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  1. Article ; Online: Is Subthalamic Nucleus Deep Brain Stimulation Efficacious in Treating Axial Symptoms in Patients with a Suboptimal Levodopa Response?

    Onder, Halil / Comoglu, Selcuk

    Turkish neurosurgery

    2024  Volume 34, Issue 1, Page(s) 171

    MeSH term(s) Humans ; Levodopa/therapeutic use ; Subthalamic Nucleus/surgery ; Subthalamic Nucleus/physiology ; Deep Brain Stimulation ; Parkinson Disease/drug therapy ; Antiparkinson Agents/therapeutic use
    Chemical Substances Levodopa (46627O600J) ; Antiparkinson Agents
    Language English
    Publishing date 2024-01-29
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 1203779-5
    ISSN 2651-5032 ; 1019-5149
    ISSN (online) 2651-5032
    ISSN 1019-5149
    DOI 10.5137/1019-5149.JTN.44315-23.2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4081: Show issues Location:
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  2. Article ; Online: Investigation of the nonmotor symptoms in patients with STN-DBS therapy in comparison with those without STN-DBS.

    Onder, Halil / Comoglu, Selcuk

    Journal of neural transmission (Vienna, Austria : 1996)

    2024  

    Abstract: The impact of STN-DBS on NMS remains rather as an underestimated topic. Besides, the significance of NMSs in QOL indexes of PD subjects with STN-DBS is unknown. We primarily aimed to evaluate the NMSs and their significance in QOL indexes in PD subjects ... ...

    Abstract The impact of STN-DBS on NMS remains rather as an underestimated topic. Besides, the significance of NMSs in QOL indexes of PD subjects with STN-DBS is unknown. We primarily aimed to evaluate the NMSs and their significance in QOL indexes in PD subjects comparatively with and without STN-DBS therapy. We enrolled all consecutive PD subjects with and without STN-DBS who applied to our movement disorders outpatient clinics between January/2023 and September/2023. We performed comprehensive assessments of the motor and nonmotor features including the clinical scales of Movement Disorder Society-sponsored revision of the MDS-UPDRS, NMSS, HAM-A, HAM-D, and the PDQ-39. Overall, 48 PD subjects with STN-DBS and 161 without STN-DBS treatment were included. The comparative analyses revealed that the sub-scores of the MDS-UPDRS-2, -3 and -4 were higher in the STN-DBS group. However, the MDS-UDPRS-1 and the total scores of the NMSS were similar between groups. Among eight subitems of the NMSS, only, the sub scores of the mood/cognition and the gastrointestinal tract differed. Remarkably, the significant correlations between the scores of the QOL and the NMSS scores in the STN-DBS (-) group, did not persist within the STN-DBS group. Remarkably, the correlations between the NMSS and PQQ-39 disappeared for most of the sub scores within the STN-DBS group. We found indirect evidence regarding the benefit of STN-DBS therapy on NMSs in our cross-sectional study. Besides, we found weaker impact of NMSs in QOL indexes in PD subjects with STN-DBS therapy.
    Language English
    Publishing date 2024-04-30
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 184163-4
    ISSN 1435-1463 ; 0300-9564
    ISSN (online) 1435-1463
    ISSN 0300-9564
    DOI 10.1007/s00702-024-02778-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui II Zs.150: Show issues Location:
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  3. Article: A Rare Case of Reversible Splenial Lesion Syndrome with Extracallosal Lesions in the Setting of Deep Anemia.

    Onder, Halil / Comoglu, Selcuk

    Asian journal of neurosurgery

    2023  Volume 18, Issue 3, Page(s) 684–687

    Language English
    Publishing date 2023-09-22
    Publishing country India
    Document type Journal Article
    ZDB-ID 2621446-5
    ISSN 2248-9614 ; 1793-5482
    ISSN (online) 2248-9614
    ISSN 1793-5482
    DOI 10.1055/s-0043-1771320
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: A Rare Patient with Hereditary Spastic Paraparesis with Parkinsonism.

