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  1. AU="Couture, Marianne"
  2. AU="Ghrab, Jamila"
  3. AU="Bahramizadeh, Mahmood"
  4. AU="Ysmail-Dahlouk, Salim"
  5. AU=Kambara Hiroto
  6. AU="Khamassi, Mehdi"
  7. AU="Green, A"
  8. AU="Cai, Mengting"
  9. AU="Virdi, Annalucia"
  10. AU="Martínez-Taboas, Alfonso"
  11. AU="Yakhou-Harris, F"
  12. AU="Löffler, Bernd"
  13. AU="Kawamura, Michihiro"
  14. AU="Reinius, Björn"
  15. AU="Reis, L C"
  16. AU=Bonsignore M R
  17. AU="Millard, Glenda M"
  18. AU="Springer, Andrea"
  19. AU="Hyunho Han"
  20. AU="Grommen, Sylvia V H"
  21. AU="Asemani, Yahya"
  22. AU="Ketomäki, Tuomo"
  23. AU=Cavallini Giorgio
  24. AU="Saha, Aakash"
  25. AU="Noguchi, J"
  26. AU="Löhr, B."
  27. AU="Lokie, Kelsey B"

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  1. Artikel ; Online: The impact of cognitive interventions on cognitive symptoms in idiopathic Parkinson's disease: a systematic review.

    Couture, Marianne / Giguère-Rancourt, Ariane / Simard, Martine

    Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition

    2018  Band 26, Heft 5, Seite(n) 637–659

    Abstract: This systematic review addressed efficacy of cognitive stimulation (CS), cognitive training (CT), and cognitive rehabilitation (CR) to improve cognitive functions in Parkinson's disease (PD) with (PD-MCI) and without mild cognitive impairment (PD-H). ... ...

    Abstract This systematic review addressed efficacy of cognitive stimulation (CS), cognitive training (CT), and cognitive rehabilitation (CR) to improve cognitive functions in Parkinson's disease (PD) with (PD-MCI) and without mild cognitive impairment (PD-H). Five databases were searched. Twelve CT, four CS, and a combination of CT with CR were found. PD-H benefited from CT or CS compared to active or passive controls in 42.1% of cognitive tests, and in 33.3% of psychological and functional measures. PD-MCI alone, compared with controls, only improved in 6.9% of cognitive measures after CT. PD-H and PD-MCI, alone or together, somehow improved information processing speed, attention, working memory, executive functions, and visual episodic memory. PD-MCI improved better than PD-H in global cognition and planning abilities. The outcomes suggest some efficacy of cognitive interventions in PD. However, small samples, lack of information regarding standardization of interventions, and poor methodological quality limit results validity and prevent firm conclusions.
    Mesh-Begriff(e) Cognitive Dysfunction/etiology ; Cognitive Dysfunction/therapy ; Cognitive Remediation ; Humans ; Outcome Assessment, Health Care ; Parkinson Disease/complications ; Parkinson Disease/therapy
    Sprache Englisch
    Erscheinungsdatum 2018-09-17
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Systematic Review
    ZDB-ID 1482447-4
    ISSN 1744-4128 ; 1382-5585
    ISSN (online) 1744-4128
    ISSN 1382-5585
    DOI 10.1080/13825585.2018.1513450
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Goal management training and psychoeducation / mindfulness for treatment of executive dysfunction in Parkinson's disease: A feasibility pilot trial.

    Giguère-Rancourt, Ariane / Plourde, Marika / Racine, Eva / Couture, Marianne / Langlois, Mélanie / Dupré, Nicolas / Simard, Martine

    PloS one

    2022  Band 17, Heft 2, Seite(n) e0263108

    Abstract: Introduction: As there is currently no pharmacological treatment for Parkinson's Disease Mild Cognitive Impairment (PD-MCI) with executive dysfunctions, specific cognitive interventions must be investigated. Most previous studies have tested bottom-up ... ...

