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  1. Article: Neonatal stabilization in Canada: Updates to acute care of at-risk newborns (ACoRN) practices and programming.

    Aylward, Deborah / Coughlin, Kevin

    Paediatrics & child health

    2022  Volume 27, Issue 3, Page(s) 190–191

    Abstract: Disparities in preterm birth and neonatal mortality rates persist in Canada, in part as the result of insufficient training in newborn resuscitation and stabilization care, and inconsistent adherence to best practices. The Neonatal Resuscitation Program ( ...

    Abstract Disparities in preterm birth and neonatal mortality rates persist in Canada, in part as the result of insufficient training in newborn resuscitation and stabilization care, and inconsistent adherence to best practices. The Neonatal Resuscitation Program (NRP) has been the standard of care in all facilities providing perinatal care in Canada since the 1990s, but perinatal care providers and educators have continued to recognize gaps in knowledge and skill when stabilizing newborns post-resuscitation, especially in settings where this care is encountered infrequently. The Acute Care of at-Risk Newborns (ACoRN) program was developed to bridge such gaps. In ACoRN, an initial Primary Survey and systems-based care pathways (Sequences) prioritize and guide the assessment, essential care, and management of at-risk or unwell newborns in the first hours and days of life. This practice point highlights changes to practice and recommendations since 2012, when the ACoRN text and program were last revised. Like NRP, ACoRN is administered in Canada by the Canadian Paediatric Society (CPS). A newly revised and updated textbook and teaching program, both launched in 2021, will standardize care, increase competence and confidence among perinatal care providers, and improve neonatal outcomes in Canada and elsewhere in years to come.
    Language English
    Publishing date 2022-06-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2106767-3
    ISSN 1918-1485 ; 1205-7088
    ISSN (online) 1918-1485
    ISSN 1205-7088
    DOI 10.1093/pch/pxac029
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: La stabilisation néonatale au Canada : des mises à jour aux pratiques du Programme de soins aigus aux nouveau-nés à risque (ACoRN).

    Aylward, Deborah / Coughlin, Kevin

    Paediatrics & child health

    2022  Volume 27, Issue 3, Page(s) 191

    Abstract: On constate des écarts dans les taux de prématurité et de mortalité néonatale au Canada, en partie à cause d'une formation insuffisante en réanimation et en stabilisation néonatales et de même que d'une adhésion inégale aux pratiques exemplaires. Depuis ... ...

    Abstract On constate des écarts dans les taux de prématurité et de mortalité néonatale au Canada, en partie à cause d'une formation insuffisante en réanimation et en stabilisation néonatales et de même que d'une adhésion inégale aux pratiques exemplaires. Depuis les années 1990, le Programme de réanimation néonatale est la norme dans tous les établissements qui prodiguent des soins périnatals, mais les fournisseurs et les formateurs de soins périnatals ont continué d'observer des lacunes sur le plan des connaissances et des habiletés en matière de stabilisation des nouveau-nés après la réanimation, particulièrement dans les milieux où ces soins sont rarement requis. Le Programme de soins aigus aux nouveau-nés à risque (ACoRN) a été mis sur pied pour corriger ces lacunes. Dans l'ACoRN, une évaluation primaire et des trajectoires pour soigner les divers systèmes organiques (les séquences) priorisent et orientent l'évaluation, les soins essentiels et la prise en charge des nouveau-nés à risque ou malades pendant les premières heures et les premiers jours de vie. Le présent point de pratique fait ressortir les changements aux pratiques et aux recommandations depuis 2012, année de la dernière révision du texte et du fonctionnement de l'ACoRN, qui n'était alors offert qu'en anglais. À l'instar du Programme de réanimation néonatale, l'ACoRN est géré par la Société canadienne de pédiatrie au Canada. Un manuel et un programme d'enseignement révisés, mis à jour, traduits en français et lancés en 2021 standardiseront les soins, accroîtront les compétences et la confiance chez les dispensateurs de soins périnatals et amélioreront les pronostics néonatals au Canada et ailleurs au cours des prochaines années.
    Language English
    Publishing date 2022-06-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2106767-3
    ISSN 1918-1485 ; 1205-7088
    ISSN (online) 1918-1485
    ISSN 1205-7088
    DOI 10.1093/pch/pxac030
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Medical decision-making in paediatrics: Infancy to adolescence.

