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  1. Article ; Online: Aripiprazole Monotherapy Was Effective in Treating Obsessive-Compulsive Disorder in a Preschool Boy.

    Coskun, Murat

    Journal of clinical psychopharmacology

    2017  Volume 37, Issue 5, Page(s) 636–637

    MeSH term(s) Antipsychotic Agents/administration & dosage ; Antipsychotic Agents/pharmacology ; Aripiprazole/administration & dosage ; Aripiprazole/pharmacology ; Child Behavior/drug effects ; Child, Preschool ; Humans ; Male ; Obsessive-Compulsive Disorder/drug therapy
    Chemical Substances Antipsychotic Agents ; Aripiprazole (82VFR53I78)
    Language English
    Publishing date 2017-08-08
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 604631-9
    ISSN 1533-712X ; 0271-0749
    ISSN (online) 1533-712X
    ISSN 0271-0749
    DOI 10.1097/JCP.0000000000000748
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1664: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: VEGF, IGF-1 and FGF-2 Serum Levels in Children and Adolescents with Autism Spectrum Disorder with and without Bipolar Disorder.

    Guldiken, Gokce / Karayagmurlu, Ali / Kucukgergin, Canan / Coskun, Murat

    Journal of autism and developmental disorders

    2023  

    Abstract: Purpose: To investigate serum levels of VEGF, IGF-1 and FGF-2, and relationships with several clinical characteristics in children and adolescents with autism spectrum disorder (ASD) with and without bipolar disorder (BD).: Method: 40 subjects with ... ...

    Abstract Purpose: To investigate serum levels of VEGF, IGF-1 and FGF-2, and relationships with several clinical characteristics in children and adolescents with autism spectrum disorder (ASD) with and without bipolar disorder (BD).
    Method: 40 subjects with ASD + BD as study group, and 40 subjects with ASD as control group were included. Serum levels of VEGF, IGF-1, and FGF-2 were measured using commercial enzyme-linked immunosorbent assay kits.
    Results: The study group was significantly higher than the control group in terms of ASD severity, self-harming behavior and sleep disturbance. Serum VEGF and FGF-2 levels were significantly higher in the ASD + BD group than in the control group. There was no significant difference in serum IGF-1 levels between the two groups. There was no correlation between VEGF, IGF-1 and FGF-2 serum levels and ASD severity in the study group. However there was a negative correlation between VEGF levels and age at first diagnosis of BD, and a positive correlation between IGF-1 levels and the number of bipolar episodes in the study group.
    Conclusion: Growth factors like VEGF and FGF-2 may be potential biomarkers of bipolar disorder in young subjects with ASD. Given the difficulty of clinical management of BD in young subjects with ASD, potential biomarkers would help clinicians in the diagnosis and follow up of BD in this special population. Further research is needed whether VEGF and FGF-2 can be potential biomarkers in the clinical management of young subjects with ASD and BD.
    Language English
    Publishing date 2023-09-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391999-7
    ISSN 1573-3432 ; 0162-3257
    ISSN (online) 1573-3432
    ISSN 0162-3257
    DOI 10.1007/s10803-023-06089-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 765: Show issues Location:
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  3. Article ; Online: Laparoscopic Surgery for Adult Intussusception: Case Series.

    Yüksel, Adem / Coşkun, Murat

    The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology

    2021  Volume 32, Issue 8, Page(s) 611–615

    Abstract: Background/aims: Intussusception is a rare condition in adults which accounts for 1% of all intestinal obstructions. It usually requires surgical treatment and the classic approach is laparotomy. This article presented six adult patients who underwent ... ...