    Abstract Introduction: As there is currently no pharmacological treatment for Parkinson's Disease Mild Cognitive Impairment (PD-MCI) with executive dysfunctions, specific cognitive interventions must be investigated. Most previous studies have tested bottom-up cognitive training programs but have not shown very good results.
    Objectives: The aim of this study was to test ease of implementation, differential safety and preliminary efficacy of two top-down (strategy-learning) home-based, individualized, cognitive interventions: Goal Management Training (GMT), adapted for PD-MCI (Adapted-GMT), and a psychoeducation program combined with mindfulness exercises (PSYCH-Mind).
    Methods: This was a single-blind block-randomized between-group comparative study. Twelve PD-MCI with mild executive dysfunctions were divided in four blocks and randomly assigned to any of the two interventions. The participants were included if they had PD-MCI diagnosis (no dementia), with stabilized medication. Both groups (Adapted-GMT and PSYCH-mind) received five intervention sessions each lasting 60-90 minutes for five weeks. Measures were collected at baseline, mid-point, one-week, four-week and 12-week follow-ups. Executive functions were assessed with the Dysexecutive questionnaire (DEX) and the Zoo Map Test (ZMT). Quality of life (QoL) and psychiatric symptoms were also evaluated. Repeated measures ANCOVAs (mixed linear analysis) were applied to all outcomes.
    Results: There was one drop out, and both interventions were feasible and acceptable. Despite the small sample size limiting statistical power, patients of both groups significantly improved executive functions per the DEX-patient (Time: F(4,36) = 2.96, p = 0.033, CI95%: 10.75-15.23) and DEX-caregiver scores (Time: F(4,36) = 6.02, p = 0.017, CI95%: 9.63-17.23). Both groups significantly made fewer errors between measurement times on the ZMT (Time: F(3,36) = 16.66, p = 0.001, CI95%: 1.07-2.93). However, QoL significantly increased only in PSYCH-Mind patients at four-week follow-up (interaction Time*Group: F(4,36) = 5.31, p = 0.002, CI95%: 15.33-25.61).
    Conclusion: Both interventions were easily implemented and proved to be safe. Because both interventions are arguably cost-effective, these pilot findings, although promising, need to be replicated in large samples.
    Clinicaltrials.gov identifier: NCT04636541.
    Mesh-Begriff(e) Aged ; Caregivers ; Cognitive Dysfunction/complications ; Cognitive Dysfunction/physiopathology ; Cognitive Dysfunction/therapy ; Executive Function ; Feasibility Studies ; Female ; Follow-Up Studies ; Goals ; Humans ; Male ; Middle Aged ; Mindfulness/methods ; Parkinson Disease/complications ; Parkinson Disease/physiopathology ; Parkinson Disease/therapy ; Pilot Projects ; Psychosocial Support Systems ; Quality of Life ; Random Allocation ; Self Report ; Single-Blind Method ; Treatment Outcome
    Sprache Englisch
    Erscheinungsdatum 2022-02-18
    Erscheinungsland United States
    Dokumenttyp Clinical Trial ; Comparative Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0263108
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel: Altered Theory of Mind in Parkinson's Disease and Impact on Caregivers: A Pilot Study.

    Giguère-Rancourt, Ariane / Plourde, Marika / Racine, Eva / Couture, Marianne / Langlois, Mélanie / Dupré, Nicolas / Simard, Martine

    The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques

    2021  Band 49, Heft 3, Seite(n) 437–440

    Abstract: Mild cognitive impairment (MCI) in Parkinson's disease (PD) includes deficits in theory of mind (ToM). However, associations between ToM and caregiver burden and distress are still unclear. The objective of this pilot study was to preliminarily explore ... ...

    Abstract Mild cognitive impairment (MCI) in Parkinson's disease (PD) includes deficits in theory of mind (ToM). However, associations between ToM and caregiver burden and distress are still unclear. The objective of this pilot study was to preliminarily explore the relation between ToM and caregiver burden and distress in a sample of PD-MCI patients. Twelve PD-MCI patients were evaluated on a ToM task (Faux Pas), whereas their caregivers were assessed on caregiver burden (Zarit Burden Interview-12 items) and distress (Neuropsychiatric Inventory-Distress). Cognitive ToM was significantly associated with caregiver distress, but caregiver burden was associated with the severity of patient psychiatric symptoms.
    Mesh-Begriff(e) Caregivers/psychology ; Cognitive Dysfunction/etiology ; Cost of Illness ; Humans ; Parkinson Disease/psychology ; Pilot Projects ; Theory of Mind
    Sprache Englisch
    Erscheinungsdatum 2021-05-14
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 197622-9
    ISSN 0317-1671
    ISSN 0317-1671
    DOI 10.1017/cjn.2021.110
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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