    Coughlin, Kevin W

    Paediatrics & child health

    2018  Volume 23, Issue 2, Page(s) 138–146

    Abstract: Medical decision-making in the paediatric population is complicated by the wide variation in physical and psychological development that occurs as children progress from infancy to adolescence. Parents and legal guardians are the de facto decision-makers ...

    Abstract Medical decision-making in the paediatric population is complicated by the wide variation in physical and psychological development that occurs as children progress from infancy to adolescence. Parents and legal guardians are the de facto decision-makers in early infancy, but thereafter, the roles of parents/legal guardians and paediatric patients become ever more complex. Health care providers (HCPs), while not decision-makers per se, have a significant role in medical decision-making throughout childhood. This statement outlines the ethical principles of medical decision-making for HCPs involved in caring for paediatric patients. This revision focuses on individual decision-making in the context of the patient-provider relationship and provides increased guidance for dealing with disagreements.
    Language French
    Publishing date 2018-04-12
    Publishing country England
    Document type Journal Article ; Review ; Comment
    ZDB-ID 2106767-3
    ISSN 1918-1485 ; 1205-7088
    ISSN (online) 1918-1485
    ISSN 1205-7088
    DOI 10.1093/pch/pxx127
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Extremely low gestational age neonates and resuscitation: survey on perspectives of Canadian neonatologists.

    Wood, Stacie J / Coughlin, Kevin / Cheng, Anita

    Journal of perinatal medicine

    2022  Volume 50, Issue 9, Page(s) 1256–1263

    Abstract: Objectives: Resuscitation care planning for extremely low gestational age neonates (ELGANs) is complex and ethically charged. Increasing survival at lower gestational ages has had a significant impact on this complexity. It also has an impact on ... ...

    Abstract Objectives: Resuscitation care planning for extremely low gestational age neonates (ELGANs) is complex and ethically charged. Increasing survival at lower gestational ages has had a significant impact on this complexity. It also has an impact on healthcare resource utilization and policy development in Canada. This study sought to determine the current attitudes and practices of neonatologists in Canada, and to assess moral distress associated with resuscitation decisions in the ELGAN population. It also aimed to explore the perspectives of adopting a shared decision-making approach where further data with regard to best interests and prognosis are gathered in an individualized manner after birth.
    Methods: Neonatologists in Canadian level III NICUs were surveyed in 2020.
    Results: Amongst the 65 responses, 78% expressed moral distress when parents request non-resuscitation at 24 weeks. Uncertainty around long-term outcomes in an era with improved chances of morbidity-free survival was the most prominent factor contributing to moral distress. 70% felt less moral distress deciding goals of care after the baby's initial resuscitation and preferred an individualized approach to palliation decisions based on postnatal course and assessment.
    Conclusions: While most current guidelines still support the option of non-resuscitation for infants born at less than 25 weeks, we show evidence of moral distress among Canadian neonatologists that suggests the consideration of routine resuscitation from 24 weeks and above is a more ethical approach in the current era of improved outcomes. Canadian neonatologists identified less moral distress when goals of care are developed postnatally, with availability of more evidence for prognostication, instead of antenatally based primarily on gestational age.
    MeSH term(s) Infant, Newborn ; Humans ; Gestational Age ; Neonatologists ; Infant, Premature ; Attitude of Health Personnel ; Canada ; Resuscitation Orders
    Language English
    Publishing date 2022-07-11
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 123512-6
    ISSN 1619-3997 ; 0300-5577 ; 0936-174X
    ISSN (online) 1619-3997
    ISSN 0300-5577 ; 0936-174X
    DOI 10.1515/jpm-2022-0089
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Phenotypes of Obstructive Sleep Apnea.