    Abstract Background/aims: Intussusception is a rare condition in adults which accounts for 1% of all intestinal obstructions. It usually requires surgical treatment and the classic approach is laparotomy. This article presented six adult patients who underwent laparoscopic surgery for intestinal obstruction due to intussusception.
    Materials and methods: Between January 2017 and July 2019, six adult patients underwent laparoscopic surgery for intestinal obstruction due to intussusception. The patients were evaluated in terms of presenting symptoms, diagnosis, treatment modality, morbidity, mortality and histopathological results.
    Results: All patients presented with acute (50%) or subacute (50%) symptoms. All patients had intestinal obstruction (partial, complete) findings. Intussusception was diagnosed by abdominal computed tomography (CT). The patients with ileocolic and colo-colonic intussusception underwent colonoscopy. In the preoperative period, the etiology of intussusception (neoplasm, idiopathic, etc.) was diagnosed only in one patient (16.6%). Two patients underwent laparoscopic segmental small bowel resection, two patients underwent laparoscopic right hemicolectomy, one patient underwent laparoscopic left hemicolectomy, and one patient underwent laparoscopic anterior resection. None of the patients developed intraoperative or postoperative complication. The histopathological examination revealed malignancy in two patients (33.3%).
    Conclusion: CT is helpful in diagnosing of adult intussusception. However, it is usually difficult to define the underlying pathology with CT. Laparoscopic approach seems to be safe and effective as open surgery, both in diagnosis and treatment of intussusception.
    MeSH term(s) Adult ; Humans ; Intussusception/diagnostic imaging ; Intussusception/surgery ; Laparoscopy/adverse effects ; Tomography, X-Ray Computed ; Treatment Outcome
    Language English
    Publishing date 2021-09-16
    Publishing country Turkey
    Document type Case Reports
    ZDB-ID 1340275-4
    ISSN 2148-5607 ; 1300-4948
    ISSN (online) 2148-5607
    ISSN 1300-4948
    DOI 10.5152/tjg.2020.19835
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4524: Show issues Location:
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  4. Article ; Online: Successful Management of Methylphenidate or Atomoxetine-Related Priapism During Attention-Deficit Hyperactivity Disorder Treatment.

    Karayagmurlu, Ali / Coskun, Murat

    Journal of clinical psychopharmacology

    2020  Volume 40, Issue 3, Page(s) 314–315

    MeSH term(s) Adrenergic Uptake Inhibitors/adverse effects ; Atomoxetine Hydrochloride/adverse effects ; Attention Deficit Disorder with Hyperactivity/drug therapy ; Central Nervous System Stimulants/adverse effects ; Child ; Drug Substitution ; Humans ; Male ; Methylphenidate/adverse effects ; Priapism/chemically induced ; Priapism/drug therapy
    Chemical Substances Adrenergic Uptake Inhibitors ; Central Nervous System Stimulants ; Methylphenidate (207ZZ9QZ49) ; Atomoxetine Hydrochloride (57WVB6I2W0)
    Language English
    Publishing date 2020-04-23
    Publishing country United States
    Document type Letter
    ZDB-ID 604631-9
    ISSN 1533-712X ; 0271-0749
    ISSN (online) 1533-712X
    ISSN 0271-0749
    DOI 10.1097/JCP.0000000000001039
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Aripiprazole Treatment for Obsessive Compulsive Disorder in 2 Young Subjects Who Could Not Tolerate Selective Serotonin Reuptake Inhibitors (SSRIs).

    Coskun, Murat / Karayagmurlu, Ali

    Journal of clinical psychopharmacology

    2020  Volume 40, Issue 3, Page(s) 310–312

    MeSH term(s) Adolescent ; Aripiprazole/therapeutic use ; Child ; Fluoxetine/adverse effects ; Humans ; Male ; Obsessive-Compulsive Disorder/drug therapy ; Serotonin 5-HT1 Receptor Agonists/therapeutic use ; Serotonin Uptake Inhibitors/adverse effects ; Sertraline/adverse effects
    Chemical Substances Serotonin 5-HT1 Receptor Agonists ; Serotonin Uptake Inhibitors ; Fluoxetine (01K63SUP8D) ; Aripiprazole (82VFR53I78) ; Sertraline (QUC7NX6WMB)
    Language English
    Publishing date 2020-04-23
    Publishing country United States
    Document type Case Reports ; Letter
    ZDB-ID 604631-9
    ISSN 1533-712X ; 0271-0749
    ISSN (online) 1533-712X
    ISSN 0271-0749
    DOI 10.1097/JCP.0000000000001210
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Higher Levels of Galectin-1 and Galectin-3 in Young Subjects with Autism Spectrum Disorder Compared to Unaffected Siblings and Healthy Controls.

