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  1. Article: A new multidimensional group intervention for cognitive and psychosocial functioning for older adults: Background, content, and process evaluation.

    Chadjikyprianou, Andreas / Constantinidou, Fofi

    Frontiers in medicine

    2023  Volume 10, Page(s) 1161060

    Abstract: Introduction: An essential element of quality aging is the maintenance of cognitive and psychosocial functioning. The principal objective of the present paper was to present the theoretical framework, content and process evaluation of a newly developed ... ...

    Abstract Introduction: An essential element of quality aging is the maintenance of cognitive and psychosocial functioning. The principal objective of the present paper was to present the theoretical framework, content and process evaluation of a newly developed multi-dimensional group intervention designed to strengthen/improve areas of cognitive and psychosocial functioning in adults over 65.
    Methods: The intervention implements multiple methodologies aiming to facilitate contextual integration of learned concepts and strategies derived from clinical psychology and rehabilitation. It moves seamlessly on the cognition-emotion axes and consists of five active ingredients selected to address challenges associated with aging: Memory Compensatory Strategies, Problem-Solving, Emotion Regulation, Mindfulness, and Locus of Control. Thirty participants joined the intervention group aged 65-75  years (
    Results: Results from the Participant Satisfaction Scale indicate that the program was perceived very positively by participants, who also reported implementing their newly learned strategies in activities of daily life. Furthermore, there was high correlation between internal locus of control and the learned strategies.
    Discussion: The outcomes of this analysis indicate that the intervention is feasible and well tolerated by our target group. This multidimensional intervention may offer a valuable contribution to public health care and dementia prevention for older adults.
    Clinical trial registration: [https://clinicaltrials.gov/ct2/results?cond=NCT01481246], identifier [NCT01481246].
    Language English
    Publishing date 2023-04-20
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1161060
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Effects of Systematic Categorization Training on Cognitive Performance in Healthy Older Adults and in Adults with Traumatic Brain Injury.

    Constantinidou, Fofi

    Behavioural neurology

    2019  Volume 2019, Page(s) 9785319

    Abstract: This study investigated the effects of hierarchical cognitive training using the categorization program (CP), designed initially for adults with cognitive deficits associated with traumatic brain injury (TBI). Fifty-eight participants were included: a ... ...

    Abstract This study investigated the effects of hierarchical cognitive training using the categorization program (CP), designed initially for adults with cognitive deficits associated with traumatic brain injury (TBI). Fifty-eight participants were included: a group of fifteen young adults with TBI (ages 18-48), another group of fifteen noninjured young adults (ages 18-50), and two groups of adults over 60 randomly assigned into the experimental group (
    MeSH term(s) Adult ; Aged ; Brain Injuries, Traumatic/complications ; Brain Injuries, Traumatic/therapy ; Cognition/physiology ; Cognition Disorders/complications ; Cognition Disorders/rehabilitation ; Cognition Disorders/therapy ; Cognitive Behavioral Therapy/methods ; Concept Formation/physiology ; Decision Making/physiology ; Female ; Humans ; Learning/physiology ; Male ; Middle Aged ; Neuropsychological Tests
    Language English
    Publishing date 2019-07-29
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 1001896-7
    ISSN 1875-8584 ; 0953-4180
    ISSN (online) 1875-8584
    ISSN 0953-4180
    DOI 10.1155/2019/9785319
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: The cortical and subcortical substrates of quality of life through substrates of self-awareness and executive functions, in chronic moderate-to-severe TBI.

    Pettemeridou, Eva / Constantinidou, Fofi

    Brain injury

    2022  Volume 36, Issue 1, Page(s) 110–120

    Abstract: Background: Moderate-to-severe traumatic brain injury (TBI) follows a chronic neuro-psychological sequelae, interfering with quality of life (QOL).: Objective: To investigate the chronic effects of moderate-to-severe TBI as expressed by greater ... ...

