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  1. Article ; Online: Oral care with chlorhexidine: One size does not fit all.

    Llaurado-Serra, M / Afonso, E / Mellinghoff, J / Conoscenti, E / Deschepper, M

    Enfermeria intensiva

    2023  Volume 34, Issue 4, Page(s) 227–228

    MeSH term(s) Chlorhexidine ; Anti-Infective Agents, Local ; Mouthwashes
    Chemical Substances Chlorhexidine (R4KO0DY52L) ; Anti-Infective Agents, Local ; Mouthwashes
    Language English
    Publishing date 2023-12-01
    Publishing country Spain
    Document type Letter
    ISSN 2529-9840
    ISSN (online) 2529-9840
    DOI 10.1016/j.enfie.2023.08.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: How to deal with gender inequality among ICU clinicians? Uno, nessuno e centomila "issues".

    Rubulotta, Francesca / Conoscenti, Elena / Sharma, Deeya

    Intensive & critical care nursing

    2023  Volume 76, Page(s) 103380

    MeSH term(s) Humans ; Gender Equity ; Intensive Care Units
    Language English
    Publishing date 2023-02-02
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1105892-4
    ISSN 1532-4036 ; 0964-3397
    ISSN (online) 1532-4036
    ISSN 0964-3397
    DOI 10.1016/j.iccn.2022.103380
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Less daily oral hygiene is more in the ICU: not sure.

    Labeau, S O / Conoscenti, E / Blot, S I

    Intensive care medicine

    2020  Volume 47, Issue 3, Page(s) 334–336

    MeSH term(s) Humans ; Infection Control ; Intensive Care Units ; Oral Hygiene ; Pneumonia, Ventilator-Associated
    Keywords covid19
    Language English
    Publishing date 2020-04-01
    Publishing country United States
    Document type Editorial
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0340-0964 ; 0342-4642 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0340-0964 ; 0342-4642 ; 0935-1701
    DOI 10.1007/s00134-020-06021-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Why to monitor adherence to oral care protocols in intensive care units?

    Blot, Stijn / Conoscenti, Elena

    Australian critical care : official journal of the Confederation of Australian Critical Care Nurses

    2021  Volume 36, Issue 2, Page(s) 169–170

    MeSH term(s) Humans ; Intensive Care Units ; Critical Care/methods ; Guideline Adherence
    Language English
    Publishing date 2021-12-31
    Publishing country Australia
    Document type Letter ; Comment
    ZDB-ID 1159493-7
    ISSN 1878-1721 ; 1036-7314
    ISSN (online) 1878-1721
    ISSN 1036-7314
    DOI 10.1016/j.aucc.2021.12.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A necessary evil: Central venous catheters.

    Conoscenti, Elena / Blot, Stijn

    Intensive & critical care nursing

    2020  Volume 57, Page(s) 102810

    MeSH term(s) Bibliometrics ; Catheterization, Central Venous ; Central Venous Catheters ; Humans
    Language English
    Publishing date 2020-02-03
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 1105892-4
    ISSN 1532-4036 ; 0964-3397
    ISSN (online) 1532-4036
    ISSN 0964-3397
    DOI 10.1016/j.iccn.2020.102810
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Combination antimicrobial therapy in Pseudomonas aeruginosa bacteremia.

    Afonso, Elsa / Conoscenti, Elena / Blot, Stijn

    European journal of pediatrics

    2020  Volume 179, Issue 12, Page(s) 1997–1998

    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Anti-Infective Agents ; Bacteremia/drug therapy ; Child ; Humans ; Pseudomonas Infections/drug therapy ; Pseudomonas aeruginosa ; Retrospective Studies ; Sepsis/drug therapy
    Chemical Substances Anti-Bacterial Agents ; Anti-Infective Agents
    Language English
    Publishing date 2020-07-23
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 194196-3
    ISSN 1432-1076 ; 0340-6199 ; 0943-9676
    ISSN (online) 1432-1076
    ISSN 0340-6199 ; 0943-9676
    DOI 10.1007/s00431-020-03748-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Good habits from the pandemic age to bring home: Effective communication and briefing tools.

