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  1. Article ; Online: A circuit logic for sexually shared and dimorphic aggressive behaviors in Drosophila.

    Chiu, Hui / Hoopfer, Eric D / Coughlan, Maeve L / Pavlou, Hania J / Goodwin, Stephen F / Anderson, David J

    Cell

    2021  Volume 184, Issue 3, Page(s) 847

    Language English
    Publishing date 2021-02-05
    Publishing country United States
    Document type Published Erratum
    ZDB-ID 187009-9
    ISSN 1097-4172 ; 0092-8674
    ISSN (online) 1097-4172
    ISSN 0092-8674
    DOI 10.1016/j.cell.2021.01.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A circuit logic for sexually shared and dimorphic aggressive behaviors in Drosophila.

    Chiu, Hui / Hoopfer, Eric D / Coughlan, Maeve L / Pavlou, Hania J / Goodwin, Stephen F / Anderson, David J

    Cell

    2020  Volume 184, Issue 2, Page(s) 507–520.e16

    Abstract: Aggression involves both sexually monomorphic and dimorphic actions. How the brain implements these two types of actions is poorly understood. We have identified three cell types that regulate aggression in Drosophila: one type is sexually shared, and ... ...

    Abstract Aggression involves both sexually monomorphic and dimorphic actions. How the brain implements these two types of actions is poorly understood. We have identified three cell types that regulate aggression in Drosophila: one type is sexually shared, and the other two are sex specific. Shared common aggression-promoting (CAP) neurons mediate aggressive approach in both sexes, whereas functionally downstream dimorphic but homologous cell types, called male-specific aggression-promoting (MAP) neurons in males and fpC1 in females, control dimorphic attack. These symmetric circuits underlie the divergence of male and female aggressive behaviors, from their monomorphic appetitive/motivational to their dimorphic consummatory phases. The strength of the monomorphic → dimorphic functional connection is increased by social isolation in both sexes, suggesting that it may be a locus for isolation-dependent enhancement of aggression. Together, these findings reveal a circuit logic for the neural control of behaviors that include both sexually monomorphic and dimorphic actions, which may generalize to other organisms.
    MeSH term(s) Aggression/physiology ; Animals ; Drosophila melanogaster/physiology ; Female ; Logic ; Male ; Nerve Net/physiology ; Neurons/physiology ; Sex Characteristics ; Sexual Behavior, Animal/physiology ; Social Isolation ; Tachykinins/metabolism
    Chemical Substances Tachykinins
    Language English
    Publishing date 2020-12-30
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 187009-9
    ISSN 1097-4172 ; 0092-8674
    ISSN (online) 1097-4172
    ISSN 0092-8674
    DOI 10.1016/j.cell.2020.11.048
    Database MEDical Literature Analysis and Retrieval System OnLINE

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