Article ; Online: Latent Tuberculosis Infection Cascade of Care among Asylum Seekers in Verona, Italy.
Journal of health care for the poor and underserved
2022 Volume 33, Issue 2, Page(s) 934–949
Abstract: Our study aimed to assess latent tuberculosis infection (LTBI) prevalence, screening uptake, adherence to preventive treatment, and their predictors in a large cohort of asylum seekers. We retrospectively analysed data of migrants screened in 2015-2017 ... ...
Abstract | Our study aimed to assess latent tuberculosis infection (LTBI) prevalence, screening uptake, adherence to preventive treatment, and their predictors in a large cohort of asylum seekers. We retrospectively analysed data of migrants screened in 2015-2017 at the Migrant's Service in Verona, Italy. Sequential interferon-gamma-release-assay (IGRA) was performed to confirm only tuberculin-skin-test (TST) results ranking from 5 to 14 mm. Among 2,486 asylum seekers, screening adherence was 89.74% and LTBI prevalence was 28.8% (CI95% 27.0;30.5). Predictors of LTBI diagnosis were: male gender (OR 1.62), age 24 years or older (OR 1.47) and African origin (OR 1.78). Therapy completion rate was 69.6% and resulted associated with African origin (OR 1.75) and being older than 24 years (OR 2.89). Sequential IGRA testing, given its expensiveness, could be used to confirm only intermediate TST results, thus enabling further LTBI cases to be detected and avoiding unnecessary preventive treatments. |
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MeSH term(s) | Adult ; Humans ; Interferon-gamma Release Tests/methods ; Latent Tuberculosis/diagnosis ; Latent Tuberculosis/epidemiology ; Male ; Mass Screening ; Refugees ; Retrospective Studies ; Tuberculin Test/methods ; Young Adult |
Language | English |
Publishing date | 2022-05-27 |
Publishing country | United States |
Document type | Journal Article |
ZDB-ID | 1142637-8 |
ISSN | 1548-6869 ; 1049-2089 |
ISSN (online) | 1548-6869 |
ISSN | 1049-2089 |
DOI | 10.1353/hpu.2022.0073 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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