    Conoscenti, Elena / Blot, Stijn / Lombardo, Rosario / Campanella, Maria / Luca, Angelo

    Intensive & critical care nursing

    2021  Volume 65, Page(s) 103056

    MeSH term(s) Communication ; Habits ; Humans ; Pandemics/prevention & control ; Patient Care Team
    Language English
    Publishing date 2021-04-17
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 1105892-4
    ISSN 1532-4036 ; 0964-3397
    ISSN (online) 1532-4036
    ISSN 0964-3397
    DOI 10.1016/j.iccn.2021.103056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Mobile phones as a vector for Healthcare-Associated Infection: A systematic review.

    De Groote, Pauwel / Blot, Koen / Conoscenti, Elena / Labeau, Sonia / Blot, Stijn

    Intensive & critical care nursing

    2022  Volume 72, Page(s) 103266

    Abstract: Introduction: Mobile phones have become indispensable accessories of both our social and professional lives. They increase the quality of healthcare by providing fast communication, and easy access to laboratory results, imaging and patients' files. ... ...

    Abstract Introduction: Mobile phones have become indispensable accessories of both our social and professional lives. They increase the quality of healthcare by providing fast communication, and easy access to laboratory results, imaging and patients' files. Simultaneously however, they may act as vectors for potentially pathogenic micro-organisms and as such hold a potential risk for nosocomial infection.
    Objectives: To assess the risk of mobile phones as vectors for nosocomial infection and the impact of disinfecting mobile phones on infection risks.
    Methods: The MEDLINE and Embase database were searched from January 2000 - January 2019 for a systematic review according to PRISMA guidelines. Eligible studies of any design were critically appraised by two independent reviewers.
    Results: We identified 50 studies, of which 12 were interventional. Data for a total of 5425 microbiological samples resulted in a prevalence of potentially pathogenic micro-organisms from 0% to 100%. The 2 most commonly found micro-organisms were coagulase-negative staphylococci (most commonly found in 30 studies) and Staphylococcus aureus (most commonly found in 10 studies). The frequency of microbial growth varied across studies.
    Conclusions: The use of mobile phones by healthcare workers without proper disinfection may imply a risk for nosocomial infection. A direct relationship however, remains unproven. Healthcare workers are recommended to include proper handling of mobile phones in their 'classic' hand hygiene routine as proposed by the World Health Organisation.
    MeSH term(s) Cell Phone ; Cross Infection/microbiology ; Cross Infection/prevention & control ; Delivery of Health Care ; Hand Hygiene ; Health Personnel ; Humans
    Language English
    Publishing date 2022-06-07
    Publishing country Netherlands
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 1105892-4
    ISSN 1532-4036 ; 0964-3397
    ISSN (online) 1532-4036
    ISSN 0964-3397
    DOI 10.1016/j.iccn.2022.103266
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Endocrine Challenges in Patients with Continuous-Flow Left Ventricular Assist Devices.

    Martucci, Gennaro / Pappalardo, Federico / Subramanian, Harikesh / Ingoglia, Giulia / Conoscenti, Elena / Arcadipane, Antonio

    Nutrients

    2021  Volume 13, Issue 3

    Abstract: Heart failure (HF) remains a leading cause of morbidity, hospitalization, and mortality worldwide. Advancement of mechanical circulatory support technology has led to the use of continuous-flow left ventricular assist devices (LVADs), reducing ... ...

    Abstract Heart failure (HF) remains a leading cause of morbidity, hospitalization, and mortality worldwide. Advancement of mechanical circulatory support technology has led to the use of continuous-flow left ventricular assist devices (LVADs), reducing hospitalizations, and improving quality of life and outcomes in advanced HF. Recent studies have highlighted how metabolic and endocrine dysfunction may be a consequence of, or associated with, HF, and may represent a novel (still neglected) therapeutic target in the treatment of HF. On the other hand, it is not clear whether LVAD support, may impact the outcome by also improving organ perfusion as well as improving the neuro-hormonal state of the patients, reducing the endocrine dysfunction. Moreover, endocrine function is likely a major determinant of human homeostasis, and is a key issue in the recovery from critical illness. Care of the endocrine function may contribute to improving cardiac contractility, immune function, as well as infection control, and rehabilitation during and after a LVAD placement. In this review, data on endocrine challenges in patients carrying an LVAD are gathered to highlight pathophysiological states relevant to this setting of patients, and to summarize the current therapeutic suggestions in the treatment of thyroid dysfunction, and vitamin D, erythropoietin and testosterone administration.
    MeSH term(s) Cardiac Rehabilitation/instrumentation ; Endocrine System Diseases/etiology ; Endocrine System Diseases/therapy ; Erythropoietin/administration & dosage ; Heart Failure/complications ; Heart Failure/rehabilitation ; Heart-Assist Devices ; Humans ; Testosterone/administration & dosage ; Thyroid Diseases/etiology ; Thyroid Diseases/therapy ; Vitamin D/administration & dosage
    Chemical Substances Erythropoietin (11096-26-7) ; Vitamin D (1406-16-2) ; Testosterone (3XMK78S47O)
    Language English
    Publishing date 2021-03-05
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu13030861
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Risk factors for surgical site infection following cardiac surgery in a region endemic for multidrug resistant organisms.

