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  1. Book ; Conference proceedings: Résumés des rapports et des communications / XXXIIIes Journées Angiologiques de Langue Française ; XXXIIIe Cours de Perfectionnement sur les Maladies des Vaisseaux Périphériques

    Conard, Jacqueline

    Paris 18, 19, 20 mars 1998

    (Journal des maladies vasculaires ; 24, Suppl. A ; Congrès du Collège Français de Pathologie Vasculaire ; 33)

    1999  

    Event/congress Journées Angiologiques de Langue Française (33, 1999, Paris) ; Cours de Perfectionnement sur les Maladies des Vaisseaux Périphériques (35, 1999, Paris)
    Author's details président du congrès: Jacqueline Conard
    Series title Journal des maladies vasculaires ; 24, Suppl. A
    Congrès du Collège Français de Pathologie Vasculaire ; 33
    Congrès du Collège Francais de Pathologie Vasculaire
    Collection Congrès du Collège Francais de Pathologie Vasculaire
    Language French ; English
    Size 121 S.
    Publisher Masson
    Publishing place Paris u.a.
    Publishing country France
    Document type Book ; Conference proceedings
    Note Text. engl. und franz.
    HBZ-ID HT010295405
    Database Catalogue ZB MED Medicine, Health

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  2. Article: Thrombophilie et grossesse: quel bilan pour quelles patientes? Le point de vue du biologiste.

    Conard, Jacqueline

    Annales de medecine interne

    2003  Volume 154, Issue 5-6, Page(s) 340–344

    Abstract: Pregnancy is associated with an increased risk of venous thromboembolism, especially in women with a congenital predisposition. The detection of these thrombophilias, with an autosomal dominant transmission, is justified if an appropriate prophylaxis is ... ...

    Title translation Thrombophilia and pregnancy: who should be tested? Which tests should be performed? The biologist point of view.
    Abstract Pregnancy is associated with an increased risk of venous thromboembolism, especially in women with a congenital predisposition. The detection of these thrombophilias, with an autosomal dominant transmission, is justified if an appropriate prophylaxis is administered during pregnancy and/or post-partum. The aim of the prophylaxis is to prevent thrombotic events and possibly adverse pregnancy complications, such as pregnancy loss at the second or third trimester, intra-uterine fetal growth retardation or pre-eclampsia. The magnitude of the pregnancy-associated risk in the different thrombophilias is taken into account for the selection of the patients to be tested for the detection of thrombophilia. Tests to be performed are proposed and their interpretation depends on whether the patient is pregnant, receiving oral contraception or oral anticoagulants.
    MeSH term(s) Female ; Humans ; Pregnancy ; Pregnancy Complications, Hematologic/diagnosis ; Thrombophilia/diagnosis
    Language French
    Publishing date 2003-09
    Publishing country France
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 215082-7
    ISSN 0003-410X
    ISSN 0003-410X
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Type of Combined Contraceptives, Factor V Leiden Mutation and Risk of Venous Thromboembolism.

    Hugon-Rodin, Justine / Horellou, Marie-Hélène / Conard, Jacqueline / Gompel, Anne / Plu-Bureau, Geneviève

    Thrombosis and haemostasis

    2018  Volume 118, Issue 5, Page(s) 922–928

    Abstract: Objective: This article estimates the interaction between types of combined hormonal contraception (CHC) and factor V Leiden (FVL) mutation on the risk of venous thrombosis event (VTE).: Subjects and methods: All premenopausal women with first ... ...

