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Book ; Online: Il welfare e il suo doppio

Colletti, Alessandro

2016

Abstract: Gran parte della produzione letteraria sulla camorra si sofferma sugli aspetti di controllo militare del territorio e sulle attività predatorie nella politica e nell'economia. Meno attenzione viene prestata ai fattori sociali di riproduzione dei gruppi ... ...

Abstract	Gran parte della produzione letteraria sulla camorra si sofferma sugli aspetti di controllo militare del territorio e sulle attività predatorie nella politica e nell'economia. Meno attenzione viene prestata ai fattori sociali di riproduzione dei gruppi di crimine organizzato. Gli aspetti di mutualità e solidarietà interna alle camorre non hanno mai ricevuto una sistematica e approfondita osservazione. Questa ricerca invece propone l'analisi degli elementi di legittimazione e di consenso dei gruppi di camorra nei territori in cui sono insediati. Il welfare e il suo doppio è un lavoro che si articola attraverso un ricco impianto che ricorre a metodologie quantitative ed etnografiche: un approccio situato al punto di incontro tra sociologia e antropologia nell'analisi delle politiche sociali, che utilizza documenti giudiziari inediti e di difficile reperibilità. Un impegnativo lavoro sul campo in territorio casertano ha permesso infatti di decifrare le forme di assistenza sociale presenti: quelle pubbliche e quelle mafiose. Ne emerge il panorama di un insieme criminale che assicura un'incredibile protezione nei confronti degli affiliati e delle loro famiglie, che concorre con le tutele offerte dal welfare pubblico.I risultati di questo studio mostrano però che è proprio nei territori più condizionati dalla presenza mafiosa che nascono nuove forme di lotta sociale. È qui, infatti - dove le infiltrazioni criminali interessano gli appalti dei servizi di welfare - che sono nate le più innovative azioni sociali in difesa delle categorie più deboli
Keywords	Communities. Classes. Races
Size	1 electronic resource (300 p.)
Publisher	Ledizioni - LediPublishing
Document type	Book ; Online
Note	Italian ; Open Access
HBZ-ID	HT020091265
ISBN	9788867054268 ; 8867054260
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Book ; Online ; E-Book: Handbook of nutraceuticals for clinical use

Cicero, Arrigo F. G. / Colletti, Alessandro

2018

Author's details	Arrigo F.G. Cicero, Alessandro Colletti
Keywords	Pharmacy ; Medicine ; Complementary medicine ; Clinical nutrition
Subject code	616.2
Language	English
Size	1 Online-Ressource (VII, 219 Seiten)
Publisher	Springer
Publishing place	Cham
Publishing country	Switzerland
Document type	Book ; Online ; E-Book
Remark	Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
HBZ-ID	HT019879788
ISBN	978-3-319-73642-6 ; 9783319736419 ; 3-319-73642-6 ; 3319736418
DOI	10.1007/978-3-319-73642-6
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: The Possible Role of Probiotic Supplementation in Inflammation: A Narrative Review.

Colletti, Alessandro / Pellizzato, Marzia / Cicero, Arrigo Francesco

Microorganisms

2023 Volume 11, Issue 9

Abstract: The fine balance between symbiotic and potentially opportunistic and/or pathogenic microorganisms can undergo quantitative alterations, which, when associated with low intestinal biodiversity, could be responsible for the development of gut inflammation ... ...

Abstract	The fine balance between symbiotic and potentially opportunistic and/or pathogenic microorganisms can undergo quantitative alterations, which, when associated with low intestinal biodiversity, could be responsible for the development of gut inflammation and the so-called "intestinal dysbiosis". This condition is characterized by the disbalance of a fine synergistic mechanism involving the mucosal barrier, the intestinal neuroendocrine system, and the immune system that results in an acute inflammatory response induced by different causes, including viral or bacterial infections of the digestive tract. More frequently, however, dysbiosis is induced slowly and subtly by subliminal causal factors, resulting in a chronic condition related to different diseases affecting the digestive tract and other organs and apparatuses. Studies on animal models, together with studies on humans, highlight the significant role of the gut microbiota and microbiome in the occurrence of inflammatory conditions such as metabolic syndrome and cardiovascular diseases (CVDs); neurodegenerative, urologic, skin, liver, and kidney pathologies; and premature aging. The blood translocation of bacterial fragments has been found to be one of the processes linked to gut dysbiosis and responsible for the possible occurrence of "metabolic endotoxemia" and systemic inflammation, associated with an increased risk of oxidative stress and related diseases. In this context, supplementation with different probiotic strains has been shown to restore gut eubiosis, especially if administered in long-term treatments. The aim of this review is to describe the anti-inflammatory effects of specific probiotic strains observed in clinical trials and the respective indications, highlighting the differences in efficacy depending on strain, formulation, time and duration of treatment, and dosage used.
Language	English
Publishing date	2023-08-26
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2720891-6
ISSN	2076-2607
ISSN	2076-2607
DOI	10.3390/microorganisms11092160
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Nutraceutical Approach to Chronic Osteoarthritis: From Molecular Research to Clinical Evidence.

