short-Term Complications in Colon Cancer Surgery, Focusing on the Oldest Old.

    Baré, Marisa / Mora, Laura / Pera, Miguel / Collera, Pablo / Redondo, Maximino / Escobar, Antonio / Anula, Rocío / Quintana, José María

    Clinical colorectal cancer

    2019  Volume 19, Issue 1, Page(s) e18–e25

    Abstract: Background: While the proportion of colon cancer occurring in older patients is expected to increase, these patients may have more complications that may lead to serious consequences. The aim of this study was assess postoperative complications and ... ...

    Abstract Background: While the proportion of colon cancer occurring in older patients is expected to increase, these patients may have more complications that may lead to serious consequences. The aim of this study was assess postoperative complications and their short-term consequences in colon cancer surgery according to age.
    Patients and methods: Patients undergoing surgery for primary invasive colon cancer in 22 centers between June 2010 and December 2012 were included. Presurgical and surgical variables were analyzed, and in-hospital major postoperative complications and its most serious consequence (no relevant, transfusion, reintervention, admission to the intensive care unit, or death) were estimated according to age group. Chi-square tests were used to analyze the possible associations between variables and age groups.
    Results: Data from 1976 patients, mean (range) age 68 (24-97) years, 62% men, were analyzed; 52.2% were aged > 69 years and 17.7% were aged > 79 years. The complication rate was 25.3%, reaching 30.9% in those aged ≥ 80 years. Older age was associated with a higher rate of postoperative infections during the hospital stay. The most common surgical complication in patients aged > 85 years was dehiscence of the anastomosis (11.5%). About 5% of patients with major complications died in the hospital (11.1% of those aged 80-84 years and 14.3% aged > 85 years). Among patients aged > 85 years, 38.1% required transfusions.
    Conclusion: Older patients should receive appropriate functional preparation before the intervention, and when the risks of the intervention outweigh the potential benefits, a nonsurgical approach may be preferable.
    MeSH term(s) Adult ; Age Factors ; Aged ; Aged, 80 and over ; Anastomosis, Surgical/adverse effects ; Blood Transfusion/statistics & numerical data ; Colectomy/adverse effects ; Colon/pathology ; Colon/surgery ; Colonic Neoplasms/mortality ; Colonic Neoplasms/pathology ; Colonic Neoplasms/surgery ; Europe/epidemiology ; Female ; Hospital Mortality ; Humans ; Length of Stay/statistics & numerical data ; Male ; Middle Aged ; Prospective Studies ; Risk Factors ; Surgical Wound Dehiscence/epidemiology ; Surgical Wound Dehiscence/etiology ; Surgical Wound Dehiscence/therapy ; Young Adult
    Language English
    Publishing date 2019-11-26
    Publishing country United States
    Document type Journal Article ; Multicenter Study ; Observational Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 2112638-0
    ISSN 1938-0674 ; 1533-0028
    ISSN (online) 1938-0674
    ISSN 1533-0028
    DOI 10.1016/j.clcc.2019.11.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Validity of the CR-POSSUM model in surgery for colorectal cancer in Spain (CCR-CARESS study) and comparison with other models to predict operative mortality.

    Baré, Marisa / Alcantara, Manuel Jesús / Gil, Maria José / Collera, Pablo / Pont, Marina / Escobar, Antonio / Sarasqueta, Cristina / Redondo, Maximino / Briones, Eduardo / Dujovne, Paula / Quintana, Jose Maria

    BMC health services research

    2018  Volume 18, Issue 1, Page(s) 49

    Abstract: Background: To validate and recalibrate the CR- POSSUM model and compared its discriminatory capacity with other European models such as POSSUM, P-POSSUM, AFC or IRCS to predict operative mortality in surgery for colorectal cancer.: Methods: ... ...