    Coughlin, Kevin / Davies, George M / Gillespie, Marion Boyd

    Otolaryngologic clinics of North America

    2020  Volume 53, Issue 3, Page(s) 329–338

    Abstract: Obstructive sleep apnea (OSA) is a multisystem breathing disorder associated with increased morbidity and mortality. Clinical and operative assessment tools improve surgical approaches to treat airway obstruction. The primary sites of anatomic ... ...

    Abstract Obstructive sleep apnea (OSA) is a multisystem breathing disorder associated with increased morbidity and mortality. Clinical and operative assessment tools improve surgical approaches to treat airway obstruction. The primary sites of anatomic obstruction are at the levels of the nasal, palatal, and hypopharyngeal airway. The literature suggests a relationship between reduced neuromuscular tone and the age-related increase in OSA prevalence for normal-weight adults. Pharyngeal soft tissue collapse due to reduced airway pressure is defined as the critical closing pressure. Respiratory biochemistry homeostasis is an additional factor in maintaining airway patency.
    MeSH term(s) Aging/pathology ; Aging/physiology ; Arousal/physiology ; Continuous Positive Airway Pressure ; Humans ; Pharynx/physiopathology ; Phenotype ; Pressure ; Respiration ; Respiratory System/physiopathology ; Sleep ; Sleep Apnea, Obstructive/physiopathology ; Sleep Apnea, Obstructive/therapy
    Language English
    Publishing date 2020-04-23
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 417489-6
    ISSN 1557-8259 ; 0030-6665
    ISSN (online) 1557-8259
    ISSN 0030-6665
    DOI 10.1016/j.otc.2020.02.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Dual diagnosis of trisomy 21 and lethal perinatal Gaucher disease as a cause of non-immune hydrops fetalis in a twin pregnancy for a consanguineous couple.

    Al Harthy, Talib / Colaiacovo, Samantha / Gratton, Robert J / Coughlin, Kevin / Siu, Victoria Mok / Prasad, Chitra / Rupar, Charles / Saleh, Maha

    Clinical case reports

    2023  Volume 11, Issue 8, Page(s) e7827

    Abstract: Non-immune hydrops is a prenatal finding which can occur due to an underlying genetic diagnosis such as common chromosomal aneuploidy (Trisomy 21, Turner syndrome etc.). It is extremely rare to have more than one genetic cause of hydrops fetalis in a ... ...

    Abstract Non-immune hydrops is a prenatal finding which can occur due to an underlying genetic diagnosis such as common chromosomal aneuploidy (Trisomy 21, Turner syndrome etc.). It is extremely rare to have more than one genetic cause of hydrops fetalis in a single pregnancy. This report describes a dichorionic diamniotic pregnancy for a consanguineous couple where noninvasive prenatal testing was "high risk" for Trisomy 21. Family declined amniocentesis and opted for postnatal genetic testing. The pregnancy was later complicated with severe hydrops fetalis leading to demise for one of the twins, and a premature delivery of the other twin who had remarkable collodion not in keeping with Trisomy 21. Postnatal genetic investigations confirmed both Trisomy 21 and prenatal lethal Gaucher disease in the survivor twin. This case report highlights some of the prenatal diagnostic challenges for a consanguineous couple where a rare cause of fetal hydrops was concealed in a setting of a common chromosomal aneuploidy. The prompt postnatal diagnosis of perinatal lethal Gaucher disease, confirmed with undetectable glucocerebrosidase enzyme activity, assisted the family in the decision of providing palliative care for their infant who was quickly deteriorating. The importance of postnatal genetic evaluation and its impact on immediate patient management in an NICU setting is emphasized. This dual diagnosis was significant for the couple as it explained pervious pregnancy losses and has important future recurrence risk implications.
    Language English
    Publishing date 2023-08-23
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.7827
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: The relationship between paediatric practitioners and 'industry'.

