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  1. Book ; Online ; E-Book: Sexually Transmitted Infections

    Cristaudo, Antonio / Giuliani, Massimo

    Advances in Understanding and Management

    2020  

    Abstract: This comprehensive, well-illustrated, and easily accessible book documents the latest research outcomes concerning sexually transmitted infections (STIs) and describes important advances in their prevention, diagnosis and treatment. The changes in the ... ...

    Author's details edited by Antonio Cristaudo, Massimo Giuliani
    Abstract This comprehensive, well-illustrated, and easily accessible book documents the latest research outcomes concerning sexually transmitted infections (STIs) and describes important advances in their prevention, diagnosis and treatment. The changes in the epidemiology and clinical aspects of STIs that have occurred over the past decade are fully explored, with special attention to core groups and patients with immunological disorders. The emerging challenges associated with particular sexually transmitted pathogens, including C. trachomatis, N. gonorrhoeae, HPV, and HIV, are identified and discussed. Readers will find detailed information on modern preventive strategies, new laboratory and diagnostic techniques, and a range of innovative treatments, including vaccines, continuous antiretroviral therapy, and new drugs against hepatitis viruses. Attention is also drawn to new directions in biomedical research that promise clinical benefits for the patients and communities. The combination of a detailed clinical and research approach, with emphasis on new knowledge and innovative aspects, ensures that the book will be of value to a wide readership comprising both clinicians and researchers. .
    Keywords Dermatology ; Infectious diseases ; Epidemiology ; Health promotion ; General practice (Medicine) ; Infectious Diseases ; Health Promotion and Disease Prevention ; General Practice / Family Medicine
    Subject code 616.9
    Language English
    Size 1 online resource (xxxi, 427 pages) :, illustrations
    Edition 1st ed. 2020.
    Publisher Springer International Publishing ; Imprint: Springer
    Publishing place Cham
    Document type Book ; Online ; E-Book
    Remark Zugriff für angemeldete ZB MED-Nutzerinnen und -Nutzer
    ISBN 3-030-02200-5 ; 3-030-02199-8 ; 978-3-030-02200-6 ; 978-3-030-02199-3
    DOI 10.1007/978-3-030-02200-6
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Effectiveness of anti-interleukin 23 biologic drugs in psoriasis patients who failed anti-interleukin 17 regimens. A real-life experience.

    Bonifati, Claudio / Morrone, Aldo / Cristaudo, Antonio / Graceffa, Dario

    Dermatologic therapy

    2020  Volume 34, Issue 1, Page(s) e14584

    Abstract: Among the most recent biologic drugs available for psoriasis therapy, those targeting interleukin-17 (secukinumab and ixekizumab) or its receptor (brodalumab) have been shown to be quickly effective. However, in those patients who failed one or more of ... ...

    Abstract Among the most recent biologic drugs available for psoriasis therapy, those targeting interleukin-17 (secukinumab and ixekizumab) or its receptor (brodalumab) have been shown to be quickly effective. However, in those patients who failed one or more of the above-cited drugs, real-life data on the effectiveness of switching to one anti-interleukin-23 biologic (guselkumab, risankizumab, or tildrakizumab) are very scarce. Here, we report our experience in treating 12 multi-failure psoriatic patients, prospectively followed-up over 6 months, who showed a significant improvement in their psoriasis after switching from an anti-interleukn-17 to an anti-interleukin-23 drug.
    MeSH term(s) Biological Products ; Humans ; Interleukin-17 ; Interleukin-23 ; Psoriasis/diagnosis ; Psoriasis/drug therapy
    Chemical Substances Biological Products ; Interleukin-17 ; Interleukin-23
    Language English
    Publishing date 2020-12-06
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.14584
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    Zs.A 5181: Show issues Location:
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  3. Article ; Online: Allergic Contact Dermatitis, an Important Skin Reaction in Diabetes Device Users: A Systematic Review.

