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Article ; Online: Comment on "Radiation Doses and Risks in Breast Screening".

Conners, Amy Lynn / Ellis, Richard / Fazzio, Robert T / Hruska, Carrie B / Hunt, Katie N / O'Connor, Michael K / Rhodes, Deborah J / Shermis, Robin

Journal of breast imaging

2024 Volume 2, Issue 6, Page(s) 519–520

Language	English
Publishing date	2024-02-29
Publishing country	United States
Document type	Journal Article
ISSN	2631-6129
ISSN (online)	2631-6129
DOI	10.1093/jbi/wbaa074
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Article ; Online: PPV of the Molecular Breast Imaging Lexicon.

Hunt, Katie N / Conners, Amy Lynn / Samreen, Naziya / Rhodes, Deborah / Johnson, Matthew P / Hruska, Carrie B

AJR. American journal of roentgenology

2022

Abstract: Background: ...

Abstract	Background:
Language	English
Publishing date	2022-07-20
Publishing country	United States
Document type	Journal Article
ZDB-ID	82076-3
ISSN	1546-3141 ; 0361-803X ; 0092-5381
ISSN (online)	1546-3141
ISSN	0361-803X ; 0092-5381
DOI	10.2214/AJR.21.27047
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Article ; Online: Molecular Breast Imaging in Patients with Suspicious Calcifications.

Hunt, Katie N / Hruska, Carrie B / Johnson, Matthew P / Conners, Amy Lynn / O'connor, Michael K / Rhodes, Deborah J / Basappa, Susanna / Wahner-Roedler, Dietlind

Journal of breast imaging

2024 Volume 1, Issue 4, Page(s) 303–309

Abstract: Objective: We evaluated the accuracy of molecular breast imaging (MBI)-a nuclear medicine technique that employs dedicated dual-detector, cadmium zinc telluride gamma cameras to image the functional uptake of a radiopharmaceutical (typically Tc-99m ... ...

Abstract	Objective: We evaluated the accuracy of molecular breast imaging (MBI)-a nuclear medicine technique that employs dedicated dual-detector, cadmium zinc telluride gamma cameras to image the functional uptake of a radiopharmaceutical (typically Tc-99m sestamibi) in the breast-in patients with suspicious calcifications on mammography. Methods: Women scheduled for stereotactic biopsy of calcifications detected on 2D digital mammography were prospectively enrolled to undergo MBI before biopsy. Molecular breast imaging was performed with injection of Tc-99m sestamibi and a dual-detector, cadmium zinc telluride gamma camera. Positive findings on either modality were biopsied. High-risk and malignant biopsy findings were excised. Results: In 71 participants, 76 areas of calcifications were recommended for biopsy after mammography, and 24 (32%) were malignant, including 20 cases of ductal carcinoma in situ (DCIS) and 4 cases of invasive ductal cancer. Prebiopsy MBI was positive in 17 of the 76 (22%) calcifications, including 10 of 20 (50%) DCISs and 2 of 4 (50%) invasive cancers. The median pathologic size for MBI-positive cancers was 1.5 cm (range 0.5-3.2 cm) compared with 0.9 cm (range 0.1-2.0 cm) for MBI-negative cancers (P = 0.09).Non-mass uptake on MBI led to additional biopsies of 6 sites in 6 patients, and 2 of 6 (33%) MBI-detected incidental lesions showed malignancy; both DCIS contralateral to the mammographically detected calcifications. The overall per-lesion positive and negative predictive values of MBI in this prebiopsy setting were 61% (14 of 23) and 80% (47 of 59), respectively. Conclusion: Molecular breast imaging has insufficient negative predictive value to identify calcifications in which biopsy could be avoided. However, among women presenting for biopsy of suspicious calcifications, MBI revealed additional sites of mammographically occult breast cancer.To avoid biopsy of suspicious calcifications on mammography, negative findings on MBI should not be used.
Language	English
Publishing date	2024-02-29
Publishing country	United States
Document type	Journal Article
ISSN	2631-6129
ISSN (online)	2631-6129
DOI	10.1093/jbi/wbz054
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Article ; Online: Assessment of MRI-detected lesions on screening tomosynthesis in patients with newly diagnosed breast cancer.

Choudhery, Sadia / Polley, Eric / Conners, Amy Lynn

Clinical imaging

2019 Volume 59, Issue 1, Page(s) 50–55

Abstract: Objectives: The purpose of this study is to retrospectively evaluate the presence of screening digital breast tomosynthesis (DBT) correlates for suspicious lesions detected on pre-operative staging magnetic resonance imaging (MRI) in patients with newly ...

