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  1. AU="Cuenca-Estrella, Manuel"
  2. AU="Liljeström, Simon"
  3. AU="de Beltrán, Paula"
  4. AU="Bhatti, Asim"
  5. AU="Giménez Pardo, Consuelo"
  6. AU=Pollock Jennifer S AU=Pollock Jennifer S
  7. AU=Yakar Halil Ibrahim
  8. AU="O'Hara, Montana"
  9. AU="Connor, Jean A"
  10. AU="Wozniak, Kinga A"
  11. AU="Manjila, Sunil"
  12. AU="Gaviria-Cantin, Tania"
  13. AU="Pickett, Brett E"
  14. AU="Lee, Seung Yeol"
  15. AU="Waters, Aubri M"
  16. AU="Tremblay, Cyntia"
  17. AU="Sharafeldin, Tamer A"
  18. AU="Alladio, Francesca"
  19. AU="Cheng, Zhiluo"
  20. AU="Silva, Dândara Santos"
  21. AU="Timmann, Dagmar"
  22. AU="Jingping, Lin"
  23. AU="Yoon, Sangwook"
  24. AU="Sedor, John R."
  25. AU="Legrand, Julien"
  26. AU="Mintz, Kevin Todd"
  27. AU="Kösters, Markus"
  28. AU="Castano-Duque, Lina"
  29. AU="Lowry, Gregory V"
  30. AU="Gao, Xiaojuan"
  31. AU="Daniłowicz-Szymanowicz, Ludmiła"
  32. AU="Weber, Jesse N"
  33. AU="Fages-Masmiquel, Ester"
  34. AU="Macias Gil, Raul"
  35. AU="Planchat, Arnaud"
  36. AU="McElrath, Erin E"
  37. AU="Koji Ueda"
  38. AU="Pillas, Diana J"
  39. AU="Thomson, Jason J"
  40. AU="Mitra, Kalyan"
  41. AU="Sanjay Desai"
  42. AU=Cox David J AU=Cox David J
  43. AU="Grebenok, Robert J."
  44. AU="Blackburne, Brittney"
  45. AU="Bortoleti, Bruna Taciane da Silva"
  46. AU="Ehrbar, Martin"
  47. AU="Lepre, Davide"
  48. AU="Olszewska, Zuzanna"
  49. AU="Vojta, Leslie"
  50. AU=Wickstrom Eric AU=Wickstrom Eric
  51. AU="Gangavarapu, Sridevi"
  52. AU="Hussein, Hazem Abdelwaheb"
  53. AU=Cai Yixin AU=Cai Yixin
  54. AU="Hüls, Anke"
  55. AU="Poondru, Srinivasu"
  56. AU="Coca, Daniel"
  57. AU="Lebeau, Paul"
  58. AU="Dehghani, Sedigheh"
  59. AU="Ishibashi, Kenji"
  60. AU="Xu, Yanhua"
  61. AU="Matera, Katarzyna"
  62. AU="Ait-Ouarab, Slimane"
  63. AU="Nicola, Coppede"
  64. AU="Dewitt, John M"
  65. AU="Sorin M. Dudea"
  66. AU="Tanusha D. Ramdin"
  67. AU="Hao, Zehui"
  68. AU="Chauhan, Aman"

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  1. Artikel ; Online: Defining standards of CARE for invasive fungal diseases in the ICU.

    Cuenca-Estrella, Manuel / Kett, Daniel H / Wauters, Joost

    The Journal of antimicrobial chemotherapy

    2019  Band 74, Heft Suppl 2, Seite(n) ii9–ii15

    Abstract: The aim of this article is to review the current recommendations for the diagnosis and treatment of invasive fungal infection in the ICU setting and to explore whether there are standards of care for this patient population. The text focuses mainly on ... ...