    Abstract Objective: This article estimates the interaction between types of combined hormonal contraception (CHC) and factor V Leiden (FVL) mutation on the risk of venous thrombosis event (VTE).
    Subjects and methods: All premenopausal women with first incident VTE who were referred to our unit (Paris, France) between 2000 and 2009 were included in this case-only study. Differences in interactions by progestin type were assessed on a multiplicative scale, assuming the independence of genotype and prescription of type of CHC.
    Results: Among 2,613 women with VTE, 15.9% had a FVL and 69% used CHC. The interaction between CHC use and presence of FVL on VTE risk was statistically significant (1.37, 1.06-1.77 95% confidence interval [CI]). This interaction appeared higher for drospirenone 1.99 (1.18-3.38 95% CI) (
    Conclusion: Our results show that the interaction between FVL and CHC use differ by progestin type, which is higher in CHC containing third-generation progestin, drospirenone or cyproterone acetate, compared with second generation. Further studies are needed to assess the cost-effectiveness of biological thrombophilia screening (FVL) when such prescription of CHC is planned.
    MeSH term(s) Adolescent ; Adult ; Androstenes/adverse effects ; Blood Coagulation Disorders, Inherited/blood ; Blood Coagulation Disorders, Inherited/diagnosis ; Blood Coagulation Disorders, Inherited/epidemiology ; Blood Coagulation Disorders, Inherited/genetics ; Contraceptives, Oral, Combined/adverse effects ; Contraceptives, Oral, Hormonal/adverse effects ; Cyproterone Acetate/adverse effects ; Factor V/genetics ; Female ; Humans ; Incidence ; Middle Aged ; Paris/epidemiology ; Premenopause/blood ; Progestins/adverse effects ; Risk Factors ; Venous Thromboembolism/chemically induced ; Venous Thromboembolism/diagnosis ; Venous Thromboembolism/epidemiology ; Venous Thromboembolism/genetics ; Young Adult
    Chemical Substances Androstenes ; Contraceptives, Oral, Combined ; Contraceptives, Oral, Hormonal ; Progestins ; factor V Leiden ; Cyproterone Acetate (4KM2BN5JHF) ; Factor V (9001-24-5) ; drospirenone (N295J34A25)
    Language English
    Publishing date 2018-04-03
    Publishing country Germany
    Document type Comparative Study ; Journal Article
    ZDB-ID 518294-3
    ISSN 2567-689X ; 0340-6245
    ISSN (online) 2567-689X
    ISSN 0340-6245
    DOI 10.1055/s-0038-1641152
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Combined Hormonal Contraceptives and First Venous Thrombosis in Young French Women: Impact of Thrombotic Family History.

    Hugon-Rodin, Justine / Horellou, Marie-Hélène / Conard, Jacqueline / Gompel, Anne / Plu-Bureau, Geneviève

    Journal of the Endocrine Society

    2017  Volume 1, Issue 6, Page(s) 762–771

    Abstract: Context: In UK and French, but not World Health Organization (WHO), guidelines for combined hormonal contraception (CHC), family history of a venous thromboembolism (VTE) is a condition for which the theoretical risks usually outweigh the advantages of ... ...

    Abstract Context: In UK and French, but not World Health Organization (WHO), guidelines for combined hormonal contraception (CHC), family history of a venous thromboembolism (VTE) is a condition for which the theoretical risks usually outweigh the advantages of using CHC.
    Objective: We estimated the prevalence of inappropriate prescriptions of CHC according to several international guidelines and their impact on VTE.
    Design: A single-center observational study.
    Setting: Hemostasis unit outpatient clinic (Paris, France).
    Population: A total of 2088 French CHC users of childbearing age with a first documented VTE who were referred to our unit between 2000 and 2009.
    Methods: Data were collected by a standardized questionnaire during a medical consultation. Family history of VTE was analyzed according to definitions from international recommendations (VTE before age 45 years, United Kingdom; before age 50 years, France). A CHC prescription was considered inappropriate for women with vascular contraindications and/or a family history of VTE. Cross-sectional analysis of the clinical and biological characteristics was performed.
    Main outcome measures: Prevalence of inappropriate prescription of CHC and potentially preventable events were estimated.
    Results: According to the WHO, UK, or French guidelines, 8.8%, 18.9%, and 25.9%, respectively, of CHC prescriptions were considered inappropriate. Compliance with these guidelines could reduce the corresponding number of VTEs by 6.3%, 13.5%, and 18.5%, respectively. Characteristics of the women were similar.
    Conclusion: Our results suggest inappropriate CHC prescriptions are prevalent among CHC users with first VTE. The appropriate way to take family history of VTE into account should be further clarified.
    Language English
    Publishing date 2017-04-20
    Publishing country United States
    Document type Journal Article
    ISSN 2472-1972
    ISSN 2472-1972
    DOI 10.1210/js.2017-00090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Grossesse, contraception, THS et maladie thrombo-embolique veineuse.