    Conoscenti, Elena / Enea, Giuseppe / Deschepper, Mieke / Huis In 't Veld, Diana / Campanella, Maria / Raffa, Giuseppe / Arena, Giuseppe / Morsolini, Marco / Alduino, Rossella / Tuzzolino, Fabio / Panarello, Giovanna / Mularoni, Alessandra / Martucci, Gennaro / Mattina, Alessandro / Blot, Stijn

    Intensive & critical care nursing

    2023  Volume 81, Page(s) 103612

    Abstract: Objectives: To identify risk factors for surgical site infections following cardiosurgery in an area endemic for multidrug resistant organisms.: Design: Single-center, historical cohort study including patients who underwent cardiosurgery during a 6- ... ...

    Abstract Objectives: To identify risk factors for surgical site infections following cardiosurgery in an area endemic for multidrug resistant organisms.
    Design: Single-center, historical cohort study including patients who underwent cardiosurgery during a 6-year period (2014-2020).
    Setting: Joint Commission International accredited, multiorgan transplant center in Palermo, Italy.
    Main outcome measures: Surgical site infection was the main outcome.
    Results: On a total of 3609 cardiosurgery patients, 184 developed surgical site infection (5.1 %). Intestinal colonization with multidrug resistant organisms was more frequent in patients with surgical site infections (69.6 % vs. 33.3 %; p < 0.001). About half of surgical site infections were caused by Gram-negative bacteria (n = 97; 52.7 %). Fifty surgical site infections were caused by multidrug resistant organisms (27.1 %), with extended-spectrum Beta-lactamase-producing Enterobacterales (n = 16; 8.7 %) and carbapenem-resistant Enterobacterales (n = 26; 14.1 %) being the predominant resistance problem. However, in only 24 of surgical site infections caused by multidrug resistant organisms (48 %), mostly carbapenem-resistant Enterobacterales (n = 22), a pathogen match between the rectal surveillance culture and surgical site infections clinical culture was demonstrated. Nevertheless, multivariate logistic regression analysis identified a rectal swab culture positive for multidrug resistant organisms as an independent risk factor for SSI (odds ratio 3.95, 95 % confidence interval 2.79-5.60). Other independent risk factors were female sex, chronic dialysis, diabetes mellitus, previous cardiosurgery, previous myocardial infarction, being overweight/obese, and longer intubation time.
    Conclusion: In an area endemic for carbapenem-resistant Enterobacterales, intestinal colonization with multidrug resistant organisms was recognized as independent risk factor for surgical site infections.
    Implications for clinical practice: No causal relationship between colonization with resistant pathogens and subsequent infection could be demonstrated. However, from a broader epidemiological perspective, having a positive multidrug resistant organisms colonization status appeared a risk factor for surgical site infections. Therefore, strict infection control measures to prevent cross-transmission remain pivotal (e.g., nasal decolonization, hand hygiene, and skin antisepsis).
    MeSH term(s) Humans ; Female ; Male ; Surgical Wound Infection/epidemiology ; Surgical Wound Infection/etiology ; Surgical Wound Infection/drug therapy ; Cross Infection/epidemiology ; Drug Resistance, Multiple, Bacterial ; Cohort Studies ; Risk Factors ; Cardiac Surgical Procedures/adverse effects ; Carbapenems ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use
    Chemical Substances Carbapenems ; Anti-Bacterial Agents
    Language English
    Publishing date 2023-12-27
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1105892-4
    ISSN 1532-4036 ; 0964-3397
    ISSN (online) 1532-4036
    ISSN 0964-3397
    DOI 10.1016/j.iccn.2023.103612
    Database MEDical Literature Analysis and Retrieval System OnLINE

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