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Article ; Online: Far-field perturbations of vortex patches.

Constantin, Peter

Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

2015 Volume 373, Issue 2050

Abstract: In this paper I investigate the dynamics of vortex patches in the Yudovitch phase space. I derive an approximation for the evolution of the vorticity in the case of nested vortex patches with distant boundaries, and study its long-time behaviour. ...

Abstract	In this paper I investigate the dynamics of vortex patches in the Yudovitch phase space. I derive an approximation for the evolution of the vorticity in the case of nested vortex patches with distant boundaries, and study its long-time behaviour.
Language	English
Publishing date	2015-09-13
Publishing country	England
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	208381-4
ISSN	1471-2962 ; 0080-4614 ; 0264-3820 ; 0264-3952 ; 1364-503X
ISSN (online)	1471-2962
ISSN	0080-4614 ; 0264-3820 ; 0264-3952 ; 1364-503X
DOI	10.1098/rsta.2014.0277
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Article ; Online: Effects of tryptophan and probiotic supplementation on growth and behavior in quail.

Yıldırım, A / Kraimi, N / Constantin, P / Mercerand, F / Leterrier, C

Poultry science

2020 Volume 99, Issue 11, Page(s) 5206–5213

Abstract: In laying hens, a diet supplemented with tryptophan (Trp) has been shown to affect their pecking behavior. However, unlike this positive effect, Trp is also involved in negative effects on behavior and stress through indolic pathways. Indole production ... ...

Abstract	In laying hens, a diet supplemented with tryptophan (Trp) has been shown to affect their pecking behavior. However, unlike this positive effect, Trp is also involved in negative effects on behavior and stress through indolic pathways. Indole production can be reduced by probiotics (Pro), thus we hypothesized that Pro may prevent negative effects of Trp and increase beneficial effects on behavior in birds. Combined effects of Pro and Trp were also expected. To investigate the effects on behavior in birds of supplementing with a high level of Trp with or without Pro, Japanese quail were used because their behavior can be influenced by Pediococcus acidilactici, and they can be highly aggressive. Quails (n = 120) were assigned to 4 groups in a 2 × 2 factorial design for 55 d: C-C (control diet with usual Trp level, 0.3%; without Pro; n = 30), Trp-C (Trp: 2%; without Pro; n = 30), C-Pro (control diet; with Pro: 1 x 10
MeSH term(s)	Animal Feed/analysis ; Animals ; Behavior, Animal/drug effects ; Coturnix/growth & development ; Diet/veterinary ; Dietary Supplements ; Female ; Male ; Probiotics/pharmacology ; Tryptophan/pharmacology
Chemical Substances	Tryptophan (8DUH1N11BX)
Language	English
Publishing date	2020-08-14
Publishing country	England
Document type	Journal Article
ZDB-ID	242586-5
ISSN	1525-3171 ; 0032-5791
ISSN (online)	1525-3171
ISSN	0032-5791
DOI	10.1016/j.psj.2020.07.047
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Article ; Online: An exploratory clinical trial to evaluate the efficacy of an experimental dentifrice formulation in the relief of dentine hypersensitivity.

Parkinson, C / Constantin, P / Goyal, C / Hall, C

Journal of dentistry

2016 Volume 56, Page(s) 39–44

Abstract: Objectives: This study aimed to investigate whether addition of an octadecene/maleic anhydride copolymer (O/MA) to a potassium nitrate (KNO: Methods: This was a randomised, examiner-blind, controlled, parallel group study in 139 healthy subjects with ...

