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Artikel ; Online: Non-toxigenic tox gene-bearing Corynebacterium ulcerans in a traumatic ulcer from a human case and his asymptomatic dog.

Fuursted, Kurt / Søes, Lillian Marie / Crewe, Bjørn Thomas / Stegger, Marc / Andersen, Paal Skytt / Christensen, Jens Jørgen

Microbes and infection

2015  Band 17, Heft 10, Seite(n) 717–719

Abstract: A non-toxigenic tox gene-bearing (NTTB) Corynebacterium ulcerans was grown from the wound of a 61-year-old gardener and in a nasal specimen from the patient's asymptomatic dog. The two isolates were similar in terms of antibiogram, multilocus sequence ... ...

Abstract A non-toxigenic tox gene-bearing (NTTB) Corynebacterium ulcerans was grown from the wound of a 61-year-old gardener and in a nasal specimen from the patient's asymptomatic dog. The two isolates were similar in terms of antibiogram, multilocus sequence typing (ST341), virulence genes, and only three SNPs were found to differentiate the two NTTB C. ulcerans isolates supporting a zoonotic transmission to or between the patient and his dog. Of interest, we found that the two C. ulcerans isolates, although not expressing the diphtheria toxin tox, possessed 13 out of 14 recently described virulence candidate genes.
Mesh-Begriff(e) Animals ; Bacterial Toxins/genetics ; Carrier State/microbiology ; Carrier State/veterinary ; Corynebacterium/classification ; Corynebacterium/drug effects ; Corynebacterium/genetics ; Corynebacterium/isolation & purification ; Corynebacterium Infections/microbiology ; Corynebacterium Infections/pathology ; Corynebacterium Infections/veterinary ; Diphtheria Toxin/genetics ; Dogs ; Humans ; Male ; Microbial Sensitivity Tests ; Middle Aged ; Multilocus Sequence Typing ; Polymorphism, Single Nucleotide ; Ulcer/microbiology ; Ulcer/pathology ; Virulence Factors/genetics ; Wound Infection/microbiology ; Wound Infection/pathology ; Wounds and Injuries/complications ; Zoonoses/microbiology ; Zoonoses/transmission
Chemische Substanzen Bacterial Toxins ; Diphtheria Toxin ; Virulence Factors
Sprache Englisch
Erscheinungsdatum 2015-10
Erscheinungsland France
Dokumenttyp Case Reports ; Journal Article
ZDB-ID 1465093-9
ISSN 1769-714X ; 1286-4579
ISSN (online) 1769-714X
ISSN 1286-4579
DOI 10.1016/j.micinf.2015.07.004
Signatur
Zs.A 5014: Hefte anzeigen Standort:
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