Article ; Online: Toward a standard model for autophagosome biogenesis.
2023 Volume 222, Issue 7
Abstract: Two papers in this issue resolve a long-standing obstacle to a "standard model" for autophagosome biogenesis in mammals. The first, Olivas et al. (2023. J. Cell Biol. https://doi.org/10.1083/jcb.202208088), uses biochemistry to confirm that the lipid ... ...
Abstract | Two papers in this issue resolve a long-standing obstacle to a "standard model" for autophagosome biogenesis in mammals. The first, Olivas et al. (2023. J. Cell Biol. https://doi.org/10.1083/jcb.202208088), uses biochemistry to confirm that the lipid scramblase ATG9A is a bona fide autophagosome component, while the second, Broadbent et al. (2023. J. Cell Biol. https://doi.org/10.1083/jcb.202210078), uses particle tracking to show that the dynamics of autophagy proteins are consistent with the concept. |
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MeSH term(s) | Animals ; Autophagosomes ; Autophagy ; Macroautophagy ; Mammals ; Autophagy-Related Proteins |
Chemical Substances | Autophagy-Related Proteins |
Language | English |
Publishing date | 2023-06-05 |
Publishing country | United States |
Document type | Journal Article ; Research Support, Non-U.S. Gov't ; Comment |
ZDB-ID | 218154-x |
ISSN | 1540-8140 ; 0021-9525 |
ISSN (online) | 1540-8140 |
ISSN | 0021-9525 |
DOI | 10.1083/jcb.202304011 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
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