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  1. Article ; Online: Author Q&A: Grant Creaney.

    Creaney, Grant

    British dental journal

    2023  Volume 234, Issue 1, Page(s) 40

    Language English
    Publishing date 2023-01-13
    Publishing country England
    Document type News
    ZDB-ID 218090-x
    ISSN 1476-5373 ; 0007-0610
    ISSN (online) 1476-5373
    ISSN 0007-0610
    DOI 10.1038/s41415-023-5437-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Reviewing the epidemiology of head and neck cancer: definitions, trends and risk factors.

    Gormley, Mark / Creaney, Grant / Schache, Andrew / Ingarfield, Kate / Conway, David I

    British dental journal

    2022  Volume 233, Issue 9, Page(s) 780–786

    Abstract: Introduction Head and neck cancer appears to be increasing in incidence, with potential changes in aetiology proposed. This paper aims to provide a narrative overview of the epidemiological literature to describe the disease burden and trends in terms of ...

    Abstract Introduction Head and neck cancer appears to be increasing in incidence, with potential changes in aetiology proposed. This paper aims to provide a narrative overview of the epidemiological literature to describe the disease burden and trends in terms of incidence and mortality both in the UK and globally and to review the evidence on current risk factors.Methods A search was performed on multiple databases (PubMed and Epistemonikos), applying filters to identify systematic reviews and meta-analyses which investigated head and neck cancer incidence, mortality and risk factors. International and UK cancer registries and sources were searched for incidence and mortality data.Results Multiple definitions of head and neck cancer are employed in epidemiology. Globally, incidence rates have increased in recent decades, largely driven by oropharyngeal cancer. Mortality rates over the last decade have also started to rise, reflecting the disease incidence and static survival rates. Major risk factors include tobacco smoking alone and in combination with alcohol consumption, betel chewing (particularly in Southeast Asian populations) and the human papillomavirus in oropharyngeal cancer.Conclusions These epidemiological data can inform clinical and preventive service planning for head and neck cancer.
    MeSH term(s) Humans ; Head and Neck Neoplasms/epidemiology ; Head and Neck Neoplasms/etiology ; Oropharyngeal Neoplasms/epidemiology ; Risk Factors ; Papillomaviridae ; Incidence ; Papillomavirus Infections/complications ; Papillomavirus Infections/epidemiology
    Language English
    Publishing date 2022-11-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 218090-x
    ISSN 1476-5373 ; 0007-0610
    ISSN (online) 1476-5373
    ISSN 0007-0610
    DOI 10.1038/s41415-022-5166-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Head and neck cancer in the UK: what was the stage before COVID-19? UK cancer registries analysis (2011-2018).

    Creaney, Grant / McMahon, Alex D / Ross, Alastair J / Bhatti, Lesley A / Paterson, Claire / Conway, David I

    British dental journal

    2022  Volume 233, Issue 9, Page(s) 787–793

    Abstract: Introduction People who present with more advanced stage head and neck cancer (HNC) are associated with poorer outcomes and survival. The burden and trends of advanced stage HNC are not fully known at the population level. The UK national cancer ... ...

    Abstract Introduction People who present with more advanced stage head and neck cancer (HNC) are associated with poorer outcomes and survival. The burden and trends of advanced stage HNC are not fully known at the population level. The UK national cancer registries routinely collect data on HNC diagnoses.Aims To describe trends in stage of diagnosis of HNCs across the UK before the COVID-19 pandemic.Methods Aggregated HNC incidence data were requested from the national cancer registries of the four UK countries for the ten most recent years of available data by subsite and American Joint Commission on Cancer stage at diagnosis classification. Additionally, data for Scotland were available by age group, sex and area-based socioeconomic deprivation category.Results Across the UK, rates of advanced stage HNC had increased, with 59% of patients having advanced disease at diagnosis from 2016-2018. England had a lower proportion of advanced disease (58%) than Scotland, Wales or Northern Ireland (65-69%) where stage data were available. The completeness of stage data had improved over recent years (87% by 2018).Conclusion Prior to the COVID-19 pandemic, diagnoses of HNC at an advanced stage comprised the majority of HNCs in the UK, representing the major challenge for the cancer healthcare system.
    MeSH term(s) Humans ; United States ; COVID-19/epidemiology ; Pandemics ; Head and Neck Neoplasms/epidemiology ; Registries ; Incidence ; England/epidemiology
    Language English
    Publishing date 2022-11-11
    Publishing country England
    Document type Journal Article
    ZDB-ID 218090-x
    ISSN 1476-5373 ; 0007-0610
    ISSN (online) 1476-5373
    ISSN 0007-0610
    DOI 10.1038/s41415-022-5151-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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