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  1. Article ; Online: Letter regarding "Evaluation of the clinical outcome of hypercalcemia of malignancy and concurrent azotemia in dogs with lymphoma".

    Couto, C Guillermo / Chew, Dennis J

    Journal of veterinary internal medicine

    2024  

    Language English
    Publishing date 2024-03-29
    Publishing country United States
    Document type Letter
    ZDB-ID 92798-3
    ISSN 1939-1676 ; 0891-6640
    ISSN (online) 1939-1676
    ISSN 0891-6640
    DOI 10.1111/jvim.17060
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4095: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Serum Symmetric Dimethylarginine Concentration in Greyhound Pups and Adults.

    Couto, C Guillermo / Murphy, Rachel / Coyne, Michael / Drake, Corie

    Topics in companion animal medicine

    2021  Volume 45, Page(s) 100558

    Abstract: Greyhounds have developed numerous physiologic and hematologic adaptations specific to the breed. Adult Greyhounds have significantly higher serum creatinine (sCr) concentrations than non-Greyhound dogs; this is primarily attributed to their large muscle ...

    Abstract Greyhounds have developed numerous physiologic and hematologic adaptations specific to the breed. Adult Greyhounds have significantly higher serum creatinine (sCr) concentrations than non-Greyhound dogs; this is primarily attributed to their large muscle mass. Adult Greyhounds also have significantly higher symmetric dimethylarginine (SDMA) concentrations than non-Greyhound dogs. In this study we evaluated serum SDMA and sCr concentrations in 48 Greyhound pups from 11 litters, with no exposure to racing, in order to determine if the higher SDMA or sCr concentration in adults is a breed-related trait or is associated with extra-physiological causes (e.g., racing environment, drug administration, etc.). The distribution of SDMA concentration for all the pups (mean: 0.70 µmol/L; 95% CI: 0.70-0.74 µmol/L) was not statistically different from that found in a group of 183 adult Greyhounds; whereas, distribution of sCr concentration in the pups (mean: 76.9 µmol/L; 95% CI: 70.7-83.1 µmol/L) was significantly different than that observed in adult Greyhounds, suggesting that the 2 samples were drawn from different populations. This study provides evidence to support that the higher serum SDMA concentration in Greyhounds is a breed-related trait.
    MeSH term(s) Animals ; Arginine/analogs & derivatives ; Dogs ; Records/veterinary
    Chemical Substances symmetric dimethylarginine (49787G1ULV) ; Arginine (94ZLA3W45F)
    Language English
    Publishing date 2021-07-08
    Publishing country United States
    Document type Journal Article
    ISSN 1946-9837
    ISSN (online) 1946-9837
    DOI 10.1016/j.tcam.2021.100558
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Serum Symmetric Dimethylarginine Concentration in Greyhound Pups and Adults

    Couto, C. Guillermo / Murphy, Rachel / Coyne, Michael / Drake, Corie

    Topics in companion animal medicine. 2021 Nov., v. 45

    2021  

    Abstract: Greyhounds have developed numerous physiologic and hematologic adaptations specific to the breed. Adult Greyhounds have significantly higher serum creatinine (sCr) concentrations than non-Greyhound dogs; this is primarily attributed to their large muscle ...

    Abstract Greyhounds have developed numerous physiologic and hematologic adaptations specific to the breed. Adult Greyhounds have significantly higher serum creatinine (sCr) concentrations than non-Greyhound dogs; this is primarily attributed to their large muscle mass. Adult Greyhounds also have significantly higher symmetric dimethylarginine (SDMA) concentrations than non-Greyhound dogs. In this study we evaluated serum SDMA and sCr concentrations in 48 Greyhound pups from 11 litters, with no exposure to racing, in order to determine if the higher SDMA or sCr concentration in adults is a breed-related trait or is associated with extra-physiological causes (e.g., racing environment, drug administration, etc.). The distribution of SDMA concentration for all the pups (mean: 0.70 µmol/L; 95% CI: 0.70-0.74 µmol/L) was not statistically different from that found in a group of 183 adult Greyhounds; whereas, distribution of sCr concentration in the pups (mean: 76.9 µmol/L; 95% CI: 70.7-83.1 µmol/L) was significantly different than that observed in adult Greyhounds, suggesting that the 2 samples were drawn from different populations. This study provides evidence to support that the higher serum SDMA concentration in Greyhounds is a breed-related trait.
    Keywords Greyhound ; adults ; blood serum ; creatinine ; drugs ; medicine ; muscle tissues ; pets
    Language English
    Dates of publication 2021-11
    Publishing place Elsevier Inc.
    Document type Article
    ISSN 1938-9736
    DOI 10.1016/j.tcam.2021.100558
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: Effect of packed red blood cell transfusion on thromboelastographic tracings in dogs with naturally occurring anemia.

