Article: Evaluation of the Performance of the Novodiag
Pathogens (Basel, Switzerland)
2023 Volume 12, Issue 7
Abstract: Objectives: We aimed to assess the performance of the Novodiag: Methods: A panel of 167 selected stool samples was retrospectively analysed with the NSP assay and compared to routine microscopy and qPCR methods for the detection of pathogenic ... ...
| Abstract | Objectives: We aimed to assess the performance of the Novodiag Methods: A panel of 167 selected stool samples was retrospectively analysed with the NSP assay and compared to routine microscopy and qPCR methods for the detection of pathogenic protozoa and microsporidia. Results: Whereas specificity was high for all protozoa and microsporidia, NSP sensitivity was strongly dependent on the comparative method used as reference. When compared to microscopic methods, NSP sensitivity was high (96.7 to 100%) for Conclusions: The overall performance of the NSP assay in the diagnosis of gastrointestinal protozoa and microsporidia seems to be better than or equivalent to that observed with microscopic methods but inferior to that obtainable with classical targeted qPCR. |
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| Language | English |
| Publishing date | 2023-06-29 |
| Publishing country | Switzerland |
| Document type | Journal Article |
| ZDB-ID | 2695572-6 |
| ISSN | 2076-0817 |
| ISSN | 2076-0817 |
| DOI | 10.3390/pathogens12070889 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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