    Onder, Halil / Comoglu, Selcuk

    Asian journal of neurosurgery

    2023  Volume 18, Issue 1, Page(s) 216–218

    Abstract: Herein, we present a rare patient with hereditary spastic paraparesis (HSP) in whom significant parkinsonism was involved in the clinic. Besides, the dopamine transport single-photon emission computed tomography scan also showed decreased tracer uptake ... ...

    Abstract Herein, we present a rare patient with hereditary spastic paraparesis (HSP) in whom significant parkinsonism was involved in the clinic. Besides, the dopamine transport single-photon emission computed tomography scan also showed decreased tracer uptake in the bilateral striatum. Via the presentation of this patient, we discuss the parkinsonian findings in patients with HSP. We think that the observations of dopaminergic neuron vulnerability in HSP patients raise the possibility that degeneration of central dopaminergic neurons may contribute to the phenotype of HSP. The documentation of these rare variants will aid to understand the unknown pathophysiology of the disease course.
    Language English
    Publishing date 2023-04-03
    Publishing country India
    Document type Case Reports
    ZDB-ID 2621446-5
    ISSN 2248-9614 ; 1793-5482
    ISSN (online) 2248-9614
    ISSN 1793-5482
    DOI 10.1055/s-0043-1764117
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Controlled-Release Levodopa for the Treatment of Rapid Motor Fluctuations in Parkinson's Disease Subjects with Subthalamic Nucleus Deep Brain Stimulation.

    Onder, Halil / Comoglu, Selcuk

    Asian journal of neurosurgery

    2023  Volume 18, Issue 2, Page(s) 321–326

    Abstract: ... ...

    Abstract Objectives
    Language English
    Publishing date 2023-06-16
    Publishing country India
    Document type Journal Article
    ZDB-ID 2621446-5
    ISSN 2248-9614 ; 1793-5482
    ISSN (online) 2248-9614
    ISSN 1793-5482
    DOI 10.1055/s-0043-1769757
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Resting and re-emergent jaw tremor as the presenting symptom of Parkinson's disease.

    Onder, Halil / Comoglu, Selcuk

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2023  Volume 45, Issue 1, Page(s) 329–330

    MeSH term(s) Humans ; Parkinson Disease/complications ; Parkinson Disease/diagnosis ; Tremor/diagnosis ; Tremor/etiology ; Rest
    Language English
    Publishing date 2023-09-23
    Publishing country Italy
    Document type Letter
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-023-07041-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1877: Show issues Location:
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  7. Article ; Online: Alternating unilateral blepharospasm with apraxia of eyelid opening in a patient with progressive supranuclear palsy.

    Onder, Halil / Comoglu, Selcuk

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2023  Volume 45, Issue 1, Page(s) 331–333

    MeSH term(s) Humans ; Blepharospasm/complications ; Supranuclear Palsy, Progressive/complications ; Supranuclear Palsy, Progressive/diagnostic imaging ; Eyelids ; Apraxias/complications ; Apraxias/diagnostic imaging ; Eyelid Diseases
    Language English
    Publishing date 2023-09-22
    Publishing country Italy
    Document type Letter
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-023-07021-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1877: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
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    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Letter regarding the article entitled: 'Normal Pressure Hydrocephalus Overshadowed by Traumatic and Degenerative Spinal Diseases: A New Assessment Proposal'.

    Onder, Halil / Comoglu, Selcuk

    Turkish neurosurgery

    2023  Volume 33, Issue 5, Page(s) 919–920

    MeSH term(s) Humans ; Hydrocephalus, Normal Pressure/complications ; Hydrocephalus, Normal Pressure/surgery ; Spinal Diseases ; Spine
    Language English
    Publishing date 2023-08-23
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 1203779-5
    ISSN 2651-5032 ; 1019-5149
    ISSN (online) 2651-5032
    ISSN 1019-5149
    DOI 10.5137/1019-5149.JTN.44299-23.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4081: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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  9. Article: Deep Brain Stimulation of the Subthalamic Nucleus and the Postoperative Levodopa Response?