Abstract	Objectives: This study aimed to investigate whether addition of an octadecene/maleic anhydride copolymer (O/MA) to a potassium nitrate (KNO Methods: This was a randomised, examiner-blind, controlled, parallel group study in 139 healthy subjects with at ≥2 sensitive teeth. Assessment of dentine hypersensitivity to tactile (Yeaple probe) and evaporative (air) stimuli (Schiff Sensitivity Scale, visual analogue scale [VAS]) was carried out at baseline and after 1, 2, 4 and 8 weeks twice daily treatment with an experimental 5% KNO Results: Across the treatment period an improvement in sensitivity to evaporative air stimulus was observed for all products and to a tactile stimulus for the potassium-containing treatments, with the greatest reductions for the experimental dentifrice (5% KNO Conclusion: This study provides initial clinical evidence to suggest that addition of a polymer excipient may enhance the anti-sensitivity efficacy of potassium-containing dentifrices. Clinical significance: Daily use potassium-containing dentifrices are established as efficacious for the relief of dentine hypersensitivity. Inclusion of a polymer excipient in such formulations may facilitate delivery of potassium to the dentine surface and so enhance clinical efficacy. Further clinical studies are required to confirm this hypothesis.
MeSH term(s)	Adolescent ; Adult ; Aged ; Dentifrices/administration & dosage ; Dentifrices/chemistry ; Dentifrices/therapeutic use ; Dentin Desensitizing Agents/administration & dosage ; Dentin Desensitizing Agents/chemistry ; Dentin Desensitizing Agents/therapeutic use ; Dentin Sensitivity/drug therapy ; Female ; Fluorides/therapeutic use ; Humans ; Male ; Maleic Anhydrides ; Middle Aged ; Nitrates ; Oleic Acids/chemistry ; Oleic Acids/therapeutic use ; Pain Measurement ; Phosphates ; Potassium Compounds/therapeutic use ; Sodium Fluoride/therapeutic use ; Touch ; Treatment Outcome ; Young Adult
Chemical Substances	Dentifrices ; Dentin Desensitizing Agents ; Maleic Anhydrides ; Nitrates ; Oleic Acids ; Phosphates ; Potassium Compounds ; fluorophosphate (15181-43-8) ; Sodium Fluoride (8ZYQ1474W7) ; Fluorides (Q80VPU408O) ; potassium nitrate (RU45X2JN0Z)
Language	English
Publishing date	2016-10-21
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	186068-9
ISSN	1879-176X ; 0300-5712
ISSN (online)	1879-176X
ISSN	0300-5712
DOI	10.1016/j.jdent.2016.10.013
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Article ; Online: Columnar Liquid Crystals of Copper(I) Complexes with Ionic Conductivity and Solid State Emission.

Cîrcu, Viorel / Ganea, Constantin P / Secu, Mihail / Manaila-Maximean, Doina / Marinescu, George Cătălin / Popescu, Roua Gabriela / Pasuk, Iuliana

Molecules (Basel, Switzerland)

2023 Volume 28, Issue 10

Abstract: Two neutral copper(I) halide complexes ([Cu(BTU) ...

Abstract	Two neutral copper(I) halide complexes ([Cu(BTU)
Language	English
Publishing date	2023-05-19
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	1413402-0
ISSN	1420-3049 ; 1431-5165 ; 1420-3049
ISSN (online)	1420-3049
ISSN	1431-5165 ; 1420-3049
DOI	10.3390/molecules28104196
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Article ; Online: A NEW LOOK AT THE LYAPUNOV INEQUALITY

Constantin P. Niculescu

Mathematics and its Applications : Annals of the Academy of Romanian Scientists, Vol 3, Iss 1, Pp 207-

2011 Volume 217

Abstract: Given a Banach space E, it is proved that any function u in C2([a; b];E) verifies a Lyapunov inequality. The provided constant is sharp. Several applications are included. ...

Abstract	Given a Banach space E, it is proved that any function u in C2([a; b];E) verifies a Lyapunov inequality. The provided constant is sharp. Several applications are included.
Keywords	Sturm-Liouville problem ; function of bounded variation ; differentiable function ; Mathematics ; QA1-939 ; Science ; Q ; DOAJ:Mathematics ; DOAJ:Mathematics and Statistics
Language	English
Publishing date	2011-07-01T00:00:00Z
Publisher	Academy of Romanian Scientists Publishing House
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: The elusive singularity.

Constantin, P

Proceedings of the National Academy of Sciences of the United States of America

1997 Volume 94, Issue 24, Page(s) 12761

Language	English
Publishing date	1997-11-25
Publishing country	United States
Document type	Comment ; Journal Article
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.94.24.12761
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Article: Effects of tryptophan and probiotic supplementation on growth and behavior in quail