    Brooks, Aimee C / Cooper, Edward S / Couto, C Guillermo / Guillaumin, Julien

    American journal of veterinary research

    2020  Volume 81, Issue 6, Page(s) 499–505

    Abstract: Objective: To assess the effect of packed RBC (pRBC) transfusion on thromboelastographic (TEG) tracings in dogs with naturally occurring anemia.: Animals: 22 clinically anemic dogs that received a pRBC transfusion.: Procedures: For each dog, a ... ...

    Abstract Objective: To assess the effect of packed RBC (pRBC) transfusion on thromboelastographic (TEG) tracings in dogs with naturally occurring anemia.
    Animals: 22 clinically anemic dogs that received a pRBC transfusion.
    Procedures: For each dog, a blood sample was collected before and within 3 hours after completion of the pRBC transfusion for a CBC, nonactivated TEG analysis, and measurement of blood viscosity. Wilcoxon signed rank tests were used to compare CBC, viscosity, and TEG variables between pretransfusion and posttransfusion blood samples. Multivariable linear regression was used to assess the effects of pretransfusion-posttransfusion changes in Hct, WBC count, and platelet count on changes in TEG variables.
    Results: Median posttransfusion Hct (21%; range, 13% to 34%) was significantly greater than the median pretransfusion Hct (12.5%; range, 7% to 29%). Packed RBC transfusion was associated with a median increase in Hct of 6.2% (range, 1.2% to 13%). Maximum amplitude significantly decreased from 74.9 to 73.8 mm and clot strength significantly decreased from 14,906 to 14,119 dynes/s after pRBC transfusion. Blood viscosity significantly increased, whereas platelet and WBC counts significantly decreased after transfusion. Multivariable linear regression revealed that pretransfusion-posttransfusion changes in Hct, WBC count, and platelet count were not associated with changes in TEG variables.
    Conclusions and clinical relevance: Results indicated that pRBC transfusion had only small effects on the TEG tracings of hemodynamically stable dogs. Therefore, large changes in TEG tracings following pRBC transfusion are unlikely to be the result of the transfusion and should be investigated further.
    MeSH term(s) Anemia/veterinary ; Animals ; Blood Transfusion/veterinary ; Dog Diseases ; Dogs ; Erythrocyte Transfusion/veterinary ; Hematocrit/veterinary ; Thrombelastography/veterinary
    Language English
    Publishing date 2020-06-24
    Publishing country United States
    Document type Journal Article
    ZDB-ID 390796-x
    ISSN 1943-5681 ; 0002-9645
    ISSN (online) 1943-5681
    ISSN 0002-9645
    DOI 10.2460/ajvr.81.6.499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 422: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Improving quality control for in-clinic hematology analyzers: Common myths and opportunities.

    Michael, Helen T / Nabity, Mary B / Couto, C Guillermo / Moritz, Andreas / Harvey, John W / DeNicola, Dennis B / Hammond, Jeremy M

    Veterinary clinical pathology

    2022  Volume 51, Issue 3, Page(s) 302–310

    MeSH term(s) Animals ; Hematology ; Platelet Count/veterinary ; Quality Control
    Language English
    Publishing date 2022-09-12
    Publishing country United States
    Document type Letter
    ZDB-ID 2114702-4
    ISSN 1939-165X ; 0275-6382
    ISSN (online) 1939-165X
    ISSN 0275-6382
    DOI 10.1111/vcp.13154
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

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  6. Article ; Online: Hyperkalemia during general anesthesia in two Greyhounds.