    Abstract Background: To validate and recalibrate the CR- POSSUM model and compared its discriminatory capacity with other European models such as POSSUM, P-POSSUM, AFC or IRCS to predict operative mortality in surgery for colorectal cancer.
    Methods: Prospective multicenter cohort study from 22 hospitals in Spain. We included patients undergoing planned or urgent surgery for primary invasive colorectal cancers between June 2010 and December 2012 (N = 2749). Clinical data were gathered through medical chart review. We validated and recalibrated the predictive models using logistic regression techniques. To calculate the discriminatory power of each model, we estimated the areas under the curve - AUC (95% CI). We also assessed the calibration of the models by applying the Hosmer-Lemeshow test.
    Results: In-hospital mortality was 1.5% and 30-day mortality, 1.7%. In the validation process, the discriminatory power of the CR-POSSUM for predicting in-hospital mortality was 73.6%. However, in the recalibration process, the AUCs improved slightly: the CR-POSSUM reached 75.5% (95% CI: 67.3-83.7). The discriminatory power of the CR-POSSUM for predicting 30-day mortality was 74.2% (95% CI: 67.1-81.2) after recalibration; among the other models the POSSUM had the greatest discriminatory power, with an AUC of 77.0% (95% CI: 68.9-85.2). The Hosmer-Lemeshow test showed good fit for all the recalibrated models.
    Conclusion: The CR-POSSUM and the other models showed moderate capacity to discriminate the risk of operative mortality in our context, where the actual operative mortality is low. Nevertheless the IRCS might better predict in-hospital mortality, with fewer variables, while the CR-POSSUM could be slightly better for predicting 30-day mortality.
    Trail registration: Registered at: ClinicalTrials.gov Identifier: NCT02488161.
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; Colorectal Neoplasms/mortality ; Colorectal Neoplasms/surgery ; Female ; Hospital Mortality/trends ; Hospitals/statistics & numerical data ; Humans ; Logistic Models ; Male ; Middle Aged ; Predictive Value of Tests ; Prospective Studies ; ROC Curve ; Reproducibility of Results ; Risk Assessment ; Spain/epidemiology
    Language English
    Publishing date 2018-01-29
    Publishing country England
    Document type Comparative Study ; Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't ; Validation Studies
    ISSN 1472-6963
    ISSN (online) 1472-6963
    DOI 10.1186/s12913-018-2839-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Pseudoobstrucción intestinal por enfermedad de Steinert.

    Collera, P / Ramos, F / Culell, P / Sola, M / Ballús, L / Caballé, J

    Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva

    2002  Volume 94, Issue 4, Page(s) 231–232

    Title translation Intestinal pseudo-obstruction in Steinert's disease.
    MeSH term(s) Adult ; Emergencies ; Humans ; Intestinal Pseudo-Obstruction/diagnostic imaging ; Intestinal Pseudo-Obstruction/etiology ; Intestine, Small ; Male ; Myotonic Dystrophy/complications ; Radiography, Abdominal ; Tomography, X-Ray Computed
    Language Spanish
    Publishing date 2002-04
    Publishing country Spain
    Document type Case Reports ; Letter
    ZDB-ID 1070381-0
    ISSN 1130-0108 ; 0212-7512
    ISSN 1130-0108 ; 0212-7512
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Una nueva exploración para el diagnóstico del anismo: la ecografía endoanal dinámica.

    Navarro, A / Muñoz, E / Rodríguez, J / Collera, P / Marco, C

    Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva

    1996  Volume 88, Issue 11, Page(s) 814–815

    Title translation A new test for the diagnosis of anismus: dynamic endoanal echography.
    MeSH term(s) Anal Canal/diagnostic imaging ; Constipation/diagnostic imaging ; Constipation/etiology ; Defecation/physiology ; Humans ; Ultrasonography
    Language Spanish
    Publishing date 1996-11
    Publishing country Spain
    Document type Letter
    ZDB-ID 1070381-0
    ISSN 1130-0108 ; 0212-7512
    ISSN 1130-0108 ; 0212-7512
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  7. Article: Must ERCP Be routinely performed if choledocholithiasis is suspected?

