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Article ; Online: Patient Communications: Why Is It Important to Quickly Use Epinephrine at the Onset of Symptoms and Signs of Anaphylaxis?

Collie, James C / Lockey, Richard F

Immunology and allergy clinics of North America

2021  Volume 42, Issue 1, Page(s) 201–217

Abstract: Delayed administration of epinephrine (adrenaline), the first-line and only effective treatment of a systemic allergic reaction (SAR) and anaphylaxis, is associated with increased mortality. However, epinephrine is underused because of a lack of ... ...

Abstract Delayed administration of epinephrine (adrenaline), the first-line and only effective treatment of a systemic allergic reaction (SAR) and anaphylaxis, is associated with increased mortality. However, epinephrine is underused because of a lack of consensus as to when it should be administered and an inappropriate fear of using epinephrine and potential adverse effects from the medication. The authors emphasize that SARs and anaphylaxis should be considered as a spectrum, and that affected individuals be educated on its safety and repeatedly given instructions as to when and how epinephrine should be used at the first symptoms or signs of SAR and anaphylaxis.
MeSH term(s) Anaphylaxis/diagnosis ; Epinephrine ; Humans ; Treatment Outcome
Chemical Substances Epinephrine (YKH834O4BH)
Language English
Publishing date 2021-11-22
Publishing country United States
Document type Journal Article ; Review
ZDB-ID 92606-1
ISSN 1557-8607 ; 0889-8561
ISSN (online) 1557-8607
ISSN 0889-8561
DOI 10.1016/j.iac.2021.09.009
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