    Abstract Background: Moderate-to-severe traumatic brain injury (TBI) follows a chronic neuro-psychological sequelae, interfering with quality of life (QOL).
    Objective: To investigate the chronic effects of moderate-to-severe TBI as expressed by greater atrophy in specific regions-of-interest relating to executive functions (EF) and self-awareness (SA); and whether this atrophy reflects on EF, SA deficits and QOL.
    Methods: Thirty-one males with chronic moderate-to-severe TBI, aged 18-51, were compared to 24 non-injured males (age range = 21-49), matched on age and education. EF was assessed through a composite score. SA and QOL were assessed using generic and TBI-specific measures. Online masks were applied on magnetic resonance images to extract EF and SA - related regions-of-interest.
    Results: Findings revealed that participants with TBI presented with less volume in fronto-temporal cortical and subcortical regions, than controls. An interrelation between EF and SA - related regions was revealed. Participants with TBI scored lower on neuropsychosocial measures, than controls. Differences in EF and SA were reflected on the related regions-of-interest. Satisfaction with QOL was predicted by these regions-of-interest.
    Conclusion: Chronic TBI effects on brain volume extend on EF, SA, and QOL; highlighting the role of SA between EF and QOL, and the need for personalized interventions in improving recovery outcome.
    MeSH term(s) Adult ; Atrophy ; Brain Injuries, Traumatic/diagnostic imaging ; Brain Injuries, Traumatic/psychology ; Brain Injury, Chronic ; Executive Function ; Humans ; Male ; Middle Aged ; Quality of Life ; Young Adult
    Language English
    Publishing date 2022-03-05
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 639115-1
    ISSN 1362-301X ; 0269-9052
    ISSN (online) 1362-301X
    ISSN 0269-9052
    DOI 10.1080/02699052.2022.2034960
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Long-term psychological impact of the pandemic COVID-19: Identification of high-risk groups and assessment of precautionary measures five months after the first wave of restrictions was lifted.

    Solomou, Ioulia / Nikolaou, Flora / Michaelides, Michalis P / Constantinidou, Fofi

    PLOS global public health

    2024  Volume 4, Issue 2, Page(s) e0002847

    Abstract: Critical facets of our lives have been disrupted by the COVID-19 outbreak for almost three years. During this time, there has been a lot of clinical and research interest in issues related to mental health. However, few have examined the pandemic's long- ... ...

    Abstract Critical facets of our lives have been disrupted by the COVID-19 outbreak for almost three years. During this time, there has been a lot of clinical and research interest in issues related to mental health. However, few have examined the pandemic's long-term psychological effects. The aims of the present study were to assess the long-term psychological impact of the pandemic COVID -19, five months after the first wave restriction measures were lifted, to identify high-risk groups and to address the use of precautionary measures (PM). Information about sociodemographic characteristics, mental health, coping mechanisms, and compliance with precautionary measures (PM) were all gathered in Cyprus through an anonymous online survey. The poll was completed by 1128 people (73% of whom were female). For the purposes of the present study, descriptive statistics and structural equation modeling were used. 32.3% of participants experienced moderate-to-severe anxiety symptoms, where 16.4% and 23% reported moderate-to-severe depression and post-traumatic stress symptoms respectively. Lower levels of anxiety, depression, and post-traumatic stress symptoms as well as greater compliance to PM were linked to higher levels of resilience. Additionally, subgroups of participants, at a higher risk for negative psychological effects were identified, such as women and young adults. Our findings demonstrate the long-lasting effects of the COVID-19 pandemic on mental health and provide guidance on how to deal with similar situations. It also raises questions about the concurrent effects on people with the long COVID syndrome.
    Language English
    Publishing date 2024-02-23
    Publishing country United States
    Document type Journal Article
    ISSN 2767-3375
    ISSN (online) 2767-3375
    DOI 10.1371/journal.pgph.0002847
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: The Association Between Brain Reserve, Cognitive Reserve, and Neuropsychological and Functional Outcomes in Males With Chronic Moderate-to-Severe Traumatic Brain Injury.