Yıldırım, A / Kraimi, N / Constantin, P / Mercerand, F / Leterrier, C

Poultry science. 2020 Nov., v. 99, no. 11

2020

Abstract	In laying hens, a diet supplemented with tryptophan (Trp) has been shown to affect their pecking behavior. However, unlike this positive effect, Trp is also involved in negative effects on behavior and stress through indolic pathways. Indole production can be reduced by probiotics (Pro), thus we hypothesized that Pro may prevent negative effects of Trp and increase beneficial effects on behavior in birds. Combined effects of Pro and Trp were also expected. To investigate the effects on behavior in birds of supplementing with a high level of Trp with or without Pro, Japanese quail were used because their behavior can be influenced by Pediococcus acidilactici, and they can be highly aggressive. Quails (n = 120) were assigned to 4 groups in a 2 × 2 factorial design for 55 d: C-C (control diet with usual Trp level, 0.3%; without Pro; n = 30), Trp-C (Trp: 2%; without Pro; n = 30), C-Pro (control diet; with Pro: 1 x 10⁹ CFU/L P. acidilactici in drinking water; n = 30), and Trp-Pro (Trp 2%; with Pro; n = 30). Body weight was measured every week, and different tests were conducted to investigate behavioral characteristics of each quail. Contrary to our hypothesis, there was almost no interaction between Trp and Pro treatments. Tryptophan supplementation significantly (P < 0.05) reduced live weight up to 27 d, whereas Pro treatment had no effect. There was no significant difference between groups for tonic immobility variables (P > 0.05). The birds fed the high Trp diet spent significantly less time in the periphery of the open field than those fed the control diet and moved less in the arena during the social isolation test. Interindividual distances were significantly lower in males fed with Trp 2% than with the control diet, whereas Trp and Pro supplements interacted in females. The treatments did not affect sexual motivation in males. These results indicate that a high level of Trp reduced growth and appeared to enhance emotional reactivity in quails and that supplementing with Pro did not reduce these effects. In conclusion, feeding high Trp for 55 d cannot be recommended as a strategy to improve social behavior unlike effects observed in laying hens.
Keywords	Coturnix japonica ; Pediococcus acidilactici ; body weight ; diet ; drinking water ; indoles ; laying hens ; males ; motivation ; pecking ; probiotics ; quails ; social behavior ; tonic immobility ; tryptophan
Language	English
Dates of publication	2020-11
Size	p. 5206-5213.
Publishing place	Elsevier Inc.
Document type	Article
ZDB-ID	242586-5
ISSN	1525-3171 ; 0032-5791
ISSN (online)	1525-3171
ISSN	0032-5791
DOI	10.1016/j.psj.2020.07.047
Database	NAL-Catalogue (AGRICOLA)

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Book ; Online: Comparison between the HUBCAP and DIGITBrain Platforms for Model-Based Design and Evaluation of Digital Twins

Talasila, Prasad / Crăciunean, Daniel-Cristian / Bogdan-Constantin, Pirvu / Larsen, Peter Gorm / Zamfirescu, Constantin / Scovill, Alea

2022

Abstract: Digital twin technology is an essential approach to managing the lifecycle of industrial products. Among the many approaches used to manage digital twins, co-simulation has proven to be a reliable one. There have been multiple attempts to create ... ...

Abstract	Digital twin technology is an essential approach to managing the lifecycle of industrial products. Among the many approaches used to manage digital twins, co-simulation has proven to be a reliable one. There have been multiple attempts to create collaborative and sustainable platforms for management of digital twins. This paper compares two such platforms, namely the HUBCAP and the DIGITbrain. Both these platforms have been and continue to be used among a stable group of researchers and industrial product manufacturers of digital twin technologies. This comparison of the HUBCAP and the DIGITbrain platforms is illustrated with an example use case of industrial factory to be used for manufacturing of agricultural robots.
Keywords	Computer Science - Computers and Society ; Computer Science - Distributed ; Parallel ; and Cluster Computing
Publishing date	2022-12-15
Publishing country	us
Document type	Book ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article: Two- and three-dimensional magnetic reconnection observed in the Eulerian-Lagrangian analysis of magnetohydrodynamics equations.

Ohkitani, K / Constantin, P

Physical review. E, Statistical, nonlinear, and soft matter physics

2008 Volume 78, Issue 6 Pt 2, Page(s) 66315

Abstract: We study reconnection phenomena in magnetohydrodynamics on the basis of a magnetohydrodynamic version of the Eulerian-Lagrangian analysis. We find that the methods are useful in capturing time scales associated with magnetic reconnection both in two and ... ...