Abstract	Objectives: The purpose of this study is to retrospectively evaluate the presence of screening digital breast tomosynthesis (DBT) correlates for suspicious lesions detected on pre-operative staging magnetic resonance imaging (MRI) in patients with newly diagnosed breast cancer. Methods: After approval from the institutional review board (IRB), screening DBTs on breast cancer patients with BI-RADS 4 or 5 staging MRI exams between 8/1/17 and 8/1/18 were assessed for presence of DBT correlates for suspicious MRI findings. The pathology of the index lesion, type of additional MRI finding (mass, non-mass enhancement, or focus), correlative finding on tomosynthesis (mass, asymmetry/focal asymmetry, distortion, or calcifications), size on MRI and tomosynthesis, breast density, and pathology of the additional lesion were recorded. The chi-square test of association was used unless otherwise specified. Confidence intervals for proportions were estimated using the Wilson's score method. Results: 17/70 (24%) of additional lesions seen on pre-operative MRI exams in patients with newly diagnosed cancer had a mammographic correlate on corresponding screening DBT. There was no significant relationship between the presence of a mammographic correlate and the type of MRI finding (mass, NME, or focus), breast density, size of lesion, pathology of index cancer, or pathology of the additional lesion (p≥ 0.05). Conclusions: 76% of additional lesions seen on pre-operative staging MRI in patients with newly diagnosed breast cancer are not seen retrospectively on screening DBT. Since about 24% of MRI-detected additional lesions may have a DBT correlate, DBT exams should be reviewed in patients recalled for further workup of findings seen on pre-operative MRI since this may facilitate DBT-guided biopsy of suspicious lesions, which is preferable to MRI-guided biopsy for cost and patient comfort reasons.
MeSH term(s)	Adult ; Aged ; Breast Carcinoma In Situ/pathology ; Breast Density/physiology ; Breast Neoplasms/pathology ; Carcinoma, Ductal, Breast/pathology ; Early Detection of Cancer/methods ; Female ; Humans ; Image-Guided Biopsy/methods ; Magnetic Resonance Imaging/methods ; Mammography/methods ; Middle Aged ; Retrospective Studies
Language	English
Publishing date	2019-11-11
Publishing country	United States
Document type	Evaluation Study ; Journal Article
ZDB-ID	1028123-x
ISSN	1873-4499 ; 0899-7071
ISSN (online)	1873-4499
ISSN	0899-7071
DOI	10.1016/j.clinimag.2019.09.007
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Article ; Online: Basics of time-driven activity-based costing (TDABC) and applications in breast imaging.

Choudhery, Sadia / Hanson, Amber L / Stellmaker, Jessica A / Ness, Jaysen / Chida, Linda / Conners, Amy Lynn

The British journal of radiology

2020 Volume 94, Issue 1119, Page(s) 20201138

Abstract: Time-drive activity-based costing (TDABC) is a practical way of calculating costs, decreasing waste, and improving efficiency. Although TDABC has been utilized in other service industries for years, it has only recently gained attention in healthcare. In ...

Abstract	Time-drive activity-based costing (TDABC) is a practical way of calculating costs, decreasing waste, and improving efficiency. Although TDABC has been utilized in other service industries for years, it has only recently gained attention in healthcare. In this review article, we define the basic concepts and steps of TDABC and provide examples for applications in breast imaging.
MeSH term(s)	Breast/diagnostic imaging ; Breast Neoplasms/diagnostic imaging ; Breast Neoplasms/economics ; Cost-Benefit Analysis/economics ; Cost-Benefit Analysis/methods ; Cost-Benefit Analysis/statistics & numerical data ; Health Care Costs/statistics & numerical data ; Humans ; Radiology/economics ; Radiology/methods
Language	English
Publishing date	2020-12-04
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2982-8
ISSN	1748-880X ; 0007-1285
ISSN (online)	1748-880X
ISSN	0007-1285
DOI	10.1259/bjr.20201138
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Article: Breast density legislation. Implications for patients and primary care providers.

Rhodes, Deborah J / Conners, Amy Lynn

Minnesota medicine

2014 Volume 97, Issue 7, Page(s) 43–48

Abstract: Minnesota recently became the 16th state to require facilities that perform mammograms to notify patients if they are found to have dense or extremely dense breasts, as this may make it more difficult to detect a cancer or put them at increased risk for ... ...