    Onder, Halil / Comoglu, Selcuk

    Turkish neurosurgery

    2023  Volume 33, Issue 1, Page(s) 176

    MeSH term(s) Humans ; Levodopa/therapeutic use ; Subthalamic Nucleus/surgery ; Subthalamic Nucleus/physiology ; Deep Brain Stimulation ; Parkinson Disease/drug therapy ; Parkinson Disease/surgery ; Antiparkinson Agents/therapeutic use
    Chemical Substances Levodopa (46627O600J) ; Antiparkinson Agents
    Language English
    Publishing date 2023-01-09
    Publishing country Turkey
    Document type Journal Article
    ZDB-ID 1203779-5
    ISSN 1019-5149
    ISSN 1019-5149
    DOI 10.5137/1019-5149.JTN.37641-22.1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4081: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  10. Article ; Online: Investigation of the factors associated with hemichorea/hemiballismus in post-stroke patients.

    Onder, Halil / Comoglu, Selcuk

    Journal of neural transmission (Vienna, Austria : 1996)

    2023  Volume 130, Issue 5, Page(s) 679–685

    Abstract: Classical knowledge highlights the role of lesions of the subthalamic nuclei (STN) in the pathophysiology of hemichorea/hemiballismus (HH). However, the published reports indicate various other lesion regions in the majority of post-stroke cases with HH. ...

    Abstract Classical knowledge highlights the role of lesions of the subthalamic nuclei (STN) in the pathophysiology of hemichorea/hemiballismus (HH). However, the published reports indicate various other lesion regions in the majority of post-stroke cases with HH. Ergo, we aimed to investigate the significance of the lesion site and clinical features for developing HH in post-stroke patients. Overall, we retrospectively scanned all the patients with stroke who were hospitalized between 01/06/2022 and 31/07/2022 in our neurology clinic. The data regarding the demographic features, comorbidities, stroke etiologies, and laboratory findings, including serum glucose and HBA1C were retrospectively recruited using the electronic-based medical record system. The cranial magnetic resonance imaging (MRI) and computed tomography images have been systematically evaluated for the presence of lesions in localizations that are previously associated with HH. We conducted comparative analyses between patients with and without HH to reveal the discrepancies between groups. The logistic regression analyses were also performed to reveal the predictive values of some features. Overall, the data of 124 post-stroke patients were analyzed. The mean age was 67.9 ± 12.4 years (F/M = 57/67). Six patients were determined to develop HH. The comparative analyses between patients with and without HH revealed that the mean age tended to be higher in the HH group (p = 0.08) and caudate nucleus involvement was more common in the HH group (p = 0.005). Besides cortical involvement was absent in all subjects developing HH. The logistic regression model revealed the presence of a caudate lesion and advanced age as factors associated with HH. We found that the caudate lesion was a crucial determinant of the occurrence of HH in post-stroke patients. With the significance of the other factors of increased age and cortical sparring, we observed differences in the HH group may be investigated also in future-related studies on larger groups.
    MeSH term(s) Humans ; Middle Aged ; Aged ; Aged, 80 and over ; Retrospective Studies ; Dyskinesias/diagnostic imaging ; Dyskinesias/etiology ; Chorea/diagnostic imaging ; Chorea/epidemiology ; Chorea/etiology ; Stroke/complications ; Stroke/diagnostic imaging ; Magnetic Resonance Imaging
    Language English
    Publishing date 2023-04-03
    Publishing country Austria
    Document type Journal Article
    ZDB-ID 184163-4
    ISSN 1435-1463 ; 0300-9564
    ISSN (online) 1435-1463
    ISSN 0300-9564
    DOI 10.1007/s00702-023-02628-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui II Zs.150: Show issues Location:
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