Abstract	We study reconnection phenomena in magnetohydrodynamics on the basis of a magnetohydrodynamic version of the Eulerian-Lagrangian analysis. We find that the methods are useful in capturing time scales associated with magnetic reconnection both in two and three dimensions. Visualizations show that the determinants of the Jacobian determinants of the diffusive labels are small where active reconnection takes place. The resetting of the diffusive labels extracts a short time scale during reconnection.
Language	English
Publishing date	2008-12
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ISSN	1539-3755
ISSN	1539-3755
DOI	10.1103/PhysRevE.78.066315
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Article: Efficacy of an experimental 3% potassium nitrate mouthwash in providing long-term relief from dentin hypersensitivity: An 8-week randomized controlled study (Study 2).

Hall, Claire / Sufi, Farzana / Constantin, Paul

American journal of dentistry

2017 Volume 30, Issue 6, Page(s) 335–342

Abstract: Purpose: To evaluate the efficacy of an experimental mouthwash containing 3% potassium nitrate (KNO3) in the relief of dentin hypersensitivity when used as an adjunct to brushing with fluoride toothpaste compared with the use of the same toothpaste ... ...

Abstract	Purpose: To evaluate the efficacy of an experimental mouthwash containing 3% potassium nitrate (KNO3) in the relief of dentin hypersensitivity when used as an adjunct to brushing with fluoride toothpaste compared with the use of the same toothpaste alone. Methods: This was a randomized, two-treatment, examiner-blind, parallel-design single-center, 8-week study in healthy subjects with self-reported and clinically diagnosed dentin hypersensitivity. Subjects were randomized to receive either fluoride toothpaste plus 3.0% KNO₂ mouthwash or the same fluoride toothpaste alone, and instructed to use their allocated treatment twice daily for the next 8 weeks. Dentin hypersensitivity was evaluated at baseline and following 4 and 8 weeks of treatment through assessment of responses to evaporative (air) and tactile stimuli [measured by the Schiff sensitivity scale/a visual rating scale (VRS) and tactile threshold, respectively], and using the Dentin Hypersensitivity Experience Questionnaire (DHEQ, a validated quality-of-life instrument for dentin hyper-sensitivity). Results: A total of 135 subjects were randomized and all completed the study. Both treatment groups demonstrated statistically significant improvements in sensitivity from baseline for each clinical measure of sensitivity (P< 0.0001) at Week 4 and Week 8. The toothpaste plus mouthwash group showed greater reductions in sensitivity at both timepoints for all clinical measures; between-treatment differences were only statistically significant for responses to an evaporative (air) stimulus (Schiff sensitivity score and VRS) at Week 4. There was evidence of an improvement in dentin hypersensitivity-associated quality of life as measured by changes from baseline in several DHEQ parameters for both treatment groups, but there were no statistically significant differences between treatments. Clinical significance: Although in the current study adjunctive use of a 3% KNO₂ mouthwash did not provide statistically significant improvements in dentin hypersensitivity for all clinical measures at all timepoints compared with use of fluoride toothpaste alone, the reductions in sensitivity observed in this study are compatible with the findings of a previous study that showed adjunctive use of a 3% KNO₂ mouthwash to be effective in providing relief from dentin hypersensitivity after 8 weeks' twice-daily use.
MeSH term(s)	Arginine ; Calcium Carbonate ; Dentin Desensitizing Agents ; Dentin Sensitivity/therapy ; Double-Blind Method ; Fluorides ; Humans ; Mouthwashes/therapeutic use ; Nitrates/therapeutic use ; Potassium Compounds/therapeutic use ; Quality of Life ; Sodium Fluoride ; Toothpastes ; Treatment Outcome
Chemical Substances	Dentin Desensitizing Agents ; Mouthwashes ; Nitrates ; Potassium Compounds ; Toothpastes ; Sodium Fluoride (8ZYQ1474W7) ; Arginine (94ZLA3W45F) ; Calcium Carbonate (H0G9379FGK) ; Fluorides (Q80VPU408O) ; potassium nitrate (RU45X2JN0Z)
Language	English
Publishing date	2017-12
Publishing country	United States
Document type	Clinical Trial ; Randomized Controlled Trial
ZDB-ID	645142-1
ISSN	0894-8275
ISSN	0894-8275
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