Abstract	Minnesota recently became the 16th state to require facilities that perform mammograms to notify patients if they are found to have dense or extremely dense breasts, as this may make it more difficult to detect a cancer or put them at increased risk for cancer. This article outlines the new law and describes the classification system for breast density, the implications for breast density on screening mammography, and the relationship between breast density and cancer. It also provides guidance for patients who have dense breast tissue regarding supplementary screening.
MeSH term(s)	Breast/pathology ; Female ; Humans ; Mammography ; Mass Screening/legislation & jurisprudence ; Minnesota ; Patient Education as Topic/legislation & jurisprudence ; Sensitivity and Specificity
Language	English
Publishing date	2014-07
Publishing country	United States
Document type	Journal Article
ZDB-ID	391068-4
ISSN	1945-3051 ; 0026-556X
ISSN (online)	1945-3051
ISSN	0026-556X
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Article: Tiger-Striped PASH: Recognition of a Unique Morphology Allows for a Zippered-Up Diagnosis of Pseudoangiomatous Stromal Hyperplasia of Breast.

Sakibuzzaman, Mohamad / Kendziora, Ryan W / Ghosh, Toshi / Solanki, Malvika H / Conners, Amy Lynn / Ahlberg, Lisa J / Sturgis, Charles D

Case reports in pathology

2021 Volume 2021, Page(s) 7697987

Abstract: Pseudoangiomatous stromal hyperplasia (PASH) of the breast is histologically characterized by anastomosing and slit-like spaces invested by collagenous stroma and lined by flattened, spindle cells. These clear spaces that may mimic microscopic vascular ... ...

Abstract	Pseudoangiomatous stromal hyperplasia (PASH) of the breast is histologically characterized by anastomosing and slit-like spaces invested by collagenous stroma and lined by flattened, spindle cells. These clear spaces that may mimic microscopic vascular channels do not contain red blood cells. Immunohistochemistry (IHC) studies may also help to confirm a diagnosis of PASH, with the spindled cells marking positively with CD34 and PR while demonstrating no reactivity with more specific endothelial antigens such as CD31 and ERG. In the current case, a 39-year-old female was diagnosed with cellular PASH of the right breast with unique histological patterns showing "tiger-striped" and "zippered" histologies. To our knowledge, this is the first report of these unique variant PASH morphologies.
Language	English
Publishing date	2021-12-26
Publishing country	United States
Document type	Case Reports
ZDB-ID	2648758-5
ISSN	2090-679X ; 2090-6781
ISSN (online)	2090-679X
ISSN	2090-6781
DOI	10.1155/2021/7697987
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Article ; Online: Utilizing Time-Driven Activity-Based Costing to Increase Efficiency in Ultrasound-Guided Breast Biopsy Practice.

Choudhery, Sadia / Stellmaker, Jessica A / Hanson, Amber L / Ness, Jaysen / Chida, Linda / Johnson, Bryana / Conners, Amy Lynn

Journal of the American College of Radiology : JACR

2020 Volume 17, Issue 1 Pt B, Page(s) 131–136

Abstract: Purpose: In this study, we used time-driven activity-based costing to increase efficiency in our ultrasound-guided breast biopsy practice by understanding costs associated with this procedure.: Methods: We assembled a multidisciplinary team of all ... ...

Abstract	Purpose: In this study, we used time-driven activity-based costing to increase efficiency in our ultrasound-guided breast biopsy practice by understanding costs associated with this procedure. Methods: We assembled a multidisciplinary team of all relevant stakeholders involved in ultrasound-guided breast biopsies, including a radiologist, a lead technologist, a clinical assistant, a licensed practical nurse, and a procedural support assistant. The team mapped each step in an ultrasound-guided breast biopsy from the time of scheduling a biopsy to patient checkout. We completed on average 20 time observations of each step involved in these biopsies from a provider's perspective. Using capacity cost rate, we calculated the cost of all resources including personnel, supply, room, and equipment costs. Several costly steps were identified in the process, which led to the intervention of changing our overlapping biopsy times to staggered biopsy times. Time observations for each step and cost calculations were repeated postintervention. Results: Our postintervention data showed that the total time spent by the radiologist in an ultrasound breast biopsy decreased by 28%, accounting for 56% of the total cost in comparison with 63% pre-intervention. The radiologist's wait time decreased by 38%, accounting for 28% of the total cost in comparison with 35% pre-intervention. Our total cost of the procedure decreased by 20%, and the personnel cost decreased by 25%. Conclusions: Time-driven activity-based costing is a practical way to calculate costs and identify non-value-added steps, which can foster strategies to improve efficiency and minimize waste.
MeSH term(s)	Breast Neoplasms/pathology ; Cost-Benefit Analysis ; Efficiency, Organizational/economics ; Episode of Care ; Female ; Humans ; Image-Guided Biopsy/economics ; Process Assessment, Health Care/economics ; Time Factors ; Ultrasonography, Interventional/economics
Language	English
Publishing date	2020-02-03
Publishing country	United States
Document type	Journal Article
ZDB-ID	2274861-1
ISSN	1558-349X ; 1546-1440
ISSN (online)	1558-349X
ISSN	1546-1440
DOI	10.1016/j.jacr.2019.06.016
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Article ; Online: Masses in the era of screening tomosynthesis: Is diagnostic ultrasound sufficient?