    Albersheim, Susan / Coughlin, Kevin

    Paediatrics & child health

    2017  Volume 22, Issue 6, Page(s) 357–362

    Abstract: Paediatric practitioners interact with industry representatives for many purposes but most often to receive information on new and existing products. While practitioners believe they are immune to the marketing influences exerted by these representatives, ...

    Abstract Paediatric practitioners interact with industry representatives for many purposes but most often to receive information on new and existing products. While practitioners believe they are immune to the marketing influences exerted by these representatives, research has demonstrated otherwise. The literature suggests that the public is aware of such influences and that most people feel industry influence on practitioners is inappropriate. National guidelines go some way toward regulating practitioner-industry interactions, although they are not always clear or sufficient. The present practice point explores the context for these relationships, raises some ethical issues specific to paediatric practitioners and provides recommendations for maintaining professional integrity in the patient-physician relationship. Paediatric practitioners have a professional duty to ensure that their own interactions with industry are conducted with the best interests of the patient front and centre.
    Language French
    Publishing date 2017-08-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 2106767-3
    ISSN 1918-1485 ; 1205-7088
    ISSN (online) 1918-1485
    ISSN 1205-7088
    DOI 10.1093/pch/pxx096
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Respiratory Morbidity in Late Preterm and Term Babies Born by Elective Caesarean Section.

    Ahimbisibwe, Asa / Coughlin, Kevin / Eastabrook, Genevieve

    Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC

    2019  Volume 41, Issue 8, Page(s) 1144–1149

    Abstract: Objective: This study sought to determine the incidence and severity of respiratory morbidity among late preterm and term babies born by elective Caesarean section (CS) in London, Ontario.: Methods: A retrospective chart review was conducted of all ... ...

    Abstract Objective: This study sought to determine the incidence and severity of respiratory morbidity among late preterm and term babies born by elective Caesarean section (CS) in London, Ontario.
    Methods: A retrospective chart review was conducted of all elective CSs performed at or beyond 36
    Results: The main indications for elective CS were previous CS (59.3%) and malpresentation (24.2%). The majority of elective CSs were performed at 38 weeks (34.1%) and 39 weeks (40.1%). Although only 3.7% of babies born by elective CS were found to have respiratory morbidity, 85% of these babies were admitted to the neonatal intensive care unit (NICU), and 15% required additional observation through a triage period. The relative risk of respiratory morbidity with elective CS at ≤38
    Conclusion: The risk of respiratory morbidity was significantly higher following elective CS before 39 weeks gestation. This resulted in increased length of stay and increased requirements for intravenous lines, blood draws, and exposure to antibiotics. This study provides further evidence that uncomplicated elective CS should be performed at ≥39 weeks, and interventions, such as preoperative antenatal steroid administration, may be considered if elective CS is medically indicated before 39 weeks.
    MeSH term(s) Adrenal Cortex Hormones/therapeutic use ; Apgar Score ; Cesarean Section/adverse effects ; Elective Surgical Procedures/adverse effects ; Female ; Gestational Age ; Humans ; Incidence ; Infant, Newborn ; Infant, Premature ; Intensive Care Units, Neonatal ; Length of Stay ; Ontario/epidemiology ; Postoperative Complications/epidemiology ; Postoperative Complications/therapy ; Pregnancy ; Prenatal Care ; Respiratory Distress Syndrome, Newborn/epidemiology ; Respiratory Distress Syndrome, Newborn/therapy ; Respiratory Therapy ; Retrospective Studies ; Risk Factors
    Chemical Substances Adrenal Cortex Hormones
    Language English
    Publishing date 2019-01-12
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2171082-X
    ISSN 1701-2163
    ISSN 1701-2163
    DOI 10.1016/j.jogc.2018.11.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Association between distress and displacement settings: a cross-sectional survey among displaced Yazidis in northern Iraq.