    Pettemeridou, Eva / Constantinidou, Fofi

    American journal of speech-language pathology

    2021  Volume 30, Issue 2S, Page(s) 883–893

    Abstract: Purpose Moderate-to-severe traumatic brain injury (TBI) leads to significant neural and cognitive impairment, affecting functional outcome. This study investigated the chronic effects of moderate-to-severe TBI on brain reserve (BR), cognitive reserve (CR) ...

    Abstract Purpose Moderate-to-severe traumatic brain injury (TBI) leads to significant neural and cognitive impairment, affecting functional outcome. This study investigated the chronic effects of moderate-to-severe TBI on brain reserve (BR), cognitive reserve (CR), and neuropsychological and functional outcome. Method The group with TBI consisted of 41 male participants with a primary diagnosis of moderate-to-severe closed head injury (time since injury [TSI],
    MeSH term(s) Brain/diagnostic imaging ; Brain Injuries, Traumatic/complications ; Brain Injuries, Traumatic/diagnosis ; Brain Injury, Chronic ; Cognitive Reserve ; Executive Function ; Humans ; Magnetic Resonance Imaging ; Male ; Neuropsychological Tests
    Language English
    Publishing date 2021-02-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1154406-5
    ISSN 1558-9110 ; 1058-0360
    ISSN (online) 1558-9110
    ISSN 1058-0360
    DOI 10.1044/2020_AJSLP-20-00053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Prevalence and Predictors of Anxiety and Depression Symptoms during the COVID-19 Pandemic and Compliance with Precautionary Measures: Age and Sex Matter.

    Solomou, Ioulia / Constantinidou, Fofi

    International journal of environmental research and public health

    2020  Volume 17, Issue 14

    Abstract: Effective management of the global pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (also known as COVID-19), resulted in the implementation of severe restrictions in movement and enforcement of social distancing measures. This study ... ...

    Abstract Effective management of the global pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (also known as COVID-19), resulted in the implementation of severe restrictions in movement and enforcement of social distancing measures. This study aimed to understand and characterize the psychosocial effects of the COVID-19 pandemic in the general population and to identify risks and protective factors that predict changes in mental health status. In addition, the study investigated compliance with precautionary measures (PM) to halt the spread of the virus. The online anonymous survey collected information on sociodemographic data, compliance with PM, quality of life (QOL), and mental health via the Generalized Anxiety Disorder-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9). A total of 1642 adult participants (71.6% women, 28.4% men) completed the survey in the European island country, Cyprus. A large percentage (48%) reported significant financial concerns and 66.7% significant changes in their QOL. About 41% reported symptoms associated with mild anxiety; 23.1% reported moderate-severe anxiety symptoms. Concerning depression, 48% reported mild and 9.2% moderate-severe depression symptoms. Women, younger age (18-29), student status, unemployment status, prior psychiatric history, and those reporting greater negative impact on their QOL, were at higher risk for increased anxiety and depression symptoms (
    MeSH term(s) Adolescent ; Adult ; Anxiety/epidemiology ; Betacoronavirus ; COVID-19 ; Coronavirus Infections/epidemiology ; Coronavirus Infections/prevention & control ; Coronavirus Infections/psychology ; Cyprus/epidemiology ; Depression/epidemiology ; Female ; Humans ; Male ; Mental Health ; Middle Aged ; Pandemics/prevention & control ; Patient Compliance ; Pneumonia, Viral/epidemiology ; Pneumonia, Viral/prevention & control ; Pneumonia, Viral/psychology ; Prevalence ; Quality of Life ; SARS-CoV-2 ; Surveys and Questionnaires ; Universal Precautions/statistics & numerical data ; Young Adult
    Keywords covid19
    Language English
    Publishing date 2020-07-08
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph17144924
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  7. Article: The Neurocognitive Study for the Aging: Longitudinal Analysis on the Contribution of Sex, Age, Education and

    Chadjikyprianou, Andreas / Hadjivassiliou, Marilena / Papacostas, Savvas / Constantinidou, Fofi

    Frontiers in genetics

    2021  Volume 12, Page(s) 680531

    Abstract: Objective: ...