Colletti, Alessandro / Cicero, Arrigo F G

International journal of molecular sciences

2021 Volume 22, Issue 23

Abstract: Osteoarthritis (OA) is a degenerative inflammatory condition of the joint cartilage that currently affects approximately 58 million adults in the world. It is characterized by pain, stiffness, and a reduced range of motion with regard to the arthritic ... ...

Abstract	Osteoarthritis (OA) is a degenerative inflammatory condition of the joint cartilage that currently affects approximately 58 million adults in the world. It is characterized by pain, stiffness, and a reduced range of motion with regard to the arthritic joints. These symptoms can cause in the long term a greater risk of overweight/obesity, diabetes mellitus, and falls and fractures. Although the current guidelines for the treatment of OA suggest, as the gold standard for this condition, pharmacological treatment characterized by non-steroidal anti-inflammatory drugs (NSAID), opioids, and cyclooxygenase (COX)-2-specific drugs, a great interest has been applied to nutraceutical supplements, which include a heterogeneous class of molecules with great potential to reduce inflammation, oxidative stress, pain, and joint stiffness and improve cartilage formation. The purpose of this review is to describe the potential application of nutraceuticals in OA, highlighting its molecular mechanisms of actions and data of efficacy and safety (when available).
MeSH term(s)	Chronic Disease/therapy ; Dietary Supplements ; Humans ; Osteoarthritis/diet therapy ; Osteoarthritis/prevention & control ; Secondary Prevention
Language	English
Publishing date	2021-11-29
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms222312920
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: An Evaluation of the Effects of Pineapple-Extract and Bromelain-Based Treatment after Mandibular Third Molar Surgery: A Randomized Three-Arm Clinical Study.

Colletti, Alessandro / Procchio, Chiara / Pisano, Mariaelena / Martelli, Alma / Pellizzato, Marzia / Cravotto, Giancarlo

Nutrients

2024 Volume 16, Issue 6

Abstract: A three-arm, randomized, placebo-controlled clinical study was conducted to assess the impact of lyophilized pineapple extract with titrated bromelain (Brome- ... ...

Abstract	A three-arm, randomized, placebo-controlled clinical study was conducted to assess the impact of lyophilized pineapple extract with titrated bromelain (Brome-Inf
MeSH term(s)	Humans ; Ibuprofen/therapeutic use ; Molar, Third/surgery ; Quality of Life ; Ananas ; Pain, Postoperative/drug therapy ; Bromelains/therapeutic use ; Trismus/drug therapy ; Trismus/etiology ; Trismus/prevention & control ; Anti-Inflammatory Agents/therapeutic use ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Edema/drug therapy ; Edema/etiology ; Edema/prevention & control ; Tooth Extraction/adverse effects
Chemical Substances	Ibuprofen (WK2XYI10QM) ; Bromelains (9001-00-7) ; Anti-Inflammatory Agents ; Anti-Inflammatory Agents, Non-Steroidal
Language	English
Publishing date	2024-03-09
Publishing country	Switzerland
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu16060784
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Nutraceutical Approaches to Dyslipidaemia: The Main Formulative Issues Preventing Efficacy.

Colletti, Alessandro / Fratter, Andrea / Pellizzato, Marzia / Cravotto, Giancarlo

Nutrients

2022 Volume 14, Issue 22

Abstract: Currently, the nutraceutical approach to treat dyslipidaemia is increasing in use, and in many cases is used by physicians as the first choice in the treatment of patients with borderline values. Nutraceuticals represent an excellent opportunity to treat ...

Abstract	Currently, the nutraceutical approach to treat dyslipidaemia is increasing in use, and in many cases is used by physicians as the first choice in the treatment of patients with borderline values. Nutraceuticals represent an excellent opportunity to treat the preliminary conditions not yet showing the pathological signs of dyslipidaemia. Their general safety, the patient's confidence, the convincing proof of efficacy and the reasonable costs prompted the market of new preparations. Despite this premise, many nutraceutical products are poorly formulated and do not meet the minimum requirements to ensure efficacy in normalizing blood lipid profiles, promoting cardiovascular protection, and normalizing disorders of glycemic metabolism. In this context, bioaccessibility and bioavailability of the active compounds is a crucial issue. Little attention is paid to the proper formulations needed to improve the overall bioavailability of the active molecules. According to these data, many products prove to be insufficient to ensure full enteric absorption. The present review analysed the literature in the field of nutraceuticals for the treatment of dyslipidemia, focusing on resveratrol, red yeast rice, berberine, and plant sterols, which are among the nutraceuticals with the greatest formulation problems, highlighting bioavailability and the most suitable formulations.
MeSH term(s)	Humans ; Dyslipidemias/prevention & control ; Dietary Supplements ; Phytosterols ; Lipids ; Berberine
Chemical Substances	Phytosterols ; Lipids ; Berberine (0I8Y3P32UF)
Language	English
Publishing date	2022-11-11
Publishing country	Switzerland
Document type	Journal Article ; Review
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu14224769
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Short-Term Effect of Nutraceutical Fruit Juices on Lipid Metabolism in Patients with Acquired Hypercholesterolemia.

