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  1. Article ; Online: Growth hormone supplementation in women who are not poor responders.

    Cozzolino, Mauro

    Journal of assisted reproduction and genetics

    2021  Volume 38, Issue 5, Page(s) 1261–1262

    MeSH term(s) Dietary Supplements ; Female ; Human Growth Hormone ; Humans ; Infertility ; Oocytes/drug effects ; Pregnancy ; Pregnancy Rate
    Chemical Substances Human Growth Hormone (12629-01-5)
    Language English
    Publishing date 2021-03-27
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1112577-9
    ISSN 1573-7330 ; 1058-0468
    ISSN (online) 1573-7330
    ISSN 1058-0468
    DOI 10.1007/s10815-021-02166-5
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    Zs.A 1985: Show issues Location:
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  2. Article ; Online: Recurrent implantation failure might be overestimated without PGT-A.

    Cozzolino, Mauro

    Archives of gynecology and obstetrics

    2020  Volume 304, Issue 3, Page(s) 849–850

    MeSH term(s) Embryo Implantation ; Female ; Humans ; Pregnancy ; Preimplantation Diagnosis
    Language English
    Publishing date 2020-09-01
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 896455-5
    ISSN 1432-0711 ; 0932-0067
    ISSN (online) 1432-0711
    ISSN 0932-0067
    DOI 10.1007/s00404-020-05775-0
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  3. Article ; Online: Is it realistic to consider vitamin D as a follicular and serum marker of human oocyte quality?

    Cozzolino, Mauro

    Journal of assisted reproduction and genetics

    2018  Volume 36, Issue 1, Page(s) 173–174

    MeSH term(s) Biomarkers/blood ; Female ; Fertilization in Vitro ; Follicular Fluid/metabolism ; Humans ; Live Birth ; Oocytes/cytology ; Oocytes/metabolism ; Pregnancy ; Pregnancy Rate ; Vitamin D/blood ; Vitamins/blood
    Chemical Substances Biomarkers ; Vitamins ; Vitamin D (1406-16-2)
    Language English
    Publishing date 2018-10-27
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 1112577-9
    ISSN 1573-7330 ; 1058-0468
    ISSN (online) 1573-7330
    ISSN 1058-0468
    DOI 10.1007/s10815-018-1351-x
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    Zs.A 1985: Show issues Location:
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  4. Article: The Wnt/β-catenin signaling: a multifunctional target for neuroprotective and regenerative strategies in Parkinson's disease.

    Serafino, Annalucia / Cozzolino, Mauro

    Neural regeneration research

    2022  Volume 18, Issue 2, Page(s) 306–308

    Language English
    Publishing date 2022-08-24
    Publishing country India
    Document type Journal Article
    ZDB-ID 2388460-5
    ISSN 1876-7958 ; 1673-5374
    ISSN (online) 1876-7958
    ISSN 1673-5374
    DOI 10.4103/1673-5374.343908
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  5. Article ; Online: Mitochondrial dysfunction caused by targeted deletion of

    Cozzolino, Mauro / Seli, Emre

    Zygote (Cambridge, England)

    2022  Volume 30, Issue 5, Page(s) 735–737

    Abstract: Telomere shortening during oocyte growth and development is related to reproductive ageing and infertility. The main mechanism involved in the maintenance of telomeres is based on telomerase activity, a specialized enzyme complex, which is capable of ... ...

    Abstract Telomere shortening during oocyte growth and development is related to reproductive ageing and infertility. The main mechanism involved in the maintenance of telomeres is based on telomerase activity, a specialized enzyme complex, which is capable of adding TTAGGG repeats at the ends of the chromosomes. Mitochondrial dysfunction may cause progressive shortening of telomeres by promoting the generation of reactive oxygen species. Mitofusin-1 is a protein required for mitochondrial fusion. Mice with the mitofusin-1 (
    MeSH term(s) Animals ; GTP Phosphohydrolases/genetics ; GTP Phosphohydrolases/metabolism ; Infertility ; Mice ; Mitochondria/metabolism ; Oocytes/physiology ; Reactive Oxygen Species/metabolism ; Telomerase/genetics ; Telomerase/metabolism ; Telomere/genetics ; Telomere/metabolism ; Telomere Shortening
    Chemical Substances Reactive Oxygen Species ; Telomerase (EC 2.7.7.49) ; GTP Phosphohydrolases (EC 3.6.1.-) ; Mfn1 protein, mouse (EC 3.6.1.-)
    Language English
    Publishing date 2022-06-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 1166294-3
    ISSN 1469-8730 ; 0967-1994
    ISSN (online) 1469-8730
    ISSN 0967-1994
    DOI 10.1017/S0967199422000089
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  6. Article: Oocyte Cryopreservation in Women with Ovarian Endometriosis.

    Mifsud, Judith-Marie / Pellegrini, Livia / Cozzolino, Mauro

    Journal of clinical medicine

    2023  Volume 12, Issue 21

    Abstract: Ovarian endometriosis is a gynecological condition that is closely associated with infertility-from its pathogenesis to treatment modalities, this condition presents a challenge both for patients and clinicians alike when seeking conception, due to low ... ...