    Hoyuela, C / Cugat, E / Bretcha, P / Collera, P / Espinós, J / Marco, C

    Digestive surgery

    1999  Volume 16, Issue 5, Page(s) 411–414

    Abstract: Objective: To evaluate the results of preoperative endoscopic retrograde cholangiopancreatography (ERCP) in the diagnosis and treatment of those patients suspected of harboring bile duct stones before laparoscopic cholecystectomy (LC).: Patients and ... ...

    Abstract Objective: To evaluate the results of preoperative endoscopic retrograde cholangiopancreatography (ERCP) in the diagnosis and treatment of those patients suspected of harboring bile duct stones before laparoscopic cholecystectomy (LC).
    Patients and methods: A total of 1,235 consecutive LCs performed between 1991 and 1997 were studied prospectively. ERCP was performed to explore the common bile duct (CBD) preoperatively when choledocholithiasis was suspected on the basis of clinical, analytical or echographical data.
    Results: ERCPs were performed in 268 patients: unsuccessful CBD evaluation in 3%; dilated CBD without lithiasis in 13%, and normal exploration in 37% (99 patients). CBD stones were found in 46% (124 patients), and endoscopic sphincterotomy was then performed and stone extraction attempted. Endoscopic therapy achieved 92.8% successful removal of CBD stones (115 patients). There was no ERCP-related mortality and the morbidity rate was 6%. Retained CBD stones have been observed in 7 cases after ERCP-LC; all of them have been successfully treated by ERCP.
    Conclusions: A combined approach to bile duct stones with selective use of ERCP followed by LC is a good therapeutical alternative. Nevertheless, the usual selection criteria for ERCP may lead to unnecessary exploration. It appears to be necessary to modify the current diagnostic and therapeutic strategy.
    MeSH term(s) Cholangiopancreatography, Endoscopic Retrograde ; Cholecystectomy, Laparoscopic ; Diagnostic Tests, Routine ; Gallstones/diagnostic imaging ; Humans ; Prospective Studies
    Language English
    Publishing date 1999
    Publishing country Switzerland
    Document type Clinical Trial ; Journal Article
    ZDB-ID 605888-7
    ISSN 1421-9883 ; 0253-4886
    ISSN (online) 1421-9883
    ISSN 0253-4886
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  8. Article: Retroperitoneal liposarcomas. Study of 10 cases.

    Muñoz, E / Sánchez, A / Collera, P / Bretcha, P / Forcada, P / Veloso, E / Marco, C

    Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva

    1998  Volume 90, Issue 4, Page(s) 269–274

    Abstract: Introduction: Retroperitoneal liposarcomas are unusual tumors. Their biological and clinical features different from other retroperitoneal sarcomas.: Aim: To analyze our series of retroperitoneal liposarcomas.: Patients and methods: Retrospective ... ...

    Abstract Introduction: Retroperitoneal liposarcomas are unusual tumors. Their biological and clinical features different from other retroperitoneal sarcomas.
    Aim: To analyze our series of retroperitoneal liposarcomas.
    Patients and methods: Retrospective study of 10 patients with retroperitoneal liposarcoma diagnosed in the last 16 years at our institution. Symptoms, diagnosis, treatment and prognosis were analyzed.
    Results: Radical resection was done in all cases. Postoperative mortality was 10%. Complementary treatment was considered in each patient. Recurrent disease occurred in 8 patients (14 recurrences), during follow up. In 42% of them recurrences were resected. Actuarial 5-year survival rate was 44%.
    Conclusion: Poor prognosis of retroperitoneal liposarcoma is due to its high recurrence rate.
    MeSH term(s) Adult ; Aged ; Female ; Humans ; Liposarcoma/diagnosis ; Liposarcoma/mortality ; Liposarcoma/surgery ; Male ; Middle Aged ; Prognosis ; Retroperitoneal Neoplasms/diagnosis ; Retroperitoneal Neoplasms/mortality ; Retroperitoneal Neoplasms/surgery ; Retrospective Studies
    Language Spanish
    Publishing date 1998-04
    Publishing country Spain
    Document type Journal Article
    ZDB-ID 1070381-0
    ISSN 1130-0108 ; 0212-7512
    ISSN 1130-0108 ; 0212-7512
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Aneurisma de la arteria pancreatoduodenal ántero-inferior como causa de hemorragia digestiva masiva.

