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  1. Article ; Online: Evaluation of adherence to antipsychotics: A real-world data study using four different dosing assumptions.

    Fuente-Moreno, Marina / Dima, Alexandra L / Rubio-Valera, Maria / Baladon, Luisa / Chavarria, Victor / Contaldo, Salvatore Fabrizio / Peña-Salazar, Carlos / Serra-Sutton, Vicky / Hermida-González, Patricia / de Loño, Jorge Peláez / Rey-Abella, Maria Eugènia / Aznar-Lou, Ignacio / Serrano-Blanco, Antoni

    British journal of clinical pharmacology

    2024  

    Abstract: Aims: This study aimed to assess the frequency of dosing inconsistencies in prescription data and the effect of four dosing assumption strategies on adherence estimates for antipsychotic treatment.: Methods: A retrospective cohort, which linked ... ...

    Abstract Aims: This study aimed to assess the frequency of dosing inconsistencies in prescription data and the effect of four dosing assumption strategies on adherence estimates for antipsychotic treatment.
    Methods: A retrospective cohort, which linked prescription and dispensing data of adult patients with ≥1 antipsychotic prescription between 2015-2016 and followed up until 2019, in Catalonia (Spain). Four strategies were proposed for selecting the recommended dosing in overlapping prescription periods for the same patient and antipsychotic drug: (i) the minimum dosing prescribed; (ii) the dose corresponding to the latest prescription issued; (iii) the highest dosing prescribed; and (iv) all doses included in the overlapped period. For each strategy, one treatment episode per patient was selected, and the Continuous Medication Availability measure was used to assess adherence. Descriptive statistics were used to describe results by strategy.
    Results: Of the 277 324 prescriptions included, 76% overlapped with other prescriptions (40% with different recommended dosing instructions). The number and characteristics of patients and treatment episodes (18 292, 18 303, 18 339 and 18 536, respectively per strategy) were similar across strategies. Mean adherence was similar between strategies, ranging from 57 to 60%. However, the proportion of patients with adherence ≥90% was lower when selecting all doses (28%) compared with the other strategies (35%).
    Conclusion: Despite the high prevalence of overlapping prescriptions, the strategies proposed did not show a major effect on the adherence estimates for antipsychotic treatment. Taking into consideration the particularities of antipsychotic prescription practices, selecting the highest dose in the overlapped period seemed to provide a more accurate adherence estimate.
    Language English
    Publishing date 2024-03-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 188974-6
    ISSN 1365-2125 ; 0306-5251 ; 0264-3774
    ISSN (online) 1365-2125
    ISSN 0306-5251 ; 0264-3774
    DOI 10.1111/bcp.16042
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Assessment of the efficacy of a Crisis Intervention Team (CIT): experience in the Esplugues Mental Health Center (Barcelona).

    Martin-Iñigo, Laia / Ortiz, Sonia / Urbano, David / Teba Pérez, Silvia / Contaldo, Salvatore Fabrizio / Alvarós, Joan / Baladon, Luisa / Parody-Rúa, Elizabeth / Rubio-Valera, Maria

    Social psychiatry and psychiatric epidemiology

    2022  Volume 57, Issue 10, Page(s) 2109–2117

    Abstract: Aim: Crisis Resolution Teams (CRT) have shown positive clinical and service-use results in various countries but evidence in the south of Europe is scarce. The aim is to assess the impact of the Crisis Intervention Team (CIT) in Spain with respect to ... ...

    Abstract Aim: Crisis Resolution Teams (CRT) have shown positive clinical and service-use results in various countries but evidence in the south of Europe is scarce. The aim is to assess the impact of the Crisis Intervention Team (CIT) in Spain with respect to the course of symptomatology and mental health services use in patients served.
    Methods: Prospective observational cohort study. Assessment of the psychopathological severity (HoNOS scale) of the clinical course (CGI scale) and use of medical services.
    Results: A positive clinical course was observed following the intervention. The mean difference in HoNOS (Health of the Nation Outcome Scales) scores between baseline and discharge was 7 points (p < 0.05). On discharge, more than 60% of patients had improved their symptomatology according to the CGI scale (Clinical Global Impression) and most were discharged due to improvement or goal achievement. A tendency to reduction in the number of admissions to acute units and day hospital was observed, along with fewer emergency room visits. In contrast, an increase in the number of admissions to subacute units was seen. During the intervention, the median number of visits to the center was 15 and the median duration of care provision by the CIT was 39 days.
    Conclusions: The CIT intervention promotes patients' clinical improvement and has a positive impact in terms of reducing acute hospitalizations and emergency room visits.
    MeSH term(s) Humans ; Crisis Intervention/methods ; Mental Disorders/diagnosis ; Mental Disorders/therapy ; Mental Health ; Prospective Studies
    Language English
    Publishing date 2022-03-04
    Publishing country Germany
    Document type Journal Article ; Observational Study
    ZDB-ID 623071-4
    ISSN 1433-9285 ; 0037-7813 ; 0933-7954
    ISSN (online) 1433-9285
    ISSN 0037-7813 ; 0933-7954
    DOI 10.1007/s00127-022-02250-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Assessment of a Primary Support Program: family physicians and mental health professionals' perspective.

    Gil-Girbau, Montserrat / Peñarrubia-Maria, Maria-Teresa / Carbonell-Simeón, Davinia / Rodríguez-Ferraz, Brenda / Contaldo, Salvatore-Fabrizio / Iglesias-González, Maria / Fernández-Vergel, Rita / Blanco-García, Elena / Baladon-Higuera, Luisa / Serrano-Blanco, Antoni / Rubio-Valera, Maria

    Family practice

    2022  Volume 39, Issue 5, Page(s) 920–931

    Abstract: Background: Mental health (MH) disorders are increasingly prevalent in primary care (PC) and this has generated, in recent years, the development of strategies based on the collaborative model and the stepped care model. The Primary Support Program (PSP) ...

    Abstract Background: Mental health (MH) disorders are increasingly prevalent in primary care (PC) and this has generated, in recent years, the development of strategies based on the collaborative model and the stepped care model. The Primary Support Program (PSP) was implemented in the community of Catalonia (Spain) during 2006 to improve, from the first level of care, treatment of the population with mild-moderate complexity MH problems along with identification and referral of severe cases to specialized care. The aim of the present study was to identify the strengths and limitations of the PSP from the perspective of health professionals involved in the programme.
    Methods: An explanatory qualitative study based on Grounded Theory. We conducted group semistructured interviews with 37 family physicians and 34 MH professionals. A constant comparative method of analysis was performed.
    Results: Operation of the PSP is influenced by internal factors, such as the programme framework, MH liaison, management of service supply and demand, and the professional team involved. Additionally, external factors which had an impact were related to the patient, the professionals, the Health System, and community resources.
    Conclusions: The operation of the PSP could benefit from a review of the programme framework and optimization of MH liaison. Improvements are also proposed for MH training in PC, intraprofessional coordination, use of community resources, and creation of efficient continuous assessment systems.
    MeSH term(s) Health Personnel ; Humans ; Mental Health ; Mental Health Services ; Physicians, Family ; Primary Health Care
    Language English
    Publishing date 2022-02-28
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 605939-9
    ISSN 1460-2229 ; 0263-2136
    ISSN (online) 1460-2229
    ISSN 0263-2136
    DOI 10.1093/fampra/cmac013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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