    Abstract Objective:
    Language English
    Publishing date 2021-07-13
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2606823-0
    ISSN 1664-8021
    ISSN 1664-8021
    DOI 10.3389/fgene.2021.680531
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  8. Article: Regional Brain Volume, Brain Reserve and MMSE Performance in Healthy Aging From the NEUROAGE Cohort: Contributions of Sex, Education, and Depression Symptoms.

    Pettemeridou, Eva / Kallousia, Eleni / Constantinidou, Fofi

    Frontiers in aging neuroscience

    2021  Volume 13, Page(s) 711301

    Abstract: ... ...

    Abstract Objective
    Language English
    Publishing date 2021-11-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2558898-9
    ISSN 1663-4365
    ISSN 1663-4365
    DOI 10.3389/fnagi.2021.711301
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  9. Article ; Online: Strategies to Manage the Thinking and Emotional Difficulties of Long COVID: A Guide for Patients and Families.

    Constantinidou, Fofi / Sander, Angelle / Bergquist, Thomas / Zimmerman, Amanda Sacks / Kingsley, Kristine

    Archives of physical medicine and rehabilitation

    2023  

    Language English
    Publishing date 2023-10-31
    Publishing country United States
    Document type Practice Guideline
    ZDB-ID 80057-0
    ISSN 1532-821X ; 0003-9993
    ISSN (online) 1532-821X
    ISSN 0003-9993
    DOI 10.1016/j.apmr.2023.09.014
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  10. Article: Prevalence and Predictors of Anxiety and Depression Symptoms during the COVID-19 Pandemic and Compliance with Precautionary Measures: Age and Sex Matter

    Solomou, Ioulia / Constantinidou, Fofi

    Int. j. environ. res. public health (Online)

    Abstract: Effective management of the global pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (also known as COVID-19), resulted in the implementation of severe restrictions in movement and enforcement of social distancing measures. This study ... ...

    Abstract Effective management of the global pandemic caused by Severe Acute Respiratory Syndrome Coronavirus 2 (also known as COVID-19), resulted in the implementation of severe restrictions in movement and enforcement of social distancing measures. This study aimed to understand and characterize the psychosocial effects of the COVID-19 pandemic in the general population and to identify risks and protective factors that predict changes in mental health status. In addition, the study investigated compliance with precautionary measures (PM) to halt the spread of the virus. The online anonymous survey collected information on sociodemographic data, compliance with PM, quality of life (QOL), and mental health via the Generalized Anxiety Disorder-7 (GAD-7) and Patient Health Questionnaire-9 (PHQ-9). A total of 1642 adult participants (71.6% women, 28.4% men) completed the survey in the European island country, Cyprus. A large percentage (48%) reported significant financial concerns and 66.7% significant changes in their QOL. About 41% reported symptoms associated with mild anxiety; 23.1% reported moderate-severe anxiety symptoms. Concerning depression, 48% reported mild and 9.2% moderate-severe depression symptoms. Women, younger age (18-29), student status, unemployment status, prior psychiatric history, and those reporting greater negative impact on their QOL, were at higher risk for increased anxiety and depression symptoms (p < 0.05). The youngest age group and males also reported lower levels of compliance with PM. Higher compliance with PM predicted lower depression scores (p < 0.001) but higher anxiety for measures related to personal hygiene. The results of this study provide important data on the effects of the COVID-19 outbreak on mental health and QOL and identify a variety of personal and social determinants that serve as risks and protective factors. Furthermore, it has implications for policy makers demonstrating the need for effective mental health programs and guidance for the implementation of PM as a public health strategy.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #639975
    Database COVID19

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