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  1. Article ; Online: A pilot test of the Self-Management and Research Technology project: A text message-based diabetes self-management program for adolescents.

    Herbert, Linda Jones / Collier, Suzanne / Stern, Alexa / Monaghan, Maureen / Streisand, Randi

    Journal of child health care : for professionals working with children in the hospital and community

    2016  Volume 20, Issue 4, Page(s) 456–463

    Abstract: The aims of this study are to: (1) examine the preliminary utility of the Self-Management and Research Technology (SMART) pilot project, (2) identify which adolescents were most likely to benefit from participation, and (3) examine interview feedback to ... ...

    Abstract The aims of this study are to: (1) examine the preliminary utility of the Self-Management and Research Technology (SMART) pilot project, (2) identify which adolescents were most likely to benefit from participation, and (3) examine interview feedback to inform future program iterations. Twenty-three adolescents ( M
    Language English
    Publishing date 2016-07-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 2299167-0
    ISSN 1741-2889 ; 1367-4935
    ISSN (online) 1741-2889
    ISSN 1367-4935
    DOI 10.1177/1367493515603829
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Trends in GH use in a Turner syndrome natural history study.

    Gutin, Liat / Collier, Suzanne / Bakalov, Vladimir K / Bondy, Carolyn

    Pediatric endocrinology reviews : PER

    2012  Volume 9 Suppl 2, Page(s) 725–727

    Abstract: The present observations are derived from 273 girls and women aged 7-40 years participating in the National Institutes of Health natural history study of Turner syndrome (TS) in the interval 2001-2011. There was a higher percentage of GH use among ... ...

    Abstract The present observations are derived from 273 girls and women aged 7-40 years participating in the National Institutes of Health natural history study of Turner syndrome (TS) in the interval 2001-2011. There was a higher percentage of GH use among individuals in the pediatric age group (7-17, n = 118, 83%) compared to young adult women with prior GH use (18-40, n = 155, 61%). The major factor in this divergence seems to be a trend toward earlier diagnosis of TS in the younger age group. We find a striking association between history of GH use and lower total body and abdominal fat mass in young adults with TS approximately one decade after discontinuation of GH treatment. The interpretation of this observation is limited by the fact that our study subjects were not randomly assigned to GH treatment. There may be a bias involving poor health care, childhood obesity, delayed diagnosis, absent GH treatment and persistent adult obesity. Further studies on the socioeconomic factors implicated in patterns of GH use and non-use for girls with TS are needed to illuminate this important issue.
    MeSH term(s) Abdominal Fat ; Adolescent ; Adult ; Body Height/drug effects ; Child ; Drug Therapy/trends ; Female ; Growth Hormone/therapeutic use ; Humans ; Retrospective Studies ; Turner Syndrome/drug therapy
    Chemical Substances Growth Hormone (9002-72-6)
    Language English
    Publishing date 2012-09-03
    Publishing country Israel
    Document type Journal Article
    ZDB-ID 2434390-0
    ISSN 1565-4753
    ISSN 1565-4753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Cortical bone mineral density in patients with congenital adrenal hyperplasia due to 21-hydroxylase deficiency.

    El-Maouche, Diala / Collier, Suzanne / Prasad, Mala / Reynolds, James C / Merke, Deborah P

    Clinical endocrinology

    2014  Volume 82, Issue 3, Page(s) 330–337

    Abstract: Background: Prior studies reveal that bone mineral density (BMD) in congenital adrenal hyperplasia (CAH) is mostly in the osteopaenic range and is associated with lifetime glucocorticoid dose. The forearm, a measure of cortical bone density, has not ... ...

    Abstract Background: Prior studies reveal that bone mineral density (BMD) in congenital adrenal hyperplasia (CAH) is mostly in the osteopaenic range and is associated with lifetime glucocorticoid dose. The forearm, a measure of cortical bone density, has not been evaluated.
    Objective: We aimed to evaluate BMD at various sites, including the forearm, and the factors associated with low BMD in CAH patients.
    Methods: Eighty CAH adults (47 classic, 33 nonclassic) underwent dual-energy-x-ray absorptiometry and laboratory and clinical evaluation. BMD Z-scores at the AP spine, total hip, femoral neck, forearm and whole body were examined in relation to phenotype, body mass index, current glucocorticoid dose, average 5-year glucocorticoid dose, vitamin D, 17-hydroxyprogesterone, androstenedione, testosterone, dehydroepiandrosterone and dehydroepiandrosterone sulphate (DHEAS).
    Results: Reduced BMD (T-score <-1 at hip, spine, or forearm) was present in 52% and was more common in classic than nonclassic patients (P = 0·005), with the greatest difference observed at the forearm (P = 0·01). Patients with classic compared to nonclassic CAH, had higher 17-hydroxyprogesterone (P = 0·005), lower DHEAS (P = 0·0002) and higher non-traumatic fracture rate (P = 0·0005). In a multivariate analysis after adjusting for age, gender, height standard deviation, phenotype and cumulative glucocorticoid exposure, higher DHEAS was independently associated with higher BMD at the spine, radius and whole body.
    Conclusion: Classic CAH patients have lower BMD than nonclassic patients, with the most affected area being the forearm. This first study of forearm BMD in CAH patients suggests that low DHEAS may be associated with weak cortical bone independent of glucocorticoid exposure.
    MeSH term(s) Absorptiometry, Photon ; Adrenal Hyperplasia, Congenital/drug therapy ; Adrenal Hyperplasia, Congenital/pathology ; Adult ; Bone Density/physiology ; Female ; Femur Neck/drug effects ; Femur Neck/metabolism ; Forearm ; Glucocorticoids/therapeutic use ; Humans ; Male ; Middle Aged ; Multivariate Analysis ; Pelvic Bones/drug effects ; Pelvic Bones/metabolism ; Spine/drug effects ; Spine/metabolism ; Young Adult
    Chemical Substances Glucocorticoids
    Language English
    Publishing date 2014-06-28
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Intramural
    ZDB-ID 121745-8
    ISSN 1365-2265 ; 0300-0664
    ISSN (online) 1365-2265
    ISSN 0300-0664
    DOI 10.1111/cen.12507
    Database MEDical Literature Analysis and Retrieval System OnLINE

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