Choudhery, Sadia / Axmacher, Jessica / Conners, Amy Lynn / Geske, Jennifer / Brandt, Kathy

The British journal of radiology

2018 Volume 92, Issue 1095, Page(s) 20180801

Abstract: Methods:: All masses recalled from screening digital breast tomosynthesis between July 1, 2017 and December 31, 2017 that were sent either to diagnostic mammography or ultrasound were compared. Size, shape, margins, visibility on ultrasound, diagnostic ... ...

Abstract	Methods:: All masses recalled from screening digital breast tomosynthesis between July 1, 2017 and December 31, 2017 that were sent either to diagnostic mammography or ultrasound were compared. Size, shape, margins, visibility on ultrasound, diagnostic assessment and pathology of all masses along with breast density were evaluated. Results:: 102/212 digital breast tomosynthesis screen-detected masses were worked up with diagnostic mammography initially and 110/212 were worked up with ultrasound directly. There was no significant difference in ultrasound visibility of masses sent to diagnostic mammography first with those sent to ultrasound first (p = 0.42). 4 (4%) masses sent to mammogram first and 2 (2%) masses sent to ultrasound first were not visualized. There was a significant difference in size between masses that were visualized under ultrasound versus those that were not (p = 0.01), when masses in both groups were assessed cumulatively. Conclusions:: 98% of digital breast tomosynthesis screen-detected masses sent to ultrasound directly were adequately assessed without diagnostic mammography. Advances in knowledge:: There is potential for avoiding a diagnostic mammogram for evaluation of majority of digital breast tomosynthesis screen-detected masses.
MeSH term(s)	Breast/diagnostic imaging ; Breast/pathology ; Breast Neoplasms/diagnostic imaging ; Early Detection of Cancer/methods ; Early Detection of Cancer/statistics & numerical data ; Female ; Humans ; Mammography/methods ; Mammography/statistics & numerical data ; Middle Aged ; Retrospective Studies ; Sensitivity and Specificity ; Ultrasonography, Mammary/methods ; Ultrasonography, Mammary/statistics & numerical data
Language	English
Publishing date	2018-12-17
Publishing country	England
Document type	Journal Article
ZDB-ID	2982-8
ISSN	1748-880X ; 0007-1285
ISSN (online)	1748-880X
ISSN	0007-1285
DOI	10.1259/bjr.20180801
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Article ; Online: Background Parenchymal Uptake on Molecular Breast Imaging and Breast Cancer Risk: A Cohort Study.

Hruska, Carrie B / Geske, Jennifer R / Conners, Amy Lynn / Whaley, Dana H / Rhodes, Deborah J / O'Connor, Michael K / Carter, Rickey E / Scott, Christopher G / Vachon, Celine M

AJR. American journal of roentgenology

2021 Volume 216, Issue 5, Page(s) 1193–1204

Abstract: BACKGROUND. ...

Abstract	BACKGROUND.
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Breast/diagnostic imaging ; Breast Density ; Breast Neoplasms/diagnostic imaging ; Cohort Studies ; Female ; Humans ; Mammography/methods ; Middle Aged ; Molecular Imaging/methods ; Parenchymal Tissue/diagnostic imaging ; Reproducibility of Results ; Retrospective Studies
Language	English
Publishing date	2021-03-03
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	82076-3
ISSN	1546-3141 ; 0361-803X ; 0092-5381
ISSN (online)	1546-3141
ISSN	0361-803X ; 0092-5381
DOI	10.2214/AJR.20.23854
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