Article: Effect of a Single Apolipoprotein L1 Gene Nephropathy Variant on the Risk of Advanced Lupus Nephritis in Brazilians.
2019 Volume 47, Issue 8, Page(s) 1209–1217
Abstract: Objective: Apolipoprotein L1 gene (: Methods: APOL1 RRA were genotyped in 222 healthy blood donors (controls) and 201 cases with LN from 3 outpatient clinics. Two single-nucleotide polymorphisms in the G1 (rs73885319 and rs60910145) and an indel for ... ...
| Abstract | Objective: Apolipoprotein L1 gene ( Methods: APOL1 RRA were genotyped in 222 healthy blood donors (controls) and 201 cases with LN from 3 outpatient clinics. Two single-nucleotide polymorphisms in the G1 (rs73885319 and rs60910145) and an indel for the G2 (rs71785313) variant were genotyped. Results: The frequency of Conclusion: Although initial kidney lesions and treatment responses were similar, a single |
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| MeSH term(s) | Apolipoprotein L1/genetics ; Genetic Predisposition to Disease ; Genotype ; Humans ; Lupus Nephritis/genetics ; Polymorphism, Single Nucleotide | ||||||||||
| Chemical Substances | APOL1 protein, human ; Apolipoprotein L1 | ||||||||||
| Language | English | ||||||||||
| Publishing date | 2019-11-15 | ||||||||||
| Publishing country | Canada | ||||||||||
| Document type | Journal Article ; Research Support, N.I.H., Extramural | ||||||||||
| ZDB-ID | 194928-7 | ||||||||||
| ISSN | 1499-2752 ; 0315-162X | ||||||||||
| ISSN (online) | 1499-2752 | ||||||||||
| ISSN | 0315-162X | ||||||||||
| DOI | 10.3899/jrheum.190684 | ||||||||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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