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  1. Article ; Online: Implementing a provisional overarching intervention for COVID-19 monitoring and control in the Brazil-Colombia-Peru frontier.

    Contreras, Matilde / Gomes Naveca, Felipe / Carvajal-Cortes, Jose Joaquin / Faviero, Guilherme F / Saavedra, Jorge / Ruback Dos Santos, Eduardo / Alves do Nascimento, Valdinete / Costa de Souza, Victor / Oliveira do Nascimento, Fernanda / Silva E Silva, Dejane / Luz, Sérgio Luiz Bessa / Romero Vesga, Kelly Natalia / Grisales Nieto, Juan Camilo / Avelino-Silva, Vivian I / Benzaken, Adele Schwartz

    Frontiers in public health

    2024  Volume 11, Page(s) 1330347

    Abstract: Introduction: he challenge was to provide comprehensive health resources to a remote and underserved population living in the Brazil-Colombia-Peru border, amid the most disruptive global crisis of the century.: Methods: In August 2021, Fundação ... ...

    Abstract Introduction: he challenge was to provide comprehensive health resources to a remote and underserved population living in the Brazil-Colombia-Peru border, amid the most disruptive global crisis of the century.
    Methods: In August 2021, Fundação Oswaldo Cruz Amazonia (FIOCRUZ Amazônia) and partner collaborators implemented an overarching provisional program for SARS-CoV-2 detection and lineages characterization, training of laboratory personnel and healthcare providers, donation of diagnostic supplies and personal protective equipment, and COVID-19 vaccination. The expedition was conducted at the Port of Tabatinga, a busy terminal with an intense flux of people arriving and departing in boats of all sizes, located in the Amazon River basin. Local government, non-profit organizations, private companies, and other stakeholders supported the intervention.
    Results: The expedition was accomplished in a convergence point, where migrant workers, traders, army personnel, people living in urban areas, and people from small villages living in riversides and indigenous territories are in close and frequent contact, with widespread cross-border movement. Using a boat as a provisional lab and storage facility, the intervention provided clinical and laboratory monitoring for 891 participants; vaccination for 536 individuals; personal protective equipment for 200 healthcare providers; diagnostic supplies for 1,000 COVID-19 rapid tests; training for 42 community health agents on personal protection, rapid test execution, and pulse oximeter management; and hands-on training for four lab technicians on molecular diagnosis.
    Discussion: Our experience demonstrates that multilateral initiatives can counterweigh the scarcity of health resources in underserved regions. Moreover, provisional programs can have a long-lasting effect if investments are also provided for local capacity building.
    MeSH term(s) Male ; Humans ; COVID-19/diagnosis ; COVID-19/prevention & control ; SARS-CoV-2 ; Brazil ; COVID-19 Vaccines ; Colombia ; Peru
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2024-01-08
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2023.1330347
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Genomic and Epidemiological Surveillance of Zika Virus in the Amazon Region.

    Giovanetti, Marta / Faria, Nuno Rodrigues / Lourenço, José / Goes de Jesus, Jaqueline / Xavier, Joilson / Claro, Ingra Morales / Kraemer, Moritz U G / Fonseca, Vagner / Dellicour, Simon / Thézé, Julien / da Silva Salles, Flavia / Gräf, Tiago / Silveira, Paola Paz / do Nascimento, Valdinete Alves / Costa de Souza, Victor / de Melo Iani, Felipe Campos / Castilho-Martins, Emerson Augusto / Cruz, Laura Nogueira / Wallau, Gabriel /
    Fabri, Allison / Levy, Flávia / Quick, Joshua / de Azevedo, Vasco / Aguiar, Renato Santana / de Oliveira, Tulio / Bôtto de Menezes, Camila / da Costa Castilho, Marcia / Terra, Tirza Matos / Souza da Silva, Marineide / Bispo de Filippis, Ana Maria / Luiz de Abreu, André / Oliveira, Wanderson Kleber / Croda, Julio / Campelo de Albuquerque, Carlos F / Nunes, Marcio R T / Sabino, Ester Cerdeira / Loman, Nicholas / Naveca, Felipe Gomes / Pybus, Oliver G / Alcantara, Luiz Carlos

    Cell reports

    2020  Volume 30, Issue 7, Page(s) 2275–2283.e7

    Abstract: Zika virus (ZIKV) has caused an explosive epidemic linked to severe clinical outcomes in the Americas. As of June 2018, 4,929 ZIKV suspected infections and 46 congenital syndrome cases had been reported in Manaus, Amazonas, Brazil. Although Manaus is a ... ...

    Abstract Zika virus (ZIKV) has caused an explosive epidemic linked to severe clinical outcomes in the Americas. As of June 2018, 4,929 ZIKV suspected infections and 46 congenital syndrome cases had been reported in Manaus, Amazonas, Brazil. Although Manaus is a key demographic hub in the Amazon region, little is known about the ZIKV epidemic there, in terms of both transmission and viral genetic diversity. Using portable virus genome sequencing, we generated 59 ZIKV genomes in Manaus. Phylogenetic analyses indicated multiple introductions of ZIKV from northeastern Brazil to Manaus. Spatial genomic analysis of virus movement among six areas in Manaus suggested that populous northern neighborhoods acted as sources of virus transmission to other neighborhoods. Our study revealed how the ZIKV epidemic was ignited and maintained within the largest urban metropolis in the Amazon. These results might contribute to improving the public health response to outbreaks in Brazil.
    MeSH term(s) Brazil/epidemiology ; Epidemiological Monitoring ; Female ; Genomics/methods ; Humans ; Male ; Zika Virus/genetics ; Zika Virus Infection/epidemiology ; Zika Virus Infection/virology
    Language English
    Publishing date 2020-03-04
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2649101-1
    ISSN 2211-1247 ; 2211-1247
    ISSN (online) 2211-1247
    ISSN 2211-1247
    DOI 10.1016/j.celrep.2020.01.085
    Database MEDical Literature Analysis and Retrieval System OnLINE

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