    Jones, Stacey J / Mama, Khursheed R / Brock, Nancy K / Couto, C Guillermo

    Journal of the American Veterinary Medical Association

    2019  Volume 254, Issue 11, Page(s) 1329–1334

    Abstract: Case description: A 36-kg (79-lb) castrated male Greyhound (dog 1) and a 25-kg (55 lb) spayed female Greyhound (dog 2) underwent general anesthesia for dental care with similar perianesthetic protocols on multiple occasions from 2013 to 2016. Both dogs ... ...

    Abstract Case description: A 36-kg (79-lb) castrated male Greyhound (dog 1) and a 25-kg (55 lb) spayed female Greyhound (dog 2) underwent general anesthesia for dental care with similar perianesthetic protocols on multiple occasions from 2013 to 2016. Both dogs had periodontal disease but were otherwise deemed healthy. Both dogs developed clinically relevant hyperkalemia, with signs including loss of P waves on ECG tracings, during multiple anesthetic events.
    Clinical findings: Dog 1 developed hyperkalemia during 2 of 2 anesthetic events, with ECG changes noted during the first event. Dog 2 developed hyperkalemia during 3 of 4 anesthetic events, with ECG changes identified during the second and third events. Serum potassium concentration for both dogs was within the reference range prior to and between anesthetic events. No underlying etiopathogenesis for hyperkalemia was identified for either dog.
    Treatment and outcome: In each hyperkalemic event, the clinician stopped the dental procedure and continued to provide supportive care and monitoring while the dog recovered from anesthesia. The ECG changes resolved, and serum potassium concentration returned to the reference range rapidly after inhalant anesthetic administration was discontinued. The dogs were discharged from the hospital without further complications.
    Clinical relevance: Hyperkalemia in anesthetized Greyhounds resulted in serious cardiac conduction abnormalities, which could be potentially fatal if not recognized and promptly treated. Further investigation into the etiopathogenesis, prevention and treatment strategies, and genetic or familial components of this condition is indicated.
    MeSH term(s) Anesthesia, General/veterinary ; Animals ; Dog Diseases/diagnosis ; Dogs ; Female ; Hyperkalemia/diagnosis ; Hyperkalemia/veterinary ; Male
    Language English
    Publishing date 2019-05-08
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 390811-2
    ISSN 1943-569X ; 0003-1488
    ISSN (online) 1943-569X
    ISSN 0003-1488
    DOI 10.2460/javma.254.11.1329
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 423: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  7. Book: Small animal internal medicine

    Nelson, Richard W / Couto, C. Guillermo

    2014  

    Author's details [edited by] Richard W. Nelson, C. Guillermo Couto
    MeSH term(s) Dog Diseases ; Cat Diseases ; Veterinary Medicine/methods
    Language English
    Size xxix, 1473 pages :, illustrations, portraits
    Edition Fifth edition.
    Document type Book
    ISBN 9780323086820 ; 0323086829
    Database Catalogue of the US National Library of Medicine (NLM)

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  8. Book: Small animal internal medicine

    Couto, C. Guillermo / Nelson, Richard William

    2014  

    Author's details [edited by] Richard W. Nelson, C. Guillermo Couto
    MeSH term(s) Cat Diseases ; Dog Diseases ; Veterinary Medicine/methods
    Keywords Cats/Diseases ; Dogs/Diseases ; Veterinary internal medicine
    Language English
    Size XXIX, 1473 S., Ill., graph. Darst.
    Edition Fifth edition
    Publisher Elsevier/Mosby
    Publishing place St. Louis, Mo
    Document type Book
    Note Includes bibliographical references and index
    ISBN 9780323086820 ; 0323086829
    Database Special collection on veterinary medicine and general parasitology

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  9. Book ; Online: Small animal internal medicine

