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  1. Book: Dyslipidemias in kidney disease

    Covic, Adrian

    2014  

    Author's details Adrian Covic ... ed
    Keywords Kidneys/Diseases ; Hyperlipidemia
    Subject code 616.61
    Language English
    Size XXI, 312 S. : Ill., graph. Darst., 24 cm
    Publisher Springer
    Publishing place New York u.a.
    Publishing country United States
    Document type Book
    Note Includes bibliographical references
    HBZ-ID HT018273338
    ISBN 978-1-4939-0514-0 ; 9781493905157 ; 1-4939-0514-7 ; 1493905155
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Online ; E-Book: Parathyroid Glands in Chronic Kidney Disease

    Covic, Adrian / Goldsmith, David / Ureña Torres, Pablo A.

    2020  

    Abstract: This concise book provides practical strategies to help nephrologists and endocrinologists correctly diagnose and treat the various forms of parathyroid disease they may encounter in the management of chronic kidney disease. Each chapter deals with ... ...

    Author's details edited by Adrian Covic, David Goldsmith, Pablo A. Ureña Torres
    Abstract This concise book provides practical strategies to help nephrologists and endocrinologists correctly diagnose and treat the various forms of parathyroid disease they may encounter in the management of chronic kidney disease. Each chapter deals with various topics related to parathyroid gland anatomy and physiology, as well as diagnostic tests and their particularities in regard to chronic disease. The book highlights the range of therapies used for the treatment of secondary hyperparathyroidism, and critically analyses the latest research in the field. Providing an up-to-date review of the current literature, including innovations in both medical and surgical treatment and current indications for parathyroidectomy, this practice-oriented book is an excellent resource for nephrologists, endocrinologists, endocrine surgeons and family medicine physicians.
    Keywords Medicine ; Nephrology ; Medicine/Public Health, general
    Subject code 616.61
    Language English
    Size 1 online resource (VI, 196 p. 21 illus., 18 illus. in color.)
    Edition 1st ed. 2020.
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-43769-8 ; 3-030-43768-X ; 978-3-030-43769-5 ; 978-3-030-43768-8
    DOI 10.1007/978-3-030-43769-5
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Book: Cardio-renal clinical challenges

    Goldsmith, David / Covic, Adrian / Spaak, Jonas

    2015  

    Author's details David Goldsmith ; Adrian Covic ; Jonas Spaak ed
    Language English
    Size XIII, 234 S. : Ill., graph. Darst.
    Publisher Springer
    Publishing place Cham u.a.
    Publishing country Switzerland
    Document type Book
    Note Includes bibliographical references
    HBZ-ID HT018515940
    ISBN 978-3-319-09161-7 ; 3-319-09161-1 ; 9783319091624 ; 331909162X
    Database Catalogue ZB MED Medicine, Health

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  4. Article ; Online: Denosumab in the treatment of osteoporosis associated with chronic kidney disease.

    Covic, Adrian / Apetrii, Mugurel

    The lancet. Diabetes & endocrinology

    2024  Volume 12, Issue 4, Page(s) 225–227

    MeSH term(s) Humans ; Denosumab/therapeutic use ; Osteoporosis/complications ; Osteoporosis/drug therapy ; Bone Density Conservation Agents/therapeutic use ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/drug therapy ; Bone Density
    Chemical Substances Denosumab (4EQZ6YO2HI) ; Bone Density Conservation Agents
    Language English
    Publishing date 2024-02-16
    Publishing country England
    Document type Journal Article
    ISSN 2213-8595
    ISSN (online) 2213-8595
    DOI 10.1016/S2213-8587(24)00057-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Book ; Online ; E-Book: Clinical nephrogeriatrics

    Musso, Carlos Guido / Jauregui, José Ricardo / Macías-Núñez, Juan Florencio / Covic, Adrian

    an evidence-based guide

    2019  

    Author's details Carlos Guido Musso, José Ricardo Jauregui, Juan Florencio Macías-Núñez, Adrian Covic editors
    Keywords Electronic books
    Language English
    Size 1 Online-Ressource (xiii, 265 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT020187221
    ISBN 978-3-030-18711-8 ; 9783030187101 ; 3-030-18711-X ; 3030187101
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  6. Article: Special Issue: "Cardiovascular Complications in Renal Diseases".

    Burlacu, Alexandru / Covic, Adrian

    Journal of clinical medicine

    2023  Volume 12, Issue 16

    Abstract: The intricate interplay between cardiovascular (CV) pathology and chronic kidney disease (CKD) encompasses diagnostic protocols (both clinical and paraclinical), outcome assessments (such as mortality, morbidity, and costs), as well as advancements in ... ...

    Abstract The intricate interplay between cardiovascular (CV) pathology and chronic kidney disease (CKD) encompasses diagnostic protocols (both clinical and paraclinical), outcome assessments (such as mortality, morbidity, and costs), as well as advancements in new therapeutic approaches (including pharmacological, interventional, and surgical modalities) [...].
    Language English
    Publishing date 2023-08-15
    Publishing country Switzerland
    Document type Editorial
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12165307
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Book ; Online ; E-Book: Resistant hypertension in chronic kidney disease

    Covic, Adrian / Kanbay, Mehmet / Lerma, Edgar V.

    2017  

    Author's details Adrian Covic, Mehmet Kanbay, Edgar V. Lerma editors
    Language English
    Size 1 Online-Ressource (xviii, 365 Seiten), Illustrationen
    Publisher Springer
    Publishing place Cham
    Publishing country Switzerland
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    HBZ-ID HT019536270
    ISBN 978-3-319-56827-0 ; 9783319568256 ; 3-319-56827-2 ; 3319568256
    DOI 10.1007/978-3-319-56827-0
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  8. Article: Vitamin K supplementation impact in dialysis patients: a systematic review and meta-analysis of randomized trials.