    Conard, Jacqueline / Gompel, Anne

    La Revue du praticien

    2007  Volume 57, Issue 7, Page(s) 759–766

    Abstract: Endogeneous and exogeneous hormonal factors may favor venous thromboembolism (VTE) in the woman. Pregnancy and post-partum, combined contraception and hormonal replacement therapy (HRT) of menopause are associated with an increased risk of VTE. Even when ...

    Title translation Pregnancy, contraception and HRT and venous thromboembolism.
    Abstract Endogeneous and exogeneous hormonal factors may favor venous thromboembolism (VTE) in the woman. Pregnancy and post-partum, combined contraception and hormonal replacement therapy (HRT) of menopause are associated with an increased risk of VTE. Even when the relative risk is statistically significant, the absolute risk remains generally low unless additional factors are present. The occurrence of a thrombosis depends on the conditions associated to these risk factors: multiparity, caesarean section, type of contraception or HRT, and also on risk factors associated to the woman such as age, obesity, personal history of VTE, hereditary or acquired thrombophilia. The detection of high-risk women because of personal history of VTE, associated risk factors and/or thrombophilia should improve the clinical management and thrombosis prophylaxis, especially when hormonal treatments are prescribed.
    MeSH term(s) Age Factors ; Cesarean Section ; Contraceptives, Oral, Hormonal/adverse effects ; Female ; Hormone Replacement Therapy/adverse effects ; Humans ; Menopause ; Obesity/complications ; Parity ; Postpartum Period ; Pregnancy ; Pregnancy Complications ; Puerperal Disorders/etiology ; Risk Factors ; Thromboembolism/etiology ; Thromboembolism/prevention & control ; Thrombophilia/complications ; Thrombophilia/genetics ; Venous Thrombosis/etiology ; Venous Thrombosis/prevention & control
    Chemical Substances Contraceptives, Oral, Hormonal
    Language French
    Publishing date 2007-04-15
    Publishing country France
    Document type English Abstract ; Journal Article
    ZDB-ID 205365-2
    ISSN 2101-017X ; 0035-2640
    ISSN (online) 2101-017X
    ISSN 0035-2640
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Type of Combined Contraceptives, Factor V Leiden Mutation and Risk of Venous Thromboembolism

    Hugon-Rodin, Justine / Horellou, Marie-Hélène / Conard, Jacqueline / Gompel, Anne / Plu-Bureau, Geneviève

    Thrombosis and Haemostasis

    2018  Volume 118, Issue 05, Page(s) 922–928

    Abstract: Objective: This article estimates the interaction between types of combined hormonal contraception (CHC) and factor V Leiden (FVL) mutation on the risk of venous thrombosis event (VTE).: Subjects and Methods: All premenopausal women with first ... ...

    Abstract Objective: This article estimates the interaction between types of combined hormonal contraception (CHC) and factor V Leiden (FVL) mutation on the risk of venous thrombosis event (VTE).
    Subjects and Methods: All premenopausal women with first incident VTE who were referred to our unit (Paris, France) between 2000 and 2009 were included in this case-only study. Differences in interactions by progestin type were assessed on a multiplicative scale, assuming the independence of genotype and prescription of type of CHC.
    Results: Among 2,613 women with VTE, 15.9% had a FVL and 69% used CHC. The interaction between CHC use and presence of FVL on VTE risk was statistically significant (1.37, 1.06–1.77 95% confidence interval [CI]). This interaction appeared higher for drospirenone 1.99 (1.18–3.38 95% CI) ( n  = 98) or cyproterone acetate users 1.71 (1.20–2.45 95% CI) ( n  = 326), but not significant for 1st or 2nd or norgestimate CHC users. The results were similar when excluding women with a family history of VTE or with provoked VTE. In this sub-group of women, these interactions appeared higher for third generation, cyproterone acetate and drospirenone CHC users as compared with 1st or 2nd or norgestimate CHC users (odds ratio [OR], 1.68 [1.04–2.70; 95% CI], 2.91 [1.71–4.95 95% CI], 3.22 [1.54–6.73 95% CI], respectively).
    Conclusion: Our results show that the interaction between FVL and CHC use differ by progestin type, which is higher in CHC containing third-generation progestin, drospirenone or cyproterone acetate, compared with second generation. Further studies are needed to assess the cost-effectiveness of biological thrombophilia screening (FVL) when such prescription of CHC is planned.
    Keywords venous thrombosis ; combined contraception ; factor V Leiden mutation ; epidemiology
    Language English
    Publishing date 2018-04-03
    Publisher Schattauer GmbH
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 518294-3
    ISSN 2567-689X ; 0340-6245
    ISSN (online) 2567-689X
    ISSN 0340-6245
    DOI 10.1055/s-0038-1641152
    Database Thieme publisher's database