    Abstract The aim of this article is to review the current recommendations for the diagnosis and treatment of invasive fungal infection in the ICU setting and to explore whether there are standards of care for this patient population. The text focuses mainly on the two most common invasive fungal diseases that afflict non-neutropenic patients: candidaemia and invasive candidosis (IC), and invasive pulmonary aspergillosis (IPA).
    Mesh-Begriff(e) Antifungal Agents/therapeutic use ; Aspergillus/genetics ; Candida/genetics ; Candidiasis, Invasive/diagnosis ; Candidiasis, Invasive/drug therapy ; Congresses as Topic ; Humans ; Intensive Care Units/standards ; Invasive Fungal Infections/diagnosis ; Invasive Fungal Infections/drug therapy ; Invasive Pulmonary Aspergillosis/diagnosis ; Invasive Pulmonary Aspergillosis/drug therapy ; Practice Guidelines as Topic ; Standard of Care
    Chemische Substanzen Antifungal Agents
    Sprache Englisch
    Erscheinungsdatum 2019-06-19
    Erscheinungsland England
    Dokumenttyp Journal Article ; Review
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkz038
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  2. Artikel ; Online: An introduction to current standards of CARE in invasive fungal disease.

    Richardson, Malcolm D / Cuenca-Estrella, Manuel / Maertens, Johan

    The Journal of antimicrobial chemotherapy

    2019  Band 74, Heft Suppl 2, Seite(n) ii2

    Abstract: Invasive fungal infections are life-threatening conditions that require rapid diagnosis and optimal management to alleviate their high morbidity and mortality. They are also associated with a high economic burden, owing to prolonged hospitalization, the ... ...

    Abstract Invasive fungal infections are life-threatening conditions that require rapid diagnosis and optimal management to alleviate their high morbidity and mortality. They are also associated with a high economic burden, owing to prolonged hospitalization, the need for intensive supportive care, and the consumption of costly new antifungal agents. Many standards of care and guidelines have been published by national and international medical societies and organizations over the past 20 years that have embraced new diagnostic technologies and strategies, and new antifungal drugs. Recognizing the ongoing need and debate on the topic of standards for optimal diagnostics and patient care, the Scientific Committee of the Continuing Antifungal Research and Education (CARE) programme devised the scientific agenda for the 10th CARE (CARE X) meeting to review current practice and recommendations. Specialists in haematology, infectious diseases, medical microbiology and medical mycology met in Barcelona in November 2017. The meeting was organized and funded by Gilead Sciences Europe Ltd.
    Mesh-Begriff(e) Antifungal Agents/therapeutic use ; Congresses as Topic ; Humans ; Invasive Fungal Infections/drug therapy ; Societies, Medical ; Spain ; Standard of Care
    Chemische Substanzen Antifungal Agents
    Sprache Englisch
    Erscheinungsdatum 2019-07-12
    Erscheinungsland England
    Dokumenttyp Introductory Journal Article
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkz036
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  3. Artikel ; Online: In vitro activity of olorofim against clinical isolates of Scedosporium species and Lomentospora prolificans using EUCAST and CLSI methodologies.

    Rivero-Menendez, Olga / Cuenca-Estrella, Manuel / Alastruey-Izquierdo, Ana

    The Journal of antimicrobial chemotherapy

    2020  Band 75, Heft 12, Seite(n) 3582–3585

    Abstract: Objectives: To evaluate the in vitro activity of olorofim, a new broad-spectrum antifungal with a novel mechanism of action, against a collection of 123 Spanish clinical isolates belonging to five Scedosporium species and Lomentospora prolificans.: ... ...