    Cameli, Norma / Silvestri, Martina / Mariano, Maria / Messina, Claudia / Nisticò, Steven Paul / Cristaudo, Antonio

    Dermatitis : contact, atopic, occupational, drug

    2022  Volume 33, Issue 2, Page(s) 110–115

    Abstract: Abstract: Diabetes management has undergone many advances over the years, including the introduction of devices that allow patients to monitor blood glucose and administer insulin. Although these devices have improved patients' quality of life, they are ...

    Abstract Abstract: Diabetes management has undergone many advances over the years, including the introduction of devices that allow patients to monitor blood glucose and administer insulin. Although these devices have improved patients' quality of life, they are associated with adverse reactions.A systematic literature search was performed up to May 2020 in PubMed, Cochrane, and Embase databases, with no temporal restrictions. Articles were screened by title, abstract, and full text as needed. A manual search among the references of the included articles was also performed.Two hundred sixty-five articles were identified, and 50 studies met inclusion criteria. Several cases of allergic contact dermatitis due to the use of insulin infusion systems and blood glucose monitoring have been reported. Acrylates, methacrylates, and colophonium, as well as, in particular, isobornyl acrylate, represent the main allergens responsible.Skin reactions, in particular allergic contact dermatitis, are a very common adverse event caused by insulin pumps and glucose sensors, which may lead to discontinue the usage of these devices with serious consequences for the patients. Collaboration between specialists, specifically between dermatologists and diabetologists, with patients and manufacturers is essential for the correct management of diabetes devices and potential related skin reactions.
    MeSH term(s) Acrylates/adverse effects ; Blood Glucose ; Blood Glucose Self-Monitoring ; Dermatitis, Allergic Contact/etiology ; Diabetes Mellitus ; Humans ; Patch Tests/adverse effects ; Quality of Life
    Chemical Substances Acrylates ; Blood Glucose
    Language English
    Publishing date 2022-03-02
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 2144723-8
    ISSN 2162-5220 ; 1532-8163 ; 1710-3568
    ISSN (online) 2162-5220 ; 1532-8163
    ISSN 1710-3568
    DOI 10.1097/DER.0000000000000861
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3680: Show issues Location:
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  4. Article ; Online: Safety of Interleukin Inhibitors in Patients with Plaque Psoriasis and Neoplasm: A Retrospective Study from Two Referral Centers.

    Gargiulo, Luigi / Ibba, Luciano / Valenti, Mario / Orsini, Diego / Cristaudo, Antonio / Frascione, Pasquale / Costanzo, Antonio / Narcisi, Alessandra

    Clinical drug investigation

    2023  Volume 43, Issue 10, Page(s) 807–812

    Language English
    Publishing date 2023-09-16
    Publishing country New Zealand
    Document type Letter
    ZDB-ID 1220136-4
    ISSN 1179-1918 ; 0114-2402 ; 1173-2563
    ISSN (online) 1179-1918
    ISSN 0114-2402 ; 1173-2563
    DOI 10.1007/s40261-023-01306-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 2807: Show issues Location:
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  5. Article ; Online: Modulating the skin mycobiome-bacteriome and treating seborrheic dermatitis with a probiotic-enriched oily suspension.

    Truglio, Mauro / Sivori, Francesca / Cavallo, Ilaria / Abril, Elva / Licursi, Valerio / Fabrizio, Giorgia / Cardinali, Giorgia / Pignatti, Marco / Toma, Luigi / Valensise, Floriana / Cristaudo, Antonio / Pimpinelli, Fulvia / Di Domenico, Enea Gino

    Scientific reports

    2024  Volume 14, Issue 1, Page(s) 2722

    Abstract: Seborrheic dermatitis (SD) affects 2-5% of the global population, with imbalances in the skin microbiome implicated in its development. This study assessed the impact of an oily suspension containing Lactobacillus crispatus P17631 and Lacticaseibacillus ... ...