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  7. Article ; Online: Coagulation Characterization of Prothrombin 20209C > T Variant: About 27 New Cases.

    Jourdi, Georges / Lobies, Sophie / Kosmider, Olivier / Duchemin, Jérôme / Audureau, Etienne / Conard, Jacqueline / Mazoyer, Elisabeth / Horellou, Marie-Hélène / Gouin-Thibault, Isabelle / Flaujac, Claire / Fontenay, Michaëla

    Thrombosis and haemostasis

    2020  Volume 121, Issue 2, Page(s) 246–249

    MeSH term(s) Adult ; Blood Coagulation ; Female ; Genetic Variation ; Humans ; Male ; Middle Aged ; Polymorphism, Single Nucleotide ; Prothrombin/genetics ; Retrospective Studies ; Venous Thromboembolism/blood ; Venous Thromboembolism/genetics
    Chemical Substances Prothrombin (9001-26-7)
    Language English
    Publishing date 2020-09-15
    Publishing country Germany
    Document type Letter
    ZDB-ID 518294-3
    ISSN 2567-689X ; 0340-6245
    ISSN (online) 2567-689X
    ISSN 0340-6245
    DOI 10.1055/s-0040-1716541
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  8. Book ; Thesis: 'Twixt cup and lip

    Conard, Jacqueline Mary

    the evolution of product evaluations

    2003  

    Author's details by Jacqueline M. Conard
    Keywords Produktinformation ; Konsumentenverhalten
    Language English
    Size XVI, 133 S., graph. Darst.
    Publisher UMI Diss. Services
    Publishing place Ann Arbor, Mich
    Document type Book ; Thesis
    Thesis / German Habilitation thesis NC, Duke Univ., Dep. of Business Administration, Diss.--Durham, 2003
    Note Kopie, ersch. im Verl. UMI, Ann Arbor, Mich.
    Database ECONomics Information System

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  9. Article ; Online: Risk assessment models for thromboprophylaxis of medical patients.

    Samama, Meyer M / Combe, Sophie / Conard, Jacqueline / Horellou, Marie-Helene

    Thrombosis research

    2012  Volume 129, Issue 2, Page(s) 127–132

    MeSH term(s) Humans ; Outcome Assessment (Health Care)/methods ; Prevalence ; Prognosis ; Proportional Hazards Models ; Risk Assessment/methods ; Risk Factors ; Thrombosis/epidemiology ; Thrombosis/prevention & control
    Language English
    Publishing date 2012-02
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Review
    ZDB-ID 121852-9
    ISSN 1879-2472 ; 0049-3848
    ISSN (online) 1879-2472
    ISSN 0049-3848
    DOI 10.1016/j.thromres.2011.09.025
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  10. Article: Coagulation Characterization of Prothrombin 20209C > T Variant: About 27 New Cases

    Jourdi, Georges / Lobies, Sophie / Kosmider, Olivier / Duchemin, Jérôme / Audureau, Etienne / Conard, Jacqueline / Mazoyer, Elisabeth / Horellou, Marie-Hélène / Gouin-Thibault, Isabelle / Flaujac, Claire / Fontenay, Michaëla

    Thrombosis and Haemostasis

    2020  Volume 121, Issue 02, Page(s) 246–249

    Language English
    Publishing date 2020-09-15
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 518294-3
    ISSN 2567-689X ; 0340-6245
    ISSN (online) 2567-689X
    ISSN 0340-6245
    DOI 10.1055/s-0040-1716541
    Database Thieme publisher's database

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