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  1. Article ; Online: Use of transcriptomics for diagnosis of infections and sepsis in children: A narrative review.

    Casini, Francesca / Valentino, Maria Sole / Lorenzo, Marc Garcia / Caiazzo, Roberta / Coppola, Crescenzo / David, Daniela / Di Tonno, Raffaella / Giacomet, Vania

    Acta paediatrica (Oslo, Norway : 1992)

    2024  Volume 113, Issue 4, Page(s) 670–676

    Abstract: Aim: The aim of this review was to summarise the most recent evidence about the use of omics-based techniques as an instrument for a more rapid and accurate characterisation of respiratory tract infections, neurological infections and sepsis in ... ...

    Abstract Aim: The aim of this review was to summarise the most recent evidence about the use of omics-based techniques as an instrument for a more rapid and accurate characterisation of respiratory tract infections, neurological infections and sepsis in paediatrics.
    Methods: We performed a narrative review using PubMed and a set of inclusion criteria: English language articles, clinical trials, meta-analysis and reviews including only paediatric population inherited to this topic in the last 15 years.
    Results: The examined studies suggest that host gene expression signatures are an effective method to characterise the different types of infections, to distinguish infection from colonisation and, in some cases, to assess the severity of the disease in children.
    Conclusions: 'Omics-based techniques' may help to define the aetiology of infections in paediatrics, representing a useful tool to choose the most appropriate therapies and limit antibiotic resistance.
    MeSH term(s) Child ; Humans ; Anti-Bacterial Agents/therapeutic use ; Sepsis/diagnosis ; Sepsis/genetics ; Sepsis/drug therapy ; Respiratory Tract Infections ; Gene Expression Profiling ; Language
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2024-01-19
    Publishing country Norway
    Document type Meta-Analysis ; Journal Article ; Review
    ZDB-ID 203487-6
    ISSN 1651-2227 ; 0365-1436 ; 0803-5253
    ISSN (online) 1651-2227
    ISSN 0365-1436 ; 0803-5253
    DOI 10.1111/apa.17119
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Acute Abdomen Due to Torsion of a Wandering Spleen in a Child.

    Giannattasio, Antonietta / Maglione, Marco / Coppola, Crescenzo / Di Candia, Francesca / De Marco, Marianna / Tamasi, Sonia / Tipo, Vincenzo

    Journal of paediatrics and child health

    2022  Volume 58, Issue 9, Page(s) 1704–1705

    MeSH term(s) Abdomen, Acute/etiology ; Child ; Family ; Humans ; Splenectomy ; Splenic Diseases ; Splenic Infarction ; Wandering Spleen/diagnosis ; Wandering Spleen/diagnostic imaging
    Language English
    Publishing date 2022-07-20
    Publishing country Australia
    Document type Letter
    ZDB-ID 1024476-1
    ISSN 1440-1754 ; 1034-4810
    ISSN (online) 1440-1754
    ISSN 1034-4810
    DOI 10.1111/jpc.16124
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Acute Kidney Injury in Children with Acute Appendicitis.

    Marzuillo, Pierluigi / Coppola, Crescenzo / Caiazzo, Roberta / Macchini, Giulia / Di Sessa, Anna / Guarino, Stefano / Esposito, Francesco / Miraglia Del Giudice, Emanuele / Tipo, Vincenzo

    Children (Basel, Switzerland)

    2022  Volume 9, Issue 5

    Abstract: We hypothesized that-as in other common pediatric conditions-acute appendicitis (AA) could be complicated by acute kidney injury (AKI). We aimed to investigate the prevalence of, and the factors associated with AKI in a cohort of patients with AA. We ... ...

    Abstract We hypothesized that-as in other common pediatric conditions-acute appendicitis (AA) could be complicated by acute kidney injury (AKI). We aimed to investigate the prevalence of, and the factors associated with AKI in a cohort of patients with AA. We retrospectively collected data of 122 children (63.9% of male gender; mean age 8.6 ± 2.9 years; range: 2.2-13.9 years) hospitalized for AA. AKI was defined according to the Kidney Disease/Improving Global Outcomes creatinine criteria. We considered a basal serum creatinine value as the value of creatinine estimated with the Hoste (age) equation, assuming that the basal estimated glomerular filtration rate (eGFR) was 120 mL/min/1.73 m
    Language English
    Publishing date 2022-04-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2732685-8
    ISSN 2227-9067
    ISSN 2227-9067
    DOI 10.3390/children9050620
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Polyclonal gammopathy in an adolescent affected by Dent disease 2 and hidradenitis suppurativa.

    Marzuillo, Pierluigi / Caiazzo, Roberta / Coppola, Crescenzo / Camponesco, Ornella / Miraglia Del Giudice, Emanuele / Argenziano, Giuseppe / Manna, Angela La / Piccolo, Vincenzo / Guarino, Stefano

    International journal of dermatology

    2020  Volume 59, Issue 6, Page(s) e201–e203

    MeSH term(s) Acitretin/administration & dosage ; Administration, Cutaneous ; Administration, Oral ; Adolescent ; Drug Therapy, Combination ; Genetic Diseases, X-Linked/blood ; Genetic Diseases, X-Linked/complications ; Genetic Diseases, X-Linked/immunology ; Hidradenitis Suppurativa/blood ; Hidradenitis Suppurativa/drug therapy ; Hidradenitis Suppurativa/immunology ; Humans ; Immunoglobulins/blood ; Immunoglobulins/immunology ; Male ; Minocycline/administration & dosage ; Nephrolithiasis/blood ; Nephrolithiasis/complications ; Nephrolithiasis/immunology ; Paraproteinemias/blood ; Paraproteinemias/diagnosis ; Paraproteinemias/drug therapy ; Paraproteinemias/immunology ; Treatment Outcome
    Chemical Substances Immunoglobulins ; Minocycline (FYY3R43WGO) ; Acitretin (LCH760E9T7)
    Language English
    Publishing date 2020-01-23
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.14789
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Ui VI Zs.189: Show issues Location:
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