Ardissino, Diego / Colletti, Alessandro / Pellizzato, Marzia / Pagliari, Gianna / Di Pierro, Francesco / Cravotto, Giancarlo

International journal of molecular sciences

2023 Volume 24, Issue 8

Abstract: The crucial role of dyslipidaemia, especially hypercholesterolemia, in the development of atherosclerosis-related cardiovascular diseases has been extensively documented in genetic, pathologic, observational and intervention studies. The European ... ...

Abstract	The crucial role of dyslipidaemia, especially hypercholesterolemia, in the development of atherosclerosis-related cardiovascular diseases has been extensively documented in genetic, pathologic, observational and intervention studies. The European guidelines for dyslipidaemia management include the possible use of lipid-lowering nutraceuticals to support a relatively large number of natural compounds. In this context, we have conducted a study to investigate whether dietary supplementation with a functional nutraceutical beverage, containing a standardized polyphenolic fraction from fruit, red yeast rice, phytosterols, and berberine complexed with β-cyclodextrin, could positively affect serum lipid concentration in 14 subjects with hypercholesterolemia. After 12 weeks of treatment, dietary supplementation with this nutraceutical combination was associated with significant improvements in total cholesterol, low-density lipoprotein cholesterol, non-high-density lipoprotein cholesterol (non-HDL-C) and apolipoprotein B, compared to baseline. Compliance was excellent and no adverse effects were reported. In conclusion, this study demonstrates that 100 mL of a functional beverage containing lipid-lowering nutraceuticals safely leads to significant improvements in serum lipids in subjects with moderate hypercholesterolemia. Future research is needed to unravel the role that the polyphenols contained in fruit extracts play in the reduction of cholesterolemia and in cardiovascular disease prevention.
MeSH term(s)	Humans ; Hypercholesterolemia/complications ; Fruit and Vegetable Juices ; Lipid Metabolism ; Dietary Supplements/adverse effects ; Cholesterol ; Dyslipidemias/drug therapy ; Dyslipidemias/complications
Chemical Substances	Cholesterol (97C5T2UQ7J)
Language	English
Publishing date	2023-04-16
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2019364-6
ISSN	1422-0067 ; 1422-0067 ; 1661-6596
ISSN (online)	1422-0067
ISSN	1422-0067 ; 1661-6596
DOI	10.3390/ijms24087358
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: An update on the safety of nutraceuticals and effects on lipid parameters.

Cicero, Arrigo F G / Colletti, Alessandro

Expert opinion on drug safety

2018 Volume 17, Issue 3, Page(s) 303–313

Abstract: Introduction: Cardiovascular diseases (CVDs) are the leading cause of mortality and disability in developed countries, whereas a large portion of patients in primary prevention have uncontrolled level of CVD risk factors. Dietary supplementation with ... ...

Abstract	Introduction: Cardiovascular diseases (CVDs) are the leading cause of mortality and disability in developed countries, whereas a large portion of patients in primary prevention have uncontrolled level of CVD risk factors. Dietary supplementation with bioactive natural compounds with demonstrated lipid-lowering effects is currently supported by the international guidelines for CVD prevention and some international expert panels. Areas covered: This review provides insights on issues concerning the tolerability and safety of the most commonly used nutraceuticals with demonstrated lipid-lowering effect in humans. They will be then divided into three main categories according to their mechanism of action (cholesterol synthesis inhibitors, intestinal cholesterol absorption inhibitors, and LDL-C excretion stimulants) and their pharmacological profile will be discussed. Expert opinion: A growing body of preclinical, epidemiological and clinical evidence has defined the tolerability and safety profile of the most commonly used lipid-lowering nutraceuticals. In the most part of cases, the side effects are mild and reversible. However, detailed knowledge of specific health risks and pharmacological interactions for each individual compound is needed for the management of frail patients, such as children, elderly, patients with liver or renal failure, and patients consuming numerous drugs.
MeSH term(s)	Aged ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/prevention & control ; Child ; Cholesterol/metabolism ; Cholesterol, LDL/metabolism ; Dietary Supplements/adverse effects ; Humans ; Lipids/blood ; Practice Guidelines as Topic ; Primary Prevention/methods ; Risk Factors
Chemical Substances	Cholesterol, LDL ; Lipids ; Cholesterol (97C5T2UQ7J)
Language	English
Publishing date	2018-01-29
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2088728-0
ISSN	1744-764X ; 1474-0338
ISSN (online)	1744-764X
ISSN	1474-0338
DOI	10.1080/14740338.2018.1429404
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Nutraceuticals as Modulators of Immune Function: A Review of Potential Therapeutic Effects.

