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  1. AU="Costa, Carolina Oliveira"
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  1. Artikel ; Online: Leprosy simulating lichenoid eruption: case report and literature review.

    Sousa, Antônio Renê Diógenes de / Costa, Carolina Oliveira / Queiroz, Hercilia Maria Carvalho / Gonçalves, Paulo Eduardo de Sá / Gonçalves, Heitor de Sá

    Anais brasileiros de dermatologia

    2010  Band 85, Heft 2, Seite(n) 224–226

    Abstract: Leprosy is associated with the occurrence of various skin lesions such as macules, papules, plaques, nodules, and even diffused infiltration, depending on the patient's immune response. Its clinical presentation is often different from the usual pattern, ...

    Abstract Leprosy is associated with the occurrence of various skin lesions such as macules, papules, plaques, nodules, and even diffused infiltration, depending on the patient's immune response. Its clinical presentation is often different from the usual pattern, leading to confusion in diagnosis. The present article describes a rare case of leprosy simulating lichenoid eruption and explores different aspects of the clinical manifestations, diagnosis, and treatment of this nosologic entity.
    Mesh-Begriff(e) Adult ; Diagnosis, Differential ; Female ; Humans ; Leprosy/diagnosis ; Lichenoid Eruptions/diagnosis
    Sprache Englisch
    Erscheinungsdatum 2010-04-05
    Erscheinungsland Spain
    Dokumenttyp Case Reports ; Journal Article ; Review
    ZDB-ID 433655-0
    ISSN 1806-4841 ; 0365-0596
    ISSN (online) 1806-4841
    ISSN 0365-0596
    DOI 10.1590/s0365-05962010000200014
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Cutaneous Rosai-Dorfman disease.

    Landim, Fábio Machado / Rios, Helena de Oliveira / Costa, Carolina Oliveira / Feitosa, Roney Gonçalves Fechine / Rocha Filho, Francisco Dário / Costa, Adriana Alencar Araújo

    Anais brasileiros de dermatologia

    2009  Band 84, Heft 3, Seite(n) 275–278

    Abstract: Rosai-Dorfman disease is a self-limited benign disease. Rosai and Dorfman first described it in 1969, and the etiology of the disease remains unknown. Main manifestations are cervical adenopathy associated with fever, leukocytosis with neutrophilia and ... ...

    Abstract Rosai-Dorfman disease is a self-limited benign disease. Rosai and Dorfman first described it in 1969, and the etiology of the disease remains unknown. Main manifestations are cervical adenopathy associated with fever, leukocytosis with neutrophilia and polyclonal gamaglobulinemia. Although the skin is the most common site of extra nodal disease, Rosai-Dorfman disease restricted to the skin is very rare with only a few cases described in the literature. This paper reports a rare case of cutaneous Rosai-Dorfman with skin as the sole site, and reviews the controversies of diagnosis and treatment.
    Mesh-Begriff(e) Adult ; Histiocytosis, Sinus/pathology ; Histiocytosis, Sinus/surgery ; Humans ; Male ; Skin Diseases/pathology ; Skin Diseases/surgery
    Sprache Portugiesisch
    Erscheinungsdatum 2009-08-05
    Erscheinungsland Spain
    Dokumenttyp Case Reports ; Journal Article ; Review
    ZDB-ID 433655-0
    ISSN 1806-4841 ; 0365-0596
    ISSN (online) 1806-4841
    ISSN 0365-0596
    DOI 10.1590/s0365-05962009000300010
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: The essential oil of Croton zehntneri and trans-anethole improves cutaneous wound healing.

    Cavalcanti, Josenilda Malveira / Leal-Cardoso, José Henrique / Diniz, Lúcio Ricardo Leite / Portella, Viviane Gomes / Costa, Carolina Oliveira / Linard, Cybelle Façanha Barreto Medeiros / Alves, Karuza / Rocha, Maria Valdenir Abreu de Paula / Lima, Crystiane Calado / Cecatto, Vânia Marilande / Coelho-de-Souza, Andrelina Noronha

    Journal of ethnopharmacology

    2012  Band 144, Heft 2, Seite(n) 240–247

    Abstract: Ethnopharmacology relevance: Croton zehntneri is a Euphorbiaceae species native to northeastern Brazil, where teas and beverages made from Croton zehntneri leaves are used as healing agents. To our knowledge, there is no experimental study supporting ... ...

    Abstract Ethnopharmacology relevance: Croton zehntneri is a Euphorbiaceae species native to northeastern Brazil, where teas and beverages made from Croton zehntneri leaves are used as healing agents. To our knowledge, there is no experimental study supporting this claim of pharmacological activity.
    Materials and methods: Full-thickness excisional wounds were made in the left and right sides of the dorsum of anesthetised Swiss mice, and a topical pharmaceutical formulation, developed by including essential oil extracted from the leaves of Croton zehntneri (2% and 20% EOCz) in pluronic-127 (PF-127), was administered to mice twice daily for 15 days post-wounding. To evaluate the contribution of trans-anethole, the major constituent of EOCz (85.7%), in the wound healing activity of EOCz, the effect of the topical administration of trans-AT on wound tissue repair was also evaluated and compared to other groups. A macroscopic analysis of swelling and exudates was performed and scored as 0 (missing), 1 (light), 2 (moderate) and 3 (intense). The number of capillaries and leukocytes was counted in hematoxylin and eosin (HE)-stained sections of the injured tissue. For extracellular matrix remodelling analysis, fibroblasts and collagen fibres present in the photomicrography of the Masson's Trichrome (MT)-stained sections were counted. Each experimental group comprised six mice.
    Results: At day 3 post-wounding, it was observed that treatment with 20% EOCz greatly reduced the swelling and exudates with a similar magnitude to the dexamethasone treatment. The inflammatory cell infiltration and angiogenesis were not altered by either the EOCz- or trans-AT treatments. In contrast, an acceleration of the wound closure was observed, with an enhanced number of fibroblasts and collagen fibres in both the 20% EOCz- and trans-AT-treated mice.
    Conclusion: Our data indicate that EOCz exerts significant wound healing activity, demonstrating its relevant therapeutic potential.
    Mesh-Begriff(e) Animals ; Anisoles/therapeutic use ; Brazil ; Croton ; Medicine, Traditional ; Mice ; Oils, Volatile/therapeutic use ; Phytotherapy ; Plant Leaves ; Wound Healing/drug effects
    Chemische Substanzen Anisoles ; Oils, Volatile ; anethole (Q3JEK5DO4K)
    Sprache Englisch
    Erscheinungsdatum 2012-11-21
    Erscheinungsland Ireland
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 134511-4
    ISSN 1872-7573 ; 0378-8741
    ISSN (online) 1872-7573
    ISSN 0378-8741
    DOI 10.1016/j.jep.2012.08.030
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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