    Abstract Objectives: To evaluate the in vitro activity of olorofim, a new broad-spectrum antifungal with a novel mechanism of action, against a collection of 123 Spanish clinical isolates belonging to five Scedosporium species and Lomentospora prolificans.
    Methods: The activity of olorofim against Scedosporium apiospermum (n = 30), Scedosporium boydii (n = 30), Scedosporium ellipsoideum (n = 10), Scedosporium aurantiacum (n = 20), Scedosporium dehoogii (n = 3) and Lomentospora prolificans (n = 30) was compared with that of amphotericin B, voriconazole, isavuconazole and micafungin by performing EUCAST and CLSI reference methods for antifungal susceptibility testing.
    Results: Amphotericin B and isavuconazole showed MICs ≥2 mg/L for all the species evaluated and voriconazole was moderately active (GM, MIC50 and MIC90 values ≤2 mg/L) against all of them except L. prolificans. Micafungin was effective against S. apiospermum complex strains, but exhibited elevated MECs for S. dehoogii and S. aurantiacum. Olorofim showed low MICs for all the Scedosporium strains tested (GM values were lower than 0.130 and 0.339 by the EUCAST method and the CLSI method, respectively, for all of the species), including those belonging to the MDR species L. prolificans, for which GM values were 0.115 and 0.225 mg/L by the EUCAST method and the CLSI method, respectively, while the GMs for the rest of the antifungals evaluated were higher than 3.732 mg/L using both methodologies.
    Conclusions: Olorofim displayed promising in vitro activity against the Scedosporium and L. prolificans strains tested, some of which have reduced susceptibility to the antifungals that are currently in use.
    Mesh-Begriff(e) Acetamides ; Antifungal Agents/pharmacology ; Microbial Sensitivity Tests ; Piperazines ; Pyrimidines ; Pyrroles ; Scedosporium
    Chemische Substanzen Acetamides ; Antifungal Agents ; Piperazines ; Pyrimidines ; Pyrroles ; olorofim (T34SH2H9HI)
    Sprache Englisch
    Erscheinungsdatum 2020-06-17
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkaa351
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  4. Artikel ; Online: In Vitro Activity of Ibrexafungerp against a Collection of Clinical Isolates of

    Rivero-Menendez, Olga / Soto-Debran, Juan Carlos / Cuenca-Estrella, Manuel / Alastruey-Izquierdo, Ana

    Journal of fungi (Basel, Switzerland)

    2021  Band 7, Heft 3

    Abstract: Ibrexafungerp is a new orally-available 1,3-β-D-glucan synthesis inhibitor in clinical development. Its in vitro activity and that of amphotericin B, voriconazole, and micafungin were evaluated against a collection of 168 clinical isolates ... ...

    Abstract Ibrexafungerp is a new orally-available 1,3-β-D-glucan synthesis inhibitor in clinical development. Its in vitro activity and that of amphotericin B, voriconazole, and micafungin were evaluated against a collection of 168 clinical isolates of
    Sprache Englisch
    Erscheinungsdatum 2021-03-20
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2784229-0
    ISSN 2309-608X ; 2309-608X
    ISSN (online) 2309-608X
    ISSN 2309-608X
    DOI 10.3390/jof7030232
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  5. Buch ; Online: Programa académico. SEMINARIO COVID-19

    Cuenca-Estrella, Manuel / Belda-Iniesta, Cristobal

    la epidemiología, la microbiología y la investigación en las estrategias de vigilancia y control de la pandemia. Universidad Internacional Menéndez Pelayo del 27 y 28 agosto de 2020

    2020  

    Abstract: La pandemia por COVID-19 está provocando millones de casos en el todo el mundo, con una mortalidad relevante. El impacto de la infección ha sido devastador y podrían producirse nuevas ondas epidémicas. Para detectar precozmente estas nuevas ondas y ... ...

    Abstract La pandemia por COVID-19 está provocando millones de casos en el todo el mundo, con una mortalidad relevante. El impacto de la infección ha sido devastador y podrían producirse nuevas ondas epidémicas. Para detectar precozmente estas nuevas ondas y controlar eficazmente sus efectos, deben desarrollarse e implementarse sistemas epidemiológicos y biológicos de vigilancia, y que estos sistemas puedan incorporar los hallazgos de las numerosas iniciativas investigadoras que existen por todo el mundo. El seminario va dirigido a profesionales sanitarios en general, con especial orientación a trabajadores de la salud pública: epidemiólogos, microbiólogos, infectólogos y otras especialidades sanitarias directamente implicadas en el control de la pandemia. También debería interesar a investigadores y científicos con proyectos en este campo de conocimiento, sociedades científicas, organizaciones y público en general que puedan estar implicados en los diferentes aspectos de COVID-19.

    No
    Schlagwörter Coronavirus ; COVID-19 ; SARS- Cov_2 ; covid19
    Sprache Spanisch
    Erscheinungsdatum 2020-08-27
    Erscheinungsland es
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Artikel ; Online: Diagnóstico de laboratorio de la enfermedad fúngica invasora.