    Muñoz, E / Rodríguez, J / Collera, P / Bretcha, P / Salas, A / Veloso, E / Marco, C

    Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva

    1997  Volume 89, Issue 8, Page(s) 638–639

    Abstract: We report a case of anterior inferior pancreaticoduodenal artery aneurysm fissured to the duodenum, which obliged to an emergency operation. This is an infrequent cause of upper gastrointestinal bleeding. Diagnosis, therapeutic options and prognosis of ... ...

    Title translation Aneurysm of the antero-inferior pancreatoduodenal artery as a cause of massive digestive hemorrhage.
    Abstract We report a case of anterior inferior pancreaticoduodenal artery aneurysm fissured to the duodenum, which obliged to an emergency operation. This is an infrequent cause of upper gastrointestinal bleeding. Diagnosis, therapeutic options and prognosis of this pathology are discussed.
    MeSH term(s) Aneurysm, Infected/complications ; Duodenal Diseases/etiology ; Gastrointestinal Hemorrhage/etiology ; Humans ; Male ; Middle Aged
    Language Spanish
    Publishing date 1997-08
    Publishing country Spain
    Document type Case Reports ; English Abstract ; Journal Article
    ZDB-ID 1070381-0
    ISSN 1130-0108 ; 0212-7512
    ISSN 1130-0108 ; 0212-7512
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  10. Article: Must ERCP Be Routinely Performed if Choledocholithiasis Is Suspected?

    Hoyuela, C. / Cugat, E. / Bretcha, P. / Collera, P. / Espinós, J. / Marco, C.

    Digestive Surgery

    1999  Volume 16, Issue 5, Page(s) 411–414

    Abstract: Objective: To evaluate the results of preoperative endoscopic retrograde cholangiopancreatography (ERCP) in the diagnosis and treatment of those patients suspected of harboring bile duct stones before laparoscopic cholecystectomy (LC). Patients and ... ...

    Institution Hepatobiliary and Pancreatic Surgery, Department of Surgery, Mútua de Terrassa Hospital, Terrassa, and University of Barcelona, Spain
    Abstract Objective: To evaluate the results of preoperative endoscopic retrograde cholangiopancreatography (ERCP) in the diagnosis and treatment of those patients suspected of harboring bile duct stones before laparoscopic cholecystectomy (LC). Patients and Methods: A total of 1,235 consecutive LCs performed between 1991 and 1997 were studied prospectively. ERCP was performed to explore the common bile duct (CBD) preoperatively when choledocholithiasis was suspected on the basis of clinical, analytical or echographical data. Results: ERCPs were performed in 268 patients: unsuccessful CBD evaluation in 3%; dilated CBD without lithiasis in 13%, and normal exploration in 37% (99 patients). CBD stones were found in 46% (124 patients), and endoscopic sphincterotomy was then performed and stone extraction attempted. Endoscopic therapy achieved 92.8% successful removal of CBD stones (115 patients). There was no ERCP-related mortality and the morbidity rate was 6%. Retained CBD stones have been observed in 7 cases after ERCP-LC; all of them have been successfully treated by ERCP. Conclusions: A combined approach to bile duct stones with selective use of ERCP followed by LC is a good therapeutical alternative. Nevertheless, the usual selection criteria for ERCP may lead to unnecessary exploration. It appears to be necessary to modify the current diagnostic and therapeutic strategy.
    Keywords Choledocholithiasis ; Cholelithiasis ; Endoscopic retrograde cholangiopancreatography ; Cholecystectomy ; Laparoscopy
    Language English
    Publishing date 1999-11-05
    Publisher S. Karger AG
    Publishing place Basel, Switzerland
    Document type Article
    Note Original Paper – Grassi Prize
    ZDB-ID 605888-7
    ISSN 1421-9883 ; 0253-4886
    ISSN (online) 1421-9883
    ISSN 0253-4886
    DOI 10.1159/000018757
    Database Karger publisher's database

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