    Andrian, Titus / Stefan, Anca / Nistor, Ionut / Covic, Adrian

    Clinical kidney journal

    2023  Volume 16, Issue 12, Page(s) 2738–2749

    Abstract: Vitamin K supplementation has been considered recently as a potential treatment for addressing vascular calcification in chronic kidney disease patients. We conducted a systematic review and meta-analysis to summarize the impact of vitamin K ... ...

    Abstract Vitamin K supplementation has been considered recently as a potential treatment for addressing vascular calcification in chronic kidney disease patients. We conducted a systematic review and meta-analysis to summarize the impact of vitamin K supplementation in dialysis patients. Electronic databases were searched for clinical randomized trials among patients treated with vitamin K. Random effects models were performed and risk of bias was evaluated with Cochrane tools and the search was conducted until 15 of September 2023. Eleven trials comprising 830 patients (both adult and pediatric, mainly hemodialysis) compared vitamin K with different controls: lower doses of vitamin K, standard care or placebo. Vitamin K supplementation had no effect on mortality. Vitamin K administration improved vitamin K levels and led to lower levels of dp-uc-MGP and moderately increased calcium levels [0.18 (0.04-0.32)]. Vitamin K1 proved more potency in reducing dp-uc-MGP [SMD -1.64 (-2.05, -1.23) vs. -0.56 (-0.82, -0.31)] and also raised serum vitamin K levels in comparison with vitamin K2 [5.69 (3.43, 7.94) vs. 2.25 (-2.36, 6.87)]. While it did not have a proved benefit in changing calcification scores [-0.14 (-0.37 ± 0.09)], vitamin K proved to be a safe product. There was some concern with bias. Vitamin K supplementation has no impact on mortality and did not show significant benefit in reversing calcification scores. Vitamin K1 improved vitamin K deposits and lowered dp-uc-MGP, which is a calcification biomarker more than vitamin K2. As it proved to be a safe product, additional randomized well-powered studies with improved treatment regimens are needed to establish the true impact of vitamin K in dialysis patients.
    Language English
    Publishing date 2023-10-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfad255
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: A review on renal autologous cell transplantation: an investigational approach towards chronic kidney disease.

    Copur, Sidar / Yavuz, Furkan / Covic, Adrian / Kanbay, Mehmet

    International urology and nephrology

    2023  Volume 55, Issue 10, Page(s) 2539–2544

    Abstract: Chronic kidney disease is among the most common causes of mortality and morbidity in adult population with limited therapeutic approaches including various medications and kidney replacement therapies. Kidney transplantation is the gold standard ... ...

    Abstract Chronic kidney disease is among the most common causes of mortality and morbidity in adult population with limited therapeutic approaches including various medications and kidney replacement therapies. Kidney transplantation is the gold standard therapeutic alternative for the management of chronic kidney disease; nonetheless, important drawbacks include the lack of adequate living or deceased donors, high rates of pre- and post-operative complications including surgical complications, infectious complications and medication-induced adverse effects. With the latest preclinical and in vitro studies demonstrating the potentiality of kidney cells obtained from diseased kidneys to convert into fully functional kidney cells lead to a novel therapeutic alternative referred as autologous selected renal cell transplantation. Even though the clinical studies investigating the efficiency and adverse effects of autologous selected renal cell transplantation are limited, it is no doubt promising. The need for future large-scale studies on chronic kidney disease patients from a diversity of etiologies is clear for the better establishment of the therapeutic potential of autologous selected renal cell transplantation. In this narrative review, our aim is to evaluate the role of renal autologous stem cell therapy in the management of chronic kidney disease.
    MeSH term(s) Adult ; Humans ; Kidney Transplantation/adverse effects ; Kidney ; Renal Insufficiency, Chronic ; Tissue Donors ; Transplantation, Autologous ; Cell Transplantation
    Language English
    Publishing date 2023-03-27
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 204048-7
    ISSN 1573-2584 ; 0301-1623 ; 0042-1162
    ISSN (online) 1573-2584
    ISSN 0301-1623 ; 0042-1162
    DOI 10.1007/s11255-023-03574-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Efficacy and Safety of Ticagrelor versus Clopidogrel in Dialysis Patients with Coronary Syndromes: A Systematic Review and Meta-Analysis.

    Burlacu, Alexandru / Floria, Mariana / Brinza, Crischentian / Covic, Adrian

    Journal of clinical medicine

    2023  Volume 12, Issue 15

    Abstract: 1) Background: The optimal antiplatelet therapy for end-stage kidney disease (ESKD) patients on chronic dialysis presenting with acute or chronic coronary syndromes (ACS or CCS) remains uncertain. This meta-analysis aimed to compare the efficacy and ... ...

    Abstract (1) Background: The optimal antiplatelet therapy for end-stage kidney disease (ESKD) patients on chronic dialysis presenting with acute or chronic coronary syndromes (ACS or CCS) remains uncertain. This meta-analysis aimed to compare the efficacy and safety endpoints of ticagrelor and clopidogrel in ESKD patients requiring dialysis and presenting with ACS or CCS. (2) Methods: Studies were included comparing ticagrelor and clopidogrel in ESKD patients on chronic dialysis with ACS or CCS. The primary composite efficacy outcome was a combination of all-cause and cardiovascular mortality, recurrent myocardial infarction or coronary revascularization, and ischemic or hemorrhagic stroke. The primary safety outcome was major and non-major bleeding events. (3) Results: Five observational studies met the eligibility criteria. The pooled analysis showed no significant difference in the primary composite efficacy outcome between ticagrelor and clopidogrel (
    Language English
    Publishing date 2023-07-30
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12155011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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