    Couto, C. Guillermo / Nelson, Richard William

    2014  

    Author's details [edited by] Richard W. Nelson, DVM, DACVIM (Internal medicine), C. Guillermo Couto, DVM, DACVIM (Internal medicine and oncology)
    MeSH term(s) Cat Diseases ; Dog Diseases ; Veterinary Medicine/methods
    Keywords Cats/Diseases ; Dogs/Diseases ; Veterinary internal medicine
    Language English
    Size Online-Ressource (xxix, 1473 pages), color illustrations
    Edition Fifth edition
    Publisher Elsevier
    Publishing place St. Louis, Mo
    Document type Book ; Online
    Note Includes bibliographical references and index
    ISBN 0323086829 ; 0323243002 ; 9780323086820 ; 9780323243001
    Database Special collection on veterinary medicine and general parasitology

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  10. Article: Outcome and treatments of dogs with aortic thrombosis: 100 cases (1997‐2014)

    Ruehl, Mackenzie / Lynch, Alex M / O'Toole, Therese E / Morris, Bari / Rush, John / Couto, C. Guillermo / Hmelo, Samantha / Sonnenshein, Stacey / Butler, Amy / Guillaumin, Julien

    Journal of veterinary internal medicine. 2020 Sept., v. 34, no. 5

    2020  

    Abstract: BACKGROUND: Aortic thrombosis (ATh) is an uncommon condition in dogs, with limited understanding of risks factors, outcomes, and treatments. OBJECTIVES/HYPOTHESIS: To describe potential risk factors, outcome, and treatments in dogs with ATh. ANIMALS: ... ...

    Abstract BACKGROUND: Aortic thrombosis (ATh) is an uncommon condition in dogs, with limited understanding of risks factors, outcomes, and treatments. OBJECTIVES/HYPOTHESIS: To describe potential risk factors, outcome, and treatments in dogs with ATh. ANIMALS: Client‐owned dogs with a diagnosis of ATh based on ultrasonographic or gross necropsy examination. METHOD: Multicentric retrospective study from 2 academic institutions. RESULTS: One hundred dogs were identified. Anti‐thrombin diagnosis, 35/100 dogs were nonambulatory. The dogs were classified as acute (n = 27), chronic (n = 72), or unknown (n = 1). Fifty‐four dogs had at least one comorbidity thought to predispose to ATh, and 23 others had multiple comorbidities. The remaining 23 dogs with no obvious comorbidities were classified as cryptogenic. Concurrent illnesses potentially related to the development of ATh included protein‐losing nephropathy (PLN) (n = 32), neoplasia (n = 22), exogenous corticosteroid administration (n = 16), endocrine disease (n = 13), and infection (n = 9). Dogs with PLN had lower antithrombin activity than those without PLN (64% and 82%, respectively) (P = .04). Sixty‐five dogs were hospitalized with 41 subsequently discharged. Sixteen were treated as outpatient and 19 euthanized at admission. In‐hospital treatments varied, but included thrombolytics (n = 12), alone or in combination with thrombectomy (n = 9). Fifty‐seven dogs survived to discharge. Sixteen were alive at 180 days. Using regression analysis, ambulation status at the time of presentation was significantly correlated with survival‐to‐discharge (P < .001). CONCLUSIONS/CLINICAL IMPORTANCE: Dogs with ATh have a poor prognosis, with nonambulatory dogs at the time of presentation having worse outcome. Although the presence of comorbid conditions associated with hypercoagulability is common, an underlying cause for ATh was not always identified.
    Keywords adrenal cortex hormones ; comorbidity ; kidney diseases ; necropsy ; neoplasms ; prognosis ; regression analysis ; retrospective studies ; thrombosis ; ultrasonography ; veterinary medicine
    Language English
    Dates of publication 2020-09
    Size p. 1759-1767.
    Publishing place John Wiley & Sons, Inc.
    Document type Article
    Note NAL-AP-2-clean ; JOURNAL ARTICLE
    ZDB-ID 92798-3
    ISSN 1939-1676 ; 0891-6640
    ISSN (online) 1939-1676
    ISSN 0891-6640
    DOI 10.1111/jvim.15874
    Database NAL-Catalogue (AGRICOLA)

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4095: Show issues Location:
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