    Abstract Seborrheic dermatitis (SD) affects 2-5% of the global population, with imbalances in the skin microbiome implicated in its development. This study assessed the impact of an oily suspension containing Lactobacillus crispatus P17631 and Lacticaseibacillus paracasei I1688 (termed EUTOPLAC) on SD symptoms and the skin mycobiome-bacteriome modulation. 25 SD patients were treated with EUTOPLAC for a week. Symptom severity and skin mycobiome-bacteriome changes were measured at the start of the treatment (T0), after seven days (T8), and three weeks post-treatment (T28). Results indicated symptom improvement post-EUTOPLAC, with notable reductions in the Malassezia genus. Concurrently, bacterial shifts were observed, including a decrease in Staphylococcus and an increase in Lactobacillus and Lacticaseibacillus. Network analysis highlighted post-EUTOPLAC instability in fungal and bacterial interactions, with increased negative correlations between Malassezia and Lactobacillus and Lacticaseibacillus genera. The study suggests EUTOPLAC's potential as a targeted SD treatment, reducing symptoms and modulating the mycobiome-bacteriome composition.
    MeSH term(s) Humans ; Mycobiome ; Dermatitis, Seborrheic/therapy ; Dermatitis, Seborrheic/microbiology ; Skin ; Microbiota ; Bacteria ; Malassezia ; Probiotics/therapeutic use
    Language English
    Publishing date 2024-02-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-024-53016-0
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  6. Article ; Online: Vitamin K

    Cameli, Norma / Zanniello, Ramona / Mariano, Maria / Cristaudo, Antonio

    Contact dermatitis

    2019  Volume 82, Issue 3, Page(s) 189–190

    MeSH term(s) Antineoplastic Agents, Immunological/therapeutic use ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Cetuximab/therapeutic use ; Colorectal Neoplasms/drug therapy ; Dermatitis, Phototoxic/etiology ; Facial Dermatoses/chemically induced ; Female ; Humans ; Middle Aged ; Skin Cream/adverse effects ; Vitamin K 1/adverse effects ; Vitamins/adverse effects
    Chemical Substances Antineoplastic Agents, Immunological ; Vitamins ; Vitamin K 1 (84-80-0) ; Cetuximab (PQX0D8J21J)
    Language English
    Publishing date 2019-12-09
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 193121-0
    ISSN 1600-0536 ; 0105-1873
    ISSN (online) 1600-0536
    ISSN 0105-1873
    DOI 10.1111/cod.13434
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1116: Show issues Location:
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  7. Article ; Online: Biosignatures of defective sebaceous gland activity in sebum-rich and sebum-poor skin areas in adult atopic dermatitis.

    Cavallo, Alessia / Camera, Emanuela / Bottillo, Grazia / Maiellaro, Miriam / Truglio, Mauro / Marini, Federico / Chavagnac-Bonneville, Marlène / Fauger, Aurélie / Perrier, Eric / Pigliacelli, Flavia / Picardo, Mauro / Cristaudo, Antonio / Mariano, Maria

    Experimental dermatology

    2024  Volume 33, Issue 3, Page(s) e15066

    Abstract: Atopic dermatitis (AD) is a composite disease presenting disruption of the skin permeability barrier (SPB) in the stratum corneum (SC). Recent evidence supports derangement of the sebaceous gland (SG) activity in the AD pathomechanisms. The objective of ... ...

    Abstract Atopic dermatitis (AD) is a composite disease presenting disruption of the skin permeability barrier (SPB) in the stratum corneum (SC). Recent evidence supports derangement of the sebaceous gland (SG) activity in the AD pathomechanisms. The objective of this study was to delineate profiles of both sebaceous and epidermal lipids and of aminoacids from SG-rich (SGR) and SG-poor (SGP) areas in AD. Both sebum and SC were sampled from SGR areas, while SC was sampled also from SGP areas in 54 adult patients with AD, consisting of 34 and 20 subjects, respectively with and without clinical involvement of face, and in 44 age and sex-matched controls. Skin biophysics were assessed in all sampling sites. Disruption of the SBP was found to be associated with dysregulated lipidome. Abundance of sapienate and lignocerate, representing, respectively, sebum and the SC type lipids, were decreased in sebum and SC from both SGR and SGP areas. Analogously, squalene was significantly diminished in AD, regardless the site. Extent of lipid derangement in SGR areas was correlated with the AD severity. The abundance of aminoacids in the SC from SGR areas was altered more than that determined in SGP areas. Several gender-related differences were found in both controls and AD subgroups. In conclusion, the SG activity was differently compromised in adult females and males with AD, in both SGR and SGP areas. In AD, alterations in the aminoacidome profiles were apparent in the SGR areas. Lipid signatures in association with aminoacidome and skin physical properties may serve the definition of phenotype clusters that associate with AD severity and gender.
    MeSH term(s) Male ; Adult ; Female ; Humans ; Dermatitis, Atopic ; Sebum ; Sebaceous Glands ; Skin ; Lipids
    Chemical Substances Lipids
    Language English
    Publishing date 2024-03-27
    Publishing country Denmark
    Document type Journal Article
    ZDB-ID 1130936-2
    ISSN 1600-0625 ; 0906-6705
    ISSN (online) 1600-0625
    ISSN 0906-6705
    DOI 10.1111/exd.15066
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    Zs.A 3508: Show issues Location:
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  8. Article ; Online: LASER safety measures for the treatment of genital warts in HIV+ patients during the COVID-19 pandemic.

