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Article ; Online: Low dose inocula of SARS-CoV-2 Alpha variant transmits more efficiently than earlier variants in hamsters

Bobo Wing-Yee Mok / Honglian Liu / Shaofeng Deng / Jiayan Liu / Anna Jinxia Zhang / Siu-Ying Lau / Siwen Liu / Rachel Chun-Yee Tam / Conor J. Cremin / Timothy Ting-Leung Ng / Jake Siu-Lun Leung / Lam-Kwong Lee / Pui Wang / Kelvin Kai-Wang To / Jasper Fuk-Woo Chan / Kwok-Hung Chan / Kwok-Yung Yuen / Gilman Kit-Hang Siu / Honglin Chen

Communications Biology, Vol 4, Iss 1, Pp 1-

2021  Volume 8

Abstract: Bobo Wing-Yee Mok et al. observe that the Alpha (B.1.1.7) variant of SARS-CoV-2 exhibits increased competitive fitness over earlier lineages at lower doses in a hamster model of viral transmission. Their results suggest that the Alpha variant’s ability ... ...

Abstract Bobo Wing-Yee Mok et al. observe that the Alpha (B.1.1.7) variant of SARS-CoV-2 exhibits increased competitive fitness over earlier lineages at lower doses in a hamster model of viral transmission. Their results suggest that the Alpha variant’s ability to initiate effective infection with a low dose may underlie its ability to rapidly transmit throughout a population.
Keywords Biology (General) ; QH301-705.5
Language English
Publishing date 2021-09-01T00:00:00Z
Publisher Nature Portfolio
Document type Article ; Online
Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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