    Cuenca-Estrella, Manuel

    Enfermedades infecciosas y microbiologia clinica

    2012  Band 30, Heft 5, Seite(n) 257–264

    Abstract: A number of newer diagnostic procedures have been developed over the last few years as alternatives to conventional microbiological methods to detect invasive fungal diseases (IFD). This text reviews the performance of alternative methods in clinical ... ...

    Titelübersetzung Laboratory diagnosis of fungal infection diseases.
    Abstract A number of newer diagnostic procedures have been developed over the last few years as alternatives to conventional microbiological methods to detect invasive fungal diseases (IFD). This text reviews the performance of alternative methods in clinical settings, and their accuracy compared with that of microscopical examination and microbiological cultures. Some newer techniques considered as complementary and experimental procedures are also reviewed. The text is divided into three sections, including Candida infections, aspergillosis and infections due to rare and emerging fungal species.
    Mesh-Begriff(e) Aspergillosis/diagnosis ; Candidiasis, Invasive/diagnosis ; Clinical Laboratory Techniques ; Humans ; Mycoses/diagnosis ; Mycoses/microbiology
    Sprache Spanisch
    Erscheinungsdatum 2012-05
    Erscheinungsland Spain
    Dokumenttyp English Abstract ; Journal Article
    ZDB-ID 1070941-1
    ISSN 1578-1852 ; 0213-005X
    ISSN (online) 1578-1852
    ISSN 0213-005X
    DOI 10.1016/j.eimc.2012.01.019
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    Zs.A 3204: Hefte anzeigen Standort:
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  7. Artikel ; Online: In vitro activity of APX001A against rare moulds using EUCAST and CLSI methodologies.

    Rivero-Menendez, Olga / Cuenca-Estrella, Manuel / Alastruey-Izquierdo, Ana

    The Journal of antimicrobial chemotherapy

    2019  Band 74, Heft 5, Seite(n) 1295–1299

    Abstract: Background: APX001A (E1210) is a novel broad-spectrum antifungal agent that inhibits Gwt1p, a protein that plays an important role in fungal cell wall integrity. Previous studies have shown that APX001A has broad activity against most species of Candida, ...

    Abstract Background: APX001A (E1210) is a novel broad-spectrum antifungal agent that inhibits Gwt1p, a protein that plays an important role in fungal cell wall integrity. Previous studies have shown that APX001A has broad activity against most species of Candida, Aspergillus, Scedosporium, Fusarium and Mucorales.
    Objectives: To investigate the in vitro activity of APX001A against 200 isolates belonging to 20 different species of Fusarium, Scedosporium, Lomentospora, Alternaria, cryptic species of Aspergillus and Mucorales.
    Methods: APX001A and comparators were tested using EUCAST and CLSI methodologies for broth microdilution susceptibility testing of antifungal agents.
    Results: APX001A was generally inactive against Mucorales, but active against all cryptic species of Aspergillus and Scedosporium/Lomentospora species.
    Conclusions: APX001A shows encouraging in vitro activity against some emerging fungi that are hard to treat with currently available antifungals.
    Mesh-Begriff(e) Aminopyridines/pharmacology ; Antifungal Agents/pharmacology ; Fungi/drug effects ; Isoxazoles/pharmacology ; Microbial Sensitivity Tests/methods ; Microbial Sensitivity Tests/standards ; Reference Values ; Sensitivity and Specificity
    Chemische Substanzen APX001A ; Aminopyridines ; Antifungal Agents ; Isoxazoles
    Sprache Englisch
    Erscheinungsdatum 2019-01-30
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkz022
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  8. Artikel ; Online: Changes in the epidemiological landscape of invasive mould infections and disease.

    Lass-Flörl, Cornelia / Cuenca-Estrella, Manuel

    The Journal of antimicrobial chemotherapy

    2017  Band 72, Heft suppl_1, Seite(n) i5–i11

    Abstract: Although a wide variety of pathogens are associated with invasive mould diseases, Aspergillus spp. have historically been one of the most common causative organisms. Most invasive mould infections are caused by members of the Aspergillus fumigatus ... ...

