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  1. Article: Acute Toxicity and Pharmacokinetic Profile of an EU-GMP-Certified

    Filipiuc, Leontina-Elena / Ştefănescu, Raluca / Solcan, Carmen / Ciorpac, Mitică / Szilagyi, Andrei / Cojocaru, Dana / Stanciu, Gabriela Dumitrita / Creangă, Ioana / Caratașu, Cătălin-Cezar / Ababei, Daniela-Carmen / Gavrila, Roxana-Elena / Timofte, Andrei-Daniel / Filipiuc, Silviu-Iulian / Bild, Veronica

    Pharmaceuticals (Basel, Switzerland)

    2023  Volume 16, Issue 5

    Abstract: The conundrum ... ...

    Abstract The conundrum of
    Language English
    Publishing date 2023-05-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2193542-7
    ISSN 1424-8247
    ISSN 1424-8247
    DOI 10.3390/ph16050694
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: The Therapeutic Potential of the Endocannabinoid System in Age-Related Diseases.

    Tudorancea, Ivona Maria / Ciorpac, Mitică / Stanciu, Gabriela Dumitrița / Caratașu, Cătălin / Săcărescu, Alina / Ignat, Bogdan / Burlui, Alexandra / Rezuș, Elena / Creangă, Ioana / Alexa-Stratulat, Teodora / Tudorancea, Ionuț / Tamba, Bogdan Ionel

    Biomedicines

    2022  Volume 10, Issue 10

    Abstract: The endocannabinoid system (ECS) dynamically regulates many aspects of mammalian physiology. ECS has gained substantial interest since growing evidence suggests that it also plays a major role in several pathophysiological conditions due to its ability ... ...

    Abstract The endocannabinoid system (ECS) dynamically regulates many aspects of mammalian physiology. ECS has gained substantial interest since growing evidence suggests that it also plays a major role in several pathophysiological conditions due to its ability to modulate various underlying mechanisms. Furthermore, cannabinoids, as components of the cannabinoid system (CS), have proven beneficial effects such as anti-inflammatory, immunomodulatory, neuromodulatory, antioxidative, and cardioprotective effects. In this comprehensive review, we aimed to describe the complex interaction between CS and most common age-related diseases such as neuro-degenerative, oncological, skeletal, and cardiovascular disorders, together with the potential of various cannabinoids to ameliorate the progression of these disorders. Since chronic inflammation is postulated as the pillar of all the above-mentioned medical conditions, we also discuss in this paper the potential of CS to ameliorate aging-associated immune system dysregulation.
    Language English
    Publishing date 2022-10-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines10102492
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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