    Cameli, Norma / Mariano, Maria / Latini, Alessandra / Morrone, Aldo / Cristaudo, Antonio

    Dermatologic therapy

    2020  Volume 33, Issue 4, Page(s) e13750

    MeSH term(s) Betacoronavirus ; COVID-19 ; Comorbidity ; Condylomata Acuminata/epidemiology ; Condylomata Acuminata/surgery ; Coronavirus Infections/epidemiology ; HIV ; HIV Infections/epidemiology ; Humans ; Laser Therapy/methods ; Pandemics ; Pneumonia, Viral/epidemiology ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-07-03
    Publishing country United States
    Document type Letter
    ZDB-ID 1354801-3
    ISSN 1529-8019 ; 1396-0296
    ISSN (online) 1529-8019
    ISSN 1396-0296
    DOI 10.1111/dth.13750
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  9. Article: Ribociclib-Induced Erythema Dyschromicum Perstans (Ashy Dermatosis)-Like Pigmentation in a Metastatic Breast Cancer Patient.

    Mariano, Maria / Donati, Pietro / Cameli, Norma / Pigliacelli, Flavia / Morrone, Aldo / Cristaudo, Antonio

    Journal of breast cancer

    2021  Volume 24, Issue 1, Page(s) 117–121

    Abstract: Ribociclib is a selective cyclin-dependent kinase (CDK) 4/6 inhibitor that has been approved in combination with endocrine therapy for the treatment of hormone receptor-positive/human epidermal growth factor 2-negative advanced or metastatic breast ... ...

    Abstract Ribociclib is a selective cyclin-dependent kinase (CDK) 4/6 inhibitor that has been approved in combination with endocrine therapy for the treatment of hormone receptor-positive/human epidermal growth factor 2-negative advanced or metastatic breast cancer. The main dermatological adverse events associated with CDK 4/6 inhibitors that are described in the literature include skin rash, an increased risk of alopecia, and stomatitis. Erythema dyschromicum perstans (EDP), also known as ashy dermatosis, is characterized by acquired small and large slate-gray hyperpigmented macules with erythematous borders. There are currently no published reports of EDP-like or pigmentary changes induced by CDK 4/6 inhibitors. This report describes the first case of EDP-like pigmentation associated with ribociclib therapy.
    Language English
    Publishing date 2021-02-26
    Publishing country Korea (South)
    Document type Case Reports
    ZDB-ID 2559753-X
    ISSN 2092-9900 ; 1738-6756
    ISSN (online) 2092-9900
    ISSN 1738-6756
    DOI 10.4048/jbc.2021.24.e1
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    Zs.A 6866: Show issues Location:
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  10. Article ; Online: Morphea induced by SARS-CoV-2 infection: A case report.

    Pigliacelli, Flavia / Pacifico, Alessia / Mariano, Maria / D'Arino, Andrea / Cristaudo, Antonio / Iacovelli, Paolo

    International journal of dermatology

    2021  Volume 61, Issue 3, Page(s) 377–378

    MeSH term(s) COVID-19 ; Humans ; SARS-CoV-2 ; Scleroderma, Localized
    Language English
    Publishing date 2021-11-15
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.15983
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