    Abstract Although a wide variety of pathogens are associated with invasive mould diseases, Aspergillus spp. have historically been one of the most common causative organisms. Most invasive mould infections are caused by members of the Aspergillus fumigatus species complex and an emerging issue is the occurrence of azole resistance in A. fumigatus, with resistance to amphotericin B documented in other Aspergillus spp. The epidemiology of invasive fungal disease has shifted in recent years as non-A. fumigatus Aspergillus spp. and other moulds have become progressively more important, although there are no consolidated data on the prevalence of less common species of moulds. The incidence of mucormycosis may have been underestimated, which is a potential concern since species belonging to the order Mucorales are more resistant to antifungal agents than Aspergillus spp. All species of Mucorales are unaffected by voriconazole and most show moderate resistance in vitro to echinocandins. Fusarium spp. may be the second most common nosocomial fungal pathogen after Aspergillus in some tertiary hospitals, and show a susceptibility profile marked by a higher level of resistance than that of Aspergillus spp. Recently, Scedosporium aurantiacum has been reported as an emerging opportunistic pathogen, against which voriconazole is the most active antifungal agent. Other mould species can infect humans, although invasive fungal disease occurs less frequently. Since uncommon mould species exhibit individual susceptibility profiles and require tailored clinical management, accurate classification at species level of the aetiological agent in any invasive fungal disease should be regarded as the standard of care.
    Mesh-Begriff(e) Antifungal Agents/therapeutic use ; Aspergillosis/drug therapy ; Aspergillosis/epidemiology ; Aspergillosis/microbiology ; Aspergillus fumigatus/drug effects ; Drug Resistance, Fungal/physiology ; Fusariosis/drug therapy ; Fusariosis/epidemiology ; Fusariosis/microbiology ; Fusarium/drug effects ; Humans ; Immunocompromised Host ; Invasive Fungal Infections/drug therapy ; Invasive Fungal Infections/immunology ; Invasive Fungal Infections/microbiology ; Mucorales/drug effects ; Mucormycosis/drug therapy ; Mucormycosis/epidemiology ; Mucormycosis/microbiology ; Scedosporium/drug effects
    Chemische Substanzen Antifungal Agents
    Sprache Englisch
    Erscheinungsdatum 2017-03-01
    Erscheinungsland England
    Dokumenttyp Journal Article
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkx028
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  9. Artikel ; Online: Triazole Resistance in Aspergillus Species: An Emerging Problem.

    Garcia-Rubio, Rocio / Cuenca-Estrella, Manuel / Mellado, Emilia

    Drugs

    2017  Band 77, Heft 6, Seite(n) 599–613

    Abstract: Aspergillus species are ubiquitous fungal saprophytes found in diverse ecological niches worldwide. Among them, Aspergillus fumigatus is the most prevalent and is largely responsible for the increased incidence of invasive aspergillosis with high ... ...

    Abstract Aspergillus species are ubiquitous fungal saprophytes found in diverse ecological niches worldwide. Among them, Aspergillus fumigatus is the most prevalent and is largely responsible for the increased incidence of invasive aspergillosis with high mortality rates in some immunocompromised hosts. Azoles are the first-line drugs in treating diseases caused by Aspergillus spp. However, increasing reports in A. fumigatus azole resistance, both in the clinical setting and in the environment, are threatening the effectiveness of clinical and agricultural azole drugs. The azole target is the 14-α sterol demethylase encoded by cyp51A gene and the main mechanisms of resistance involve the integration of tandem repeats in its promoter and/or single point mutations in this gene. In A. fumigatus, azole resistance can emerge in two different scenarios: a medical route in which azole resistance is generated during long periods of azole treatment in the clinical setting and a route of resistance derived from environmental origin due to extended use of demethylation inhibitors in agriculture. The understanding of A. fumigatus azole resistance development and its evolution is needed in order to prevent or minimize its impact. In this article, we review the current situation of azole resistance epidemiology and the predominant molecular mechanisms described based on the resistance acquisition routes. In addition, the clinical implications of A. fumigatus azole resistance and future research are discussed.
    Mesh-Begriff(e) Antifungal Agents/administration & dosage ; Antifungal Agents/pharmacology ; Aspergillus fumigatus/drug effects ; Drug Resistance, Fungal/drug effects ; Humans ; Microbial Sensitivity Tests ; Triazoles/administration & dosage ; Triazoles/pharmacology
    Chemische Substanzen Antifungal Agents ; Triazoles
    Sprache Englisch
    Erscheinungsdatum 2017-04
    Erscheinungsland New Zealand
    Dokumenttyp Journal Article ; Review
    ZDB-ID 120316-2
    ISSN 1179-1950 ; 0012-6667
    ISSN (online) 1179-1950
    ISSN 0012-6667
    DOI 10.1007/s40265-017-0714-4
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  10. Artikel ; Online: In vitro activity of olorofim (F901318) against clinical isolates of cryptic species of Aspergillus by EUCAST and CLSI methodologies.

