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  1. Article ; Online: Multidrug-resistant tuberculous orchiepididymitis: a brief case report.

    Souza, César Augusto Tomaz de / Silva, Jussemara Souza da / Correia, Ademir Silva / Rodrigues, Denise Silva

    Revista do Instituto de Medicina Tropical de Sao Paulo

    2023  Volume 65, Page(s) e61

    Abstract: Tuberculosis (TB) is one of the leading causes of death by infectious diseases worldwide. Multidrug-resistant tuberculosis is a growing problem, especially in countries with high TB prevalence. Although the lungs are the organs most frequently affected ... ...

    Abstract Tuberculosis (TB) is one of the leading causes of death by infectious diseases worldwide. Multidrug-resistant tuberculosis is a growing problem, especially in countries with high TB prevalence. Although the lungs are the organs most frequently affected by this disease, Mycobacterium tuberculosis can harm any organ, including the urogenital tract, causing extrapulmonary tuberculosis, which leads to a challenging diagnosis and consequent treatment delays. In this article, we present a case of orchiepididymitis caused by multidrug-resistant TB (MDR-TB) with a significantly delayed diagnosis, the proposed treatment according to the resistance profile, and the clinical outcomes.
    MeSH term(s) Humans ; Antitubercular Agents/therapeutic use ; Tuberculosis/drug therapy ; Tuberculosis, Multidrug-Resistant/diagnosis ; Tuberculosis, Multidrug-Resistant/drug therapy ; Tuberculosis, Multidrug-Resistant/epidemiology ; Mycobacterium tuberculosis ; Tuberculosis, Extrapulmonary
    Chemical Substances Antitubercular Agents
    Language English
    Publishing date 2023-12-04
    Publishing country Brazil
    Document type Case Reports
    ZDB-ID 128928-7
    ISSN 1678-9946 ; 0036-4665
    ISSN (online) 1678-9946
    ISSN 0036-4665
    DOI 10.1590/S1678-9946202365061
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 292: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Septic shock, hyperferritinemic syndrome, and multiple organ dysfunction without respiratory failure in a patient with disseminated histoplasmosis and advanced HIV disease.

    Silva, Jussemara Souza da / Ernandes, Bruno Correia / Fernandes, Carol Lee Luna / Correia, Ademir Silva / Ponce, Cesar Cilento / Sztajnbok, Jaques / Rodrigues, Camila / Vidal, José Ernesto

    Revista do Instituto de Medicina Tropical de Sao Paulo

    2023  Volume 65, Page(s) e28

    Abstract: AIDS-related disseminated histoplasmosis (DH) can cause septic shock and multiorgan dysfunction with mortality rates of up to 80%. A 41-year-old male presented with fever, fatigue, weight loss, disseminated skin lesions, low urine output, and mental ... ...

    Abstract AIDS-related disseminated histoplasmosis (DH) can cause septic shock and multiorgan dysfunction with mortality rates of up to 80%. A 41-year-old male presented with fever, fatigue, weight loss, disseminated skin lesions, low urine output, and mental confusion. Three weeks before admission, the patient was diagnosed with HIV infection, but antiretroviral therapy (ART) was not initiated. On day 1 of admission, sepsis with multiorgan dysfunction (acute renal failure, metabolic acidosis, hepatic failure, and coagulopathy) was identified. A chest computed tomography showed unspecific findings. Yeasts suggestive of Histoplasma spp. were observed in a routine peripheral blood smear. On day 2, the patient was transferred to the ICU, where his clinical condition progressed with reduced level of consciousness, hyperferritinemia, and refractory septic shock, requiring high doses of vasopressors, corticosteroids, mechanical ventilation, and hemodialysis. Amphotericin B deoxycholate was initiated. On day 3, yeasts suggestive of Histoplasma spp. were observed in the bone marrow. On day 10, ART was initiated. On day 28, samples of peripheral blood and bone marrow cultures revealed Histoplasma spp. The patient stayed in the ICU for 32 days, completing three weeks of intravenous antifungal therapy. After progressive clinical and laboratory improvement, the patient was discharged from the hospital on oral itraconazole, trimethoprim-sulfamethoxazole, and ART. This case highlights the inclusion of DH in the differential diagnosis of patients with advanced HIV disease, septic shock and multiorgan dysfunction but without respiratory failure. In addition, it provides early in-hospital diagnosis and treatment and comprehensive management in the ICU as determining factors for a good outcome.
    MeSH term(s) Male ; Humans ; Adult ; Histoplasmosis/complications ; Histoplasmosis/diagnosis ; Histoplasmosis/drug therapy ; HIV Infections/complications ; Shock, Septic ; Multiple Organ Failure/etiology ; Histoplasma ; Respiratory Insufficiency/etiology
    Language English
    Publishing date 2023-04-14
    Publishing country Brazil
    Document type Case Reports
    ZDB-ID 128928-7
    ISSN 1678-9946 ; 0036-4665
    ISSN (online) 1678-9946
    ISSN 0036-4665
    DOI 10.1590/S1678-9946202365028
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 292: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Abdominal alterations in disseminated paracoccidioidomycosis: computed tomography findings.

    Vermelho, Marli Batista Fernandes / Correia, Ademir Silva / Michailowsky, Tânia Cibele de Almeida / Suzart, Elizete Kazumi Kuniyoshi / Ibanês, Aline Santos / Almeida, Lanamar Aparecida / Khoury, Zarifa / Barba, Mário Flores

    Radiologia brasileira

    2015  Volume 48, Issue 2, Page(s) 81–85

    Abstract: Objective: To evaluate the incidence and spectrum of abdominal computed tomography imaging findings in patients with paracoccidioidomycosis.: Materials and methods: Retrospective analysis of abdominal computed tomography images of 26 patients with ... ...

    Abstract Objective: To evaluate the incidence and spectrum of abdominal computed tomography imaging findings in patients with paracoccidioidomycosis.
    Materials and methods: Retrospective analysis of abdominal computed tomography images of 26 patients with disseminated paracoccidioidomycosis.
    Results: Abnormal abdominal tomographic findings were observed in 18 patients (69.2%), while no significant finding was observed in the other 8 (30.8%) patients.
    Conclusion: Computed tomography has demonstrated to play a relevant role in the screening and detection of abdominal abnormalities in patients with disseminated paracoccidioidomycosis.
    Language English
    Publishing date 2015-05-19
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2078806-X
    ISSN 1678-7099 ; 0100-3984
    ISSN (online) 1678-7099
    ISSN 0100-3984
    DOI 10.1590/0100-3984.2013.0025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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