    Karadogan, Zeynep Nur / Tanir, Yasar / Karayagmurlu, Ali / Kucukgergin, Canan / Coskun, Murat

    Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology

    2023  Volume 21, Issue 4, Page(s) 749–757

    Abstract: Objective: : Despite being highly genetic, the etiology of autism spectrum disorder (ASD), has not yet been clarified. Recent research has focused on the role of neuroinflammation and immune system dysfunction in the pathophysiology of ... ...

    Abstract Objective: : Despite being highly genetic, the etiology of autism spectrum disorder (ASD), has not yet been clarified. Recent research has focused on the role of neuroinflammation and immune system dysfunction in the pathophysiology of neurodevelopmental disorders including ASD. Galectin-1 and galactin-3 are considered among the biomarkers of neuroinflammation and there has been recent reports on the potential role of galectins in the etiology of neurodevelopmental disorders. However, there has been no study examining the relationship between ASD and galectin levels.
    Methods: : Current study aimed to investigate galectin-1 and galectin-3 serum levels in young subjects with ASD comparing with their unaffected siblings and healthy controls.
    Results: : We found significantly higher levels of galectin-1 in case group compared to both unaffected siblings and healthy controls, and higher levels of galectin-3 in case group compared to healthy controls. However, there was no significant association between galectin-1 and galectin-3 levels with the severity of ASD.
    Conclusion: : Findings of our study may support neuroinflammation hypothesis in the etiology of ASD and the potential role of galectin-1 and galectin-3 as biomarkers.
    Language English
    Publishing date 2023-05-30
    Publishing country Korea (South)
    Document type Journal Article
    ZDB-ID 2211550-X
    ISSN 1738-1088
    ISSN 1738-1088
    DOI 10.9758/cpn.23.1052
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6227: Show issues Location:
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  7. Article ; Online: Oversewing the Staple Line: Does It Safe to Prevent Leakage?

    Gönüllü, Emre / Yüksel, Adem / Coşkun, Murat / Harmantepe, Tarık / Fırtına, Gizem / Karaman, Kerem

    Journal of laparoendoscopic & advanced surgical techniques. Part A

    2023  Volume 34, Issue 2, Page(s) 120–126

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Humans ; Obesity, Morbid/surgery ; Surgical Stapling ; Laparoscopy ; Gastrectomy/adverse effects ; Sutures
    Language English
    Publishing date 2023-11-07
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1381909-4
    ISSN 1557-9034 ; 1092-6429
    ISSN (online) 1557-9034
    ISSN 1092-6429
    DOI 10.1089/lap.2023.0284
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    Zs.A 3246: Show issues Location:
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  8. Article ; Online: Peripheral Expression of

    Akköprü, Hilal / Alnak, Alper / Karadoğan, Zeynep Nur / Çağlayan, Ahmet Okay / Özçetin, Mustafa / Coşkun, Murat

    Psychiatry and clinical psychopharmacology

    2023  Volume 33, Issue 1, Page(s) 14–19

    Abstract: Background: The aim of this study was to evaluate the peripheral expression of : Method: This study included 93 children and adolescents with a diagnosis of autism spectrum disorder as the study group and 105 healthy age- and gender-matched controls. ...