    Abstract Ovarian endometriosis is a gynecological condition that is closely associated with infertility-from its pathogenesis to treatment modalities, this condition presents a challenge both for patients and clinicians alike when seeking conception, due to low AMH levels, peritoneal inflammation, and the inadvertent removal of healthy ovarian parenchyma at surgery. In fact, around half of endometriosis patients seeking fertility require tertiary-level assisted reproduction techniques to achieve a live birth. Oocyte cryopreservation, a procedure initially designed for oncology patients, has emerged over recent years as a very promising treatment strategy for patients who have been diagnosed with ovarian endometriosis in order to preserve their fertility and obtain a live birth at a later stage in their lives. Counseling patients about oocyte preservation techniques at an early stage in the diagnosis, ideally before the age of 35 and especially prior to any surgical treatment, provides an excellent opportunity to discuss future fertility and the benefits associated with oocyte cryopreservation.
    Language English
    Publishing date 2023-10-26
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm12216767
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  7. Article ; Online: Vitamin D Levels Do Not Affect Natural Fertility and in vitro Fertilization Outcomes.

    Cozzolino, Mauro

    Gynecologic and obstetric investigation

    2017  Volume 82, Issue 3, Page(s) 311–312

    MeSH term(s) Fertility ; Fertilization in Vitro ; Vitamin D
    Chemical Substances Vitamin D (1406-16-2)
    Language English
    Publishing date 2017
    Publishing country Switzerland
    Document type Journal Article ; Comment
    ZDB-ID 800003-7
    ISSN 1423-002X ; 0378-7346
    ISSN (online) 1423-002X
    ISSN 0378-7346
    DOI 10.1159/000468936
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    Zs.A 688: Show issues Location:
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  8. Article ; Online: Local intraendometrial estrogen biosynthesis leading to progesterone resistance impacts implantation in adenomyosis and endometriosis.

    Humaidan, Peter / Garcia Velasco, Juan Antonio / Cozzolino, Mauro

    Fertility and sterility

    2023  Volume 120, Issue 4, Page(s) 927

    MeSH term(s) Female ; Humans ; Endometriosis ; Adenomyosis/drug therapy ; Adenomyosis/surgery ; Uterine Diseases ; Estrogens ; Progesterone
    Chemical Substances Estrogens ; Progesterone (4G7DS2Q64Y)
    Language English
    Publishing date 2023-06-07
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80133-1
    ISSN 1556-5653 ; 0015-0282
    ISSN (online) 1556-5653
    ISSN 0015-0282
    DOI 10.1016/j.fertnstert.2023.06.004
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  9. Article ; Online: Dysfunction of RNA/RNA-Binding Proteins in ALS Astrocytes and Microglia.

    Rossi, Simona / Cozzolino, Mauro

    Cells

    2021  Volume 10, Issue 11

    Abstract: Amyotrophic Lateral Sclerosis is a neurological disease that primarily affects motor neurons in the cortex, brainstem, and spinal cord. The process that leads to motor neuron degeneration is strongly influenced by non-motor neuronal events that occur in ... ...

    Abstract Amyotrophic Lateral Sclerosis is a neurological disease that primarily affects motor neurons in the cortex, brainstem, and spinal cord. The process that leads to motor neuron degeneration is strongly influenced by non-motor neuronal events that occur in a variety of cell types. Among these, neuroinflammatory processes mediated by activated astrocytes and microglia play a relevant role. In recent years, it has become clear that dysregulation of essential steps of RNA metabolism, as a consequence of alterations in RNA-binding proteins (RBPs), is a central event in the degeneration of motor neurons. Yet, a causal link between dysfunctional RNA metabolism and the neuroinflammatory processes mediated by astrocytes and microglia in ALS has been poorly defined. In this review, we will discuss the available evidence showing that RBPs and associated RNA processing are affected in ALS astrocytes and microglia, and the possible mechanisms involved in these events.
    MeSH term(s) Amyotrophic Lateral Sclerosis/metabolism ; Amyotrophic Lateral Sclerosis/pathology ; Animals ; Astrocytes/metabolism ; Astrocytes/pathology ; Humans ; Inflammation/pathology ; Microglia/metabolism ; Microglia/pathology ; Neurons/metabolism ; Neurons/pathology ; RNA-Binding Proteins/metabolism
    Chemical Substances RNA-Binding Proteins
    Language English
    Publishing date 2021-11-03
    Publishing country Switzerland
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells10113005
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  10. Article ; Online: The psychosocial genomics paradigm of hypnosis and mind-body integrated psychotherapy: Experimental evidence.

    Cozzolino, Mauro / Celia, Giovanna

    The American journal of clinical hypnosis

    2021  Volume 64, Issue 2, Page(s) 123–138

    Abstract: The psychosocial genomics paradigm first proposed by Ernest Rossi established an epistemological shift in our application of hypnosis. We present original experimental research conducted within this paradigm that highlights the mind-gene relationship and, ...

    Abstract The psychosocial genomics paradigm first proposed by Ernest Rossi established an epistemological shift in our application of hypnosis. We present original experimental research conducted within this paradigm that highlights the mind-gene relationship and, in particular, the positive health effects associated with hypnosis and mind-body integrated psychotherapy. We document that these approaches can stimulate epigenetic modifications and the expression of genes related to anti-inflammatory processes. These strategies strengthen the immune system and reduce oxidative stress both in normal and in oncological participants.
    MeSH term(s) Genomics ; Humans ; Hypnosis ; Psychotherapy
    Language English
    Publishing date 2021-11-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 219387-5
    ISSN 2160-0562 ; 0002-9157
    ISSN (online) 2160-0562
    ISSN 0002-9157
    DOI 10.1080/00029157.2021.1947767
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