    Pham, Phuong N / Fozouni, Laila / Al-Saiedi, Abdulrazzaq / Coughlin, Kevin / Vinck, Patrick

    BMC public health

    2021  Volume 21, Issue 1, Page(s) 679

    Abstract: Background: Globally 70.8 million people have been forcibly displaced from their homes and are at disproportionally high risk for trauma. At the time of this study, there was an estimated 1.6 million internally displaced persons (IDP) in Iraq, more than ...

    Abstract Background: Globally 70.8 million people have been forcibly displaced from their homes and are at disproportionally high risk for trauma. At the time of this study, there was an estimated 1.6 million internally displaced persons (IDP) in Iraq, more than two-thirds of whom reside in private, urban settings. This study aims to understand the impact of post-displacement accommodation on mental well-being of the Yazidi minority group displaced in Iraq.
    Methods: Multi-stage stratified sampling was used to randomly select IDPs in camp and out of camp settlements in northern Iraq. Standardized questionnaires evaluated factors including exposure to violence and self-reported distress symptoms (measured by Impact of Event Scale-Revised). A multi-variate linear model assessed the relationship between settlement setting and distress symptoms.
    Results: One thousand two hundred fifty-six displaced Yazidi participants were included in the study: 63% in camps and 37% out of camps. After controlling for exposure to violence, social cohesion, unemployment, and access to basic services, IDPs in camps were predicted to have a 19% higher mean distress symptom score compared to those out of camps.
    Conclusions: This study provides a framework to investigate post-displacement accommodation as a potential intervention to improve well-being for displaced populations. With a shift towards new models of emergency and long-term housing, it is important to understand the potential and limitations of more decentralized models, and identify effective methods to maintain access to basic services while improving living conditions for both displaced populations and their host communities.
    MeSH term(s) Cross-Sectional Studies ; Humans ; Iraq/epidemiology ; Mental Health ; Refugees ; Violence
    Language English
    Publishing date 2021-04-08
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1471-2458
    ISSN (online) 1471-2458
    DOI 10.1186/s12889-021-10734-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Parent-Integrated Interventions to Improve Language Development in Children Born Very Preterm.

    Synnes, Anne / Luu, Thuy Mai / Afifi, Jehier / Khairy, May / de Cabo, Cecilia / Moddemann, Diane / Hendson, Leonora / Reichert, Amber / Coughlin, Kevin / Nguyen, Kim Anh / Richter, Lindsay L / Bacchini, Fabiana / Aziz, Khalid

    Children (Basel, Switzerland)

    2023  Volume 10, Issue 6

    Abstract: Neurodevelopmental challenges in children born very preterm are common and not improving. This study tested the feasibility of using Evidence-based Practice to Improve Quality (EPIQ), a proven quality improvement technique that incorporates scientific ... ...

    Abstract Neurodevelopmental challenges in children born very preterm are common and not improving. This study tested the feasibility of using Evidence-based Practice to Improve Quality (EPIQ), a proven quality improvement technique that incorporates scientific evidence to target improving language abilities in very preterm populations in 10 Canadian neonatal follow-up programs. Feasibility was defined as at least 70% of sites completing four intervention cycles and 75% of cycles meeting targeted aims. Systematic reviews were reviewed and performed, an online quality improvement educational tool was developed, multidisciplinary teams that included parents were created and trained, and sites provided virtual support to implement and audit locally at least four intervention cycles of approximately 6 months in duration. Eight of ten sites implemented at least four intervention cycles. Of the 48 cycles completed, audits showed 41 (85%) met their aim. Though COVID-19 was a barrier, parent involvement, champions, and institutional support facilitated success. EPIQ is a feasible quality improvement methodology to implement family-integrated evidence-informed interventions to support language interventions in neonatal follow-up programs. Further studies are required to identify potential benefits of service outcomes, patients, and families and to evaluate sustainability.
    Language English
    Publishing date 2023-05-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2732685-8
    ISSN 2227-9067
    ISSN 2227-9067
    DOI 10.3390/children10060953
    Database MEDical Literature Analysis and Retrieval System OnLINE

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