Medoro, Alessandro / Davinelli, Sergio / Colletti, Alessandro / Di Micoli, Valentina / Grandi, Elisa / Fogacci, Federica / Scapagnini, Giovanni / Cicero, Arrigo F G

Preventive nutrition and food science

2023 Volume 28, Issue 2, Page(s) 89–107

Abstract: Dietary supplementation with nutraceuticals can promote optimal immune system activation, modulating different pathways that enhance immune defenses. Therefore, the immunity-boosting effects of nutraceuticals encompass not only immunomodulatory but also ... ...

Abstract	Dietary supplementation with nutraceuticals can promote optimal immune system activation, modulating different pathways that enhance immune defenses. Therefore, the immunity-boosting effects of nutraceuticals encompass not only immunomodulatory but also antioxidant, antitumor, antiviral, antibacterial, and antifungal properties, with therapeutic effects against diverse pathological conditions. However, the complexity of the pathways that regulate the immune system, numerous mechanisms of action, and heterogeneity of the immunodeficiencies, and subjects treated make their application in the clinical field difficult. Some nutraceuticals appear to safely improve immune system function, particularly by preventing viral and bacterial infections in specific groups, such as children, the elderly, and athletes, as well as in frail patients, such as those affected by autoimmune diseases, chronic diseases, or cancer. Several nutraceuticals, such as vitamins, mineral salts, polyunsaturated omega-3 fatty acids, many types of phytocompounds, and probiotic strains, have the most consolidated evidence in humans. In most cases, further large and long-term randomized clinical trials are needed to confirm the available preliminary positive data.
Language	English
Publishing date	2023-06-28
Publishing country	Korea (South)
Document type	Journal Article ; Review
ZDB-ID	2668373-8
ISSN	2287-8602 ; 2287-1098
ISSN (online)	2287-8602
ISSN	2287-1098
DOI	10.3746/pnf.2023.28.2.89
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Article ; Online: Polyphenols Effect on Circulating Lipids and Lipoproteins: From Biochemistry to Clinical Evidence.

Cicero, Arrigo F G / Colletti, Alessandro

Current pharmaceutical design

2017 Volume 24, Issue 2, Page(s) 178–190

Abstract: Background: Polyphenols are a family of natural antioxidants that in recent years have been studied and tested for their potential benefits towards cardiovascular diseases.: Objective: The aim of this review is to focus the attention on the presumed ... ...

Abstract	Background: Polyphenols are a family of natural antioxidants that in recent years have been studied and tested for their potential benefits towards cardiovascular diseases. Objective: The aim of this review is to focus the attention on the presumed lipid-lowering and atheroprotective effects of polyphenols, administered either as individual molecules (nutritional supplements) and as functional foods, on the basis of the evidence coming from randomized controlled trials (RCTs) and their meta-analyses. Method: A search strategy was conducted to identify studies in PubMed (January 1980 to September 2016); in particular, we have included human clinical trials, reviews and meta-analyses when they offered suitable insights and elucidations regarding the action of polyphenols on lipid profile and cardiovascular disease risk. Results: Literature data on polyphenols suggest that they potentially could exert an effect on lipid profile, especially by reducing the oxidation of LDL-C. Polyphenols from cocoa, grape, green tea, berries and soy are the ones that have shown more clinically relevant effect. However, quantitative data on cholesterol reduction are still unclear and often conflicting. Conclusion: Polyphenols, if taken in adequate dosages, can exert in some cases a positive effect on the prevention of cardiovascular risk and lipid oxidation, despite an unclear effect on lipid levels.
MeSH term(s)	Animals ; Cardiovascular Diseases/prevention & control ; Humans ; Lipid Peroxidation/drug effects ; Lipids/blood ; Lipoproteins/blood ; Polyphenols/pharmacology
Chemical Substances	Lipids ; Lipoproteins ; Polyphenols
Language	English
Publishing date	2017-11-30
Publishing country	United Arab Emirates
Document type	Journal Article ; Review
ZDB-ID	1304236-1
ISSN	1873-4286 ; 1381-6128
ISSN (online)	1873-4286
ISSN	1381-6128
DOI	10.2174/1381612824666171128110408
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