    Abstract Background: The aim of this study was to evaluate the peripheral expression of
    Method: This study included 93 children and adolescents with a diagnosis of autism spectrum disorder as the study group and 105 healthy age- and gender-matched controls. Blood samples were obtained from all participants, and a real-time quantitative polymerase chain reaction was performed. Parent- and clinician-rated assessment instruments were used to assess and rate the severity of autism spectrum disorder and other emotional/behavioral problems.
    Results: The mean age of the study group was 9.06 ± 3.57 and 86% were male (n = 83), whereas the mean age of the control group was 9.22 ± 3.86 and 86.7% were male (n = 91). We have found a higher level of peripheral expression of
    Conclusion: ADORA2A
    Language English
    Publishing date 2023-03-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2964147-0
    ISSN 2475-0581 ; 2475-0573
    ISSN (online) 2475-0581
    ISSN 2475-0573
    DOI 10.5152/pcp.2023.22509
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Gynecomastia: A Rare Adverse Effect of Methylphenidate in an Adolescent Boy.

    Karayagmurlu, Ali / Varli, Ayse Tugce / Coskun, Murat

    Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology

    2020  Volume 18, Issue 2, Page(s) 337–339

    Abstract: Gynecomastia is a benign condition developing in association with localized fat deposition and glandular tissue proliferation in the breast in males, and characterized by breast growth. Drug is one of the most important factors in the etiology of ... ...

    Abstract Gynecomastia is a benign condition developing in association with localized fat deposition and glandular tissue proliferation in the breast in males, and characterized by breast growth. Drug is one of the most important factors in the etiology of gynecomastia. Methylphenidate is a commonly preferred and well-tolerated drug in the treatment of attention deficit hyperactivity disorder in children and adolescents. Gynecomastia is an uncommon side-effect of methylphenidate use. We report a case of bilateral gynecomastia developing in a dose-dependent manner during methylphenidate monotherapy and resolving with discontinuation of medication in a 15-year-old patient with a history of a similar side-effect during previous use of the drug. To the best of our knowledge this is one of the few case reports of gynecomastia developing in association with methylphenidate.
    Language English
    Publishing date 2020-04-24
    Publishing country Korea (South)
    Document type Case Reports
    ZDB-ID 2211550-X
    ISSN 1738-1088
    ISSN 1738-1088
    DOI 10.9758/cpn.2020.18.2.337
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: The role of extended antral resection on weight loss and metabolic response after sleeve gastrectomy: A retrospective cohort study.

    Yuksel, Adem / Coskun, Murat / Karaman, Kerem

    Pakistan journal of medical sciences

    2020  Volume 36, Issue 6, Page(s) 1228–1233

    Abstract: Objective: The impact of extended antral resection (AR) after laparoscopic sleeve gastrectomy (LSG) on clinical results is still not clearly elucidated with conflicting results. Our study aimed to determine whether AR is superior to antral preservation ( ...

    Abstract Objective: The impact of extended antral resection (AR) after laparoscopic sleeve gastrectomy (LSG) on clinical results is still not clearly elucidated with conflicting results. Our study aimed to determine whether AR is superior to antral preservation (AP) regarding clinical results.
    Methods: Patients were divided into two groups according to the distance of gastric division as AR group (2cm from pylorus) and AP group (6cm from pylorus). Postoperative excess weight loss percentile (%EWL) and total body weight loss percentiles (%TBWL) at the end of first, 6
    Results: The first 68 patients underwent AP, and the following 43 patients underwent AR. Although statistically not significant, AR achieve more %EWL and %TBWL at the end of the first year, (P>0.05). On the other hand, metabolic parameters were similar at the end of the first year, (P>0.05). Resolution of comorbidities were statistically not different, (P>0.05). Staple line leak occurred in two patients of the AR group (4.7%) and two patients of the AP group (2.9%), (P>0.05).
    Conclusion: Both AR and AP seem to be equally effective in resolution of metabolic response. Although statistically not significant- AR provided more %EWL and %TBWL at the end of 12 months.
    Language English
    Publishing date 2020-08-28
    Publishing country Pakistan
    Document type Journal Article
    ZDB-ID 2032827-8
    ISSN 1681-715X ; 1682-024X ; 1017-4699
    ISSN (online) 1681-715X
    ISSN 1682-024X ; 1017-4699
    DOI 10.12669/pjms.36.6.2321
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