    Rivero-Menendez, Olga / Cuenca-Estrella, Manuel / Alastruey-Izquierdo, Ana

    The Journal of antimicrobial chemotherapy

    2018  Band 74, Heft 6, Seite(n) 1586–1590

    Abstract: Objectives: To investigate the in vitro activity of olorofim (F901318), a novel broad-spectrum antifungal agent, against 150 strains belonging to 16 different cryptic species of Aspergillus by EUCAST and CLSI methodologies.: Methods: Olorofim, ... ...

    Abstract Objectives: To investigate the in vitro activity of olorofim (F901318), a novel broad-spectrum antifungal agent, against 150 strains belonging to 16 different cryptic species of Aspergillus by EUCAST and CLSI methodologies.
    Methods: Olorofim, amphotericin B, micafungin, posaconazole and voriconazole were tested against cryptic species belonging to Aspergillus fumigatus complex (n = 57), Aspergillus ustus complex (n = 25), Aspergillus niger complex (n = 20), Aspergillus flavus complex (n = 20), Aspergillus circumdati complex (n = 15) and Aspergillus terreus complex (n = 13) using EUCAST and CLSI methodologies for broth microdilution susceptibility testing of antifungal agents.
    Results: Olorofim was the only drug with activity against all cryptic species of Aspergillus tested, including the multiresistant species Aspergillus lentulus, Aspergillus fumigatiaffinis and Aspergillus calidoustus. Geometric means of MICs for olorofim were lower (0.017, 0.015 and 0.098 mg/L, respectively, for EUCAST; and 0.015, 0.015 and 0.048 mg/L, respectively, for CLSI) than for amphotericin B (4.438, 12.699 and 0.554 mg/L, respectively, for EUCAST; and 0.758, 1.320 and 0.447 mg/L, respectively, for CLSI), voriconazole (2.549, 2.297 and 5.856 mg/L, respectively, for EUCAST; and 2.071, 1.741 and 5.657 mg/L, respectively, for CLSI) and posaconazole (0.307, 0.308 and 12.996 mg/L, respectively, for EUCAST; and 0.391, 0.215 and 9.514 mg/L, respectively, for CLSI).
    Conclusions: Olorofim shows encouraging in vitro activity against cryptic species of Aspergillus that can be hard to treat with current antifungal therapies. Further studies are warranted in order to assess its efficacy.
    Mesh-Begriff(e) Acetamides/pharmacology ; Antifungal Agents/pharmacology ; Aspergillus/drug effects ; Microbial Sensitivity Tests ; Piperazines/pharmacology ; Pyrimidines/pharmacology ; Pyrroles/pharmacology
    Chemische Substanzen Acetamides ; Antifungal Agents ; Piperazines ; Pyrimidines ; Pyrroles ; olorofim (T34SH2H9HI)
    Sprache Englisch
    Erscheinungsdatum 2018-10-02
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 191709-2
    ISSN 1460-2091 ; 0305-7453
    ISSN (online) 1460-2091
    ISSN 0305-7453
    DOI 10.1093/jac/dkz078
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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